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CMTM7 Gene

protein-coding   GIFtS: 46
GCID: GC03P032409

CKLF-Like MARVEL Transmembrane Domain Containing 7

(Previous names: chemokine-like factor super family 7, chemokine-like factor...)
(Previous symbol: CKLFSF7)
  Search for CMTM7
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
CKLF-Like MARVEL Transmembrane Domain Containing 71 2     Chemokine-Like Factor Superfamily Member 72 3
CKLFSF71 2 3 5     Chemokine-Like Factor Super Family Member 7 Variant 22
Chemokine-Like Factor Super Family 71 2     CKLF-Like MARVEL Transmembrane Domain-Containing Protein 72
Chemokine-Like Factor Superfamily 71 2     

External Ids:    HGNC: 191781   Entrez Gene: 1126162   Ensembl: ENSG000001535517   OMIM: 6078905   UniProtKB: Q96FZ53   

Export aliases for CMTM7 gene to outside databases


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for CMTM7 Gene:
This gene belongs to the chemokine-like factor gene superfamily, a novel family that is similar to the chemokine
and transmembrane 4 superfamilies. This gene is one of several chemokine-like factor genes located in a cluster
on chromosome 3. The protein encoded by this gene is highly expressed in leukocytes, but its exact function is
unknown. Alternatively spliced transcript variants encoding different isoforms have been identified. (provided by
RefSeq, Jul 2008)

GeneCards Summary for CMTM7 Gene:
CMTM7 (CKLF-like MARVEL transmembrane domain containing 7) is a protein-coding gene. GO annotations related to this gene include cytokine activity.




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000003.12  NC_018914.2  NT_022517.19  
Regulatory elements:
   Regulatory transcription factor binding sites in the CMTM7 gene promoter:
         HEN1   AREB6   POU2F1   POU2F1a   AP-4   Pax-4a   c-Ets-1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCMTM7 promoter sequence
   Search Chromatin IP Primers for CMTM7

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat CMTM7


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3p22.3   Ensembl cytogenetic band:  3p22.3   HGNC cytogenetic band: 3p22.2

CMTM7 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CMTM7 gene location

GeneLoc information about chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03P032409:  view genomic region     (about GC identifiers)

Start:
32,433,163 bp from pter      End:
32,524,559 bp from pter
Size:
91,397 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: CKLF7_HUMAN, Q96FZ5 (See protein sequence)
Recommended Name: CKLF-like MARVEL transmembrane domain-containing protein 7  
Size: 175 amino acids; 18834 Da
Secondary accessions: Q5VLK1
Alternative splicing: 2 isoforms:  Q96FZ5-1   Q96FZ5-2   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for CMTM7: NX_Q96FZ5

Explore proteomics data for CMTM7 at MOPED


See CMTM7 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

REFSEQ proteins (2 alternative transcripts): 
NP_612419.1  NP_852137.1  

ENSEMBL proteins: 
 ENSP00000335605   ENSP00000283621   ENSP00000414480   ENSP00000440333   ENSP00000445027  

CMTM7 Human Recombinant Protein Products:

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CMTM7 Assay Products:

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Browse CLIAs at Cloud-Clone Corp.


(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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1 InterPro protein domain:
 IPR008253 Marvel

Graphical View of Domain Structure for InterPro Entry Q96FZ5

ProtoNet protein and cluster: Q96FZ5

1 Blocks protein domain: IPB008253 Marvel

UniProtKB/Swiss-Prot: CKLF7_HUMAN, Q96FZ5
Similarity: Belongs to the chemokine-like factor family
Similarity: Contains 1 MARVEL domain


CMTM7 for domains           About GeneDecksing


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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     Gene Ontology (GO): 1 molecular function term:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005125cytokine activity IEA--
     
CMTM7 for ontologies           About GeneDecksing


Phenotypes:
     1 GenomeRNAi human phenotype for CMTM7:
 Decreased circadian period len 

Animal Models:
   inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for CMTM7
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   genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for CMTM7
   genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for CMTM7

miRNA
Products:
    
miRTarBase miRNAs that target CMTM7:
hsa-mir-124-3p (MIRT022306)

Block miRNA regulation of human, mouse, rat CMTM7 using miScript Target Protectors
6 qRT-PCR Assays for microRNAs that regulate CMTM7:
hsa-miR-544b hsa-miR-182 hsa-miR-16-2* hsa-miR-195* hsa-miR-1271 hsa-miR-96
SwitchGear 3'UTR luciferase reporter plasmidCMTM7 3' UTR sequence
Inhib. RNA
Products:
    
