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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

CNNM1 Gene

protein-coding GIFtS: 49
GCID: GC10P101080

cyclin M1

(Previous symbol: ACDP1)

Explore 9 diseases affiliated with
CNNM1 via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Cyclin M1¹ ²		Ancient Conserved Domain Protein 1²
ACDP1¹ ² ³ ⁵		Cyclin-M1³
Ancient Conserved Domain-Containing Protein 1² ³		Metal Transporter CNNM1²
CLP-1²		Cyclin-M1³

External Ids:	HGNC: 102¹	Entrez Gene: 26507²	Ensembl: ENSG00000119946⁷	OMIM: 607802⁵	UniProtKB: Q9NRU3³

Export aliases for CNNM1 gene to outside databases

Previous GC identifers: GC10P099983 GC10P100323 GC10P101221 GC10P100754 GC10P094715

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: CNNM1_HUMAN, Q9NRU3

Function: Probable metal transporter (By similarity)

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_000010.10 NC_018921.1 NT_030059.13

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the CNNM1 gene promoter:
NF-1/L NF-1 Tal-1 Pax-5 Pax-2 Pax-2a c-Ets-1 HEN1 N-Myc Pax-4a
Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: CNNM1 promoter sequence

Search SABiosciences Chromatin IP Primers for CNNM1

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CNNM1

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 10q24.2 Ensembl cytogenetic band: 10q24.2 HGNC cytogenetic band: 10q23-q24

CNNM1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CNNM1 gene location

GeneLoc information about chromosome 10 GeneLoc Exon Structure

GeneLoc location for GC10P101080: view genomic region (about GC identifiers)

Start:	101,088,856 bp from pter	End:	101,154,087 bp from pter
Size:	65,232 bases	Orientation:	plus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: CNNM1_HUMAN, Q9NRU3 (See protein sequence)

Recommended Name: Metal transporter CNNM1

Size: 951 amino acids; 104351 Da

Subcellular location: Cell membrane; Multi-pass membrane protein (By similarity)

Miscellaneous: Shares weak sequence similarity with the cyclin family, hence its name. However, it has no cyclin-like

function in vivo

Sequence caution: Sequence=AAF86357.1; Type=Erroneous initiation; Sequence=AAH98103.2; Type=Erroneous initiation;

Sequence=AAH98279.2; Type=Erroneous initiation; Sequence=AAH98307.2; Type=Erroneous initiation; Sequence=CAB70798.1;

Type=Frameshift; Positions=839, 874;

Secondary accessions: Q4QQG7 Q4QQH8 Q4QQP9 Q9NT45

Alternative splicing: 2 isoforms: Q9NRU3-1 Q9NRU3-2 (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for CNNM1: NX_Q9NRU3

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_Q9NRU3

CNNM1 Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_065081.2

ENSEMBL proteins:

ENSP00000349147 ENSP00000406492 ENSP00000359559 ENSP00000359565

Human Recombinant Protein Products:

	Browse Purified and Recombinant Proteins at EMD Millipore
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	Browse recombinant and purified proteins available from Enzo Life Sciences
	Browse OriGene full length recombinant human proteins expressed in human HEK293 cells Browse OriGene Protein Over-expression Lysates OriGene Custom Protein Services for CNNM1
	GenScript Custom Purified and Recombinant Proteins Services for CNNM1
	Novus Biologicals CNNM1 Protein
	Browse Sino Biological Recombinant Proteins
	Browse ProSpec Recombinant Proteins
	Uscn Proteins for CNNM1

Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005886	plasma membrane	IEA	--
GO:0016021	integral to membrane	IEA	--

CNNM1 for ontologies About GeneDecksing

CNNM1 Antibody Products:

	Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
	Browse R&D Systems for Antibodies
	Browse OriGene Antibodies OriGene Custom Antibody Services for CNNM1
	GenScript Custom Superior Antibodies Services for CNNM1
	Novus Biologicals CNNM1 Antibody
	Search for Antibodies for CNNM1 at Abcam
	Uscn Antibodies for CNNM1
	Search ThermoFisher Antibodies for CNNM1

Assay Products for CNNM1:

