Aliases for CNOT6 Gene
Aliases for CNOT6 Gene
External Ids for CNOT6 Gene
- HGNC: 14099
- Entrez Gene: 57472
- Ensembl: ENSG00000113300
- OMIM: 608951
- UniProtKB: Q9ULM6
Previous GeneCards Identifiers for CNOT6 Gene
- GC00U990842
- GC05P179855
- GC05P179856
- GC05P179921
- GC05P174644
Summaries for CNOT6 Gene
-
This gene encodes the catalytic component of the CCR4-NOT core transcriptional regulation complex. The encoded protein has a 3'-5' RNase activity and prefers polyadenylated substrates. The CCR4-NOT complex plays a role in many cellular processes, including miRNA-mediated repression, mRNA degradation, and transcriptional regulation. [provided by RefSeq, Dec 2014]
GeneCards Summary for CNOT6 Gene
CNOT6 (CCR4-NOT Transcription Complex Subunit 6) is a Protein Coding gene. Among its related pathways are Gene Expression and Deadenylation-dependent mRNA decay. GO annotations related to this gene include RNA binding and poly(A)-specific ribonuclease activity. An important paralog of this gene is PDE12.
UniProtKB/Swiss-Prot for CNOT6 Gene
-
Poly(A) nuclease with 3-5 RNase activity. Catalytic component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Involved in mRNA decay mediated by the major-protein-coding determinant of instability (mCRD) of the FOS gene in the cytoplasm. In the presence of ZNF335, enhances ligand-dependent transcriptional activity of nuclear hormone receptors, including RARA. The increase of ligand-dependent ESR1-mediated transcription is much smaller, if any. Mediates cell proliferation and cell survival and prevents cellular senescence.
No data available for Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CNOT6 Gene
Genomics for CNOT6 Gene
Regulatory Elements for CNOT6 Gene
Enhancers for CNOT6 Gene
| GeneHancer Identifier | Score | Enhancer Sources | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites within enhancer | Other Gene Targets for Enhancer |
|---|
Enhancers around CNOT6 on UCSC Golden Path with GeneCards custom track
Promoters for CNOT6 Gene
| Ensembl Regulatory Elements (ENSRs) | TSS Distance (bp) | Size (bp) | Binding Sites for Transcription Factors within promoters |
|---|
ENSRs around CNOT6 on UCSC Golden Path with GeneCards custom track
- Transcription factor binding sites by QIAGEN in the CNOT6 gene promoter:
Regulatory Element Products
Genomic Location for CNOT6 Gene
- Chromosome:
- 5
- Start:
- 180,494,373 bp from pter
- End:
- 180,578,405 bp from pter
- Size:
- 84,033 bases
- Orientation:
- Plus strand
Genomic View for CNOT6 Gene
Genes around CNOT6 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 5q35.3 by Ensembl
- 5q35.3 by Entrez Gene
- 5q35.3 by HGNC
CNOT6 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for CNOT6 Gene
Proteins for CNOT6 Gene
-
Protein details for CNOT6 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q9ULM6-CNOT6_HUMAN
- Recommended name:
- CCR4-NOT transcription complex subunit 6
- Protein Accession:
- Q9ULM6
- A7MD46
- D3DWR0
Protein attributes for CNOT6 Gene
- Size:
- 557 amino acids
- Molecular mass:
- 63307 Da
- Cofactor:
- Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
- Quaternary structure:
-
- Component of the CCR4-NOT complex; distinct complexes seem to exist that differ in the participation of probably mutually exclusive catalytic subunits; the complex contains two deadenylase subunits, CNOT6 or CNOT6L, and CNOT7 or CNOT8. Interacts with UNR and ZNF335.
