CNKSR1 Gene
protein-coding GIFtS: 52
GCID: GC01P026503
|
|
connector enhancer of kinase suppressor of Ras 1
| |
Aliases for CNKSR1 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb) About This Section
| This gene clusters with an RNA gene Subcategory (RNA class): lncRNA
Quality score for the ORGUL clustered with this gene is 3
| Aliases |
|---|
| Connector Enhancer Of Kinase Suppressor Of Ras 11 2 | | Connector Enhancer Of KSR 12 3 | | CNK11 2 3 | | CNK Homolog Protein 12 3 | | CNK1 2 | | HCNK11 | | KSR1 2 | | Connector Enhancer Of KSR-Like3 |
| External Ids: | HGNC: 197001 | Entrez Gene: 102562 | Ensembl: ENSG000001426757 | OMIM: 6032725 | UniProtKB: Q969H43 |
|---|
| | ORGUL members: | |
|---|
| NONCODE:n406454 | |
Export aliases for CNKSR1 gene to outside databasesPrevious GC identifers: GC01P026109 GC01P026188 GC01P026376 GC01P024758
Summaries for CNKSR1 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| Entrez Gene summary for CNKSR1: This gene is a necessary element in receptor tyrosine kinase pathways, possibly as a tyrosine phosphorylation target.It is involved in regulation of RAF in the MAPK pathway and may also play a role in a MAPK-independent pathway.(provided by RefSeq, Jul 2008) UniProtKB/Swiss-Prot: CNKR1_HUMAN, Q969H4Function: May function as an adapter protein or regulator of Ras signaling pathways Gene Wiki entry for CNKSR1
|
Genomic Views for CNKSR1 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics) About This Section
| RefSeq DNA sequence:- NC_000001.10 NC_018912.1 NT_004610.19
Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the CNKSR1 gene promoter: HEN1 AP-1 ATF-2 c-Jun ATF Other transcription factors
Search SABiosciences Chromatin IP Primers for CNKSR1
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CNKSR1 |
Genomic Location: Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 1p36.11 Ensembl cytogenetic band: 1p36.11 HGNC cytogenetic band: 1p35.3CNKSR1 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)

GeneLoc information about chromosome 1 GeneLoc Exon Structure GeneLoc location for GC01P026503: view genomic region
(about GC identifiers)
Start:
|
26,503,894 bp from pter |
End:
|
26,516,377 bp from pter |
Size:
|
12,484 bases |
Orientation:
|
plus strand |
|
Proteins for CNKSR1 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
| UniProtKB/Swiss-Prot: CNKR1_HUMAN, Q969H4 (See
protein sequence)Recommended Name: Connector enhancer of kinase suppressor of ras 1 Size: 720 amino acids; 79706 Da
Subunit: Interacts with RHO and RALGDS
Subcellular location: Cytoplasm (By similarity). Membrane; Peripheral membrane protein (By similarity)
1 PDB 3D structure from and Proteopedia for CNKSR1:1WWV (3D)
 
Secondary accessions: B1AMW9 O95381Alternative splicing: 2 isoforms: Q969H4-1 Q969H4-2 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for CNKSR1: NX_Q969H4
Post-translational modifications:
Phosphorylated on tyrosine1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q969H4 CNKSR1 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_006305.2 ENSEMBL proteins: ENSP00000354609 ENSP00000432057 ENSP00000363371 ENSP00000437038 ENSP00000435880 ENSP00000431817 ENSP00000434047 Human Recombinant Protein Products:
Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table
CNKSR1 for ontologies About GeneDecksing
CNKSR1 Antibody Products: Assay Products for CNKSR1: |
Protein
Domains / Families for CNKSR1 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
CNKSR1 for domains About GeneDecksing
5/8 InterPro domains/families (see all 8):Graphical View of Domain Structure for InterPro Entry Q969H4ProtoNet protein and cluster: Q969H4 3 Blocks protein families: IPB001660 Sterile alpha motif SAM IPB001849 Pleckstrin-like IPB011510 Sterile alpha motif homology 2
UniProtKB/Swiss-Prot: CNKR1_HUMAN, Q969H4Similarity: Belongs to the CNKSR familySimilarity: Contains 1 CRIC domainSimilarity: Contains 1 PDZ (DHR) domainSimilarity: Contains 1 PH domainSimilarity: Contains 1 SAM (sterile alpha motif) domain |
Function for CNKSR1 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