OriGene RNAi products in human, mouse, rat for CMTM7
Predesigned siRNA for gene silencing in human, mouse, rat CMTM7

Gene Editing
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DNA2.0 Custom Protein Engineering Service for CMTM7

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OriGene clones in human, mouse for CMTM7 (see all 14)
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GenScript: all cDNA clones in your preferred vector (see all 2): CMTM7 (NM_138410)
Sino Biological Human cDNA Clone for CMTM7
DNA2.0 Custom Codon Optimized Gene Synthesis Service for CMTM7
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CMTM7

Cell Line
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Browse ESI BIO Cell Lines and PureStem Progenitors for CMTM7 
In Situ Assay
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Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CMTM7


(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Subcellular locations from UniProtKB/Swiss-Prot
CKLF7_HUMAN, Q96FZ5: Membrane; Multi-pass membrane protein
Subcellular locations from COMPARTMENTS: 

CompartmentConfidence
extracellular3
plasma membrane3

Gene Ontology (GO): 3 cellular component terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005615extracellular space IEA--
GO:0016020membrane ----
GO:0016021integral component of membrane IEA--

CMTM7 for ontologies           About GeneDecksing


(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for CMTM7
Interactions:

    Search GeneGlobe Interaction Network for CMTM7

Gene Ontology (GO): 1 biological process term:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0006935chemotaxis IEA--

CMTM7 for ontologies           About GeneDecksing



(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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Browse Small Molecules at EMD Millipore
   Browse drugs & compounds from Enzo Life Sciences
  Browse compounds at ApexBio 

Browse Tocris compounds for CMTM7 (CKLF7)



(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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REFSEQ mRNAs for CMTM7 gene (2 alternative transcripts): 
NM_138410.2  NM_181472.1  

Unigene Cluster for CMTM7:

CKLF-like MARVEL transmembrane domain containing 7
Hs.440494  [show with all ESTs]
Unigene Representative Sequence: AK308878
6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000334983(uc003cey.1 uc003cez.1) ENST00000349718 ENST00000454304
ENST00000465248 ENST00000487007 ENST00000464689
miRNA
Products:
     
Block miRNA regulation of human, mouse, rat CMTM7 using miScript Target Protectors
6 qRT-PCR Assays for microRNAs that regulate CMTM7:
hsa-miR-544b hsa-miR-182 hsa-miR-16-2* hsa-miR-195* hsa-miR-1271 hsa-miR-96
SwitchGear 3'UTR luciferase reporter plasmidCMTM7 3' UTR sequence
Inhib. RNA
Products:
     
OriGene RNAi products in human, mouse, rat for CMTM7
Predesigned siRNA for gene silencing in human, mouse, rat CMTM7
Clone
Products:
     
OriGene clones in human, mouse for CMTM7 (see all 14)
OriGene ORF clones in mouse, rat for CMTM7
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector (see all 2): CMTM7 (NM_138410)
DNA2.0 Custom Codon Optimized Gene Synthesis Service for CMTM7
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CMTM7
Primer
Products:
    
OriGene qPCR primer pairs and template standards for CMTM7
OriGene qSTAR qPCR primer pairs in human, mouse for CMTM7
Pre-validated RT2 qPCR Primer Assay in human, mouse, rat CMTM7
  QuantiTect SYBR Green Assays in human, mouse, rat CMTM7
  QuantiFast Probe-based Assays in human, mouse, rat CMTM7

Additional mRNA sequence: 

AF479263.2 AK308878.1 AY174113.1 BC010116.2 DQ132881.1 

14 DOTS entries:

DT.80101456  DT.100794687  DT.113567  DT.101972499  DT.91752198  DT.120884865  DT.100794690  DT.120884891 
DT.100789839  DT.95168235  DT.95258420  DT.100711974  DT.120884841  DT.439648 

Selected AceView cDNA sequences (see all 123):

CD723512 BE740519 BE622335 AA554328 CA489158 CD674269 AA480075 CR599506 
BM684200 BU155257 AA304308 BU731484 NM_138410 AL832450 AW591933 BM823878 
CR614533 CR594621 AA427707 NM_181472 CR604270 BC010116 CD674360 AF479263 

GeneLoc Exon Structure

5 Alternative Splicing Database (ASD) splice patterns (SP) for CMTM7    About this scheme

ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4a · 4b ^ 5 ^ 6a · 6b · 6c
SP1:                                -     -                           
SP2:                                -                                 
SP3:                          -     -     -                           
SP4:                          -     -     -     -                     
SP5:                                                                  


