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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

CNKSR2 Gene

protein-coding   GIFtS: 53
GCID: GC0XP021302

connector enhancer of kinase suppressor of Ras 2
 Explore 5 diseases affiliated with
CNKSR2 via
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 Human Malady Compendium 
Biological research products
for CNKSR2    

Aliases
for CNKSR2 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Connector Enhancer Of Kinase Suppressor Of Ras 21 2     CNK Homolog Protein 22 3
CNK21 2 3 5     MAGUIN2
KSR21 2 3     Connector Enhancer Of KSR22
KIAA09021 3 5     Membrane-Associated Guanylate Kinase-Interacting Protein2
Connector Enhancer Of KSR 22 3     

External Ids:    HGNC: 197011   Entrez Gene: 228662   Ensembl: ENSG000001499707   OMIM: 3007245   UniProtKB: Q8WXI23   

Export aliases for CNKSR2 gene to outside databases

Previous GC identifers: GC0XP020754 GC0XP021152 GC0XP019116


Summaries
for CNKSR2 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for CNKSR2:
This gene encodes a multidomain protein that functions as a scaffold protein to mediate the mitogen-activated protein
kinase pathways downstream from Ras. This gene product is induced by vitamin D and inhibits apoptosis in certain
cancer cells. It may also play a role in ternary complex assembly of synaptic proteins at the postsynaptic membrane
and coupling of signal transduction to membrane/cytoskeletal remodeling. Multiple transcript variants encoding
different isoforms have been found for this gene. (provided by RefSeq, Dec 2009)

UniProtKB/Swiss-Prot: CNKR2_HUMAN, Q8WXI2
Function: May function as an adapter protein or regulator of Ras signaling pathways

Gene Wiki entry for CNKSR2


Genomic Views
for CNKSR2 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000023.10  NC_018934.1  NT_167197.1  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the CNKSR2 gene promoter:
         Nkx3-1   Nkx3-1 v4   Pbx1a   Nkx3-1 v1   Cdc5   Nkx3-1 v2   FOXJ2 (long isoform)   Nkx3-1 v3   Sox9   FOXJ2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: CNKSR2 promoter sequence
   Search SABiosciences Chromatin IP Primers for CNKSR2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CNKSR2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: Xp22.12   Ensembl cytogenetic band:  Xp22.12   HGNC cytogenetic band: Xp22.12

CNKSR2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CNKSR2 gene location

GeneLoc information about chromosome X         GeneLoc Exon Structure

GeneLoc location for GC0XP021302:  view genomic region     (about GC identifiers)

Start:
 21,392,536 bp from pter      End:
 21,672,813 bp from pter
Size:
 280,278 bases      Orientation:
 plus strand

Proteins
for CNKSR2 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: CNKR2_HUMAN, Q8WXI2 (See protein sequence)
Recommended Name: Connector enhancer of kinase suppressor of ras 2  
Size: 1034 amino acids; 117535 Da
Subunit: Interacts with RAF1, RAB2L and RAL GTPase proteins
Subcellular location: Cytoplasm. Membrane; Peripheral membrane protein
2 PDB 3D structures from and Proteopedia for CNKSR2:
2EAN (3D)        3BS5 (3D)    
Secondary accessions: B4DGR4 B7ZLJ1 B9EG83 E7ESA4 O94976 Q5JPK4 Q5JPN0 Q8WXI1
Alternative splicing: 4 isoforms:  Q8WXI2-1   Q8WXI2-2   Q8WXI2-4   Q8WXI2-5   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for CNKSR2: NX_Q8WXI2

Post-translational modifications:

  • Phosphorylated on tyrosine1
  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q8WXI2

    • CNKSR2 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (4 alternative transcripts): 
    NP_001162118.1  NP_001162119.1  NP_001162120.1  NP_055742.2  

    ENSEMBL proteins: 
     ENSP00000279451   ENSP00000368824   ENSP00000397906   ENSP00000444633  

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    Uscn Proteins for CNKSR2

