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Aliases for CNTD2 Gene

Aliases for CNTD2 Gene

  • Cyclin N-Terminal Domain Containing 2 2 3
  • Cyclin P 2 3
  • Cyclin N-Terminal Domain-Containing Protein 2 3
  • CCNP 3

External Ids for CNTD2 Gene

Summaries for CNTD2 Gene

GeneCards Summary for CNTD2 Gene

CNTD2 (Cyclin N-Terminal Domain Containing 2) is a Protein Coding gene. GO annotations related to this gene include protein kinase binding.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CNTD2 Gene

Genomics for CNTD2 Gene

Genomic Location for CNTD2 Gene

Start:
40,222,208 bp from pter
End:
40,226,767 bp from pter
Size:
4,560 bases
Orientation:
Minus strand

Genomic View for CNTD2 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for CNTD2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CNTD2 Gene

Regulatory Elements for CNTD2 Gene

Proteins for CNTD2 Gene

  • Protein details for CNTD2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9H8S5-CNTD2_HUMAN
    Recommended name:
    Cyclin N-terminal domain-containing protein 2
    Protein Accession:
    Q9H8S5
    Secondary Accessions:
    • B4DX65

    Protein attributes for CNTD2 Gene

    Size:
    307 amino acids
    Molecular mass:
    33574 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for CNTD2 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for CNTD2 Gene

Proteomics data for CNTD2 Gene at MOPED

Post-translational modifications for CNTD2 Gene

No Post-translational modifications

Other Protein References for CNTD2 Gene

No data available for DME Specific Peptides for CNTD2 Gene

Domains for CNTD2 Gene

Protein Domains for CNTD2 Gene

InterPro:
ProtoNet:

UniProtKB/Swiss-Prot:

CNTD2_HUMAN
Domain:
  • Contains 1 cyclin N-terminal domain.:
    • Q9H8S5
genes like me logo Genes that share domains with CNTD2: view

No data available for Gene Families for CNTD2 Gene

Function for CNTD2 Gene

Gene Ontology (GO) - Molecular Function for CNTD2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0019901 protein kinase binding --
genes like me logo Genes that share ontologies with CNTD2: view
genes like me logo Genes that share phenotypes with CNTD2: view

miRNA for CNTD2 Gene

miRTarBase miRNAs that target CNTD2

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targeting and HOMER Transcription for CNTD2 Gene

Localization for CNTD2 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for CNTD2 Gene COMPARTMENTS Subcellular localization image for CNTD2 gene
Compartment Confidence
mitochondrion 2
cytosol 1
extracellular 1
nucleus 1
peroxisome 1

Gene Ontology (GO) - Cellular Components for CNTD2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus --
genes like me logo Genes that share ontologies with CNTD2: view

Pathways for CNTD2 Gene

SuperPathways for CNTD2 Gene

No Data Available

Interacting Proteins for CNTD2 Gene

Gene Ontology (GO) - Biological Process for CNTD2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000079 regulation of cyclin-dependent protein serine/threonine kinase activity --
GO:0051726 regulation of cell cycle --
genes like me logo Genes that share ontologies with CNTD2: view

No data available for Pathways by source for CNTD2 Gene

Transcripts for CNTD2 Gene

mRNA/cDNA for CNTD2 Gene

(2) REFSEQ mRNAs :
(2) Additional mRNA sequences :
(17) Selected AceView cDNA sequences:
(5) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for CNTD2 Gene

Cyclin N-terminal domain containing 2:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for CNTD2 Gene

ExUns: 1a · 1b ^ 2a · 2b ^ 3a · 3b ^ 4a · 4b ^ 5a · 5b
SP1: - -
SP2: -
SP3: -

Relevant External Links for CNTD2 Gene

GeneLoc Exon Structure for
CNTD2
ECgene alternative splicing isoforms for
CNTD2

Expression for CNTD2 Gene

mRNA expression in normal human tissues for CNTD2 Gene

mRNA differential expression in normal tissues according to GTEx for CNTD2 Gene

This gene is overexpressed in Brain - Cerebellum (10.7), Brain - Cerebellar Hemisphere (10.0), Kidney - Cortex (5.5), and Liver (4.3).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for CNTD2 Gene

SOURCE GeneReport for Unigene cluster for CNTD2 Gene Hs.631603

genes like me logo Genes that share expressions with CNTD2: view

Orthologs for CNTD2 Gene

This gene was present in the common ancestor of mammals.

Orthologs for CNTD2 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia CNTD2 36
  • 98.59 (n)
  • 97.72 (a)
CNTD2 37
  • 98 (a)
OneToOne
cow
(Bos Taurus)
Mammalia CNTD2 36
  • 82.91 (n)
  • 81.39 (a)
CNTD2 37
  • 78 (a)
OneToOne
dog
(Canis familiaris)
Mammalia CNTD2 36
  • 78.94 (n)
  • 77.43 (a)
CNTD2 37
  • 49 (a)
OneToOne
Species with no ortholog for CNTD2:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for CNTD2 Gene

ENSEMBL:
Gene Tree for CNTD2 (if available)
TreeFam:
Gene Tree for CNTD2 (if available)

Paralogs for CNTD2 Gene

Selected SIMAP similar genes for CNTD2 Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with CNTD2: view

No data available for Paralogs for CNTD2 Gene

Variants for CNTD2 Gene

Sequence variations from dbSNP and Humsavar for CNTD2 Gene

SNP ID Clin Chr 19 pos Sequence Context AA Info Type MAF
rs874269 -- 40,226,038(+) CAGAA(C/T)GAGGC intron-variant
rs934426 -- 40,225,464(-) GGAAG(G/T)GTTTT intron-variant
rs2304184 -- 40,222,510(+) GCAAG(G/T)GGTTG utr-variant-3-prime, intron-variant
rs2304185 -- 40,223,028(+) AAAAA(G/T)CAAGT utr-variant-3-prime, intron-variant
rs4239504 -- 40,222,129(+) CCAAT(C/T)AGAGG downstream-variant-500B

Structural Variations from Database of Genomic Variants (DGV) for CNTD2 Gene

Variant ID Type Subtype PubMed ID
dgv1083e1 CNV Complex 17122850
dgv3865n71 CNV Loss 21882294
nsv911699 CNV Loss 21882294
dgv3866n71 CNV Loss 21882294

Relevant External Links for CNTD2 Gene

HapMap Linkage Disequilibrium report
CNTD2

Disorders for CNTD2 Gene

No disorders were found for CNTD2 Gene.

No data available for UniProtKB/Swiss-Prot for CNTD2 Gene

Publications for CNTD2 Gene

  1. Can sequencing shed light on cell cycling? (PMID: 11237006) Murray A.W. … Marks D. (Nature 2001) 2 3
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3 4
  3. The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J. … Lucas S.M. (Nature 2004) 4
  4. Normalization and subtraction: two approaches to facilitate gene discovery. (PMID: 8889548) Bonaldo M.F. … Soares M.B. (Genome Res. 1996) 3

Products for CNTD2 Gene

Sources for CNTD2 Gene

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