ECgene alternative splicing isoforms for CMTM7

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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CMTM7 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: --
CMTM7 Expression
About this image


CMTM7 expression in embryonic tissues and stem cells    About this table
Data from LifeMap, the Embryonic Development and Stem Cells Database
 selected tissues (see all 4) fully expand
 
 Inner Cell Mass (Early Embryonic Tissues)    fully expand to see all 2 entries
         Human embryonic stem cells (family)
 
 Kidney (Urinary System)    fully expand to see all 2 entries
         S-shaped Body
 
 Neurons
         Cholinergic Amacrine Cells Inner Nuclear Layer
 
 Eye (Sensory Organs)
         Cholinergic Amacrine Cells Inner Nuclear Layer
CMTM7 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

CMTM7 Protein Expression

SOURCE GeneReport for Unigene cluster: Hs.440494

UniProtKB/Swiss-Prot: CKLF7_HUMAN, Q96FZ5
Tissue specificity: Highly expressed in leukocytes

    Custom PCR Arrays for CMTM7
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QuantiFast Probe-based Assays in human, mouse, rat CMTM7
In Situ
Assay Products:
 

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CMTM7

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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This gene was present in the common ancestor of chordates.

Orthologs for CMTM7 gene from Selected species (see all 13)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
mouse
(Mus musculus)
Mammalia Cmtm71 , 5 CKLF-like MARVEL transmembrane domain containing 71, 5 85.14(n)1
84.94(a)1
  9 (65.13 cM)5
1025451  NM_133978.21  NP_598739.11 
 1147568375 
chicken
(Gallus gallus)
Aves CMTM71 CKLF-like MARVEL transmembrane domain containing 7 66.48(n)
63.79(a)
  420666  NM_001007894.1  NP_001007895.1 
African clawed frog
(Xenopus laevis)
Amphibia BC056111.12   -- 69.91(n)    BC056111.1 
zebrafish
(Danio rerio)
Actinopterygii cmtm71 CKLF-like MARVEL transmembrane domain containing 7 56.38(n)
54.36(a)
  559138  NM_001130114.1  NP_001123586.1 


ENSEMBL Gene Tree for CMTM7 (if available)
TreeFam Gene Tree for CMTM7 (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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Paralogs for CMTM7 gene
1 SIMAP similar gene for CMTM7 using alignment to 4 protein entries:     CKLF7_HUMAN (see all proteins):
CKLFSF7

CMTM7 for paralogs           About GeneDecksing


1 Pseudogenes.org Pseudogene for CMTM7
PGOHUM00000260377


(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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Selected SNPs for CMTM7 (see all 1336)    About this table    
Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 3 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs98394251,2
C,F,A,H--32431201(+) GTTTCA/GCTTTG 2 -- us2k1 tfbs36Minor allele frequency- G:0.17NA WA CSA EA 366
rs1913301461,2
--32431262(+) ACAGTA/GTTGTA 2 -- us2k10--------
rs1824245951,2
C--32431396(+) GATGGA/GGTTTC 2 -- us2k10--------
rs124977191,2
C,F,H--32431420(+) TGCTGG/TTGTCA 2 -- us2k18Minor allele frequency- T:0.06NS EA NA WA 736
rs1436637861,2
C--32431615(+) TTTCC-/TTTTCT
        
TTTTC
2 -- us2k10--------
rs784850771,2
--32431620(+) TTTTCC/TTTTTC 2 -- us2k10--------
rs1874241991,2
--32431678(+) AGTGCA/GGTGGC 2 -- us2k10--------
rs780115591,2
C,F--32431814(+) AAAAGG/AGATAC 2 -- us2k13Minor allele frequency- A:0.04WA NA EA 358
rs716305201,2
C--32431871(+) TTTTTT/-AATTG 2 -- us2k11Minor allele frequency- -:0.50NA 2
rs786821451,2
C,F--32431986(+) TCCAGA/CCTCAG 2 -- us2k13Minor allele frequency- C:0.11WA NA EA 358

HapMap Linkage Disequilibrium report for CMTM7 (32433163 - 32524559 bp)

Structural Variations
     Database of Genomic Variants (DGV) 3 variations for CMTM7:    About this table    
Variant IDTypeSubtypePubMed ID
nsv834652CNV Loss17160897
nsv522856CNV Gain19592680
nsv518025CNV Gain19592680

Site Specific Mutation Identification with PCR Assays
SeqTarget long-range PCR primers for resequencing CMTM7
DNA2.0 Custom Variant and Variant Library Synthesis for CMTM7