Protein Expression for CNOT6 Gene
Post-translational modifications for CNOT6 Gene
Other Protein References for CNOT6 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Cell Signaling Technology (CST) Antibodies for CNOT6 (CNOT6)
-
Custom Antibody ServicesOriGene Antibodies for CNOT6
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- Abcam antibodies for CNOT6
- antibodies-online Antibodies for CNOT6: See all 34
- GeneTex CNOT6 antibody for CNOT6
-
Santa Cruz Biotechnology (SCBT) Antibodies for CNOT6
Protein Products
-
OriGene Purified Proteins for CNOT6
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- Novus Biologicals proteins for CNOT6
- antibodies-online Proteins for CNOT6: See all 5
- Search antibodies-online for peptides
- Search GeneTex for Proteins for CNOT6
- Abcam proteins for CNOT6
Assay Products
- antibodies-online Kits for CNOT6: See all 9
Domains & Families for CNOT6 Gene
Gene Families for CNOT6 Gene
Protein Domains for CNOT6 Gene
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for CNOT6 Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q9ULM6UniProtKB/Swiss-Prot:
CNOT6_HUMAN :- Belongs to the CCR4/nocturin family.
- Contains 4 LRR (leucine-rich) repeats.
- Family:
-
- Belongs to the CCR4/nocturin family.
- Similarity:
-
- Contains 4 LRR (leucine-rich) repeats.
Function for CNOT6 Gene
Molecular function for CNOT6 Gene
- UniProtKB/Swiss-Prot CatalyticActivity:
- Exonucleolytic cleavage of poly(A) to 5-AMP.
- UniProtKB/Swiss-Prot Function:
- Poly(A) nuclease with 3-5 RNase activity. Catalytic component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Involved in mRNA decay mediated by the major-protein-coding determinant of instability (mCRD) of the FOS gene in the cytoplasm. In the presence of ZNF335, enhances ligand-dependent transcriptional activity of nuclear hormone receptors, including RARA. The increase of ligand-dependent ESR1-mediated transcription is much smaller, if any. Mediates cell proliferation and cell survival and prevents cellular senescence.
Enzyme Numbers (IUBMB) for CNOT6 Gene
- EC 3.1.13.4 63 4
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0004532 | exoribonuclease activity | IDA | 11889047 |
Phenotypes for CNOT6 Gene
- MGI mutant phenotypes for CNOT6:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for CNOT6:
Animal Models for CNOT6 Gene
- MGI Knock Outs for CNOT6:
-
- Cnot6 tm1a(KOMP)Wtsi
Animal Model Products
-
Taconic Biosciences Mouse Models for CNOT6
-
ViGene Biosciences lentiviral particle packaged cDNA for CNOT6 gene
- Search ViGene Biosciences for CNOT6
CRISPR Products
-
OriGene CRISPR knockouts for CNOT6
-
Santa Cruz Biotechnology (SCBT) CRISPR for CNOT6
- GenScript: Design CRISPR guide RNA sequences for CNOT6
miRNA for CNOT6 Gene
- miRTarBase miRNAs that target CNOT6
-
- hsa-mir-1-3p (MIRT003851)
- hsa-mir-373-3p (MIRT004074)
- hsa-mir-193b-3p (MIRT016605)
- hsa-mir-130b-3p (MIRT020329)
- hsa-mir-9-5p (MIRT021485)
- hsa-mir-96-5p (MIRT027912)
- hsa-mir-19b-3p (MIRT031275)
- hsa-mir-15a-3p (MIRT038987)
- hsa-mir-769-5p (MIRT039160)
- hsa-mir-106b-5p (MIRT044283)
- hsa-mir-183-5p (MIRT047042)
- hsa-mir-4314 (MIRT502715)
- hsa-mir-23c (MIRT502716)
- hsa-mir-23b-3p (MIRT502717)
- hsa-mir-23a-3p (MIRT502718)
- hsa-mir-130a-5p (MIRT502719)
- hsa-mir-630 (MIRT502720)
- hsa-mir-6776-5p (MIRT502721)
- hsa-mir-6861-5p (MIRT502722)
- hsa-mir-4717-3p (MIRT502723)
- hsa-mir-4778-5p (MIRT502724)
- hsa-mir-1244 (MIRT502725)
- hsa-mir-186-5p (MIRT502726)
- hsa-mir-155-5p (MIRT513967)
- hsa-mir-621 (MIRT513968)
- hsa-mir-4725-5p (MIRT513969)