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005737cytoplasm IEA--
    GO:0043005neuron projection IEA--
    GO:0043025neuronal cell body IEA--
    GO:0045211postsynaptic membrane IEA--


    CNKSR2 for ontologies           About GeneDecksing



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    Protein Domains /
    Families
    for CNKSR2 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    CNKSR2 for domains           About GeneDecksing

    5/9 InterPro domains/families (see all 9):
     IPR010599 CNKSR2
     IPR021129 SAM_type1
     IPR001849 Pleckstrin_homology
     IPR011993 PH_like_dom
     IPR013761 SAM/pointed

    Graphical View of Domain Structure for InterPro Entry Q8WXI2

    ProtoNet protein and cluster: Q8WXI2

    4 Blocks protein families:
    IPB001478 PDZ/DHR/GLGF domain
    IPB001660 Sterile alpha motif SAM
    IPB001849 Pleckstrin-like
    IPB010599 Protein of unknown function DUF1170


    UniProtKB/Swiss-Prot: CNKR2_HUMAN, Q8WXI2
    Similarity: Belongs to the CNKSR family
    Similarity: Contains 1 CRIC domain
    Similarity: Contains 1 DUF1170 domain
    Similarity: Contains 1 PDZ (DHR) domain
    Similarity: Contains 1 PH domain
    Similarity: Contains 1 SAM (sterile alpha motif) domain


    Function
    for CNKSR2 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    Function Summary:

         UniProtKB/Swiss-Prot: CNKR2_HUMAN, Q8WXI2
    Function: May function as an adapter protein or regulator of Ras signaling pathways

    miRNA
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    hsa-miR-3164 hsa-miR-15a hsa-miR-1260b hsa-let-7a-2* hsa-miR-30d hsa-miR-507 hsa-miR-424 hsa-miR-30a
    SwitchGear 3'UTR luciferase reporter plasmid: CNKSR2 3' UTR sequence
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CNKSR2 (see all 6)
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    Gene Editing
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    Clone
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    In Situ Assay
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    Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
    GO:0005543phospholipid binding IEA--


    CNKSR2 for ontologies           About GeneDecksing



    Pathways & Interactions
    for CNKSR2 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CNKSR2

    STRING Interaction Network Preview (showing 5 interactants - click image to see 17)

    5/26 Interacting proteins for CNKSR2 (Q8WXI22, 3 ENSP000003688244) via UniProtKB, MINT, STRING, and/or I2D (see all 26)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    LRRC7Q96NW72, 3, ENSP000000353834MINT-1784595 I2D: score=4 STRING: ENSP00000035383
    DLG4P783523, ENSP000002938134I2D: score=2 STRING: ENSP00000293813
    MOB3BQ86TA13, ENSP000002622444I2D: score=2 STRING: ENSP00000262244
    TNIKQ9UKE53, ENSP000003995114I2D: score=2 STRING: ENSP00000399511
    CDK2P249413, ENSP000002669704I2D: score=1 STRING: ENSP00000266970
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0009966regulation of signal transduction IEA--


    CNKSR2 for ontologies           About GeneDecksing



    Drugs & Compounds
    for CNKSR2 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for CNKSR2
    Search CenterWatch for drugs/clinical trials and news about CNKSR2 / CNKR2 

    Transcripts
    for CNKSR2 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for CNKSR2 gene (4 alternative transcripts): 
    NM_001168647.1  NM_001168648.1  NM_001168649.1  NM_014927.3  

    Unigene Cluster for CNKSR2:

    Connector enhancer of kinase suppressor of Ras 2
    Hs.555917  [show with all ESTs]
    Unigene Representative Sequence: NM_014927
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000279451(uc004czw.3) ENST00000379510 ENST00000480138 ENST00000479158
    ENST00000485012 ENST00000425654(uc004czx.2 uc011mjo.2) ENST00000543067(uc011mjn.2 uc004czy.3)


    miRNA
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    8/52 QIAGEN miScript miRNA Assays for microRNAs that regulate CNKSR2 (see all 52):
    hsa-miR-3164 hsa-miR-15a hsa-miR-1260b hsa-let-7a-2* hsa-miR-30d hsa-miR-507 hsa-miR-424 hsa-miR-30a
    SwitchGear 3'UTR luciferase reporter plasmid: CNKSR2 3' UTR sequence
    Inhib. RNA
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    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CNKSR2 (see all 6)
    OriGene siRNA: CNKSR2
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CNKSR2
    Clone
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    Primer
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    Additional cDNA sequence: 

