CNOT6L Gene
protein-coding GIFtS: 50
GCID: GC04M078634
|
|
CCR4-NOT transcription complex, subunit 6-like
| |
Aliases
for CNOT6L gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| CCR4-NOT Transcription Complex, Subunit 6-Like1 2 | | CCR4-NOT Transcription Complex Subunit 6-Like2 | | Carbon Catabolite Repressor Protein 4 Homolog B2 3 | | CCR4B3 | | DKFZp434K0981 | | EC 3.1.-.-3 | | CCR4b2 | | |
Export aliases for CNOT6L gene to outside databasesPrevious GC identifers: GC04M078548 GC04M078828 GC04M079030 GC04M079096 GC04M078995 GC04M078853 GC04M074386 |
Summaries
for CNOT6L gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
UniProtKB/Swiss-Prot: CNO6L_HUMAN, Q96LI5Function: Plays a role in the deadenylation of mRNAs in the cytoplasm. Has 3'-5' poly(A) exoribonuclease activity forsynthetic poly(A) RNA substrate. May be involved in the deadenylation-dependent degradation of mRNAs through the3'-UTR AU-rich element-mediated mechanism. Involved in deadenylation-dependent degradation of CDKN1B mRNA
|
Genomic Views
for CNOT6L gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000004.11 NC_018915.1 NT_016354.19
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the CNOT6L gene promoter:
Pax-5 ATF-2 XBP-1 Evi-1 MEF-2A FOXO1a c-Myb c-Jun aMEF-2 FOXO1
Other transcription factors
Search SABiosciences Chromatin IP Primers for CNOT6L
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CNOT6L |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 4q13.3 Ensembl cytogenetic band: 4q21.1 HGNC cytogenetic band: 4q13.3CNOT6L Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 4 GeneLoc Exon Structure GeneLoc location for GC04M078634: view genomic region
(about GC identifiers)
Start:
|
78,634,541 bp from pter |
End:
|
78,740,769 bp from pter |
Size:
|
106,229 bases |
Orientation:
|
minus strand |
|
Proteins
for CNOT6L gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: CNO6L_HUMAN, Q96LI5 (See
protein sequence)Recommended Name: CCR4-NOT transcription complex subunit 6-like Size: 555 amino acids; 63001 Da
Cofactor: Magnesium
Subunit: Component of the CCR4-NOT complex at least composed of CNOT1, CNOT2, CNOT3, CNOT8, CNOT9, CNOT10 and TNKS1BP1.Interacts with NANOS2 (By similarity)
Subcellular location: Cytoplasm
Miscellaneous: Depletion of CNOT6L causes cell growth defect
3 PDB 3D structures from  and Proteopedia  for CNOT6L:3NGN (3D)
3NGO (3D)
3NGQ (3D)
Secondary accessions: Q9UF92Alternative splicing: 2 isoforms: Q96LI5-1 Q96LI5-2 Explore the universe of human proteins at neXtProt for CNOT6L: NX_Q96LI5
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q96LI5
CNOT6L Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_653172.2
ENSEMBL proteins: ENSP00000424896 ENSP00000423750 ENSP00000425571 ENSP00000425836 ENSP00000426320 ENSP00000426269 ENSP00000264903 Reactome Protein details: Q96LI5
Human Recombinant Protein Products:
Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table
CNOT6L for ontologies About GeneDecksing
CNOT6L Antibody Products:
Assay Products for CNOT6L: |
Protein
Domains /
Families
for CNOT6L gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
CNOT6L for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q96LI5ProtoNet protein and cluster: Q96LI5 UniProtKB/Swiss-Prot: CNO6L_HUMAN, Q96LI5Similarity: Belongs to the CCR4/nocturin familySimilarity: Contains 4 LRR (leucine-rich) repeats |
Function
for CNOT6L gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: CNO6L_HUMAN, Q96LI5Function: Plays a role in the deadenylation of mRNAs in the cytoplasm. Has 3'-5' poly(A) exoribonuclease activity forsynthetic poly(A) RNA substrate. May be involved in the deadenylation-dependent degradation of mRNAs through the3'-UTR AU-rich element-mediated mechanism. Involved in deadenylation-dependent degradation of CDKN1B mRNAEnzyme Number (IUBMB): EC 3.1.-.-1
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CNOT6L (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CNOT6L
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: CNOT6L (NM_144571) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CNOT6L | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CNOT6L |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CNOT6L |
Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table
CNOT6L for ontologies About GeneDecksing
|
Pathways & Interactions
for CNOT6L gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Deadenylation-dependent mRNA decay | | | 2 | Metabolism of mRNA | | | 3 | Generic Transcription Pathway | |
Pathway sources
See GeneCards unified pathways
Show all pathways
5 
Reactome Pathways for CNOT6L
1 
Kegg Pathway (Kegg details for CNOT6L):
CNOT6L for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CNOT6L
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/35 Interacting proteins for CNOT6L (Q96LI51, 3 ENSP000002649034) via UniProtKB, MINT, STRING, and/or I2D (see all 35)| Interactant | Interaction Details |
