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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

CNNM3 Gene

protein-coding   GIFtS: 51
GCID: GC02P097481

Cyclin M3


(Previous symbol: ACDP3)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Cyclin M31 2     cyclin-M32
ACDP31 2 3 5     Metal Transporter CNNM32
Ancient Conserved Domain-Containing Protein 32 3     Cyclin-M33
Ancient Conserved Domain Protein 32     

External Ids:    HGNC: 1041   Entrez Gene: 265052   Ensembl: ENSG000001687637   OMIM: 6078045   UniProtKB: Q8NE013   

Export aliases for CNNM3 gene to outside databases

Previous GC identifers: GC02P095354 GC02P095936 GC02P096949 GC02P096966 GC02P096903 GC02P096845 GC02P091442


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for CNNM3 Gene: 
CNNM3 (cyclin M3) is a protein-coding gene. Diseases associated with CNNM3 include tuberculosis, and prostate cancer. GO annotations related to this gene include protein binding. An important paralog of this gene is CNNM1.

UniProtKB/Swiss-Prot: CNNM3_HUMAN, Q8NE01
Function: Probable metal transporter (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000002.11  NT_022171.15  NC_018913.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the CNNM3 gene promoter:
         SRF   Pbx1a   SRF (504 AA)   NRSF form 1   NRSF form 2   CP2   HOXA5   Pax-4a   
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search SABiosciences Chromatin IP Primers for CNNM3

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CNNM3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2p12-p11.2   Ensembl cytogenetic band:  2q11.2   HGNC cytogenetic band: 2p12-p11.2

CNNM3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CNNM3 gene location

GeneLoc information about chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02P097481:  view genomic region     (about GC identifiers)

Start:
97,481,982 bp from pter      End:
97,501,121 bp from pter
Size:
19,140 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: CNNM3_HUMAN, Q8NE01 (See protein sequence)
Recommended Name: Metal transporter CNNM3  
Size: 707 amino acids; 76119 Da
Subcellular location: Cell membrane; Multi-pass membrane protein (By similarity)
Miscellaneous: Shares weak sequence similarity with the cyclin family, hence its name. However, it has no
cyclin-like function in vivo
Sequence caution: Sequence=AAF86377.1; Type=Erroneous initiation; Sequence=AAH07199.3; Type=Erroneous initiation;
Sequence=BAA90891.1; Type=Frameshift; Positions=315;
Secondary accessions: B3KX67 Q8TBV4 Q96IW4 Q9NRK4 Q9NXW6
Alternative splicing: 3 isoforms:  Q8NE01-1   Q8NE01-2   Q8NE01-3   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for CNNM3: NX_Q8NE01

Explore proteomics data for CNNM3 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q8NE01

  • CNNM3 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    CNNM3 Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_060093.3  NP_951060.1  

    ENSEMBL proteins: 
     ENSP00000366260   ENSP00000305449  

    Human Recombinant Protein Products for CNNM3: 
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    Novus Biologicals CNNM3 Protein
    Novus Biologicals CNNM3 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for CNNM3 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005886plasma membrane IEA--
    GO:0016021integral to membrane IEA--

    CNNM3 for ontologies           About GeneDecksing



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    Cloud-Clone Corp. ELISAs for CNNM3 
    Cloud-Clone Corp. CLIAs for CNNM3


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    2 InterPro protein domains:
     IPR000644 Cysta_beta_synth_core
     IPR002550 DUF21

    Graphical View of Domain Structure for InterPro Entry Q8NE01

    ProtoNet protein and cluster: Q8NE01

    2 Blocks protein domains:
    IPB000644 CBS domain
    IPB002550 CBS


    UniProtKB/Swiss-Prot: CNNM3_HUMAN, Q8NE01
    Similarity: Belongs to the ACDP family
    Similarity: Contains 2 CBS domains
    Similarity: Contains 1 DUF21 domain


    CNNM3 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: CNNM3_HUMAN, Q8NE01
    Function: Probable metal transporter (By similarity)

         Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003677DNA binding ----
    GO:0003899DNA-directed RNA polymerase activity ----
    GO:0005515protein binding IPI16189514
    GO:0030554adenyl nucleotide binding IEA--
         
    CNNM3 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for CNNM3:
     Increased HPV18 LCR reporter a 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for CNNM3 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for CNNM3

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for CNNM3 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for CNNM3 

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat CNNM3
    8/48 QIAGEN miScript miRNA Assays for microRNAs that regulate CNNM3 (see all 48):
    hsa-miR-302d hsa-miR-520e hsa-miR-3194-5p hsa-miR-4254 hsa-miR-106a hsa-miR-877* hsa-miR-372 hsa-miR-93
    SwitchGear 3'UTR luciferase reporter plasmidCNNM3 3' UTR sequence
    Inhib. RNA
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CNNM3

    STRING Interaction Network Preview (showing 5 interactants - click image to see 13)