	Browse Kits and Assays available from EMD Millipore
	OriGene Custom Immunoassay Development Browse OriGene Fluorogenic Cell Assay Kits
	Browse R&D Systems for biochemical assays
	GenScript Custom Assay Services for CNNM1
	Browse Enzo Life Sciences for kits & assays
	Uscn ELISAs and CLIAs for CNNM1

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

CNNM1 for domains About GeneDecksing

2 InterPro domains/families:

IPR000644 Cysta_beta_synth_core

IPR002550 DUF21

Graphical View of Domain Structure for InterPro Entry Q9NRU3

ProtoNet protein and cluster: Q9NRU3

1 Blocks protein family: IPB000644 CBS domain

UniProtKB/Swiss-Prot: CNNM1_HUMAN, Q9NRU3

Similarity: Belongs to the ACDP family

Similarity: Contains 2 CBS domains

Similarity: Contains 1 DUF21 domain

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Function Summary:

UniProtKB/Swiss-Prot: CNNM1_HUMAN, Q9NRU3

Function: Probable metal transporter (By similarity)

miRNA Products:		OriGene 3'-UTR Clone: CNNM1 Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat CNNM1
		8/70 QIAGEN miScript miRNA Assays for microRNAs that regulate CNNM1 (see all 70):
		hsa-miR-3678-3p hsa-miR-576-3p hsa-miR-376b hsa-miR-631 hsa-miR-759 hsa-miR-3916 hsa-miR-629* hsa-miR-298

		SwitchGear 3'UTR luciferase reporter plasmid: CNNM1 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CNNM1 (see all 7) OriGene shRNA RFP: CNNM1 OriGene siRNA: CNNM1
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CNNM1

Gene Editing
Products:

DNA2.0 Custom Protein Engineering Service for CNNM1

Clone Products:		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CNNM1 (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CNNM1 (see all 2) OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: CNNM1 (NM_020348)
		Browse Sino Biological Human cDNA Clones
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for CNNM1
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CNNM1

Cell Line Products:		GenScript Custom overexpressing Cell Line Services for CNNM1
		Search LifeMap BioReagents cell lines for CNNM1

In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CNNM1

3 GenomeRNAi human phenotypes for CNNM1:

Decreased influenza A H1N1 (A/

Decreased influenza A/WSN/33 r

Increased gamma-H2AX phosphory

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for CNNM1

1 Interacting protein for CNNM1 (Q9NRU3³) via UniProtKB, MINT, STRING, and/or I2D

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
YWHAB	P31946³	I2D: score=1

About this table

Gene Ontology (GO): 1 biological process term (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006811	ion transport	IEA	--

CNNM1 for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for CNNM1
Search CenterWatch for drugs/clinical trials and news about CNNM1

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for CNNM1 gene:

NM_020348.2

Unigene Cluster for CNNM1:

Cyclin M1

Hs.274579 [show with all ESTs]

Unigene Representative Sequence: NM_020348

5 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000356713(uc009xwe.3 uc001kpp.4 uc010qpi.2 uc009xwf.3 uc009xwg.3)

ENST00000488090 ENST00000446890 ENST00000370528 ENST00000370534

miRNA Products:		OriGene 3'-UTR Clone: CNNM1 Browse OriGene MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat CNNM1
		8/70 QIAGEN miScript miRNA Assays for microRNAs that regulate CNNM1 (see all 70):
		hsa-miR-3678-3p hsa-miR-576-3p hsa-miR-376b hsa-miR-631 hsa-miR-759 hsa-miR-3916 hsa-miR-629* hsa-miR-298

		SwitchGear 3'UTR luciferase reporter plasmid: CNNM1 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CNNM1 (see all 7) OriGene shRNA RFP: CNNM1 OriGene siRNA: CNNM1
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CNNM1

Clone Products:		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CNNM1 (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CNNM1 (see all 2) OriGene custom cloning services � gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: CNNM1 (NM_020348)
		DNA2.0 Custom Codon Optimized Gene Synthesis Service for CNNM1
		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CNNM1

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CNNM1 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse / rat CNNM1
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CNNM1
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CNNM1

