Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

CMTM8 Gene

protein-coding   GIFtS: 49
GCID: GC03P032280

CKLF-like MARVEL transmembrane domain containing 8

(Previous names: chemokine-like factor super family 8, chemokine-like factor...)
(Previous symbol: CKLFSF8)
 Explore 1 disease affiliated with
CMTM8 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for CMTM8    

Aliases
for CMTM8 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
CKLF-Like MARVEL Transmembrane Domain Containing 81 2     Chemokine-Like Factor Superfamily Member 82 3
CKLFSF81 2 3     CKLFSF8-V22
Chemokine-Like Factor Super Family 81 2     CKLF-Like MARVEL Transmembrane Domain-Containing Protein 82
Chemokine-Like Factor Superfamily 81 2     

External Ids:    HGNC: 191791   Entrez Gene: 1521892   Ensembl: ENSG000001702937   OMIM: 6078915   UniProtKB: Q8IZV23   

Export aliases for CMTM8 gene to outside databases

Previous GC identifers: GC03P032256 GC03P032217


Summaries
for CMTM8 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for CMTM8:
This gene belongs to the chemokine-like factor gene superfamily, a novel family that is similar to the chemokine and
the transmembrane 4 superfamilies. This gene is one of several chemokine-like factor genes located in a cluster on
chromosome 3. This gene is widely expressed in many tissues, but the exact function of the encoded protein is unknown.
(provided by RefSeq, Jul 2008)




Genomic Views
for CMTM8 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000003.11  NC_018914.1  NT_022517.18  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the CMTM8 gene promoter:
         Max1   MIF-1   AP-2gamma   Evi-1   Arnt   E2F-1   E2F   Cart-1   Pax-4a   c-Myc   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: CMTM8 promoter sequence
   Search SABiosciences Chromatin IP Primers for CMTM8

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CMTM8


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3p22.3   Ensembl cytogenetic band:  3p22.3   HGNC cytogenetic band: 3p22.2

CMTM8 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CMTM8 gene location

GeneLoc information about chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03P032280:  view genomic region     (about GC identifiers)

Start:
 32,280,171 bp from pter      End:
 32,411,817 bp from pter
Size:
 131,647 bases      Orientation:
 plus strand

Proteins
for CMTM8 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: CKLF8_HUMAN, Q8IZV2 (See protein sequence)
Recommended Name: CKLF-like MARVEL transmembrane domain-containing protein 8  
Size: 173 amino acids; 19572 Da
Subcellular location: Isoform 1: Membrane; Multi-pass membrane protein
Subcellular location: Isoform 2: Cytoplasm. Nucleus
Secondary accessions: A5D6I7 Q8IW01
Alternative splicing: 2 isoforms:  Q8IZV2-1   Q8IZV2-2   

Explore the universe of human proteins at neXtProt for CMTM8: NX_Q8IZV2

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q8IZV2

    • CMTM8 Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_849199.2  
    ENSEMBL proteins: 
     ENSP00000412934   ENSP00000307741  

    Human Recombinant Protein Products: 
    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate: CMTM8
    OriGene Custom Protein Services for CMTM8 
    GenScript Custom Purified and Recombinant Proteins Services for CMTM8
    Novus Biologicals CMTM8 Proteins
    Novus Biologicals CMTM8 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for CMTM8

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005615extracellular space IEA--
    GO:0005634nucleus IEA--
    GO:0005737cytoplasm IEA--
    GO:0016021integral to membrane IEA--


    CMTM8 for ontologies           About GeneDecksing



    CMTM8 Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    Browse OriGene Antibodies
    OriGene Custom Antibody Services for CMTM8 
    GenScript Custom Superior Antibodies Services for CMTM8
    Novus Biologicals CMTM8 Antibody
    Search for Antibodies for CMTM8 at Abcam  
    Uscn Antibodies for CMTM8
    Search ThermoFisher Antibodies for CMTM8

    Assay Products for CMTM8: 
    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Immunoassay Development
    Browse OriGene Fluorogenic Cell Assay Kits
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for CMTM8
    Browse Enzo Life Sciences for kits & assays
    Uscn ELISAs and CLIAs for CMTM8

