Aliases for CMTM8 Gene
External Ids for CMTM8 Gene
Previous HGNC Symbols for CMTM8 Gene
Previous GeneCards Identifiers for CMTM8 Gene
This gene belongs to the chemokine-like factor gene superfamily, a novel family that is similar to the chemokine and the transmembrane 4 superfamilies. This gene is one of several chemokine-like factor genes located in a cluster on chromosome 3. This gene acts as a tumor suppressor, and plays a role in regulating the migration of tumor cells. The encoded protein is thought to function as a a negative regulator of epidermal growth factor-induced signaling. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Feb 2016]
GeneCards Summary for CMTM8 Gene
CMTM8 (CKLF Like MARVEL Transmembrane Domain Containing 8) is a Protein Coding gene. GO annotations related to this gene include cytokine activity. An important paralog of this gene is PLLP.