| Function Summary: UniProtKB/Swiss-Prot: CNKR1_HUMAN, Q969H4Function: May function as an adapter protein or regulator of Ras signaling pathways
Clone Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CNKSR1 (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CNKSR1 (see all 2) OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: CNKSR1 (NM_006314) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CNKSR1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CNKSR1  |
In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CNKSR1 |
Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view): About this table
CNKSR1 for ontologies About GeneDecksing
1 GenomeRNAi human phenotype for CNKSR1:
|
Pathways & Interactions for CNKSR1 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for CNKSR1
STRING Interaction
Network Preview (showing 5 interactants - click image to see 20)
 5/22 Interacting proteins for CNKSR1 (Q969H41, 2, 3 ENSP000003546094) via UniProtKB, MINT, STRING, and/or I2D (see all 22)| Interactant | Interaction Details |
|---|
| GeneCard | External ID(s) |
|---|
| RHOA | P615861, 2, 3, ENSP000004001754 | EBI-741671,EBI-446668 MINT-56522 MINT-56518 MINT-56516 MINT-56519 I2D:
score=5 STRING: ENSP00000400175 | | CYTH3 | O437392, 3, ENSP000002970444 | MINT-66188 I2D:
score=5 STRING: ENSP00000297044 | | SMAD4 | Q134852, 3 | MINT-61978 I2D:
score=3 | | RAF1 | P040492, 3, ENSP000002518494 | MINT-56513 I2D:
score=4 STRING: ENSP00000251849 | | RASSF1 | Q9NS232, 3, ENSP000003495474 | MINT-56515 I2D:
score=4 STRING: ENSP00000349547 | About this table
Gene Ontology (GO): 3 biological process terms (GO ID links to tree view): About this table
CNKSR1 for ontologies About GeneDecksing
|
Drugs & Compounds for CNKSR1 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
CNKSR1 for compounds About GeneDecksing
Browse Tocris compounds for CNKSR1 3 Novoseek chemical compound relationships for CNKSR1 gene About this table
| Compound |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| ceramide |
63.7 |
4 |
9531568 (1), 9804808 (1), 12676512 (1) |
| threonine |
24.3 |
1 |
11134016 (1) |
| tyrosine |
21.1 |
1 |
8521512 (1) |
Search CenterWatch for drugs/clinical trials and news about CNKSR1 / CNKR1 
|
Transcripts for CNKSR1 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
) About This Section
| REFSEQ mRNAs for CNKSR1 gene: NM_006314.2 Unigene Cluster for CNKSR1: Connector enhancer of kinase suppressor of Ras 1 Hs.16232 [show with all ESTs]Unigene Representative Sequence: BC01279714 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000361530(uc010oex.1 uc001blm.4 uc009vsd.3 uc009vse.3) ENST00000481077 ENST00000480348 ENST00000465415 ENST00000374253(uc001bln.4) ENST00000525687 ENST00000482227 ENST00000531191 ENST00000524529 ENST00000531150 ENST00000528001 ENST00000528281 ENST00000480617 ENST00000484874
Clone Products: |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CNKSR1 (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CNKSR1 (see all 2) OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: CNKSR1 (NM_006314) | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CNKSR1 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CNKSR1  |
Additional cDNA sequence: AB209335.1 AF100153.1 AK001900.1 AK222817.1 AK222904.1 AK292646.1 AK296814.1 AK302056.1 BC011604.2 BC012797.2 BT006900.1 NR_023345.1 10 DOTS entries: DT.412818 DT.95269681 DT.95069868 DT.100806032 DT.100721147 DT.100778809 DT.121348186 DT.100683003 DT.121348185 DT.99975514 24/99 AceView cDNA sequences (see all 99): BM750903 BE730887 AW961213 T24751 NM_006314 BI916418 CB854293 CA433801 BU685413 CK824807 AF100153 BX363940 BT006900 BE140561 BG479915 BC011604 BU944084 BX280341 BC012797 AW299295 BM918431 CR624234 R48382 BM271803 GeneLoc Exon Structure
5/9 Alternative Splicing Database (ASD) splice patterns (SP) for CNKSR1 (see all 9) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | ^ | 2a | · | 2b | ^ | 3a | · | 3b | ^ | 4a | · | 4b | ^ | 5 | ^ | 6 | ^ | 7a | · | 7b | ^ | 8a | · | 8b | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13 | ^ | 14 | ^ | 15a | · | 15b | ^ | 16 | ^ | 17a | · | |
