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Aliases for CNBD1 Gene

Aliases for CNBD1 Gene

  • Cyclic Nucleotide Binding Domain Containing 1 2 3 5

External Ids for CNBD1 Gene

Previous GeneCards Identifiers for CNBD1 Gene

  • GC08P087948
  • GC08P083088

Summaries for CNBD1 Gene

GeneCards Summary for CNBD1 Gene

CNBD1 (Cyclic Nucleotide Binding Domain Containing 1) is a Protein Coding gene.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CNBD1 Gene

Genomics for CNBD1 Gene

Regulatory Elements for CNBD1 Gene

Enhancers for CNBD1 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around CNBD1 on UCSC Golden Path with GeneCards custom track

Genomic Location for CNBD1 Gene

Chromosome:
8
Start:
86,866,442 bp from pter
End:
87,615,219 bp from pter
Size:
748,778 bases
Orientation:
Plus strand

Genomic View for CNBD1 Gene

Genes around CNBD1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CNBD1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CNBD1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CNBD1 Gene

Proteins for CNBD1 Gene

  • Protein details for CNBD1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q8NA66-CNBD1_HUMAN
    Recommended name:
    Cyclic nucleotide-binding domain-containing protein 1
    Protein Accession:
    Q8NA66

    Protein attributes for CNBD1 Gene

    Size:
    436 amino acids
    Molecular mass:
    50224 Da
    Quaternary structure:
    No Data Available

neXtProt entry for CNBD1 Gene

Proteomics data for CNBD1 Gene at MOPED

Post-translational modifications for CNBD1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for CNBD1 Gene

No data available for DME Specific Peptides for CNBD1 Gene

Domains & Families for CNBD1 Gene

Protein Domains for CNBD1 Gene

Suggested Antigen Peptide Sequences for CNBD1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

Q8NA66

UniProtKB/Swiss-Prot:

CNBD1_HUMAN :
  • Contains 1 cyclic nucleotide-binding domain.
Domain:
  • Contains 1 cyclic nucleotide-binding domain.
genes like me logo Genes that share domains with CNBD1: view

No data available for Gene Families for CNBD1 Gene

Function for CNBD1 Gene

Phenotypes for CNBD1 Gene

MGI mutant phenotypes for CNBD1:
inferred from 1 alleles
GenomeRNAi human phenotypes for CNBD1:
genes like me logo Genes that share phenotypes with CNBD1: view

Animal Models for CNBD1 Gene

MGI Knock Outs for CNBD1:

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , miRNA , Transcription Factor Targets and HOMER Transcription for CNBD1 Gene

Localization for CNBD1 Gene

Subcellular locations from

COMPARTMENTS
Jensen Localization Image for CNBD1 Gene COMPARTMENTS Subcellular localization image for CNBD1 gene
Compartment Confidence
cytosol 2
mitochondrion 2

No data available for Subcellular locations from UniProtKB/Swiss-Prot and Gene Ontology (GO) - Cellular Components for CNBD1 Gene

Pathways & Interactions for CNBD1 Gene

SuperPathways for CNBD1 Gene

No Data Available

Interacting Proteins for CNBD1 Gene

Gene Ontology (GO) - Biological Process for CNBD1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for CNBD1 Gene

Drugs & Compounds for CNBD1 Gene

No Compound Related Data Available

Transcripts for CNBD1 Gene

mRNA/cDNA for CNBD1 Gene

(1) REFSEQ mRNAs :
(3) Additional mRNA sequences :
(7) Selected AceView cDNA sequences:
(7) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for CNBD1 Gene

Cyclic nucleotide binding domain containing 1:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for CNBD1 Gene

No ASD Table

Relevant External Links for CNBD1 Gene

GeneLoc Exon Structure for
CNBD1
ECgene alternative splicing isoforms for
CNBD1

Expression for CNBD1 Gene

mRNA expression in normal human tissues for CNBD1 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for CNBD1 Gene

This gene is overexpressed in Testis (x51.6).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for CNBD1 Gene



SOURCE GeneReport for Unigene cluster for CNBD1 Gene Hs.246284

genes like me logo Genes that share expression patterns with CNBD1: view

Protein tissue co-expression partners for CNBD1 Gene

Primer Products

No data available for Protein differential expression in normal tissues and mRNA Expression by UniProt/SwissProt for CNBD1 Gene

