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CNIH3 Gene

protein-coding   GIFtS: 42
GCID: GC01P224622

Cornichon Family AMPA Receptor Auxiliary Protein 3

(Previous name: cornichon homolog 3 (Drosophila))
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Cornichon Family AMPA Receptor Auxiliary Protein 31 2 3
CNIH-32 3
Cornichon Homolog 3 (Drosophila)1
Cornichon Homolog 32
Protein Cornichon Homolog 32

External Ids:    HGNC: 268021   Entrez Gene: 1491112   Ensembl: ENSG000001437867   UniProtKB: Q8TBE13   

Export aliases for CNIH3 gene to outside databases

Previous GC identifers: GC01P221111 GC01P222870 GC01P195324


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for CNIH3 Gene:
CNIH3 (cornichon family AMPA receptor auxiliary protein 3) is a protein-coding gene. GO annotations related to this gene include channel regulator activity. An important paralog of this gene is CNIH1.

UniProtKB/Swiss-Prot: CNIH3_HUMAN, Q8TBE1
Function: Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes
their targeting to the cell membrane and synapses and modulates their gating properties by regulating their rates
of activation, deactivation and desensitization




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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Regulatory elements:
   Regulatory transcription factor binding sites in the CNIH3 gene promoter:
         NF-AT   NF-AT4   NF-AT2   HSF2   FOXO4   FOXJ2 (long isoform)   NF-AT3   FOXJ2   NF-AT1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCNIH3 promoter sequence
   Search Chromatin IP Primers for CNIH3

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat CNIH3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1q42.12   Ensembl cytogenetic band:  1q42.12   HGNC cytogenetic band: 1q42.12

CNIH3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CNIH3 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01P224622:  view genomic region     (about GC identifiers)

Start:
224,622,362 bp from pter      End:
224,928,251 bp from pter
Size:
305,890 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: CNIH3_HUMAN, Q8TBE1 (See protein sequence)
Recommended Name: Protein cornichon homolog 3  
Size: 160 amino acids; 18976 Da
Subunit: Acts as an auxiliary subunit for AMPA-selective glutamate receptors (AMPARs). Found in a complex with
GRIA1, GRIA2, GRIA3, GRIA4, CNIH2, CACNG2, CACNG3, CACNG4, CACNG5, CACNG7 and CACNG8 (By similarity)

Explore the universe of human proteins at neXtProt for CNIH3: NX_Q8TBE1

Explore proteomics data for CNIH3 at MOPED


See CNIH3 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

REFSEQ proteins: NP_689708.1  
ENSEMBL proteins: 
 ENSP00000272133  

CNIH3 Human Recombinant Protein Products:

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(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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1 InterPro protein domain:
 IPR003377 Cornichon

Graphical View of Domain Structure for InterPro Entry Q8TBE1

ProtoNet protein and cluster: Q8TBE1

1 Blocks protein domain: IPB003377 Cornichon

UniProtKB/Swiss-Prot: CNIH3_HUMAN, Q8TBE1
Similarity: Belongs to the cornichon family


Find genes that share domains with CNIH3           About GenesLikeMe


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Molecular Function:

     UniProtKB/Swiss-Prot Summary: CNIH3_HUMAN, Q8TBE1
Function: Regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). Promotes
their targeting to the cell membrane and synapses and modulates their gating properties by regulating their rates
of activation, deactivation and desensitization

     Gene Ontology (GO): 1 molecular function term:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0016247channel regulator activity IEA--
     
Find genes that share ontologies with CNIH3           About GenesLikeMe


Phenotypes:
     2 MGI mutant phenotypes (inferred from 1 allele(MGI details for Cnih3):
 nervous system  normal 

Find genes that share phenotypes with CNIH3           About GenesLikeMe

Animal Models:
   inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for CNIH3
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miRNA
Products:
    
miRTarBase miRNAs that target CNIH3:
hsa-mir-335-5p (MIRT017447)