| SP1: | |   | |   | |   | |   | - |   | |   | |   | - |   | - |   | |   | |   | |   | |   | |   | |   | - |   | |   | |   | |   | |   | |   | |   | - |   | |   | |   | |   | |
| SP2: | |   | |   | |   | |   | - |   | |   | |   | - |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | - |   | |   | |   | |   | |
| SP3: | |   | |   | |   | |   | - |   | |   | |   | - |   | - |   | |   | |   | |   | |   | |   | |   | - |   | |   | |   | |   | |   | |   | |   | - |   | |   | |   | |   | |
| SP4: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | - |   | |   | - |   | |   | |   | |   | |   | - |   | |   | |   | |   | |
| SP5: | |   | |   | |   | - |   | - |   | |   | |   | - |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   | |   |
| ExUns: | 17b | ^ | 18 | ^ | 19 | ^ | 20 | ^ | 21 | |
| SP1: | |   | |   | |   | |   | |   | |
| SP2: | |   | |   | |   | |   | |   | |
| SP3: | |   | |   | |   | |   | |   | |
| SP4: | |   | |   | |   | |   | |   | |
| SP5: | |   | |   | |   | |   | |   |
ECgene alternative splicing isoforms for CNKSR1
|
Expression for CNKSR1 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| CNKSR1 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this imageBioGPS CGAP TAG: AGGGCTACTT
About this image See CNKSR1 Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for CNKSR1
SOURCE GeneReport for Unigene cluster: Hs.16232 SABiosciences Custom PCR Arrays for CNKSR1
Primer Products: |  | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CNKSR1 Browse OriGene validated miRNA SYBR primer pairs
| |  | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat CNKSR1 | |  | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CNKSR1 | |  | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CNKSR1 | In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CNKSR1 |
Orthologs for CNKSR1 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of animals.
Orthologs for CNKSR1 gene from 5/17 species (see all 17) About this table
| Organism |
Taxonomic classification |
Gene |
Description |
Human Similarity |
Orthology Type |
Details |
chicken (Gallus gallus) |
Aves |
CNKSR11 |
connector enhancer of kinase suppressor of Ras 1 |
58.28(n) 50.15(a) |
  |
419548 XM_417698.3 XP_417698.3 |
lizard (Anolis carolinensis) |
Reptilia |
CNKSR16 |
-- |
43(a) |
1 ↔ 1 |
GL343480.1(390850-423416) |
zebrafish (Danio rerio) |
Actinopterygii |
cnksr11 |
connector enhancer of kinase suppressor of Ras 1 |
52.34(n) 40.83(a) |
  |
402957 NM_205659.1 NP_991222.1 |
fruit fly (Drosophila melanogaster) |
Insecta |
cnk6 |
connector enhancer of ksr |
9(a) |
possible ortholog |
2R(13301476-13307104) |
worm (Caenorhabditis elegans) |
Secernentea |
cnk-16 |
Connector/eNhancer of KSR family member (cnk-1) |
13(a) |
possible ortholog |
III(10271166-10278488) |
ENSEMBL Gene Tree for CNKSR1 (if available) TreeFam Gene Tree for CNKSR1 (if available)  |
Paralogs for CNKSR1 gene(Paralogs according to
1HomoloGene, 2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68) About This Section
| Paralogs for CNKSR1 gene
- IPCEF12 CNKSR32 CNKSR22
1 SIMAP similar gene for CNKSR1 using alignment to 7 protein entries: CNKR1_HUMAN (see all proteins):CNKSR3
CNKSR1 for paralogs About GeneDecksing
|
Genomic Variants for CNKSR1 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical significance | Chr 1 pos | Sequence | # | AA Chg | Type | More | # | Allele freq | Pop | Total sample | More |
|---|
HapMap Linkage Disequilibrium report for CNKSR1 (26503894 - 26516377 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV) variations for CNKSR1: -- Human Gene Mutation Database (HGMD): CNKSR1
 | SABiosciences Cancer Mutation PCR Assays |
|  | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CNKSR1 |
|
Disorders
/ Diseases for CNKSR1 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
CNKSR1 for disorders About GeneDecksing
OMIM gene information: 603272
OMIM disorders: --
