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Aliases for CMTM7 Gene

Aliases for CMTM7 Gene

  • CKLF-Like MARVEL Transmembrane Domain Containing 7 2 3
  • CKLFSF7 3 4 6
  • Chemokine-Like Factor Superfamily Member 7 3 4
  • Chemokine-Like Factor Super Family 7 2 3
  • Chemokine-Like Factor Superfamily 7 2 3
  • CKLF-Like MARVEL Transmembrane Domain-Containing Protein 7 3
  • Chemokine-Like Factor Super Family Member 7 Variant 2 3

External Ids for CMTM7 Gene

Previous HGNC Symbols for CMTM7 Gene


Summaries for CMTM7 Gene

Entrez Gene Summary for CMTM7 Gene

  • This gene belongs to the chemokine-like factor gene superfamily, a novel family that is similar to the chemokine and transmembrane 4 superfamilies. This gene is one of several chemokine-like factor genes located in a cluster on chromosome 3. The protein encoded by this gene is highly expressed in leukocytes, but its exact function is unknown. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]

GeneCards Summary for CMTM7 Gene

CMTM7 (CKLF-Like MARVEL Transmembrane Domain Containing 7) is a Protein Coding gene. GO annotations related to this gene include cytokine activity.

No data available for UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CMTM7 Gene

Genomics for CMTM7 Gene

Regulatory Elements for CMTM7 Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for CMTM7 Gene

32,391,671 bp from pter
32,483,067 bp from pter
91,397 bases
Plus strand

Genomic View for CMTM7 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for CMTM7 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CMTM7 Gene

Proteins for CMTM7 Gene

  • Protein details for CMTM7 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    CKLF-like MARVEL transmembrane domain-containing protein 7
    Protein Accession:
    Secondary Accessions:
    • Q5VLK1

    Protein attributes for CMTM7 Gene

    175 amino acids
    Molecular mass:
    18834 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for CMTM7 Gene


neXtProt entry for CMTM7 Gene

Proteomics data for CMTM7 Gene at MOPED

Post-translational modifications for CMTM7 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for CMTM7 Gene

Antibody Products

No data available for DME Specific Peptides for CMTM7 Gene

Domains for CMTM7 Gene

Gene Families for CMTM7 Gene

Protein Domains for CMTM7 Gene


Suggested Antigen Peptide Sequences for CMTM7 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Contains 1 MARVEL domain.
  • Belongs to the chemokine-like factor family.
  • Contains 1 MARVEL domain.
  • Belongs to the chemokine-like factor family.
genes like me logo Genes that share domains with CMTM7: view

Function for CMTM7 Gene

Gene Ontology (GO) - Molecular Function for CMTM7 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005125 cytokine activity IEA --
genes like me logo Genes that share ontologies with CMTM7: view

Phenotypes for CMTM7 Gene

GenomeRNAi human phenotypes for CMTM7:
genes like me logo Genes that share phenotypes with CMTM7: view

Animal Model Products

miRNA for CMTM7 Gene

miRTarBase miRNAs that target CMTM7

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for CMTM7

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Animal Models , Transcription Factor Targets and HOMER Transcription for CMTM7 Gene

Localization for CMTM7 Gene

Subcellular locations from UniProtKB/Swiss-Prot for CMTM7 Gene

Membrane; Multi-pass membrane protein.

Subcellular locations from

Jensen Localization Image for CMTM7 Gene COMPARTMENTS Subcellular localization image for CMTM7 gene
Compartment Confidence
extracellular 3
plasma membrane 3

Gene Ontology (GO) - Cellular Components for CMTM7 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005615 extracellular space IEA --
GO:0016020 membrane IDA 19946888
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with CMTM7: view

Pathways for CMTM7 Gene

SuperPathways for CMTM7 Gene

No Data Available

Interacting Proteins for CMTM7 Gene

STRING Interaction Network Preview (showing 2 interactants - click image to see details)
Selected Interacting proteins: ENSP00000335605 for CMTM7 Gene via STRING

Gene Ontology (GO) - Biological Process for CMTM7 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0002337 B-1a B cell differentiation IEA --
GO:0006935 chemotaxis IEA --
genes like me logo Genes that share ontologies with CMTM7: view

No data available for Pathways by source for CMTM7 Gene

Transcripts for CMTM7 Gene

Unigene Clusters for CMTM7 Gene

CKLF-like MARVEL transmembrane domain containing 7:
Representative Sequences:

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for CMTM7

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for CMTM7 Gene

ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4a · 4b ^ 5 ^ 6a · 6b · 6c
SP1: - -
SP2: -
SP3: - - -
SP4: - - - -

Relevant External Links for CMTM7 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for CMTM7 Gene

mRNA expression in normal human tissues for CMTM7 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for CMTM7 Gene

This gene is overexpressed in Whole Blood (10.8).

