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Aliases for CNBD2 Gene

Aliases for CNBD2 Gene

  • Cyclic Nucleotide Binding Domain Containing 2 2 3 5
  • Cyclic Nucleotide (CNMP) Binding Domain Containing 1 2 3
  • C20orf152 3 4
  • Chromosome 20 Open Reading Frame 152 2
  • CNMPD1 3

External Ids for CNBD2 Gene

Previous HGNC Symbols for CNBD2 Gene

  • C20orf152
  • CNMPD1

Previous GeneCards Identifiers for CNBD2 Gene

  • GC20P034557

Summaries for CNBD2 Gene

GeneCards Summary for CNBD2 Gene

CNBD2 (Cyclic Nucleotide Binding Domain Containing 2) is a Protein Coding gene. GO annotations related to this gene include cAMP binding.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CNBD2 Gene

Genomics for CNBD2 Gene

Regulatory Elements for CNBD2 Gene

Enhancers for CNBD2 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around CNBD2 on UCSC Golden Path with GeneCards custom track

Promoters for CNBD2 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around CNBD2 on UCSC Golden Path with GeneCards custom track

Genomic Location for CNBD2 Gene

35,954,562 bp from pter
36,030,700 bp from pter
76,139 bases
Plus strand

Genomic View for CNBD2 Gene

Genes around CNBD2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CNBD2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CNBD2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CNBD2 Gene

Proteins for CNBD2 Gene

  • Protein details for CNBD2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Cyclic nucleotide-binding domain-containing protein 2
    Protein Accession:
    Secondary Accessions:
    • Q14C79
    • Q5JWY7
    • Q5T3S1
    • Q9BR36
    • Q9BWY5

    Protein attributes for CNBD2 Gene

    576 amino acids
    Molecular mass:
    67512 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for CNBD2 Gene


neXtProt entry for CNBD2 Gene

Proteomics data for CNBD2 Gene at MOPED

Post-translational modifications for CNBD2 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for CNBD2 Gene

Domains & Families for CNBD2 Gene

Protein Domains for CNBD2 Gene

Suggested Antigen Peptide Sequences for CNBD2 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Contains 1 cyclic nucleotide-binding domain.
  • Contains 1 cyclic nucleotide-binding domain.
genes like me logo Genes that share domains with CNBD2: view

No data available for Gene Families for CNBD2 Gene

Function for CNBD2 Gene

genes like me logo Genes that share phenotypes with CNBD2: view

Animal Models for CNBD2 Gene

MGI Knock Outs for CNBD2:

Animal Model Products

miRNA for CNBD2 Gene

miRTarBase miRNAs that target CNBD2

Inhibitory RNA Products

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for CNBD2 Gene

Localization for CNBD2 Gene

Subcellular locations from

Jensen Localization Image for CNBD2 Gene COMPARTMENTS Subcellular localization image for CNBD2 gene
Compartment Confidence
cytosol 3
mitochondrion 2
endoplasmic reticulum 1
golgi apparatus 1
nucleus 1
peroxisome 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for CNBD2 Gene

Pathways & Interactions for CNBD2 Gene

SuperPathways for CNBD2 Gene

No Data Available

Interacting Proteins for CNBD2 Gene

Gene Ontology (GO) - Biological Process for CNBD2 Gene


No data available for Pathways by source and SIGNOR curated interactions for CNBD2 Gene

Drugs & Compounds for CNBD2 Gene

No Compound Related Data Available

Transcripts for CNBD2 Gene

Unigene Clusters for CNBD2 Gene

Cyclic nucleotide binding domain containing 2:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for CNBD2 Gene

No ASD Table

Relevant External Links for CNBD2 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for CNBD2 Gene

mRNA expression in normal human tissues for CNBD2 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for CNBD2 Gene

This gene is overexpressed in Testis (x40.7).

Protein differential expression in normal tissues from HIPED for CNBD2 Gene

This gene is overexpressed in Pancreatic juice (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for CNBD2 Gene

SOURCE GeneReport for Unigene cluster for CNBD2 Gene Hs.732697

genes like me logo Genes that share expression patterns with CNBD2: view

Protein tissue co-expression partners for CNBD2 Gene

- Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA Expression by UniProt/SwissProt for CNBD2 Gene

Orthologs for CNBD2 Gene

This gene was present in the common ancestor of chordates.

Orthologs for CNBD2 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia CNMPD1 35
  • 81.37 (n)
  • 72.93 (a)
CNBD2 36
  • 71 (a)
(Canis familiaris)
Mammalia CNMPD1 35
  • 83.54 (n)
  • 75.57 (a)
CNBD2 36
  • 72 (a)
(Mus musculus)
Mammalia Cnbd2 35
  • 75.78 (n)
  • 66.19 (a)
Cnbd2 16
Cnbd2 36
  • 55 (a)
(Pan troglodytes)
Mammalia CNMPD1 35
  • 98.89 (n)
  • 97.73 (a)
CNBD2 36
  • 97 (a)
(Monodelphis domestica)
Mammalia CNBD2 36
  • 45 (a)
(Ornithorhynchus anatinus)
Mammalia CNBD2 36
  • 30 (a)
(Anolis carolinensis)
Reptilia CNBD2 36
  • 48 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC100486705 35
  • 52.97 (n)
  • 44.9 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 36
  • 22 (a)
Species with no ortholog for CNBD2:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for CNBD2 Gene

Gene Tree for CNBD2 (if available)
Gene Tree for CNBD2 (if available)

Paralogs for CNBD2 Gene

(1) SIMAP similar genes for CNBD2 Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with CNBD2: view

No data available for Paralogs for CNBD2 Gene

Variants for CNBD2 Gene

Sequence variations from dbSNP and Humsavar for CNBD2 Gene

SNP ID Clin Chr 20 pos Sequence Context AA Info Type
rs17347958 - 35,972,687(+) GTTCC(A/G)CCAAG nc-transcript-variant, upstream-variant-2KB, reference, missense
rs6142471 - 35,984,684(+) AAGAA(A/G)CGGAG nc-transcript-variant, reference, missense
rs6060750 - 36,008,449(+) CTCTC(C/T)CCAAG nc-transcript-variant, reference, missense
rs1891151 -- 36,024,804(+) gtggc(A/G/T)ggcac intron-variant
rs1891152 -- 36,024,887(+) CCAAG(G/T)TTGCA intron-variant

Variation tolerance for CNBD2 Gene

Residual Variation Intolerance Score: 96.1% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 12.18; 93.95% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for CNBD2 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for CNBD2 Gene

Disorders for CNBD2 Gene

Relevant External Links for CNBD2

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for CNBD2 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CNBD2 Gene

Publications for CNBD2 Gene

  1. The DNA sequence and comparative analysis of human chromosome 20. (PMID: 11780052) Deloukas P. … Rogers J. (Nature 2001) 2 3 4 67
  2. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for CNBD2 Gene

Sources for CNBD2 Gene