Additional cDNA sequence:

AF169226.1 AK056194.1 AK296545.1 AK299346.1 AK308326.1 AK308618.1 AK310486.1 AL137536.1

BC098103.1 BC098134.1 BC098279.1 BC098307.1 JF267782.1

4 DOTS entries:

DT.308590 DT.100737928 DT.91748097 DT.91706557

24/35 AceView cDNA sequences (see all 35):

BM932302 BG117179 BM709460 AW296465 AK056194 AF169226 BI870106 NM_020348

BM692809 AL041768 BI868774 AA397733 BU733423 AL137536 BE780768 AA326530

BP369359 BM671372 CA420502 BM714452 AA399647 AL041769 BF963363 AA812661

GeneLoc Exon Structure

5/7 Alternative Splicing Database (ASD) splice patterns (SP) for CNNM1 (see all 7) About this scheme

ExUns:	1a	·	1b	^	2	^	3	^	4	^	5a	·	5b	^	6a	·	6b	^	7	^	8	^	9	^	10a	·	10b	·	10c	^	11	^	12	^	13	^	14a	·	14b
SP1:							-		-		-												-						-
SP2:							-		-		-												-						-				-
SP3:									-		-												-
SP4:
SP5:

ECgene alternative splicing isoforms for CNNM1

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

CNNM1 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CAGGCTTCTT

About this image

CNNM1 expression in embryonic tissues and stem cells

Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

2 LifeMap In Vivo Development Anatomical Compartments/Cells

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Ovary

Ovary

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

See CNNM1 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for CNNM1

SOURCE GeneReport for Unigene cluster: Hs.274579

UniProtKB/Swiss-Prot: CNNM1_HUMAN, Q9NRU3

Tissue specificity: Restricted to brain and testis

SABiosciences Custom PCR Arrays for CNNM1

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CNNM1 Browse OriGene validated miRNA SYBR primer pairs
		SABiosciences RT² qPCR Primer Assay in human, mouse / rat CNNM1
		QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CNNM1
		QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CNNM1

In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CNNM1

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of eukaryotes.

Orthologs for CNNM1 gene from 8/25 species (see all 25) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
chicken (Gallus gallus)	Aves	CNNM1¹	cyclin M1	78.1(n) 81.23(a)		423833 XM_421703.3 XP_421703.3
lizard (Anolis carolinensis)	Reptilia	CNNM1⁶	--	70(a)	1 ↔ 1	3(38493855-38520914)
tropical clawed frog (Xenopus tropicalis)	Amphibia	Str.13101²	Transcribed sequence with weak similarity to protein more	75.12(n)		AL885917.2
zebrafish (Danio rerio)	Actinopterygii	LOC562504¹	metal transporter CNNM2-like	64.09(n) 61.35(a)		562504 XM_001920412.1 XP_001920447.2
fruit fly (Drosophila melanogaster)	Insecta	uex⁶	unextended	32(a)	1 → many	2RHet(3136909-3181390)
worm (Caenorhabditis elegans)	Secernentea	C52D10.12³	--	31(a)		IV(17198349-17206961) --
thale cress (Arabidopsis thaliana)	eudicotyledons	AT4G33700⁶ AT1G03270⁶ (see all 7)	CBS domain-containing protein (see all 7)	26(a) 26(a) (see all 7)	possible ortholog possible ortholog (see all 7)	4(16176276-16179481) 1(799191-802436)
rice (Oryza sativa)	Liliopsida	-- -- (see all 3)	CBS domain containing protein, expressed (see all 3)	26(a) 26(a) (see all 3)	possible ortholog possible ortholog (see all 3)	5(19170330-19177914) 3(26644652-26650901)

ENSEMBL Gene Tree for CNNM1 (if available)
TreeFam Gene Tree for CNNM1 (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for CNNM1 gene

