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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

CNN2 Gene

protein-coding   GIFtS: 53
GCID: GC19P001026

calponin 2

 Explore 4 diseases affiliated with
CNN2 via our new
 Human Malady Compendium 
Biological research products
for CNN2
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Calponin 21 2
Calponin H2, Smooth Muscle2 3
Neutral Calponin2 3
Calponin-21

External Ids:    HGNC: 21561   Entrez Gene: 12652   Ensembl: ENSG000000646667   OMIM: 6023735   UniProtKB: Q994393   

Export aliases for CNN2 gene to outside databases

Previous GC identifers: GC19P001102 GC19P000966 GC19P000977 GC19P000799


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for CNN2:
The protein encoded by this gene, which can bind actin, calmodulin, troponin C, and tropomyosin, may function in the
structural organization of actin filaments. The encoded protein could play a role in smooth muscle contraction and
cell adhesion. Two transcript variants encoding different isoforms have been found for this gene. (provided by RefSeq,
Jul 2008)

UniProtKB/Swiss-Prot: CNN2_HUMAN, Q99439
Function: Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle
contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin
with actin inhibits the actomyosin Mg-ATPase activity




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000019.9  NC_018930.1  NT_011255.14  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the CNN2 gene promoter:
         Max1   NRSF form 1   Brachyury   NRSF form 2   AP-2gamma   COMP1   AP-2beta   AP-2alpha   c-Myc   AP-2alphaA   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): CNN2 promoter sequence
   Search SABiosciences Chromatin IP Primers for CNN2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CNN2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19p13.3   Ensembl cytogenetic band:  19p13.3   HGNC cytogenetic band: 19p13.3

CNN2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CNN2 gene location

GeneLoc information about chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19P001026:  view genomic region     (about GC identifiers)

Start:
1,026,212 bp from pter      End:
1,039,068 bp from pter
Size:
12,857 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: CNN2_HUMAN, Q99439 (See protein sequence)
Recommended Name: Calponin-2  
Size: 309 amino acids; 33697 Da
1 PDB 3D structure from and Proteopedia for CNN2:
1WYN (3D)    
Secondary accessions: A5D8U8 A6NFI4 D6W5X9 Q92578
Alternative splicing: 2 isoforms:  Q99439-1   Q99439-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for CNN2: NX_Q99439

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q99439

  • CNN2 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (2 alternative transcripts): 
    NP_004359.1  NP_958434.1  

    ENSEMBL proteins: 
     ENSP00000263097   ENSP00000455904   ENSP00000340129   ENSP00000457968   ENSP00000468577  
     ENSP00000456436   ENSP00000455777   ENSP00000457397   ENSP00000458137  

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    Novus Biologicals CNN2 Protein
    Novus Biologicals CNN2 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for CNN2

    Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001725stress fiber IDA16236705
    GO:0005856cytoskeleton TAS8889829
    GO:0005911cell-cell junction TAS8889829


    CNN2 for ontologies           About GeneDecksing



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    Uscn ELISAs and CLIAs for CNN2


    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    CNN2 for domains           About GeneDecksing

    4 InterPro domains/families:
     IPR001997 Calponin
     IPR001715 CH-domain
     IPR003096 SM22_calponin
     IPR000557 Calponin_repeat

    Graphical View of Domain Structure for InterPro Entry Q99439

    ProtoNet protein and cluster: Q99439

    3 Blocks protein families:
    IPB001715 Calponin-like actin-binding
    IPB001997 Calponin signature
    IPB003247 Calponin-like actin-binding subtype


    UniProtKB/Swiss-Prot: CNN2_HUMAN, Q99439
    Similarity: Belongs to the calponin family
    Similarity: Contains 3 calponin-like repeats
    Similarity: Contains 1 CH (calponin-homology) domain


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: CNN2_HUMAN, Q99439
    Function: Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle
    contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. The interaction of calponin
    with actin inhibits the actomyosin Mg-ATPase activity

         Genatlas biochemistry entry for CNN2:
    calponin neutral,h2,cytoskeletal protein of smooth muscle cells,actin,calmodulin,tropomyosin binding,closely related to
    non-muscle calponin CNN3

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    hsa-miR-137 hsa-miR-130a* hsa-miR-133b hsa-miR-23c hsa-miR-23b hsa-miR-133a hsa-miR-23a hsa-miR-143*
    SwitchGear 3'UTR luciferase reporter plasmidCNN2 3' UTR sequence
    Inhib. RNA
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CNN2

    Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003779actin binding IEA--
    GO:0005516calmodulin binding IEA--