|---|
| GeneCard | External ID(s) |
|---|
| CNOT3 | O751751, 3, ENSP000002212324 | EBI-2562020,EBI-743073 I2D:
score=2 STRING: ENSP00000221232 | | TOB1 | P506161, 3, ENSP000002689574 | EBI-2562020,EBI-723281 I2D:
score=1 STRING: ENSP00000268957 | | CHAF1B | Q131121, 3, ENSP000003157004 | EBI-2562020,EBI-1052944 I2D:
score=1 STRING: ENSP00000315700 | | CNOT1 | A5YKK63, ENSP000003209494 | STRING: ENSP00000320949 I2D:
score=2 | | CHAF1A | Q131113, ENSP000003012804 | I2D:
score=1 STRING: ENSP00000301280 |
About this table
Gene Ontology (GO): 5/7 biological process terms (GO ID links to tree view) (see all 7): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0000288 | nuclear-transcribed mRNA catabolic process, deadenylation-dependent decay |
TAS | -- | | GO:0000289 | nuclear-transcribed mRNA poly(A) tail shortening |
TAS | -- | | GO:0008284 | positive regulation of cell proliferation |
IEA | -- | | GO:0010467 | gene expression |
TAS | -- | | GO:0016070 | RNA metabolic process |
TAS | -- |
CNOT6L for ontologies About GeneDecksing
|
Drugs & Compounds
for CNOT6L gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for CNOT6L
Search CenterWatch for drugs/clinical trials and news about CNOT6L / CNO6L
|
Transcripts
for CNOT6L gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for CNOT6L gene: NM_144571.2 Unigene Cluster for CNOT6L: CCR4-NOT transcription complex, subunit 6-like Hs.592519 [show with all ESTs]Unigene Representative Sequence: NM_1445719 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000504123(uc011ccd.2 uc011cce.1) ENST00000515506 ENST00000512485(uc003hkt.1)
ENST00000504804 ENST00000505983 ENST00000508371 ENST00000506166 ENST00000515441
ENST00000264903(uc003hks.3)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CNOT6L (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CNOT6L
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: CNOT6L (NM_144571) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CNOT6L | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CNOT6L |
Additional cDNA sequence: AK027214.1 AK058188.1 AK124855.1 AK303417.1 AK304397.1 AL133112.1 6 DOTS entries: DT.440915 DT.102842447 DT.121238246 DT.92034579 DT.95266054 DT.121016394 24/93 AceView cDNA sequences (see all 93): AW015325 NM_144571 AI122950 AK058188 AW009246 AW059757 AL133112 AA858187 BQ718655 BM830893 AI268902 AA252689 AA857956 AA294823 AI982915 BG534513 BQ307421 BG500011 CD639863 BQ025327 CD242218 AA749443 CB243925 BQ416804
GeneLoc Exon Structure
5/6 Alternative Splicing Database (ASD) splice patterns (SP) for CNOT6L (see all 6) About this scheme
| ExUns: | 1 | ^ | 2 | ^ | 3a | · | 3b | ^ | 4a | · | 4b | ^ | 5 | ^ | 6a | · | 6b | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10a | · | 10b | ^ | 11a | · | 11b | · | 11c | · | 11d | ^ | 12a | · | 12b |
|---|
|
| SP1: | | | | | | | - | | - | | | | | | | | | | | | - | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | - | | | | | | | | | | | | | | - | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for CNOT6L
|
Expression
for CNOT6L gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| CNOT6L expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: ATGTATAGGG
About this image
See CNOT6L Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for CNOT6L
SOURCE GeneReport for Unigene cluster: Hs.592519
UniProtKB/Swiss-Prot: CNO6L_HUMAN, Q96LI5Tissue specificity: Highly expressed in placenta, skeletal muscle, pancreas, testis and leukocytes. Weakly expressed inheart, spleen and thymus
SABiosciences Custom PCR Arrays for CNOT6L
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CNOT6L
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat CNOT6L | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CNOT6L | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CNOT6L | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CNOT6L |
Orthologs
for CNOT6L gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for CNOT6L gene from 9/31 species (see all 31) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
CNOT6L1 |
CCR4-NOT transcription complex, subunit 6-like |
89.74(n)
96.72(a) |
|
422508 XM_420472.3 XP_420472.3 |
lizard
(Anolis carolinensis) |
Reptilia |
CNOT6L6 |
-- |
93(a) |
1 ↔ 1 |
5(146072836-146092043) |
African clawed frog
(Xenopus laevis) |
Amphibia |
Xl.346212 |
Xenopus laevis transcribed sequence with moderate similarity more |
82.61(n) |
|
BJ062607.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
cnot6l1 |
CCR4-NOT transcription complex, subunit 6-like |
74.82(n)
84.74(a) |
|
553665 NM_001020638.1 NP_001018474.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
twin6 |
twin |
54(a) |
1 → many |
3R(20022615-20047687) |
worm
(Caenorhabditis elegans) |
Secernentea |
ccr-46 |
CCR (yeast CCR4/NOT complex component) homolog fam... |
31(a) |
1 → many |
IV(12361546-12371804) |
baker's yeast
(Saccharomyces cerevisiae) |