    Protein Domains /
    Families
    for CMTM8 gene

    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    CMTM8 for domains           About GeneDecksing

    3 InterPro domains/families:
     IPR013295 MAL
     IPR021128 MARVEL-like_dom
     IPR008253 Marvel

    Graphical View of Domain Structure for InterPro Entry Q8IZV2

    ProtoNet protein and cluster: Q8IZV2

    1 Blocks protein family: IPB008253 Marvel

    UniProtKB/Swiss-Prot: CKLF8_HUMAN, Q8IZV2
    Similarity: Belongs to the chemokine-like factor family
    Similarity: Contains 1 MARVEL domain


    Function
    for CMTM8 gene

    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section
    miRNA
    Products:            		 OriGene 3'-UTR Clone: CMTM8
    Browse MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat CMTM8
    4 QIAGEN miScript miRNA Assays for microRNAs that regulate CMTM8:
    hsa-miR-323-3p hsa-miR-495 hsa-miR-3613-3p hsa-miR-3144-3p
    SwitchGear 3'UTR luciferase reporter plasmid: CMTM8 3' UTR sequence
    Inhib. RNA
    Products:            		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CMTM8 (see all 7)
    OriGene shRNA RFP: CMTM8
    OriGene siRNA: CMTM8
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CMTM8

    Gene Editing
    Products:    		DNA2.0 Custom Protein Engineering Service for CMTM8

    Clone
    Products:             		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CMTM8 (see all 3)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CMTM8
    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector: CMTM8 (NM_178868)
    Sino Biological Human cDNA Clone for CMTM8
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CMTM8
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CMTM8 

    Cell Line
    Products:             		GenScript Custom overexpressing Cell Line Services for CMTM8
    Search LifeMap BioReagents cell lines for CMTM8

    In Situ Assay
    Products:       
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CMTM8

    Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005125cytokine activity IEA--


    CMTM8 for ontologies           About GeneDecksing



    Pathways & Interactions
    for CMTM8 gene

    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CMTM8

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    1 Interacting protein for CMTM8 (Q8IZV22, 3 ENSP000003077414) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    EGFRP005332, 3, ENSP000002754934MINT-72808 MINT-72809 MINT-72810 I2D: score=2 STRING: ENSP00000275493
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006935chemotaxis IEA--


    CMTM8 for ontologies           About GeneDecksing



    Drugs & Compounds
    for CMTM8 gene

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for CMTM8
    Search CenterWatch for drugs/clinical trials and news about CMTM8 / CKLF8 

    Transcripts
    for CMTM8 gene

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section
    REFSEQ mRNAs for CMTM8 gene: 
    NM_178868.3  

    Unigene Cluster for CMTM8:

    CKLF-like MARVEL transmembrane domain containing 8
    Hs.154986  [show with all ESTs]
    Unigene Representative Sequence: NM_178868
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000458535(uc010hfu.3) ENST00000307526(uc003cex.3)

    miRNA
    Products:             		 OriGene 3'-UTR Clone: CMTM8
    Browse OriGene MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat CMTM8
    4 QIAGEN miScript miRNA Assays for microRNAs that regulate CMTM8:
    hsa-miR-323-3p hsa-miR-495 hsa-miR-3613-3p hsa-miR-3144-3p
    SwitchGear 3'UTR luciferase reporter plasmid: CMTM8 3' UTR sequence
    Inhib. RNA
    Products:             		Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CMTM8 (see all 7)
    OriGene shRNA RFP: CMTM8
    OriGene siRNA: CMTM8
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CMTM8
    Clone
    Products:             		 OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CMTM8 (see all 3)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CMTM8
    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector: CMTM8 (NM_178868)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CMTM8
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CMTM8 
    Primer
    Products:            		 OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CMTM8
    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat CMTM8
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CMTM8
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CMTM8

    Additional cDNA sequence: 