    AB020709.1 AF418269.1 AF418270.1 AK056549.1 AK124258.1 AK294728.1 BC092447.1 BC126121.1 
    BC136289.1 BC143839.1 

    6 DOTS entries:

    DT.408062  DT.210699  DT.95153379  DT.100736664  DT.121288814  DT.427299 

    24/57 AceView cDNA sequences (see all 57):

    AK056549 AA325920 NM_014927 AF418270 BM692904 AI361550 AA081786 AB020709 
    AF418269 AW468132 CA975859 F09543 BP348863 BI489493 AI670947 BE670298 
    BG611098 BF446568 BF432843 AW237040 AW896402 F11896 BE702076 BF115709 

    GeneLoc Exon Structure

    4 Alternative Splicing Database (ASD) splice patterns (SP) for CNKSR2    About this scheme

    ExUns: 1a · 1b ^ 2a · 2b ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14 ^ 15 ^ 16 ^ 17 ^ 18 ^ 19 ^ 20 ^ 21 ^ 22
    SP1:                                                                                                                                                
    SP2:                                                                                -                                                               
    SP3:                                                                                                                                                
    SP4:        -                                                                                                                                       


    ECgene alternative splicing isoforms for CNKSR2

    Expression
    for CNKSR2 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    CNKSR2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: AAAGAGACCT

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    CNKSR2 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    Stem Cell Differentiation: 1 LifeMap Cell 
    NameCategory
    Primitive gut tube-like cells (A scalable, suspensi...)
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization

    See CNKSR2 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for CNKSR2

    SOURCE GeneReport for Unigene cluster: Hs.555917
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    In Situ
    Assay Products:     
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    Orthologs
    for CNKSR2 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of animals.

    Orthologs for CNKSR2 gene from 6/16 species (see all 16)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    mouse
    (Mus musculus)    		 Mammalia Cnksr21 , 5 connector enhancer of kinase suppressor of Ras 21, 5 93.8(n)1
    98.84(a)1    		   X (72.76 cM)5
    2456841  NM_177751.21  NP_808419.11 
     1578214365 
    chicken
    (Gallus gallus)    		 Aves CNKSR21 connector enhancer of kinase suppressor of Ras 2 81.88(n)
    90.43(a)    		   427997  XM_425567.3  XP_425567.3 
    lizard
    (Anolis carolinensis)    		 Reptilia CNKSR26
    --
    		 --
    		 92(a)
    77(a)
    		 1 ↔ 1
    possible ortholog
    		 3(124332862-124448860)
    3(124455303-124493337)
    zebrafish
    (Danio rerio)    		 Actinopterygii Dr.262982 Transcribed sequence with weak similarity to protein more 76.55(n)    CD604333.1 
    fruit fly
    (Drosophila melanogaster)    		 Insecta cnk6
    		 connector enhancer of ksr
    		 14(a)
    		 possible ortholog
    		 2R(13301476-13307104)
    worm
    (Caenorhabditis elegans)    		 Secernentea cnk-16
    		 Connector/eNhancer of KSR family member (cnk-1)
    		 19(a)
    		 possible ortholog
    		 III(10271166-10278488)


    ENSEMBL Gene Tree for CNKSR2 (if available)
    TreeFam Gene Tree for CNKSR2 (if available) 

    Paralogs
    for CNKSR2 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for CNKSR2 gene
    IPCEF12  CNKSR12  CNKSR32  
    2 SIMAP similar genes for CNKSR2 using alignment to 2 protein entries:     CNKR2_HUMAN (see all proteins):
    CNKSR3    IPCEF1