Saccharomycetes |
CCR41 |
Ccr4p |
48.82(n)
37.47(a) |
|
851212 NP_009381.1 |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
AT3G585606AT3G585806 |
carbon catabolite repressor protein 4-like 2 |
23(a)21(a) |
many ↔ manymany ↔ many |
3(21650596-21654200) 3(21660598-21664095) |
rice
(Oryza sativa) |
Liliopsida |
---- |
endonuclease/exonuclease/phosphatase family domain...endonuclease/exonuclease/phosphatase family domain... |
22(a)21(a) |
many ↔ manymany ↔ many |
3(3615603-3621204) 10(14285713-14291210) |
ENSEMBL Gene Tree for CNOT6L (if available)
TreeFam Gene Tree for CNOT6L (if available) |
Paralogs
for CNOT6L gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for CNOT6L gene
- ANGEL12 CCRN4L2 PDE122 ANGEL22 CNOT62
4 SIMAP similar genes for CNOT6L using alignment to 6 protein entries: CNO6L_HUMAN (see all proteins):CNOT6 RSU1 LRRC8B ANGEL2
CNOT6L for paralogs About GeneDecksing
1 Pseudogenes.org Pseudogene for CNOT6L
PGOHUM00000251182
|
Genomic Variants
for CNOT6L gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for CNOT6L
2 CNVs: 68750 8449 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CNOT6L |
|
Disorders
/ Diseases
for CNOT6L gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
CNOT6L for disorders About GeneDecksing
3  diseases for CNOT6L: About MalaCardstwinning malaria alcoholism
Human Genome Epidemiology (HuGE) Navigator: CNOT6L (2 documents)
Export disorders for CNOT6L gene to outside databases
|
Publications
for CNOT6L gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for CNOT6L gene, integrated from 9 sources (see all 14):
(articles sorted by number of sources associating them with CNOT6L) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Crystal structure of the human CNOT6L nuclease domain reveals strict poly(A) substrate specificity. (PubMed id 20628353)1, 2 Wang H....Rao Z. (2010)
- Depletion of mammalian CCR4b deadenylase triggers elevation of the p27Kip1 mRNA level and impairs cell growth. (PubMed id 17452450)1, 2 Morita M....Yamamoto T. (2007)
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
- The Ccr4a (CNOT6) and Ccr4b (CNOT6L) deadenylase subu nits of the human Ccr4-Not complex contribute to the prevention of cell death a nd senescence. (PubMed id 21233283)1 Mittal S....Winkler G.S. (2011)
- Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
- A Bayesian approach to genetic association studies wi th family-based designs. (PubMed id 20818722)1 Naylor M.G....Lange C. (2010)
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1 Rose J.E....Uhl G.R. (2010)
- Systematic analysis of human protein complexes identi fies chromosome segregation proteins. (PubMed id 20360068)1 Hutchins J.R....Peters J.M. (2010)
- An atlas of combinatorial transcriptional regulation in mouse and man. (PubMed id 20211142)1 Ravasi T....Hayashizaki Y. (2010)
- Interaction of antiproliferative protein Tob with the CCR4-NOT deadenylase complex. (PubMed id 18377426)1 Miyasaka T....Yamamoto T. (2008)
|
External Searches for CNOT6L gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing CNOT6L gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing CNOT6L gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing CNOT6L gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for CNOT6L | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for CNOT6L gene:
Search GeneIP for patents involving CNOT6L
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for CNOT6L gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
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| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for CNOT6L | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CNOT6L | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CNOT6L | | | OriGene Protein Over-expression Lysate for CNOT6L | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for CNOT6L | | OriGene 3'-UTR Clone for CNOT6L | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CNOT6L | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CNOT6L | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for CNOT6L | | OriGene Custom Protein Services for CNOT6L | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat CNOT6L | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CNOT6L | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CNOT6L | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CNOT6L | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CNOT6L | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CNOT6L |
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| | | | Search Tocris compounds for CNOT6L |
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 | | | CNOT6L Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CNOT6L |
|  |  |  | | | | ThermoFisher Antibodies for CNOT6L |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CNOT6L |
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