- hsa-mir-3146 (MIRT513970)
- hsa-mir-410-3p (MIRT513971)
- hsa-mir-3667-5p (MIRT513972)
- hsa-mir-10a-5p (MIRT513973)
- hsa-mir-10b-5p (MIRT513974)
- hsa-mir-620 (MIRT610032)
- hsa-mir-1270 (MIRT610033)
- hsa-mir-5706 (MIRT610034)
- hsa-mir-4782-5p (MIRT610035)
- hsa-mir-516b-5p (MIRT610036)
- hsa-mir-1299 (MIRT610037)
- hsa-mir-4683 (MIRT610038)
- hsa-mir-8485 (MIRT610039)
- hsa-mir-1238-3p (MIRT716966)
- hsa-mir-670-3p (MIRT716967)
- hsa-mir-6715b-3p (MIRT716968)
- hsa-mir-371a-5p (MIRT716969)
- hsa-mir-4729 (MIRT716970)
- hsa-mir-6715a-3p (MIRT716971)
- hsa-mir-19a-3p (MIRT727971)
miRNA Products
- Search ViGene Biosciences for CNOT6
Clone Products
- OriGene clones in human for CNOT6
- OriGene ORF clones in human,mouse,rat for CNOT6
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Addgene plasmids for CNOT6
Cell Line Products
-
ViGene Biosciences adenoviral particle packaged cDNA for CNOT6 gene
-
ViGene Biosciences lentiviral particle packaged cDNA for CNOT6 gene
- Search ViGene Biosciences for CNOT6
Flow Cytometry Products
No data available for Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for CNOT6 Gene
Localization for CNOT6 Gene
Subcellular locations from UniProtKB/Swiss-Prot for CNOT6 Gene
- Cytoplasm. Nucleus.
| Compartment | Confidence |
|---|---|
| cytosol | 5 |
| nucleus | 4 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0016020 | membrane | IDA | 19946888 |
Pathways & Interactions for CNOT6 Gene
More details on SuperPathways for CNOT6Pathways by source for CNOT6 Gene
1 Cell Signaling Technology pathway for CNOT6 Gene
1 KEGG pathway for CNOT6 Gene
Interacting Proteins for CNOT6 Gene
Selected Interacting proteins:
ENSP00000261951
Q9ULM6-CNOT6_HUMAN
for CNOT6 Gene via
STRING
I2D
UniProtKB
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006355 | regulation of transcription, DNA-templated | IEA | -- |
| GO:0010467 | gene expression | TAS | -- |
| GO:0010606 | positive regulation of cytoplasmic mRNA processing body assembly | IMP | 21233283 |
| GO:0035195 | gene silencing by miRNA | TAS | 20065043 |
| GO:0043928 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay | IDA | 20065043 |
No data available for SIGNOR curated interactions for CNOT6 Gene
Drugs & Compounds for CNOT6 Gene
| Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
|---|---|---|---|---|---|---|
| Magnesium | Nutra | 0 |
Transcripts for CNOT6 Gene
mRNA/cDNA for CNOT6 Gene
- (8) REFSEQ mRNAs :
- (10) Additional mRNA sequences :
- (268) Selected AceView cDNA sequences:
- (7) Ensembl transcripts including schematic representations, and UCSC links where relevant :
Unigene Clusters for CNOT6 Gene
CRISPR Products
-
OriGene CRISPR knockouts for CNOT6
-
Santa Cruz Biotechnology (SCBT) CRISPR for CNOT6
- GenScript: Design CRISPR guide RNA sequences for CNOT6
miRNA Products
- Search ViGene Biosciences for CNOT6
Clone Products
- OriGene clones in human for CNOT6
- OriGene ORF clones in human,mouse,rat for CNOT6
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Addgene plasmids for CNOT6
Flow Cytometry Products
| ExUns: | 1 | ^ | 2a | · | 2b | · | 2c | · | 2d | ^ | 3 | ^ | 4a | · | 4b | ^ | 5a | · | 5b | ^ | 6a | · | 6b | ^ | 7 | ^ | 8a | · | 8b | ^ | 9a | · | 9b | · | 9c | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||
| SP2: | - | ||||||||||||||||||||||||||||||||||||||||||
| SP3: | - | ||||||||||||||||||||||||||||||||||||||||||
| SP4: | |||||||||||||||||||||||||||||||||||||||||||
| SP5: | - | - | - | - | |||||||||||||||||||||||||||||||||||||||
| SP6: | |||||||||||||||||||||||||||||||||||||||||||