    AF474370.2 AY598783.1 BC041390.2 

    3 DOTS entries:

    DT.100023114  DT.100023113  DT.100746081 

    24/45 AceView cDNA sequences (see all 45):

    BM785932 CB070190 NM_178868 AW024144 AI197788 AF474370 BQ224486 BG213702 
    BI791855 BQ186760 BC041390 BE869501 BU075644 BG656425 BG182013 BF793712 
    BG216957 AV660309 CB243247 BU506617 BM554032 BM663331 BG189930 AI185475 

    GeneLoc Exon Structure


    Expression
    for CMTM8 gene

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    CMTM8 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: --

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)
    About this image

    CMTM8 expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    4 LifeMap In Vivo Development Anatomical Compartments/Cells 
    Tissue Anatomical Compartment CellCategory (developmental path)
    EyeInner Nuclear LayerCholinergic Amacrine CellsAmacrine, Retina
    BrainMedulla OblongataBrain
    Neural TubeMetencephalonNeural Tube
    Spinal CordPresumptive Spinal CordSpinal Cord
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization
    Stem Cell Differentiation: 5 LifeMap Cells 
    NameCategory
    PureStem™ mesenchymal progenitor MEL2 (Embryonic Progenitor Cell)Adipose, Bone, Cartilage
    PureStem™ progenitor EN13 (Embryonic Progenitor Cell)
    PureStem™ progenitor EN2 (Embryonic Progenitor Cell)
    PureStem™ progenitor SM22 (Embryonic Progenitor Cell)
    PureStem™ progenitor W10 (Embryonic Progenitor Cell)

    See CMTM8 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for CMTM8

    SOURCE GeneReport for Unigene cluster: Hs.154986

    UniProtKB/Swiss-Prot: CKLF8_HUMAN, Q8IZV2
    Tissue specificity: Highly expressed in liver and pancreas

        SABiosciences Custom PCR Arrays for CMTM8
    Primer
    Products:    		 OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CMTM8
    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat CMTM8
    QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CMTM8
    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CMTM8
    In Situ
    Assay Products:     
         		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CMTM8

    Orthologs
    for CMTM8 gene

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section
    This gene was present in the common ancestor of chordates.

    Orthologs for CMTM8 gene from 4/12 species (see all 12)    About this table
    Organism Taxonomic
    classification    		 Gene Description Human
    Similarity    		 Orthology
    Type    		 Details
    mouse
    (Mus musculus)    		 Mammalia Cmtm81 , 5 CKLF-like MARVEL transmembrane domain containing 81, 5 86.71(n)1
    92.49(a)1    		   9 (65.20 cM)5
    700311  NM_027294.21  NP_081570.11 
     1147893455 
    chicken
    (Gallus gallus)    		 Aves CMTM81 CKLF-like MARVEL transmembrane domain containing 8 79(n)
    82.66(a)    		   420665  NM_001199703.1  NP_001186632.1 
    tropical clawed frog
    (Xenopus tropicalis)    		 Amphibia Str.187752 Transcribed sequence with weak similarity to protein more 84.11(n)    AL846822.2 
    zebrafish
    (Danio rerio)    		 Actinopterygii zgc:1586571 zgc:158657 62.45(n)
    51.9(a)    		   791163  NM_001080645.1  NP_001074114.1 


    ENSEMBL Gene Tree for CMTM8 (if available)
    TreeFam Gene Tree for CMTM8 (if available) 

    Paralogs
    for CMTM8 gene

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for CMTM8 gene
    MAL2  MALL2  PLLP2  
    3 SIMAP similar genes for CMTM8 using alignment to 1 protein entry:     CKLF8_HUMAN:
    PLLP    MALL    MAL