    CNN2 for ontologies           About GeneDecksing


    1 GenomeRNAi human phenotype for CNN2:
     High actin ratio cells 

    Animal Models:
         Mouse knock-out Cnn2tm1.2Jin for CNN2
         5 MGI mutant phenotypes (inferred from 3 alleles(MGI details for Cnn2):
     cellular  hematopoietic system  homeostasis/metabolism  immune system  no phenotypic analysis 

    CNN2 for phenotypes           About GeneDecksing


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section

    Unified GeneCards pathways  About this table 
    See pathways by source

    Super-pathwaycontained gene-specific pathways
    1Calcium Regulation in the Cardiac Cell
    Myometrial Relaxation and Contraction Pathways0.43


    1 BioSystems Pathway for CNN2 
        Myometrial Relaxation and Contraction Pathways


    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CNN2

    STRING Interaction Network Preview (showing 3 interactants - click image to see more details)

    3 Interacting proteins for CNN2 (Q994393 ENSP000002630974) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    ACTBP607093, ENSP000003499604I2D: score=1 STRING: ENSP00000349960
    UBCENSP000003448184STRING: ENSP00000344818
    ELAVL1ENSP000003852694STRING: ENSP00000385269
    About this table

    Gene Ontology (GO): 5/10 biological process terms (GO ID links to tree view) (see all 10):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007010cytoskeleton organization TAS8889829
    GO:0010628positive regulation of gene expression IEA--
    GO:0030097hemopoiesis IEA--
    GO:0030336negative regulation of cell migration IEA--
    GO:0031032actomyosin structure organization IEA--


    CNN2 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for CNN2
    Search CenterWatch for drugs/clinical trials and news about CNN2 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for CNN2 gene (2 alternative transcripts): 
    NM_004368.2  NM_201277.1  

    Unigene Cluster for CNN2:

    Calponin 2
    Hs.651512  [show with all ESTs]
    Unigene Representative Sequence: NM_004368
    10 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000263097 ENST00000562015 ENST00000348419(uc002lqu.3 uc002lqv.3 uc010xgb.2 uc010xgc.2)
    ENST00000565096 ENST00000569352 ENST00000562958 ENST00000562075(uc002lqt.1 uc010drz.1)
    ENST00000566695 ENST00000568865 ENST00000564572

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    hsa-miR-137 hsa-miR-130a* hsa-miR-133b hsa-miR-23c hsa-miR-23b hsa-miR-133a hsa-miR-23a hsa-miR-143*
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    Inhib. RNA
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    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CNN2
    Clone
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    Additional cDNA sequence: 

    AK024835.1 AK057960.1 AK126391.1 AK222924.1 AK293171.1 AK295271.1 AK297774.1 AK300788.1 
    AY927510.1 AY927514.1 BC141818.1 BC141833.1 BC148264.1 CR541810.1 CR541831.1 D83735.1 
    D86059.1 

    24/42 DOTS entries (see all 42):

    DT.92452188  DT.100888912  DT.95372006  DT.100765294  DT.95332015  DT.95372004  DT.95071699  DT.100696096 
    DT.95371979  DT.100888937  DT.100888950  DT.100888951  DT.100766100  DT.121502280  DT.121502267  DT.121502259 
    DT.100696720  DT.95076658  DT.100753847  DT.100688095  DT.100841523  DT.100888919  DT.100888920  DT.95372005 

    21 AceView cDNA sequences:

    CR592852 CR598250 CR615042 CR618608 CR616871 CR603928 CR607371 CR602855 
    CR606476 CR611249 CR592088 CR541810 NM_004368 NM_201277 AK093630 AK024835 
    D83735 AK057960 CR541831 D86059 X05126 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for CNN2    About this scheme

    ExUns: 1 ^ 2a · 2b ^ 3 ^ 4a · 4b · 4c ^ 5 ^ 6 ^ 7a · 7b
    SP1:        -                             -                           
    SP2:        -                             -     -                     
    SP3:        -                       -     -                           
    SP4:                                      -                           
    SP5:        -                                                         


    ECgene alternative splicing isoforms for CNN2

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    CNN2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: CCCCGCCAAG

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    See CNN2 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for CNN2

    SOURCE GeneReport for Unigene cluster: Hs.651512

    UniProtKB/Swiss-Prot: CNN2_HUMAN, Q99439
    Tissue specificity: Heart and smooth muscle

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CNN2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for CNN2 gene from 5/18 species (see all 18)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    chicken
    (Gallus gallus)
    Aves CNN21 calponin 2 80.7(n)
    85.86(a)
      100216000  NM_001142256.1  NP_001135728.1 
    African clawed frog
    (Xenopus laevis)
    Amphibia cnn2-prov2 calponin 2 80.48(n)    BC046257.1 
    zebrafish
    (Danio rerio)
    Actinopterygii Dr.282352 Danio rerio cDNA clone MGC65794 IMAGE6791200, complete more 74.97(n)    BC059802.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta Chd646
    CG50236
    (see all 3)
    --
    37(a)
    35(a)
    (see all 3)
    possible ortholog
    possible ortholog
    (see all 3)
    3L(4114289-4122388)
    3R(15995158-16000597)
    worm
    (Caenorhabditis elegans)
    Secernentea cpn-16
    cpn-26
    (see all 4)
    CalPoNin family member (cpn-2)
    (see all 4)
    34(a)
    34(a)
    (see all 4)
    possible ortholog
    1 ↔ many
    (see all 4)
    I(8636114-8637955)
    II(337339-339248)