    CNKSR2 for paralogs           About GeneDecksing



    Genomic Variants
    for CNKSR2 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/2503 NCBI SNPs in CNKSR2 are shown (see all 2503)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr X posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs2007170351,2
    		--21390581(+) TACAC-/ATATATA 4 -- us2k10--------
    rs1905475261,2
    		--21390630(+) ACACAC/TATATA 4 -- us2k10--------
    rs1838728141,2
    		--21390841(+) ACACAC/TATATA 4 -- us2k10--------
    rs1889703501,2
    		--21390865(+) ACACAC/TATATA 4 -- us2k10--------
    rs1926811851,2
    		--21391236(+) GTCACA/TATATT 4 -- us2k10--------
    rs1844810941,2
    		C,--21391280(+) GTGTGG/TGGGGG 4 -- us2k10--------
    rs1870734681,2
    		--21391296(+) GGTGTC/TGTCAA 4 -- us2k10--------
    rs1392194611,2
    		--21391332(+) TTTCTC/GCATCT 4 -- us2k10--------
    rs59514451,2
    		C,F,H,--21391485(+) GAGTTA/TGCATC 4 -- us2k18Minor allele frequency- T:0.43NS EA NA WA CSA 425
    rs1916742601,2
    		--21391822(+) CGCCTG/TACTTC 4 -- us2k10--------

    HapMap Linkage Disequilibrium report for CNKSR2 (21392536 - 21642536 bp, first 250kb of CNKSR2)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 4 variations for CNKSR2
         2 CNVs: 83409 96545
         2 Indels: 96546 96547
    Human Gene Mutation Database (HGMD): CNKSR2

    Locus Specific Mutation Databases (LSDB): CNKSR2

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    Disorders / Diseases
    for CNKSR2 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    CNKSR2 for disorders           About GeneDecksing

    OMIM gene information: 300724    OMIM disorders: --

    5 diseases for CNKSR2:    About MalaCards
    mastitis    neuritis    schizophrenia    leukemia
    neuronitis


    Export disorders for CNKSR2 gene to outside databases

    Publications
    for CNKSR2 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for CNKSR2 gene, integrated from 9 sources (see all 25):
    (articles sorted by number of sources associating them with CNKSR2)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. The DNA sequence of the human X chromosome. (PubMed id 15772651)1, 2 Ross M.T.... Bentley D.R. (2005)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    4. Human homologue of Drosophila CNK interacts with Ras effector proteins Raf and Rlf. (PubMed id 14597674)1, 2 Lanigan T.M.... Guan K.-L. (2003)
    5. Prediction of the coding sequences of unidentified human genes. XII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 10048485)1, 2 Nagase T....Ohara O. (1998)
    6. System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)2 Rigbolt K.T....Blagoev B. (2011)
    7. Genome-wide association study of biochemical traits in Korcula Island, Croatia. (PubMed id 19260141)1 Zemunik T....Rudan I. (2009)
    8. Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. (PubMed id 19690332)2 Mayya V.... Han D.K. (2009)
    9. Defining the human deubiquitinating enzyme interactio n landscape. (PubMed id 19615732)1 Sowa M.E....Harper J.W. (2009)
    10. Proteomic characterization of the dynamic KSR-2 inter actome, a signaling scaffold complex in MAPK pathway. (PubMed id 19563921)1 Liu L....Qiu Y. (2009)

    External Searches for CNKSR2 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
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      Query String
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    OMIM
    NCBI Bookshelf
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    Genome Databases showing CNKSR2 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 22866 HGNC: 19701 AceView: CNKSR2 Ensembl:ENSG00000149970 euGenes: HUgn22866
    ECgene: CNKSR2 H-InvDB: CNKSR2

    Other Databases showing CNKSR2 gene

    (According to HUGE)
    About This Section
    HUGE: KIAA0902

    Specialized Databases showing CNKSR2 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for CNKSR2 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for CNKSR2 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for CNKSR2 gene:
    Search GeneIP for patents involving CNKSR2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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