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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OMIM gene information: 607890    OMIM disorders: --


CMTM7 for disorders           About GeneDecksing

Genetic Association Database (GAD): CMTM7
Human Genome Epidemiology (HuGE) Navigator: CMTM7 (2 documents)

Export disorders for CMTM7 gene to outside databases

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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PubMed articles for CMTM7 gene integrated from 10 sources:
(articles sorted by number of sources associating them with CMTM7)
    Utopia: connect your pdf to the dynamic
world of online information

  1. Genomic variation associated with mortality among adults of European and African ancestry with heart failure: the cohorts for heart and aging research in genomic epidemiology consortium. (PubMed id 20400778)1, 4 Morrison A.C....Smith N.L. (Circ Cardiovasc Genet 2010)
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
  3. Identification of eight genes encoding chemokine-like factor superfamily members 1-8 (CKLFSF1-8) by in silico cloning and experimental validation. (PubMed id 12782130)1, 2 Han W.... Ma D. (Genomics 2003)
  4. Identification of CMTM7 as a transmembrane linker of BLNK and the B-cell receptor. (PubMed id 22363743)1 Miyazaki A....Kitamura D. (PLoS ONE 2012)
  5. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (amp 2011)
  6. The DNA sequence, annotation and analysis of human chromosome 3. (PubMed id 16641997)2 Muzny D.M....Gibbs R.A. (Nature 2006)
  7. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1 Ota T.... Sugano S. (Nat. Genet. 2004)
  8. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)

(in PubMed, OMIM, and NCBI Bookshelf)
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 ANDOR
Aliases
Free Text  

  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 112616 HGNC: 19178 AceView: CKLFSF7 Ensembl:ENSG00000153551 euGenes: HUgn112616
ECgene: CMTM7 H-InvDB: CMTM7

(According to HUGE)
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  --

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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NameDescription
PharmGKB entry for CMTM7 Pharmacogenomics, SNPs, Pathways

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
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Patent Information for CMTM7 gene:
Search GeneIP for patents involving CMTM7

GeneCards and IP:
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(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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 OriGene Antibodies for CMTM7   OriGene RNAi products in human, mouse, rat for CMTM7  
 OriGene qPCR primer pairs and template standards for CMTM7   OriGene Protein Over-expression Lysate for CMTM7  
 OriGene Custom Mass Spec   OriGene clones in human, mouse for CMTM7  
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 OriGene Custom Antibody Services for CMTM7   OriGene Custom Protein Services for CMTM7  

 
 
 Block miRNA regulation of human, mouse, rat CMTM7 using miScript Target Protectors SeqTarget long-range PCR primers for resequencing CMTM7
 DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat CMTM7 Predesigned siRNA for gene silencing in human, mouse, rat CMTM7
 QuantiFast Probe-based Assays in human, mouse, rat CMTM7 QuantiTect SYBR Green Assays in human, mouse, rat CMTM7
 Custom PCR Arrays for CMTM7 Search Chromatin IP Primers for CMTM7
 Pre-validated RT2 qPCR Primer Assay in human, mouse, rat CMTM7  Search GeneGlobe Interaction Network for CMTM7
 Regulatory tfbs in CMTM7 promoter
 GenScript Custom Purified and Recombinant Proteins Services for CMTM7 GenScript cDNA clones with any tag delivered in your preferred vector for CMTM7
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 Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
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 Search Tocris compounds for CMTM7 (CKLF7)
 Browse Sino Biological Proteins
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 Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

 Novus Tissue Slides
 CMTM7 antibodies
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 Antibodies for CMTM7
 See all of Abcam's Antibodies, Kits and Proteins for CMTM7
 Custom Antibody / Protein Production Service
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 Abcam protocols and scientific support
 Browse ProSpec Recombinant Proteins
 Browse Proteins at Cloud-Clone Corp.
 Browse Antibodies at Cloud-Clone Corp.
 Browse ELISAs at Cloud-Clone Corp.
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 Browse ESI BIO Cell Lines and PureStem Progenitors for CMTM7
 Gene Synthesis
 Protein Engineering
 Variant Library Synthesis
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 Protein Production and Purification
 Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CMTM7
 SwitchGear 3'UTR luciferase reporter plasmids for CMTM7
 SwitchGear Promoter luciferase reporter plasmids for CMTM7
 ThermoFisher Antibody for CMTM7
 Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CMTM7
 inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for CMTM7
 inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for CMTM7
 LSBio Antibodies in human, mouse, rat for CMTM7
Customized transgenic rodents for:
 Humanization
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 Browse compounds at ApexBio
       
GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014

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