Aliases for CNKSR1 Gene
External Ids for CNKSR1 Gene
Previous GeneCards Identifiers for CNKSR1 Gene
This gene encodes a protein containing several motifs involved in protein-protein interaction, including PDZ, PH (Pleckstrin homology), and SAM (sterile alpha motif) domains. The encoded protein acts as a scaffold component for receptor tyrosine kinase signaling and may mediate crosstalk between different signaling pathways. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
GeneCards Summary for CNKSR1 Gene
CNKSR1 (Connector Enhancer Of Kinase Suppressor Of Ras 1) is a Protein Coding gene. Among its related pathways are Interleukin-3, 5 and GM-CSF signaling and Signaling by GPCR. GO annotations related to this gene include kinase activity and protein binding, bridging. An important paralog of this gene is CNKSR2.
UniProtKB/Swiss-Prot for CNKSR1 Gene
May function as an adapter protein or regulator of Ras signaling pathways.