Block miRNA regulation of human, mouse, rat CNIH3 using miScript Target Protectors
Selected qRT-PCR Assays for microRNAs that regulate CNIH3 (see all 16):
hsa-miR-21* hsa-miR-4289 hsa-miR-1226 hsa-miR-513a-5p hsa-miR-2110 hsa-miR-4312 hsa-miR-15a hsa-miR-497
SwitchGear 3'UTR luciferase reporter plasmidCNIH3 3' UTR sequence
Inhib. RNA
Products:
    
OriGene RNAi products in human, mouse, rat for CNIH3
Predesigned siRNA for gene silencing in human, mouse, rat CNIH3

Gene Editing
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OriGene ORF clones in mouse, rat for CNIH3
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector: CNIH3 (NM_152495)
Sino Biological Human cDNA Clone for CNIH3
DNA2.0 Custom Codon Optimized Gene Synthesis Service for CNIH3
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CNIH3

Cell Line
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In Situ Assay
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Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CNIH3


(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Subcellular locations from UniProtKB/Swiss-Prot
CNIH3_HUMAN, Q8TBE1: Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein (By
similarity). Note=Also localizes to the cell membrane of extrasynaptic sites (dendritic shafts, spines of
pyramidal cells) (By similarity)
Subcellular locations from COMPARTMENTS: 

CompartmentConfidence
plasma membrane4
extracellular3

Gene Ontology (GO): 5 cellular component terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0016020membrane ----
GO:0030054cell junction IEA--
GO:0032281alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid selective glutamate receptor complex ISS--
GO:0043198dendritic shaft ISS--
GO:0045211postsynaptic membrane ISS--

Find genes that share ontologies with CNIH3           About GenesLikeMe


(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for CNIH3
Interactions:

    Search GeneGlobe Interaction Network for CNIH3

STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

Selected Interacting proteins for CNIH3 (ENSP000002721334) via UniProtKB, MINT, STRING, and/or I2D (see all 32)
InteractantInteraction Details
GeneCardExternal ID(s)
CACNG3ENSP000000052844STRING: ENSP00000005284
CACNG4ENSP000002621384STRING: ENSP00000262138
CACNG5ENSP000001695654STRING: ENSP00000169565
CACNG7ENSP000002222124STRING: ENSP00000222212
CNIH2ENSP000003100034STRING: ENSP00000310003
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Gene Ontology (GO): 4 biological process terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0035249synaptic transmission, glutamatergic IEA--
GO:0035556intracellular signal transduction IEA--
GO:0042391regulation of membrane potential IEA--
GO:2000311regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity IDA--

Find genes that share ontologies with CNIH3           About GenesLikeMe



(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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Browse Small Molecules at EMD Millipore
   Browse drugs & compounds from Enzo Life Sciences
  Browse compounds at ApexBio 

Browse Tocris compounds for CNIH3



(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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REFSEQ mRNAs for CNIH3 gene: 
NM_152495.1  

14 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000471578 ENST00000483512 ENST00000498126 ENST00000496372 ENST00000470602
ENST00000498382 ENST00000478120 ENST00000481095 ENST00000470788 ENST00000489556
ENST00000496277 ENST00000492470 ENST00000479227 ENST00000272133(uc001hos.1)

miRNA
Products:
     
Block miRNA regulation of human, mouse, rat CNIH3 using miScript Target Protectors
Selected qRT-PCR Assays for microRNAs that regulate CNIH3 (see all 16):
hsa-miR-21* hsa-miR-4289 hsa-miR-1226 hsa-miR-513a-5p hsa-miR-2110 hsa-miR-4312 hsa-miR-15a hsa-miR-497
SwitchGear 3'UTR luciferase reporter plasmidCNIH3 3' UTR sequence
Inhib. RNA
Products:
     
OriGene RNAi products in human, mouse, rat for CNIH3
Predesigned siRNA for gene silencing in human, mouse, rat CNIH3
Clone
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OriGene clones in human, mouse for CNIH3 (see all 9)
OriGene ORF clones in mouse, rat for CNIH3
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector: CNIH3 (NM_152495)
DNA2.0 Custom Codon Optimized Gene Synthesis Service for CNIH3
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CNIH3
Primer
Products:
    
