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CMTR1 Gene

protein-coding   GIFtS: 40
GCID: GC06P037506

Cap Methyltransferase 1

(Previous names: KIAA0082, FtsJ methyltransferase domain containing 2)
(Previous symbols: KIAA0082, FTSJD2)
  Search for CMTR1
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Cap Methyltransferase 11 2 3     ISG952 3
FTSJD21 2 3     MTr12 3
KIAA00821 2 3     hMTr12 3
FtsJ Methyltransferase Domain Containing 21 2     Cap-Specific MRNA (Nucleoside-2'-O-)-Methyltransferase 12
Cap1 2'O-Ribose Methyltransferase 12 3     S-Adenosyl-L-Methionine-Dependent Methyltransferase FTSJD22
FtsJ Methyltransferase Domain-Containing Protein 22 3     EC 2.1.1.573
Interferon-Stimulated Gene 95 KDa Protein2 3     MTR13

External Ids:    HGNC: 210771   Entrez Gene: 230702   Ensembl: ENSG000001372007   UniProtKB: Q8N1G23   

Export aliases for CMTR1 gene to outside databases

Previous GC identifer: GC06P037401


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for CMTR1 Gene:
CMTR1 (cap methyltransferase 1) is a protein-coding gene. GO annotations related to this gene include mRNA (nucleoside-2'-O-)-methyltransferase activity and nucleic acid binding. An important paralog of this gene is CMTR2.

UniProtKB/Swiss-Prot: CMTR1_HUMAN, Q8N1G2
Function: S-adenosyl-L-methionine-dependent methyltransferase that mediates mRNA cap1 2'-O-ribose methylation to
the 5'-cap structure of mRNAs. Methylates the ribose of the first nucleotide of a m(7)GpppG-capped mRNA and small
nuclear RNA (snRNA) to produce m(7)GpppRm (cap1). Displays a preference for cap0 transcripts. Cap1 modification
is linked to higher levels of translation. May be involved in the interferon response pathway




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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Regulatory elements:
   Search for regulatory transcription factor binding sites for CMTR1
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCMTR1 promoter sequence
   Search Chromatin IP Primers for CMTR1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat CMTR1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6p21.2   Ensembl cytogenetic band:  6p21.2   HGNC cytogenetic band: 6p21.2

CMTR1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CMTR1 gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06P037506:  view genomic region     (about GC identifiers)

Start:
37,400,907 bp from pter      End:
37,450,603 bp from pter
Size:
49,697 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: CMTR1_HUMAN, Q8N1G2 (See protein sequence)
Recommended Name: Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1  
Size: 835 amino acids; 95321 Da
Subunit: Interacts with POLR2A (via C-terminus)
Sequence caution: Sequence=BAA07893.2; Type=Erroneous initiation; Note=Translation N-terminally shortened;
3 PDB 3D structures from and Proteopedia for CMTR1:
4N48 (3D)        4N49 (3D)        4N4A (3D)    
Secondary accessions: A8K949 Q14670 Q96FJ9

Explore the universe of human proteins at neXtProt for CMTR1: NX_Q8N1G2

Explore proteomics data for CMTR1 at MOPED

Post-translational modifications: 

  • Ubiquitination2 at Lys487, Lys608, Lys777, Lys823
  • Modification sites at PhosphoSitePlus

  • See CMTR1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_055865.1  
    ENSEMBL proteins: 
     ENSP00000414233   ENSP00000362550   ENSP00000432114   ENSP00000393893  

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    Novus Biologicals CMTR1 Protein
    Novus Biologicals CMTR1 Lysates
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    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp.

     
    Search eBioscience for Proteins for CMTR1 

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    LSBio Antibodies in human, mouse, rat for CMTR1

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    Search eBioscience for ELISAs for CMTR1 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    GPATCH: G patch domain containing

    4 InterPro protein domains:
     IPR025816 Cap_mRNA_MeTrfase_1
     IPR000467 G_patch_dom
     IPR001202 WW_dom
     IPR002877 rRNA_MeTrfase_FtsJ_dom

    Graphical View of Domain Structure for InterPro Entry Q8N1G2

    ProtoNet protein and cluster: Q8N1G2

    1 Blocks protein domain: IPB000467 D111/G-patch domain

    UniProtKB/Swiss-Prot: CMTR1_HUMAN, Q8N1G2
    Similarity: Contains 1 G-patch domain
    Similarity: Contains 1 RrmJ-type SAM-dependent 2'-O-MTase domain
    Similarity: Contains 1 WW domain