    CMTM8 for paralogs           About GeneDecksing



    Genomic Variants
    for CMTM8 gene

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/2403 NCBI SNPs in CMTM8 are shown (see all 2403)     About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance    		Chr 3 posSequence#AA
    Chg    		TypeMore#Allele
    freq    		PopTotal
    sample    		More
    ----------
    rs39247071,2
    		C,F,--32278202(-) CTGCAA/GTGTAA 1 -- us2k13Minor allele frequency- G:0.06WA NA EA 358
    rs98131461,2
    		C,A,--32278225(+) GCATAC/TACTTA 1 -- us2k13Minor allele frequency- T:0.21NA WA 122
    rs1811913221,2
    		--32278370(+) ATTCAA/TCTGAC 1 -- us2k10--------
    rs49552681,2
    		C,A,H,--32278646(+) GGGGTA/GGGGCT 1 -- us2k19Minor allele frequency- G:0.40NA WA EA 374
    rs49552691,2
    		C,H,--32278809(+) GGAATT/CTCTCC 1 -- us2k114Minor allele frequency- C:0.05NS EA NA CSA WA 664
    rs1425368411,2
    		C,--32278831(+) TTTGCC/TATGCT 1 -- us2k10--------
    rs1856053941,2
    		--32278929(+) TTGTCA/GTTTTT 1 -- us2k10--------
    rs1382207441,2
    		--32278935(+) TTTTT-/GCTTTC 1 -- us2k10--------
    rs98379231,2
    		C,F,H,--32278965(+) GACACT/CGTGAA 1 -- us2k120Minor allele frequency- C:0.44NS EA NA CSA WA 2344
    rs98382231,2
    		C,F,A,H,--32279180(+) CCATCT/GGTCAA 1 -- us2k121Minor allele frequency- G:0.43NS EA NA WA 2348

    HapMap Linkage Disequilibrium report for CMTM8 (32280171 - 32411817 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
    Database of Genomic Variants (DGV): 3 variations for CMTM8
         2 CNVs: 98277 6169
         1 Indel: 63435

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CMTM8
    DNA2.0 Custom Variant and Variant Library Synthesis for CMTM8

    Disorders / Diseases
    for CMTM8 gene

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    CMTM8 for disorders           About GeneDecksing

    OMIM gene information: 607891    OMIM disorders: --

    1 disease for CMTM8:    About MalaCards
    bipolar disorder

    Human Genome Epidemiology (HuGE) Navigator: CMTM8 (3 documents)

    Export disorders for CMTM8 gene to outside databases

    Publications
    for CMTM8 gene

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for CMTM8 gene, integrated from 9 sources (see all 16):
    (articles sorted by number of sources associating them with CMTM8)    		    Utopia: connect your pdf to the dynamic
    world of online information

    1. An alternative splice form of CMTM8 induces apoptosis. (PubMed id 17681841)1, 2, 9 Li D....Wang Y. (2007)
    2. Identification of eight genes encoding chemokine-like factor superfamily members 1-8 (CKLFSF1-8) by in silico cloning and experimental validation. (PubMed id 12782130)1, 2, 9 Han W.... Ma D. (2003)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. Regulation of EGF receptor signaling by the MARVEL domain-containing protein CKLFSF8. (PubMed id 16263120)1, 9 Jin C....Ma D. (2005)
    5. [Effect of novel human chemokine-like factor superfamily 8 on proliferation and EGFR expression of tumor cells] (PubMed id 16806010)1, 9 Huang Y.M. and Du Y. (2006)
    6. Down-regulation of CMTM8 induces epithelial-to-mesench ymal transition-like changes via c-MET/extracellular signal-regulated kinase (ER K) signaling. (PubMed id 22337876)1 Zhang W....Wang Y. (2012)
    7. Genomewide association study for determinants of HIV-1 acquisition and viral set point in HIV-1 serodiscordant couples with quantified virus exposure. (PubMed id 22174851)1 Lingappa J.R....Goldstein D. (2011)
    8. Propensity score-based nonparametric test revealing ge netic variants underlying bipolar disorder. (PubMed id 21254220)1 Jiang Y. and Zhang H. (2011)
    9. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1 Rose J.E....Uhl G.R. (2010)
    10. Findings from bipolar disorder genome-wide association studies replicate in a Finnish bipolar family-cohort. (PubMed id 19308021)1 Ollila H.M....Paunio T. (2009)

    External Searches for CMTM8 gene

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  
      Query String
    		PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    Genome Databases showing CMTM8 gene