    5/20 Interacting proteins for CNNM3 (Q8NE011, 2, 3 ENSP000003054494) via UniProtKB, MINT, STRING, and/or I2D (see all 20)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    RBPMSQ930622, 3, ENSP000003401764MINT-68099 I2D: score=5 STRING: ENSP00000340176
    MDFIQ997501, 2, 3, ENSP000002303214EBI-741032,EBI-724076 MINT-67938 I2D: score=5 STRING: ENSP00000230321
    KRTAP4-12Q9BQ662, 3, ENSP000003775824MINT-66811 I2D: score=5 STRING: ENSP00000377582
    PTP4A3O753653, ENSP000003322744I2D: score=2 STRING: ENSP00000332274
    RYKP349253, ENSP000002960844I2D: score=1 STRING: ENSP00000296084
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006351transcription, DNA-dependent ----
    GO:0006811ion transport IEA--

    CNNM3 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for CNNM3

    Search CenterWatch for drugs/clinical trials and news about CNNM3

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for CNNM3 gene (2 alternative transcripts): 
    NM_017623.4  NM_199078.2  

    Unigene Cluster for CNNM3:

    Cyclin M3
    Hs.711617  [show with all ESTs]
    Unigene Representative Sequence: NM_017623
    5 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000377060(uc002swz.3) ENST00000305510(uc002swy.3) ENST00000465224
    ENST00000494595 ENST00000480035
    miRNA
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    8/48 QIAGEN miScript miRNA Assays for microRNAs that regulate CNNM3 (see all 48):
    hsa-miR-302d hsa-miR-520e hsa-miR-3194-5p hsa-miR-4254 hsa-miR-106a hsa-miR-877* hsa-miR-372 hsa-miR-93
    SwitchGear 3'UTR luciferase reporter plasmidCNNM3 3' UTR sequence
    Inhib. RNA
    Products:
         
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    OriGene RNAi products in human, mouse, rat for CNNM3
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    Clone
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    GenScript: all cDNA clones in your preferred vector (see all 2): CNNM3 (NM_017623)
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CNNM3
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CNNM3

    Additional mRNA sequence: 

    AF216965.1 AK000025.1 AK126847.1 BC007199.1 BC018604.1 BC022944.1 BC037272.1 

    11 DOTS entries:

    DT.95085337  DT.100682173  DT.100026231  DT.95262564  DT.95290912  DT.100773988  DT.40112444  DT.120995910 
    DT.99968592  DT.86845565  DT.120995907 

    24/188 AceView cDNA sequences (see all 188):

    BQ643171 BQ054671 BI438732 AW027175 AA864580 NM_017623 BC022944 BQ286674 
    BM052819 AI248206 BM909589 AA338877 BE219848 AA683316 BU859503 AI471327 
    AF216965 BM823802 BC018604 BQ059569 AA193266 AA987274 BE739853 AA761693 

    GeneLoc Exon Structure

    3 Alternative Splicing Database (ASD) splice patterns (SP) for CNNM3    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4a · 4b ^ 5 ^ 6 ^ 7 ^ 8
    SP1:                                -                           
    SP2:              -                 -                           
    SP3:                                                            


    ECgene alternative splicing isoforms for CNNM3

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    CNNM3 expression in normal human tissues (normalized intensities)      CNNM3 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AACCAGGTGG
    CNNM3 Expression
    About this image


    CNNM3 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/5 selected tissues (see all 5) fully expand
     
     Skeletal Muscle (Muscoskeletal System)    fully expand to see all 2 entries
             Mononuclear Myocytes Hyoid Arch Muscles
     
     Blood (Hematopoietic System)
             neutrophils   
     
     Brain (Nervous System)
             cerebellum   
     
     Thymus (Hematopoietic System)
     
     Spleen (Hematopoietic System)

    See CNNM3 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for CNNM3

    SOURCE GeneReport for Unigene cluster: Hs.711617

    UniProtKB/Swiss-Prot: CNNM3_HUMAN, Q8NE01
    Tissue specificity: Widely expressed. Expressed at higher level in heart and spleen

        SABiosciences Custom PCR Arrays for CNNM3
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CNNM3

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals and fungi.

