Aliases for CMTR1 Gene
External Ids for CMTR1 Gene
Previous Symbols for CMTR1 Gene
GeneCards Summary for CMTR1 Gene
CMTR1 (Cap Methyltransferase 1) is a Protein Coding gene. GO annotations related to this gene include nucleic acid binding and mRNA (nucleoside-2-O-)-methyltransferase activity. An important paralog of this gene is CMTR2.
UniProtKB/Swiss-Prot for CMTR1 Gene
S-adenosyl-L-methionine-dependent methyltransferase that mediates mRNA cap1 2-O-ribose methylation to the 5-cap structure of mRNAs. Methylates the ribose of the first nucleotide of a m(7)GpppG-capped mRNA and small nuclear RNA (snRNA) to produce m(7)GpppRm (cap1). Displays a preference for cap0 transcripts. Cap1 modification is linked to higher levels of translation. May be involved in the interferon response pathway.