3 diseases for CNKSR1: About MalaCardsendometriosis tuberculosis mycobacterium tuberculosis Export disorders for CNKSR1 gene to outside databases
|
Publications for CNKSR1 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for CNKSR1 gene, integrated from 9 sources (see all 42): (articles sorted by number of sources associating them with CNKSR1) | |  | Utopia: connect your pdf to the dynamic world of online information |
- CNK, a RAF-binding multidomain protein required for RAS signaling. (PubMed id 9814705)1, 2, 3, 9 Therrien M.... Rubin G.M. (1998)
- Human CNK1 acts as a scaffold protein, linking Rho and Ras signal transduction pathways. (PubMed id 14749388)1, 2, 9 Jaffe A.B.... Hall A. (2004)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Association of CNK1 with Rho guanine nucleotide exchange factors controls signaling specificity downstream of Rho. (PubMed id 15753034)1, 9 Jaffe A.B....Schmidt A. (2005)
- Bioluminescence resonance energy transfer identify scaffold protein CNK1 interactions in intact cells. (PubMed id 15670823)1, 9 Lopez-Ilasaca M.A....Xavier R.J. (2005)
- Carbohydrate-specific signaling through the DC-SIGN s ignalosome tailors immunity to Mycobacterium tuberculosis, HIV-1 and Helicobact er pylori. (PubMed id 19718030)1, 9 Gringhuis S.I....Geijtenbeek T.B. (2009)
- CNK1 and other scaffolds for Akt/FoxO signaling. (PubMed id 21320536)1 Fritz R.D. and Radziwill G. (2011)
- System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation. (PubMed id 21406692)2 Rigbolt K.T....Blagoev B. (2011)
- CNK1 promotes invasion of cancer cells through NF-kap paB-dependent signaling. (PubMed id 20197385)1 Fritz R.D. and Radziwill G. (2010)
- CNK1 is a novel Akt interaction partner that promotes cell proliferation through the Akt-FoxO signalling axis. (PubMed id 20383191)1 Fritz R.D....Radziwill G. (2010)
|
External Searches for CNKSR1 gene
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
|
|
Genome Databases showing CNKSR1 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing CNKSR1 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing CNKSR1 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
| Name | Description |
| PharmGKB entry for CNKSR1 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for CNKSR1 gene: Search GeneIP for patents involving CNKSR1
GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products for CNKSR1 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences), In Situ Hybridization Assays from Advanced Cell Diagnostics About This Section
|
 | |
 | |
 |
| | | | OriGene Antibodies for CNKSR1 | | OriGene shRNA RFP for CNKSR1 | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CNKSR1 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CNKSR1 | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | OriGene siRNA for CNKSR1 | | OriGene 3'-UTR Clone for CNKSR1 | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CNKSR1 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CNKSR1 | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | OriGene Custom Antibody Services for CNKSR1 | | OriGene Custom Protein Services for CNKSR1 | | OriGene Custom Immunoassay Development | | |
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| | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat CNKSR1 | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CNKSR1 | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CNKSR1 | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CNKSR1 | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CNKSR1 | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CNKSR1 |
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| | | Search Tocris compounds for CNKSR1 |
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| | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CNKSR1 |
|  |  |  | | | Search ThermoFisher Antibodies for CNKSR1 |
| | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CNKSR1 |
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Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013
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