OriGene qPCR primer pairs and template standards for CNIH3
OriGene qSTAR qPCR primer pairs in human, mouse for CNIH3
Pre-validated RT2 qPCR Primer Assay in human, mouse, rat CNIH3
  QuantiTect SYBR Green Assays in human, mouse, rat CNIH3
  QuantiFast Probe-based Assays in human, mouse, rat CNIH3

Selected AceView cDNA sequences (see all 80):

CK822707 NM_152495 BM972532 AF070524 CB141048 BF593434 BM509970 AL121016 
CR595048 CR625980 BU947589 AK096312 BX441105 AI142850 BE350918 BX430973 
BF339773 BF315626 AW613067 BG280978 BG476010 BG431100 BM906927 AI081862 

GeneLoc Exon Structure


(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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CNIH3 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: ATCAAGGTGT
CNIH3 Expression
About this image


CNIH3 expression in embryonic tissues and stem cells    About this table
Data from LifeMap, the Embryonic Development and Stem Cells Database
 selected tissues (see all 3) fully expand
 
 Brain (Nervous System)    fully expand to see all 3 entries
         Cerebral Cortex
 
 Neural Tube (Nervous System)    fully expand to see all 2 entries
         Telencephalon
 
 Spinal Cord (Nervous System)
CNIH3 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

CNIH3 Protein Expression

UniProtKB/Swiss-Prot: CNIH3_HUMAN, Q8TBE1
Tissue specificity: Expression is up-regulated in dorsolateral prefrontal cortex of patients with schizophrenia
(postmortem brain study)

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QuantiFast Probe-based Assays in human, mouse, rat CNIH3
In Situ
Assay Products:
 

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CNIH3

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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This gene was present in the common ancestor of animals and fungi.

Orthologs for CNIH3 gene from Selected species (see all 15)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
mouse
(Mus musculus)
Mammalia Cnih31 , 5 cornichon homolog 3 (Drosophila)1, 5 91.04(n)1
100(a)1
  1 (84.53 cM)5
729781  NM_001160211.11  NP_001153683.11 
 1813526285 
chicken
(Gallus gallus)
Aves CNIH31 cornichon homolog 3 (Drosophila) 84.58(n)
98.12(a)
  421323  XM_419388.4  XP_419388.3 
lizard
(Anolis carolinensis)
Reptilia CNIH36
cornichon family AMPA receptor auxiliary protein 3...
94(a)
1 ↔ 1
1(252498412-252600451)
tropical clawed frog
(Xenopus tropicalis)
Amphibia cnih31 cornichon homolog 3 (Drosophila) 80.62(n)
92.5(a)
  100497549  XM_002939751.2  XP_002939797.1 
zebrafish
(Danio rerio)
Actinopterygii cnih31 cornichon homolog 3 (Drosophila) 77(n)
82.28(a)
  564015  XM_005160806.1  XP_005160863.1 
fruit fly
(Drosophila melanogaster)
Insecta cni6
cornichon
53(a)
1 → many
2L(16309594-16310736)
worm
(Caenorhabditis elegans)
Secernentea cni-16
Y64H9A.16
Protein Y64H9A.1 (Y64H9A.1) mRNA, complete cds
52(a)
52(a)
many ↔ many
many ↔ many
V(13180330-13181529) WBGene00011648
X(5057363-5057581) WBGene00022023
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes ERV146
ERV156
Protein localized to COPII-coated vesicles, involv...
Protein involved in export of proteins from the en...
28(a)
25(a)
many ↔ many
many ↔ many
VII(400871-401287) YGL054C
II(645550-645978) YBR210W


ENSEMBL Gene Tree for CNIH3 (if available)
TreeFam Gene Tree for CNIH3 (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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Paralogs for CNIH3 gene
CNIH12  CNIH42  CNIH22  
4 SIMAP similar genes for CNIH3 using alignment to 1 protein entry:     CNIH3_HUMAN:
CNIH2    CNIH1    CNIH    CNIH4

Find genes that share paralogs with CNIH3           About GenesLikeMe



(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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Selected SNPs for CNIH3 (see all 2359)    About this table                                 

Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 1 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs1484350531,2
--224802209(+) TGTCTA/GCAAAC 1 -- us2k10--------
rs1861483711,2
--224802299(+) GATAGC/TACCAC 1 -- us2k10--------
rs1179783661,2
F--224802347(+) AAAAAA/GATAAA 1 -- us2k11Minor allele frequency- G:0.03EA 120
rs1906058371,2
C--224802452(+) GAGACC/TATCTT 1 -- us2k10--------
rs612473051,2
C--224802477(+) AACCCC/TGTCTT 1 -- us2k10--------
rs1475646291,2
C--224802570(+) CTTGAA/GCCAGG 1 -- us2k10--------
rs1486974951,2
C--224802639(+) CCGTC-/AAATA 
 AATAAAT
AAATA
1 -- us2k10--------
rs1496450701,2
--224802639(+) CCGTC-/AAATAAATA
AATAAATAAAT
AAATA
1 -- us2k10--------
rs1462580431,2
--224802814(+) CCCTTC/TCAGCT 1 -- us2k10--------
rs1822581981,2
--224802831(+) GCATTA/GGAATC 1 -- us2k10--------

HapMap Linkage Disequilibrium report for CNIH3 (224622362 - 224872362 bp, first 250kb of CNIH3)

Structural Variations
     Database of Genomic Variants (DGV) 6 variations for CNIH3:    About this table    
Variant IDTypeSubtypePubMed ID
esv2670242CNV Deletion23128226
esv2723761CNV Deletion23290073
dgv102n67CNV Loss20364138
esv26044CNV Loss19812545
nsv524125CNV Gain19592680
esv24936CNV Gain19812545

Site Specific Mutation Identification with PCR Assays
SeqTarget long-range PCR primers for resequencing CNIH3
DNA2.0 Custom Variant and Variant Library Synthesis for CNIH3

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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Find genes that share disorders with CNIH3           About GenesLikeMe

Genetic Association Database (GAD): CNIH3
Human Genome Epidemiology (HuGE) Navigator: CNIH3 (1 document)

Export disorders for CNIH3 gene to outside databases

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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PubMed articles for CNIH3 gene, integrated from 10 sources (see all 12):
(articles sorted by number of sources associating them with CNIH3)
    Utopia: connect your pdf to the dynamic
world of online information

  1. Upregulation of cornichon transcripts in the dorsolateral prefrontal cortex in schizophrenia. (PubMed id 23103966)1, 2 Drummond J.B....Meador-Woodruff J.H. (Neuroreport 2012)
  2. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
  3. The DNA sequence and biological annotation of human chromosome 1. (PubMed id 16710414)1, 2 Gregory S.G.... Bentley D.R. (Nature 2006)
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
  5. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
  6. Large-scale concatenation cDNA sequencing. (PubMed id 9110174)1, 3 Yu W.... Gibbs R.A. (Genome Res. 1997)
  7. A "double adaptor" method for improved shotgun library construction. (PubMed id 8619474)1, 3 Andersson B.... Gibbs R.A. (Anal. Biochem. 1996)
  8. Functional comparison of the effects of TARPs and cornichons on AMPA receptor trafficking and gating. (PubMed id 20805473)2 Shi Y....Nicoll R.A. (Proc. Natl. Acad. Sci. U.S.A. 2010)
  9. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)1 Lamesch P.... Vidal M. (Genomics 2007)
  10. Genome-wide association of echocardiographic dimensions, brachial artery endothelial function and treadmill exercise responses in the Framingham Heart Study. (PubMed id 17903301)4 Vasan R.S....Benjamin E.J. (BMC Med. Genet. 2007)

(in PubMed, OMIM, and NCBI Bookshelf)
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 ANDOR
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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 149111 HGNC: 26802 AceView: FLJ38993 Ensembl:ENSG00000143786 euGenes: HUgn149111
ECgene: CNIH3 H-InvDB: CNIH3

(According to HUGE)
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  --

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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NameDescription
PharmGKB entry for CNIH3 Pharmacogenomics, SNPs, Pathways

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
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Patent Information for CNIH3 gene:
Search GeneIP for patents involving CNIH3

GeneCards and IP:
Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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