Orthologs for CNBD1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for CNBD1 Gene

Organism Taxonomy Gene Similarity Type Details
cow
(Bos Taurus)
Mammalia CNBD1 35
  • 81.52 (n)
  • 73.78 (a)
dog
(Canis familiaris)
Mammalia CNBD1 35
  • 83.18 (n)
  • 71.76 (a)
CNBD1 36
  • 60 (a)
OneToOne
mouse
(Mus musculus)
Mammalia Cnbd1 35
  • 70.72 (n)
  • 57.48 (a)
Cnbd1 16
Cnbd1 36
  • 57 (a)
OneToOne
chimpanzee
(Pan troglodytes)
Mammalia CNBD1 35
  • 99.31 (n)
  • 97.93 (a)
CNBD1 36
  • 98 (a)
OneToOne
rat
(Rattus norvegicus)
Mammalia Cnbd1 35
  • 71.19 (n)
  • 60.66 (a)
oppossum
(Monodelphis domestica)
Mammalia CNBD1 36
  • 35 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 44 (a)
OneToMany
-- 36
  • 31 (a)
OneToMany
-- 36
  • 44 (a)
OneToMany
lizard
(Anolis carolinensis)
Reptilia CNBD1 36
  • 40 (a)
OneToOne
zebrafish
(Danio rerio)
Actinopterygii LOC100535758 35
  • 49.14 (n)
  • 40.43 (a)
CNBD1 36
  • 26 (a)
OneToOne
Species with no ortholog for CNBD1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for CNBD1 Gene

ENSEMBL:
Gene Tree for CNBD1 (if available)
TreeFam:
Gene Tree for CNBD1 (if available)

Paralogs for CNBD1 Gene

No data available for Paralogs for CNBD1 Gene

Variants for CNBD1 Gene

Sequence variations from dbSNP and Humsavar for CNBD1 Gene

SNP ID Clin Chr 08 pos Sequence Context AA Info Type
rs10504829 - 86,905,112(+) CTCAC(A/C/G)ATACA reference, missense
rs16894901 - 86,905,127(+) TGAAG(A/C)AATAT reference, missense
rs60556175 - 87,237,110(+) ACTCA(A/G)TGGTA reference, missense
rs2030726 -- 87,079,019(+) CCCCC(A/C/G)CTTTT intron-variant
rs2060120 -- 87,216,791(+) ATTAA(A/G)CTATA intron-variant

Structural Variations from Database of Genomic Variants (DGV) for CNBD1 Gene

Variant ID Type Subtype PubMed ID
esv2422239 CNV Duplication 17116639
nsv465734 CNV Gain 19166990
nsv891158 CNV Loss 21882294
nsv831383 CNV Gain 17160897
esv1731753 CNV Insertion 17803354
nsv398035 CNV Loss 16902084
esv1125411 CNV Insertion 17803354
nsv891160 CNV Gain 21882294
esv2669887 CNV Deletion 23128226
nsv891161 CNV Gain 21882294
esv2673295 CNV Deletion 23128226
esv2661135 CNV Deletion 23128226
nsv891162 CNV Gain+Loss 21882294
esv2737269 CNV Deletion 23290073
nsv891163 CNV Loss 21882294
nsv525991 CNV Loss 19592680

Variation tolerance for CNBD1 Gene

Residual Variation Intolerance Score: 95.2% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 4.28; 62.67% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Relevant External Links for CNBD1 Gene

Disorders for CNBD1 Gene

Relevant External Links for CNBD1

Genetic Association Database (GAD)
CNBD1
Human Genome Epidemiology (HuGE) Navigator
CNBD1
Atlas of Genetics and Cytogenetics in Oncology and Haematology:
CNBD1

No disorders were found for CNBD1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CNBD1 Gene

Publications for CNBD1 Gene

  1. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose J.E. … Uhl G.R. (Mol. Med. 2010) 3 48 67
  2. Genetic variants associated with disordered eating. (PMID: 23568457) Wade T.D. … Martin N.G. (Int J Eat Disord 2013) 3
  3. [The influence of calcineurin gene polymorphism on morphofunctional characteristics of cardiovascular system of athletes]. (PMID: 18825932) Akhmetov I.I. … Rogozkin V.A. (Ross Fiziol Zh Im I M Sechenova 2008) 3
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for CNBD1 Gene

Sources for CNBD1 Gene

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