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 152189 HGNC: 19179 AceView: CKLFSF8 Ensembl:ENSG00000170293 euGenes: HUgn152189
    ECgene: CMTM8 H-InvDB: CMTM8

    Other Databases showing CMTM8 gene

    (According to HUGE)
    About This Section
    		   --

    Specialized Databases showing CMTM8 gene

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for CMTM8 Pharmacogenomics, SNPs, Pathways

    Intellectual Property
    for CMTM8 gene

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    		Patent Information for CMTM8 gene:
    Search GeneIP for patents involving CMTM8

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    Products
    for CMTM8 gene

    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
    In Situ Hybridization Assays from
    Advanced Cell Diagnostics
    About This Section

     
     EMD Millipore Custom Antibody & Bulk Services
     EMD Millipore Preclinical / Clinical Development Services
     EMD Millipore Immunoassay Services
     EMD Millipore Target Screening & Profiling Services

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
     Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Phosphatase Activity Assays/Reagents   Browse Recombinant/Natural Proteins  
     Browse OriGene Antibodies   OriGene shRNA RFP for CMTM8  
     OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CMTM8   OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CMTM8  
     OriGene Protein Over-expression Lysate for CMTM8   Browse OriGene Fluorogenic Cell Assay Kits  
     OriGene siRNA for CMTM8   OriGene 3'-UTR Clone for CMTM8  
     OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CMTM8   OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CMTM8  
     Browse OriGene GFP tagged cDNA clones in CMV expression vector   Browse OriGene MicroRNA Expression Plasmids  
     Browse OriGene basic RS shRNAs   Browse OriGene validated miRNA SYBR primer pairs  
     Browse OriGene full length recombinant human proteins expressed in human HEK293 cells   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for CMTM8   OriGene Custom Protein Services for CMTM8  
     OriGene Custom Immunoassay Development  

         		 
     QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat CMTM8
     QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CMTM8
     QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CMTM8
     QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CMTM8
     QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CMTM8
     QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CMTM8
     GenScript Custom Purified and Recombinant Proteins Services for CMTM8 GenScript cDNA clones with any tag delivered in your preferred vector for CMTM8
     GenScript Custom Assay Services for CMTM8 GenScript Custom Superior Antibodies Services for CMTM8
     GenScript Custom overexpressing Cell Line Services for CMTM8 CloneReady with Over 120,000 Genes
     Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
     Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
     Custom Peptide Services
     Search for Antibodies & Assays

     Regulatory tfbs in CMTM8 promoter
     Search Chromatin IP Primers for CMTM8
     RT2 qPCR Primer Assay in human, mouse, rat CMTM8
     Search GNC Networks for CMTM8
     SABiosciences Custom PCR Arrays for CMTM8
     Search Tocris compounds for CMTM8
     Browse Sino Biological Proteins and Antibodies
     cDNA Clones for CMTM8
     Antibodies/Proteins Production Services
     Rabbit Monoclonal Antibody Platform
     Bulk Purchasing
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
     Novus Tissue Slides
     CMTM8 antibodies
     CMTM8 proteins
     CMTM8 lysates
     Search for Antibodies for CMTM8 at Abcam
     See all of Abcam's Antibodies, Kits and Proteins for CMTM8
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins




     CMTM8 Proteins, Antibodies, CLIAs, and ELISAs
     Search LifeMap BioReagents cell lines for CMTM8
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CMTM8
     SwitchGear 3'UTR luciferase reporter plasmids for CMTM8
     SwitchGear Promoter luciferase reporter plasmids for CMTM8
     Search ThermoFisher Antibodies for CMTM8
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CMTM8
           
    GeneCards Homepage - Last full update: 19 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

    View Random Gene

    Category
    VWF
    (GIFTS: 73)
    von Willebrand factor
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 

    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Copyright © 1996-2013 , Weizmann Institute of Science. All Rights Reserved.
    Hot genes      Disease genes      CMTM8 gene at Home site.
    hostname: 356977-web1.xennexinc.com index build: 100 solr: 1.4