    Find genes that share domains with CMTR1           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: CMTR1_HUMAN, Q8N1G2
    Function: S-adenosyl-L-methionine-dependent methyltransferase that mediates mRNA cap1 2'-O-ribose methylation to
    the 5'-cap structure of mRNAs. Methylates the ribose of the first nucleotide of a m(7)GpppG-capped mRNA and small
    nuclear RNA (snRNA) to produce m(7)GpppRm (cap1). Displays a preference for cap0 transcripts. Cap1 modification
    is linked to higher levels of translation. May be involved in the interferon response pathway
    Catalytic activity: S-adenosyl-L-methionine + m(7)G(5')pppR-RNA = S-adenosyl-L-homocysteine + m(7)G(5')pppRm-RNA
    Induction: By interferons alpha and beta, and by Vaccinia virus infection

         Enzyme Number (IUBMB): EC 2.1.1.571

         Gene Ontology (GO): 4 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003676nucleic acid binding IEA--
    GO:0004483mRNA (nucleoside-2'-O-)-methyltransferase activity IDA--
    GO:0005515protein binding ----
    GO:0008168methyltransferase activity ----
         
    Find genes that share ontologies with CMTR1           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for CMTR1:
     Synthetic lethal with Ras 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for CMTR1
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for CMTR1
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for CMTR1

    miRNA
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    miRTarBase miRNAs that target CMTR1:
    hsa-mir-335-5p (MIRT017033), hsa-mir-193b-3p (MIRT041458), hsa-mir-1226-3p (MIRT036489)

    Block miRNA regulation of human, mouse, rat CMTR1 using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate CMTR1
    SwitchGear 3'UTR luciferase reporter plasmidCMTR1 3' UTR sequence
    Inhib. RNA
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    Predesigned siRNA for gene silencing in human, mouse, rat CMTR1

    Gene Editing
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CMTR1


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    CMTR1_HUMAN, Q8N1G2: Nucleus

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--
    GO:0005730NOT nucleolus IDA--
    GO:0005737cytoplasm IDA--

    Find genes that share ontologies with CMTR1           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for CMTR1
    Interactions:

        Search GeneGlobe Interaction Network for CMTR1

    STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

    4 Interacting proteins for CMTR1 (Q8N1G23 ENSP000003625504) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CTNNB1P352223I2D: score=1 
    PRKAR1AP106443I2D: score=1 
    TPP1ENSP000002994274STRING: ENSP00000299427
    UBCENSP000003448184STRING: ENSP00000344818
    About this table

    Gene Ontology (GO): 4 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:00063707-methylguanosine mRNA capping IMP--
    GO:0032259methylation ----
    GO:0080009mRNA methylation IDA--
    GO:0097309cap1 mRNA methylation IDA--

    Find genes that share ontologies with CMTR1           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for CMTR1



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for CMTR1 gene: 
    NM_015050.2  

    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000471097 ENST00000455891 ENST00000373451(uc010jwu.2 uc003ons.3)
    ENST00000493656 ENST00000475364 ENST00000457419
    miRNA
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    Predesigned siRNA for gene silencing in human, mouse, rat CMTR1
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    OriGene qPCR primer pairs and template standards for CMTR1
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      QuantiTect SYBR Green Assays in human, mouse, rat CMTR1
      QuantiFast Probe-based Assays in human, mouse, rat CMTR1

    Selected AceView cDNA sequences (see all 304):

    AI700489 AA938712 CA398168 BM129207 BQ884260 AI216414 CB529697 AI983669 
    BQ066803 BC010731 D43949 BM666845 CA398167 AI671639 Z44296 AL045278 
    BM695062 BM793651 BP345095 AL043565 AI185685 BQ645374 BQ706205 BQ054629 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for CMTR1 (see all 9)    About this scheme

    ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8 ^ 9 ^ 10 ^ 11 ^ 12 ^ 13a · 13b ^ 14 ^ 15a · 15b ^ 16 ^ 17 ^ 18 ^ 19 ^ 20 ^ 21a · 21b ^ 22a · 22b ^
    SP1:                                            -     -                                         -                                         -     -     -         
    SP2:                                -     -     -     -                                                                                                         
    SP3:                                                                    -     -     -     -     -                                                               
    SP4:                                                                                                                                                            
    SP5:                                                                                                                                                            

    ExUns: 23a · 23b ^ 24a · 24b ^ 25 ^ 26a · 26b ^ 27
    SP1:  -                 -                           
    SP2:                                                
    SP3:                                                
    SP4:  -                 -                           
    SP5:                                                


    ECgene alternative splicing isoforms for CMTR1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    CMTR1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    CMTR1 Expression
    About this image


    CMTR1 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 6) fully expand
     
     Brain (Nervous System)    fully expand to see all 4 entries
             Cerebral Cortex
     