| SP7: | - | - | - |
Expression for CNOT6 Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
- Brain (Nervous System)
- Neural Tube (Nervous System)
- Eye (Sensory Organs)
This gene is overexpressed in Plasma (69.0).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MOPED, and MaxQB for CNOT6 Gene
SOURCE GeneReport for Unigene cluster for CNOT6 Gene Hs.608380
- Elite partner
Primer Products
-
OriGene qPCR primer pairs for CNOT6
No data available for mRNA differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for CNOT6 Gene
Orthologs for CNOT6 Gene
This gene was present in the common ancestor of animals and fungi.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| cow (Bos Taurus) |
Mammalia | CNOT6 35 |
|
||
| CNOT6 36 |
|
OneToOne | |||
| dog (Canis familiaris) |
Mammalia | CNOT6 35 |
|
||
| CNOT6 36 |
|
OneToOne | |||
| mouse (Mus musculus) |
Mammalia | Cnot6 35 |
|
||
| Cnot6 16 |
|
||||
| Cnot6 36 |
|
OneToOne | |||
| chimpanzee (Pan troglodytes) |
Mammalia | CNOT6 35 |
|
||
| CNOT6 36 |
|
OneToOne | |||
| rat (Rattus norvegicus) |
Mammalia | Cnot6 35 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | CNOT6 36 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | CNOT6 36 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | CNOT6 35 |
|
||
| CNOT6 36 |
|
OneToOne | |||
| lizard (Anolis carolinensis) |
Reptilia | CNOT6 36 |
|
OneToOne | |
| zebrafish (Danio rerio) |
Actinopterygii | cnot6 35 |
|
||
| Dr.24978 35 |
|
||||
| cnot6 36 |
|
OneToMany | |||
| CNOT6 (2 of 2) 36 |
|
OneToMany | |||
| fruit fly (Drosophila melanogaster) |
Insecta | twin 36 |
|
OneToMany | |
| worm (Caenorhabditis elegans) |
Secernentea | ccr-4 36 |
|
OneToMany | |
| baker's yeast (Saccharomyces cerevisiae) |
Saccharomycetes | CCR4 36 |
|
OneToMany | |
| CCR4 38 |
|
|
|||
| sea squirt (Ciona savignyi) |
Ascidiacea | -- 36 |
|
OneToMany |
- Species with no ortholog for CNOT6:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
Paralogs for CNOT6 Gene
(1) SIMAP similar genes for CNOT6 Gene using alignment to 3 proteins:
Variants for CNOT6 Gene
| SNP ID | Clin | Chr 05 pos | Sequence Context | AA Info | Type |
|---|---|---|---|---|---|
| rs9079 | -- | 180,578,015(-) | TTTTC(C/T)TCAAA | utr-variant-3-prime | |
| rs10069 | -- | 180,576,085(+) | CAGTA(C/T)ATTGG | utr-variant-3-prime | |
| rs14457 | -- | 180,578,209(+) | ATTTT(A/C)TATTT | utr-variant-3-prime | |
| rs15804 | -- | 180,577,829(-) | AGCCC(C/T)TGTTA | utr-variant-3-prime | |
| rs780122 | -- | 180,522,297(-) | tctct(A/C)caaaa | intron-variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| nsv509110 | CNV | Insertion | 20534489 |
| nsv830564 | CNV | Gain | 17160897 |
| esv2731343 | CNV | Deletion | 23290073 |
| nsv519380 | CNV | Loss | 19592680 |
| esv1078210 | CNV | Deletion | 17803354 |
| esv2731344 | CNV | Deletion | 23290073 |
| esv991928 | CNV | Deletion | 20482838 |
| esv998085 | CNV | Deletion | 20482838 |
| esv1787252 | CNV | Deletion | 17803354 |
| nsv823366 | CNV | Loss | 20364138 |
| nsv509111 | CNV | Insertion | 20534489 |
Residual Variation Intolerance Score:
23.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
1.43;
28.12% of all genes are more intolerant (likely to be disease-causing)
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for CNOT6 Gene
Disorders for CNOT6 Gene
Relevant External Links for CNOT6
No disorders were found for CNOT6 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CNOT6 Gene
Publications for CNOT6 Gene
