CNTD1 Gene
protein-coding GIFtS: 35
GCID: GC17P040950
|
|
cyclin N-terminal domain containing 1(Previous name: cyclin N-terminal domain containing )
(Previous symbol: CNTD)
| |
Aliases
for CNTD1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Cyclin N-Terminal Domain Containing 11 2 | | CNTD1 2 3 | | FLJ401371 | | Cyclin N-Terminal Domain Containing1 | | Cyclin N-Terminal Domain-Containing Protein 12 |
Export aliases for CNTD1 gene to outside databasesPrevious GC identifers: GC17P038207 GC17P036715 |
Summaries
for CNTD1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
-- |
Genomic Views
for CNTD1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000017.10 NC_018928.1 NT_010783.15
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the CNTD1 gene promoter:
STAT1 Pax-5 Pbx1a STAT4 STAT1beta CUTL1 Roaz STAT1alpha STAT2 STAT3
Other transcription factors
Search SABiosciences Chromatin IP Primers for CNTD1
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CNTD1 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 17q21.31 Ensembl cytogenetic band: 17q21.31 HGNC cytogenetic band: 17q21.31CNTD1 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 17 GeneLoc Exon Structure GeneLoc location for GC17P040950: view genomic region
(about GC identifiers)
Start:
|
40,950,810 bp from pter |
End:
|
40,963,605 bp from pter |
Size:
|
12,796 bases |
Orientation:
|
plus strand |
|
Proteins
for CNTD1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: CNTD1_HUMAN, Q8N815 (See
protein sequence)Recommended Name: Cyclin N-terminal domain-containing protein 1 Size: 330 amino acids; 36921 Da
Secondary accessions: Q658Q6 Q8NEP1Alternative splicing: 2 isoforms: Q8N815-1 Q8N815-2 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for CNTD1: NX_Q8N815
CNTD1 Protein expression data from MOPED and PaxDb: --
REFSEQ proteins: NP_775749.2
ENSEMBL proteins: ENSP00000465204 ENSP00000465999 ENSP00000468459 ENSP00000468725 ENSP00000467787
Human Recombinant Protein Products:
CNTD1 Antibody Products:
Assay Products for CNTD1: |
Protein
Domains /
Families
for CNTD1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
CNTD1 for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q8N815ProtoNet protein and cluster: Q8N815 UniProtKB/Swiss-Prot: CNTD1_HUMAN, Q8N815Similarity: Contains 1 cyclin N-terminal domain |
Function
for CNTD1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CNTD1 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CNTD1 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: CNTD1 (NM_173478) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CNTD1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CNTD1 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CNTD1 |
|
Pathways & Interactions
for CNTD1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CNTD1
|
Drugs & Compounds
for CNTD1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for CNTD1
Search CenterWatch for drugs/clinical trials and news about CNTD1
|
Transcripts
for CNTD1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for CNTD1 gene: NM_173478.2 Unigene Cluster for CNTD1: Cyclin N-terminal domain containing 1 Hs.12272 [show with all ESTs]Unigene Representative Sequence: NM_1734787 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000588408 ENST00000585355 ENST00000592166 ENST00000591559 ENST00000588527
ENST00000315066(uc002ibm.4 uc010wha.2) ENST00000586652
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CNTD1 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CNTD1 (see all 2)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: CNTD1 (NM_173478) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CNTD1 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CNTD1 |
Additional cDNA sequence: AK097456.1 AK302094.1 AL833052.1 BC026187.2 10 DOTS entries: DT.449520 DT.97775540 DT.100815253 DT.100028530 DT.75101487 DT.95159053 DT.91649846 DT.95159061 DT.121006688 DT.95159054 24/47 AceView cDNA sequences (see all 47): BQ185208 NM_173478 BE671177 CB104986 AL833052 BC026187 D20904 AA480509 BX096618 AA634378 AK097456 BF195306 BU101610 AA868514 BI828693 AI190582 AW614691 AW173028 AI240077 BV205388 AA757398 AW136558 T27180 AI150202
GeneLoc Exon Structure
2 Alternative Splicing Database (ASD) splice patterns (SP) for CNTD1 About this scheme
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | |
| SP2: | | | | | - | | | | | | | | | | | |
ECgene alternative splicing isoforms for CNTD1
|
Expression
for CNTD1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| CNTD1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --
About this image
Genevestigator expression for CNTD1
SOURCE GeneReport for Unigene cluster: Hs.12272
SABiosciences Custom PCR Arrays for CNTD1
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CNTD1
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat CNTD1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CNTD1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CNTD1 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CNTD1 |
Orthologs
for CNTD1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for CNTD1 gene from 4/11 species (see all 11) About this table
ENSEMBL Gene Tree for CNTD1 (if available)
TreeFam Gene Tree for CNTD1 (if available) |
Paralogs
for CNTD1 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for CNTD1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 17 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for CNTD1 (40950810 - 40963605 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for CNTD1: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CNTD1 |
|
Disorders
/ Diseases
for CNTD1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
| -- |
Publications
for CNTD1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for CNTD1 gene integrated from 9 sources:
(articles sorted by number of sources associating them with CNTD1) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)1 Lamesch P.... Vidal M. (2007)
- The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)2 Bechtel S.... Schupp I. (2007)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
- Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
|
External Searches for CNTD1 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing CNTD1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing CNTD1 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing CNTD1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for CNTD1 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for CNTD1 gene:
Search GeneIP for patents involving CNTD1
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for CNTD1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for CNTD1 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CNTD1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CNTD1 | | | OriGene Protein Over-expression Lysate for CNTD1 | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for CNTD1 | | Browse 3'-UTR reporter clones for miRNA target validation | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CNTD1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CNTD1 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for CNTD1 | | OriGene Custom Protein Services for CNTD1 | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat CNTD1 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CNTD1 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CNTD1 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CNTD1 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CNTD1 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CNTD1 |
| |
 |  |  |  | |
| | | | Search Tocris compounds for CNTD1 |
| |  |  |  |  | | | | |
 |
 |
 |
 | | | CNTD1 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CNTD1 |
|  |  |  | | | | Search ThermoFisher Antibodies for CNTD1 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CNTD1 |
|
|
|
|