Protein differential expression in normal tissues for CMTM7 Gene

This gene is overexpressed in Plasma (50.3).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for CMTM7 Gene

SOURCE GeneReport for Unigene cluster for CMTM7 Gene Hs.440494

mRNA Expression by UniProt/SwissProt for CMTM7 Gene

Tissue specificity: Highly expressed in leukocytes.
genes like me logo Genes that share expressions with CMTM7: view

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for Expression partners for CMTM7 Gene

Orthologs for CMTM7 Gene

This gene was present in the common ancestor of chordates.

Orthologs for CMTM7 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia CMTM7 35
  • 87.55 (n)
  • 84.48 (a)
CMTM7 36
  • 83 (a)
(Canis familiaris)
Mammalia CMTM7 35
  • 86.85 (n)
  • 82.99 (a)
CMTM7 36
  • 83 (a)
(Mus musculus)
Mammalia Cmtm7 35
  • 85.14 (n)
  • 84.94 (a)
Cmtm7 16
Cmtm7 36
  • 83 (a)
(Pan troglodytes)
Mammalia CMTM7 35
  • 99.62 (n)
  • 100 (a)
CMTM7 36
  • 100 (a)
(Rattus norvegicus)
Mammalia Cmtm7 35
  • 84.47 (n)
  • 82.61 (a)
(Monodelphis domestica)
Mammalia CMTM7 36
  • 68 (a)
(Ornithorhynchus anatinus)
Mammalia CMTM7 36
  • 76 (a)
(Gallus gallus)
Aves CMTM7 35
  • 66.48 (n)
  • 63.79 (a)
CMTM7 36
  • 61 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia cmtm7 35
  • 63.84 (n)
  • 58.79 (a)
(Danio rerio)
Actinopterygii cmtm7 35
  • 56.38 (n)
  • 54.36 (a)
cmtm7 36
  • 52 (a)
sea squirt
(Ciona savignyi)
Ascidiacea CSA.146 36
  • 34 (a)
Species with no ortholog for CMTM7:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for CMTM7 Gene

Gene Tree for CMTM7 (if available)
Gene Tree for CMTM7 (if available)

Paralogs for CMTM7 Gene

(1) SIMAP similar genes for CMTM7 Gene using alignment to 4 proteins: Pseudogenes for CMTM7 Gene

genes like me logo Genes that share paralogs with CMTM7: view

No data available for Paralogs for CMTM7 Gene

Variants for CMTM7 Gene

Sequence variations from dbSNP and Humsavar for CMTM7 Gene

SNP ID Clin Chr 03 pos Sequence Context AA Info Type MAF
rs10165 -- 32,454,603(-) TAGAA(C/G)GGATT utr-variant-3-prime
rs164035 -- 32,437,760(-) GTATG(A/C)GCCAC intron-variant
rs164212 -- 32,447,652(-) gaatc(C/T)gtaag intron-variant
rs164218 -- 32,453,362(-) ATTTT(C/G)AGAGA intron-variant
rs164222 -- 32,443,418(-) aataa(A/T)atttg intron-variant

Structural Variations from Database of Genomic Variants (DGV) for CMTM7 Gene

Variant ID Type Subtype PubMed ID
nsv834652 CNV Loss 17160897
nsv518025 CNV Gain 19592680
nsv522856 CNV Gain 19592680

Relevant External Links for CMTM7 Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CMTM7 Gene

Disorders for CMTM7 Gene

Relevant External Links for CMTM7

Genetic Association Database (GAD)
Human Genome Epidemiology (HuGE) Navigator

No disorders were found for CMTM7 Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships and Genatlas for CMTM7 Gene

Publications for CMTM7 Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4
  2. Identification of eight genes encoding chemokine-like factor superfamily members 1-8 (CKLFSF1-8) by in silico cloning and experimental validation. (PMID: 12782130) Han W. … Ma D. (Genomics 2003) 3 4
  3. Genomic variation associated with mortality among adults of European and African ancestry with heart failure: the cohorts for heart and aging research in genomic epidemiology consortium. (PMID: 20400778) Morrison A.C. … Smith N.L. (Circ Cardiovasc Genet 2010) 3 48
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for CMTM7 Gene

Sources for CMTM7 Gene

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