- CCR4, a 3'-5' poly(A) RNA and ssDNA exonuclease, is the catalytic component of the cytoplasmic deadenylase. (PMID: 11889047) Chen J. … Denis C.L. (EMBO J. 2002) 2 3 4 67
- CCR4-NOT deadenylates mRNA associated with complexes in human cells. (PMID: 20065043) Piao X. … Belasco J.G. (Mol. Cell. Biol. 2010) 3 23
- Components of the CCR4-NOT complex function as nuclear hormone receptor coactivators via association with the NRC-interacting Factor NIF-1. (PMID: 18180299) Garapaty S. … Samuels H.H. (J. Biol. Chem. 2008) 3 23
- UNR, a new partner of poly(A)-binding protein, plays a key role in translationally coupled mRNA turnover mediated by the c-fos major coding-region determinant. (PMID: 15314026) Chang T.-C. … Shyu A.-B. (Genes Dev. 2004) 3 23
- Isolation and characterization of human orthologs of yeast CCR4-NOT complex subunits. (PMID: 10637334) Albert T.K. … Timmers H.T.M. (Nucleic Acids Res. 2000) 3 23
Products for CNOT6 Gene
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- Custom Antibody ServicesOriGene Antibodies for CNOT6
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- Browse OriGene Inhibitory RNA Products For CNOT6
- OriGene qPCR primer pairs for CNOT6
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- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
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- GenScript: Design CRISPR guide RNA sequences for CNOT6
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- Cell Signaling Technology (CST) Antibodies for CNOT6 (CNOT6)
- Search for Antibodies & Assays
- Novus Biologicals Antibodies for CNOT6
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- Abcam antibodies for CNOT6
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- Find your target
- Search knockout validated antibodies
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- Taconic Biosciences Mouse Models for CNOT6
- Find your next knockout model in the Taconic Knockout Repository
- Genetically Engineered Models Available Immediately
- Humanized Mice
- Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat
- Addgene plasmids for CNOT6
- antibodies-online Antibodies for CNOT6: See all 34
- antibodies-online Kits for CNOT6: See all 9
- antibodies-online Proteins for CNOT6: See all 5
- Search antibodies-online for peptides
- GeneTex CNOT6 antibody for CNOT6
- Search GeneTex for Proteins for CNOT6
- ViGene Biosciences adenoviral particle packaged cDNA for CNOT6 gene
- ViGene Biosciences lentiviral particle packaged cDNA for CNOT6 gene
- ViGene Biosciences lentiviral particle packaged cDNA for CNOT6 gene
- Search ViGene Biosciences for CNOT6
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- Santa Cruz Biotechnology (SCBT) Antibodies for CNOT6
- Search Santa Cruz Biotechnology (SCBT) for CNOT6 siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for CNOT6
Sources for CNOT6 Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) I2D
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) UniGene
- (28) AceView
- (29) RNAdb
- (30) ASD
- (31) ECgene
- (32) GeneAnnot
- (33) SAGE
- (34) SOURCE
- (35) HomoloGene
- (36) PanEnsembl
- (37) euGenes
- (38) SGD
- (39) FlyBase
- (40) WormBase
- (41) Pseudogene
- (42) DGV
- (43) dbSNP
- (44) HapMap
- (45) GenAtlas
- (46) GeneTests
- (47) HGMD
- (48) GAD
- (49) LSDB
- (50) BGMUT
- (51) HuGE
- (52) eBioscience
- (53) Atlas
- (54) Cell Signaling Technology
- (55) GenBank
- (56) H-invDB
- (57) HORDE
- (58) HUGE
- (59) IMGT
- (60) Leiden
- (61) MILLIPORE
- (62) miRBase
- (63) DME
- (64) Nature
- (65) NCBI
- (66) OriGene
- (67) PubMed
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