     Testis (Reproductive System)
             Leydig Cells Testis Interstitium
     
     Trophoblast (Extraembryonic Tissues)
             Trophoblast Cells Trophoblast
     
     Ovary (Reproductive System)
             Oviduct
     
     Pancreas (Endocrine System)
             Islets of Langerhans
    CMTR1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    CMTR1 Protein Expression
        Custom PCR Arrays for CMTR1
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CMTR1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for CMTR1 gene from Selected species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Ftsjd25
    Cmtr11
    FtsJ methyltransferase domain containing 25
    cap methyltransferase 11
    87.3(n)1
    90.38(a)1
      17 (15.43 cM)5
    741571  NM_028791.51  NP_083067.11 
     296605955 
    chicken
    (Gallus gallus)
    Aves FTSJD21 FtsJ methyltransferase domain containing 2 76.72(n)
    84.56(a)
      421434  XM_004935385.1  XP_004935442.1 
    lizard
    (Anolis carolinensis)
    Reptilia CMTR16
    cap methyltransferase 1
    81(a)
    1 ↔ 1
    1(228248963-228281633)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.78962 Xenopus laevis transcribed sequence with weak similarity more 73.74(n)    BX850761.1 
    zebrafish
    (Danio rerio)
    Actinopterygii zgc553362 hypothetical protein MGC55336 74.18(n)   393102  BC044371.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG63791 CG6379 50(n)
    40.41(a)
      31355  NM_131920.3  NP_572148.2 
    worm
    (Caenorhabditis elegans)
    Secernentea CELE_Y53F4B.131 CELE_Y53F4B.13 51.75(n)
    42.9(a)
      175156  NM_001267528.1  NP_001254457.1 


    ENSEMBL Gene Tree for CMTR1 (if available)
    TreeFam Gene Tree for CMTR1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for CMTR1 gene
    CMTR22  
    1 SIMAP similar gene for CMTR1 using alignment to 4 protein entries:     CMTR1_HUMAN (see all proteins):
    FTSJD2

    Find genes that share paralogs with CMTR1           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for CMTR1 (see all 985)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 6 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs673779261,2
    C--37128888(+) AATCA-/TTTA  
            
    ATTAA
    1 -- int11Minor allele frequency- TTTA:0.00NA 2
    rs1863022801,2
    --37398957(+) ACATAA/CAAATT 1 -- us2k10--------
    rs1910491871,2
    --37399191(+) CCTAGA/CTCTGT 1 -- us2k10--------
    rs27769011,2
    C,F,A,H--37399261(+) tatctA/Gttgag 1 -- us2k116Minor allele frequency- G:0.23NS EA NA WA 2056
    rs2016792481,2
    C--37399330(+) TGTAC-/AGAGTTT 1 -- us2k10--------
    rs69256401,2
    C,F,A,H--37399569(+) acTCTT/AAAGAG 1 -- us2k16Minor allele frequency- A:0.06NS EA WA 712
    rs1406465021,2
    --37399590(+) TTTTGA/TTTTGT 1 -- us2k10--------
    rs1426804251,2
    --37399716(+) CCTACA/TGAGTA 1 -- us2k10--------
    rs799147081,2
    C,F--37400004(+) GGCCAT/CTTTAA 1 -- us2k11Minor allele frequency- C:0.02NA 120
    rs1840868141,2
    --37400016(+) GACATC/TAGCTT 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for CMTR1 (37400907 - 37450603 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for CMTR1: --
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing CMTR1
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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      --

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for CMTR1 gene, integrated from 10 sources (see all 23):
    (articles sorted by number of sources associating them with CMTR1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Characterization of hMTr1, a human Cap1 2'-O-Ribose methyltransferase. (PubMed id 20713356)1, 2, 3 Belanger F.... Pelletier J. (J. Biol. Chem. 2010)
    2. The human interferon-regulated ISG95 protein interacts with RNA polymerase II and shows methyltransferase activity. (PubMed id 18533109)1, 2 Haline-Vaz T.... Zanchin N.I.T. (Biochem. Biophys. Res. Commun. 2008)
    3. Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. (PubMed id 17081983)1, 2 Olsen J.V....Mann M. (Cell 2006)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    5. The DNA sequence and analysis of human chromosome 6. (PubMed id 14574404)1, 2 Mungall A.J.... Beck S. (Nature 2003)
    6. Prediction of the coding sequences of unidentified human genes. III. The coding sequences of 40 new genes (KIAA0081-KIAA0120) deduced by analysis of cDNA clones from human cell line KG-1. (PubMed id 7788527)1, 2 Nagase T.... Nomura N. (DNA Res. 1995)
    7. Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass. (PubMed id 23000965)1 Povlsen L.K....Choudhary C. (Nat. Cell Biol. 2012)
    8. Methods for quantification of in vivo changes in protein ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (amp 2012)
    9. 2'-O-ribose methylation of cap2 in human: function and evolution in a horizontally mobile family. (PubMed id 21310715)2 Werner M....Bujnicki J.M. (Nucleic Acids Res. 2011)
    10. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 23070 HGNC: 21077 AceView: KIAA0082 Ensembl:ENSG00000137200 euGenes: HUgn23070
    ECgene: CMTR1 H-InvDB: CMTR1

    (According to HUGE)
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    HUGE: KIAA0082

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for CMTR1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for CMTR1 gene:
    Search GeneIP for patents involving CMTR1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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