    ENSEMBL Gene Tree for CNN2 (if available)
    TreeFam Gene Tree for CNN2 (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for CNN2 gene
    TAGLN22  TAGLN2  CNN12  CNN32  TAGLN32  
    18/21 SIMAP similar genes for CNN2 using alignment to 10 protein entries:     CNN2_HUMAN (see all proteins) (see all similar genes):
    RHBG    NLN    SEC14L3    COQ5    RRM2B    RBMS2
    CNN3    CNN1    KIAA0101    MST132    RQCD1    PFKFB3
    TAGLN3    ACTR10    TAGLN2    DOCK8    DYNC2LI1    TAGLN

    CNN2 for paralogs           About GeneDecksing


    5/21 Pseudogenes.org Pseudogenes for CNN2 (see all 21)
    PGOHUM00000242544 PGOHUM00000262204 PGOHUM00000246798 PGOHUM00000248916 PGOHUM00000245068


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/431 NCBI SNPs in CNN2 are shown (see all 431    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 19 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs81040901,2
    C,F,A,H--802763(+) CATCCC/TAGGCA 1 -- int12Minor allele frequency- T:0.50NA 4
    rs25697921,2
    C--802843(-) TGCCTG/AGGATG 1 -- int11Minor allele frequency- A:0.00NA 2
    rs26371091,2
    C,A,--802856(-) CCTGAG/CCTGGA 1 -- int12Minor allele frequency- C:0.33WA CSA 3
    rs1811289111,2
    --1024316(+) AGCCCG/TGCCAC 2 -- us2k10--------
    rs2020531551,2
    --1024419(+) TGAAA-/CCCGCA 2 -- us2k10--------
    rs1427698881,2
    --1024474(+) TCTACA/GGTCCC 2 -- us2k10--------
    rs1449858291,2
    --1024477(+) ACGGTC/TCCAGC 2 -- us2k10--------
    rs1869843161,2
    --1024659(+) ATCACC/GAGGTC 2 -- us2k10--------
    rs1914668521,2
    --1024673(+) AGATCG/TAGACC 2 -- us2k10--------
    rs1834450871,2
    --1024731(+) TTAGCC/TGGGTG 2 -- us2k10--------

    HapMap Linkage Disequilibrium report for CNN2 (1026212 - 1039068 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 10 variations for CNN2
         7 CNVs: 102759 102758 73270 4066 2237 5065 30885
         3 Indels: 73269 26386 45821
    Human Gene Mutation Database (HGMD): CNN2

    SABiosciences Cancer Mutation PCR Assays
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    CNN2 for disorders           About GeneDecksing

    OMIM gene information: 602373    OMIM disorders: --

    4 diseases for CNN2:    About MalaCards
    actinic keratosis    keratosis    down syndrome    neuronitis


    Export disorders for CNN2 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for CNN2 gene, integrated from 9 sources (see all 27):
    (articles sorted by number of sources associating them with CNN2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Molecular cloning and characterization of human non-smooth muscle calponin. (PubMed id 8889829)1, 2, 3, 9 Masuda H....Takahashi K. (1996)
    2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    3. Exploring proteomes and analyzing protein processing by mass spectrometric identification of sorted N-terminal peptides. (PubMed id 12665801)1, 2 Gevaert K.... Vandekerckhove J. (2003)
    4. A unique downregulation of h2-calponin gene expression in Down syndrome: a possible attenuation mechanism for fetal survival by methylation at the CpG island in the trisomic chromosome 21. (PubMed id 9001224)1, 2 Kuromitsu J.... Hayashizaki Y. (1997)
    5. A census of human soluble protein complexes. (PubMed id 22939629)1 Havugimana P.C....Emili A. (2012)
    6. Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
    7. A high-throughput approach for measuring temporal chan ges in the interactome. (PubMed id 22863883)1 Kristensen A.R....Foster L.J. (2012)
    8. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
    9. A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
    10. Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 1265 HGNC: 2156 AceView: CNN2 Ensembl:ENSG00000064666 euGenes: HUgn1265
    ECgene: CNN2 H-InvDB: CNN2

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for CNN2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for CNN2 gene:
    Search GeneIP for patents involving CNN2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 19 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

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