CNNM3² CNNM2² CNNM4²

4 SIMAP similar genes for CNNM1 using alignment to 4 protein entries: CNNM1_HUMAN (see all proteins):

DKFZp434I1016 CNNM4 CNNM2 CNNM3

CNNM1 for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 10 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs140748312^1,2		--	101087101(+)	`CCACTA/TTATTA`	1	--	us2k¹		0	--	--	--	--
rs11190053^1,2	C,F,H,	--	101087268(+)	`CTTAGT/CAAAGG`	1	--	us2k¹		12		NS EA NA WA	782
rs145748282^1,2		--	101087325(+)	`TAATCC/TGGAAA`	1	--	us2k¹		0	--	--	--	--
rs112735074^1,2	F	--	101087340(+)	`AACTAC/TAGGGG`	1	--	us2k¹		2		CSA	4
rs11190054^1,2	C,F,H,	--	101087358(+)	`ATCAGT/CAGTTC`	1	--	us2k¹		12		NS EA NA WA	786
rs189834433^1,2		--	101087578(+)	`ACAATA/GTAAGG`	1	--	us2k¹		0	--	--	--	--
rs7911505^1,2	C,	--	101087580(+)	`AATATA/GAGGAA`	1	--	us2k¹		2		WA	120
rs138422682^1,2		--	101087591(+)	`TTTAAA/TAAGAA`	1	--	us2k¹		0	--	--	--	--
rs183009717^1,2		--	101087604(+)	`TCTCCC/TTCCCA`	1	--	us2k¹		0	--	--	--	--
rs116120078^1,2	F,	--	101087643(+)	`GAGTGC/TAGTGA`	1	--	us2k¹		1		WA	118

HapMap Linkage Disequilibrium report for CNNM1 (101088856 - 101154087 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for CNNM1: --

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CNNM1

DNA2.0 Custom Variant and Variant Library Synthesis for CNNM1

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

CNNM1 for disorders           About GeneDecksing

OMIM gene information: 607802    OMIM disorders: --

9 diseases for CNNM1:    About MalaCards

cone-rod dystrophy amelogenesis imperfecta urofacial syndrome alzheimer's disease

pneumonia tuberculosis malaria neuronitis

mycobacterium tuberculosis

2 diseases from the University of Copenhagen DISEASES database for CNNM1:

cone-rod dystrophy Amelogenesis imperfecta

Human Genome Epidemiology (HuGE) Navigator: CNNM1 (2 documents)

Export disorders for CNNM1 gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
About This Section

PubMed articles for CNNM1 gene, integrated from 9 sources (see all 12):
(articles sorted by number of sources associating them with CNNM1)

Utopia: connect your pdf to the dynamic
world of online information

Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)^{1, 2} Kimura K.... Sugano S. (2006)
Molecular cloning and characterization of a novel gene family of four ancient conserved domain proteins (ACDP). (PubMed id 12657465)^{1, 2} Wang C.-Y.... She J.-X. (2003)
A genome-wide scan of Ashkenazi Jewish Crohn's disease suggests novel susceptibility loci. (PubMed id 22412388)¹ Kenny E.E....Peter I. (2012)
Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)¹ Rose J.E....Uhl G.R. (2010)
The full-ORF clone resource of the German cDNA consortium. (PubMed id 17974005)² Bechtel S.... Schupp I. (2007)
A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease. (PubMed id 16385451)¹ Grupe A....Goate A. (2006)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)² Gerhard D.S....Malek J. (2004)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)¹ Ota T.... Sugano S. (2004)
The DNA sequence and comparative analysis of human chromosome 10. (PubMed id 15164054)² Deloukas P.... Rogers J. (2004)
Molecular cloning and characterization of the mouse Acdp gene family. (PubMed id 14723793)¹ Wang C.Y....She J.X. (2004)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section

		AND	OR
Aliases
Free Text

Query String		PubMed OMIM NCBI Bookshelf
	(Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 26507	HGNC: 102	AceView: CNNM1	Ensembl:ENSG00000119946	euGenes: HUgn26507
ECgene: CNNM1	H-InvDB: CNNM1

(According to HUGE)
About This Section

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for CNNM1	Pharmacogenomics, SNPs, Pathways

Intellectual Property for CNNM1 gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

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Patent Information for CNNM1 gene:
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(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
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GeneCards Homepage - Last full update: 19 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

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