    Orthologs for CNNM3 gene from 7/13 species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Cnnm31 , 5 cyclin M31, 5 86.97(n)1
    88.3(a)1
      1 (15.30 cM)5
    942181  NM_053186.21  NP_444416.21 
     365118675 
    lizard
    (Anolis carolinensis)
    Reptilia CNNM36
    Uncharacterized protein
    60(a)
    1 ↔ 1
    GL343484.1(510126-528446)
    African clawed frog
    (Xenopus laevis)
    Amphibia BJ038331.12   -- 80.63(n)    BJ038331.1 
    zebrafish
    (Danio rerio)
    Actinopterygii LOC1003297211 metal transporter CNNM3-like 59.93(n)
    55.68(a)
      100329721  XM_003199481.1  XP_003199529.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta uex6
    unextended
    26(a)
    1 → many
    2RHet(3136909-3181390)
    worm
    (Caenorhabditis elegans)
    Secernentea C33D12.26
    C52D10.126
    (see all 5)
    Protein C52D10.12
    (see all 5)
    22(a)
    20(a)
    (see all 5)
    many ↔ many
    many ↔ many
    (see all 5)
    X(3041978-3045806)
    IV(17197908-17206845)
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes MAM36
    Protein required for normal mitochondrial morpholo...
    16(a)
    1 → many
    XV(214017-216137)


    ENSEMBL Gene Tree for CNNM3 (if available)
    TreeFam Gene Tree for CNNM3 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for CNNM3 gene
    CNNM12  CNNM22  CNNM42  
    3 SIMAP similar genes for CNNM3 using alignment to 1 protein entry:     CNNM3_HUMAN:
    CNNM2    CNNM4    CNNM1

    CNNM3 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/424 SNPs in CNNM3 are shown (see all 424)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 2 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1906072001,2
    --97482646(+) GGCGGG/TGCTGC 4 G V mis10--------
    rs2005177001,2
    C--97482906(+) GCGGCA/GGCGAC 4 S G mis10--------
    rs116870921,2
    C,A,H--97482908(+) GGCGGC/GGACCC 4 G syn1 ese30--------
    rs2001715071,2
    --97482926(+) GATCTC/GAGCAA 4 L syn10--------
    rs2020128901,2
    --97482967(+) CGTGCG/TCACGC 4 R L mis10--------
    rs1830356201,2
    C--97483057(+) CACGCA/GCATCC 4 H R mis10--------
    rs1511518161,2
    C,F--97483162(+) CATCAC/G/TTCGTT 6 T S I mis12NA EU 5857
    rs1445572841,2
    C,F--97483174(+) CTACAA/GCCATC 4 N S mis11Minor allele frequency- G:0.00NA 4534
    rs342287661,2
    C,F,H--97483211(-) GCGTCC/TAGCTT 4 L syn111Minor allele frequency- T:0.04NS NA CSA WA EU 6841
    rs2003676431,2
    C--97483430(+) CCATCG/TATCAG 2 -- int10--------

    HapMap Linkage Disequilibrium report for CNNM3 (97481982 - 97501121 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 6 variations for CNNM3:    About this table     
    Variant IDTypeSubtypePubMed ID
    dgv650e201CNV Deletion23290073
    dgv4249n71CNV Loss21882294
    nsv874680CNV Loss21882294
    nsv526313CNV Loss19592680
    nsv874677CNV Loss21882294
    esv5003CNV Complex18987735

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing CNNM3
    DNA2.0 Custom Variant and Variant Library Synthesis for CNNM3

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 607804    OMIM disorders: --

    4 diseases for CNNM3:    About MalaCards
    tuberculosis    prostate cancer    prostatitis    breast cancer


    CNNM3 for disorders           About GeneDecksing

    Genetic Association Database (GAD): CNNM3

    Export disorders for CNNM3 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for CNNM3 gene, integrated from 9 sources (see all 27):
    (articles sorted by number of sources associating them with CNNM3)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Genome-wide association study to identify single nucl eotide polymorphisms (SNPs) associated with the development of erectile dysfunc tion in African-American men after radiotherapy for prostate cancer. (PubMed id 20932654)1, 4 Kerns S.L....Rosenstein B.S. (2010)
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    3. Molecular cloning and characterization of a novel gene family of four ancient conserved domain proteins (ACDP). (PubMed id 12657465)1, 2 Wang C.-Y.... She J.-X. (2003)
    4. Interlaboratory reproducibility of large-scale human p rotein-complex analysis by standardized AP-MS. (PubMed id 23455922)1 Varjosalo M....Superti-Furga G. (2013)
    5. Novel, gel-free proteomics approach identifies RNF5 an d JAMP as modulators of GPCR stability. (PubMed id 23798571)1 Roy S.J....Parent J.L. (2013)
    6. Proteome-wide identification of ubiquitylation sites b y conjugation of engineered lysine-less ubiquitin. (PubMed id 22053931)1 Oshikawa K....Nakayama K.I. (2012)
    7. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (2012)
    8. Mapping a dynamic innate immunity protein interaction network regulating type I interferon production. (PubMed id 21903422)1 Li S....Dorf M.E. (2011)
    9. A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
    10. Toward an understanding of the protein interaction net work of the human liver. (PubMed id 21988832)1 Wang J....Yang X. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 26505 HGNC: 104 AceView: CNNM3 Ensembl:ENSG00000168763 euGenes: HUgn26505
    ECgene: CNNM3 H-InvDB: CNNM3

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for CNNM3 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for CNNM3 gene:
    Search GeneIP for patents involving CNNM3

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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