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Aliases for CMSS1 Gene

Aliases for CMSS1 Gene

  • Cms1 Ribosomal Small Subunit Homolog (Yeast) 2 3 5
  • C3orf26 3 4
  • Cms1 Ribosomal Small Subunit Homolog 4
  • Chromosome 3 Open Reading Frame 26 2
  • Protein CMSS1 3

External Ids for CMSS1 Gene

Previous HGNC Symbols for CMSS1 Gene

  • C3orf26

Previous GeneCards Identifiers for CMSS1 Gene

  • GC03P099539

Summaries for CMSS1 Gene

GeneCards Summary for CMSS1 Gene

CMSS1 (Cms1 Ribosomal Small Subunit Homolog (Yeast)) is a Protein Coding gene. Diseases associated with CMSS1 include Refractive Error. GO annotations related to this gene include nucleic acid binding and poly(A) RNA binding.

Additional gene information for CMSS1 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CMSS1 Gene

Genomics for CMSS1 Gene

Regulatory Elements for CMSS1 Gene

Enhancers for CMSS1 Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH03H100072 1.5 Ensembl ENCODE dbSUPER 18.9 +257.3 257312 5 PKNOX1 FOXA2 MLX ARID4B TCF12 SLC30A9 ZNF766 FOS RUNX3 NFYC CMSS1 FILIP1L TBC1D23 TMEM30CP GC03M100078 PIR33357
GH03H100039 1.9 FANTOM5 Ensembl ENCODE dbSUPER 12.4 +226.8 226756 9 PKNOX1 FOXA2 SIN3A FEZF1 YY1 FOS ATF7 RUNX3 JUNB TSHZ1 FILIP1L TBC1D23 CMSS1 TMEM45A PIR33357 GC03M100040
GH03H100089 1.4 Ensembl ENCODE dbSUPER 12.2 +272.4 272409 1 HDAC1 ATF1 TBL1XR1 RAD21 CHAMP1 TCF12 ZNF766 GATA2 EGR1 FOS FILIP1L CMSS1 GC03M100078 GC03M100108
GH03H099858 1.5 FANTOM5 Ensembl ENCODE dbSUPER 10.2 +43.5 43450 5 JUN BATF BRCA1 GATA3 POLR2A FOS RCOR1 RUNX3 MAFK PAF1 FILIP1L TBC1D23 CMSS1 TOMM70 PIR40829 GC03M099852
GH03H100063 1.4 Ensembl ENCODE dbSUPER 10.7 +246.7 246714 1 ELF3 FOXA2 MLX ARID4B THRB ZSCAN9 RAD21 RARA SLC30A9 CREM FILIP1L TBC1D23 CMSS1 PIR33357 GC03M100078
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around CMSS1 on UCSC Golden Path with GeneCards custom track

Promoters for CMSS1 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters
ENSR00000155524 66 1801 HDGF PKNOX1 ARNT ARID4B SIN3A FEZF1 DMAP1 ZNF2 YY1 SLC30A9

Genomic Location for CMSS1 Gene

Chromosome:
3
Start:
99,817,834 bp from pter
End:
100,181,732 bp from pter
Size:
363,899 bases
Orientation:
Plus strand

Genomic View for CMSS1 Gene

Genes around CMSS1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CMSS1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CMSS1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CMSS1 Gene

Proteins for CMSS1 Gene

  • Protein details for CMSS1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9BQ75-CMS1_HUMAN
    Recommended name:
    Protein CMSS1
    Protein Accession:
    Q9BQ75
    Secondary Accessions:
    • A8K5S7
    • B4DUM1
    • E9PHS3

    Protein attributes for CMSS1 Gene

    Size:
    279 amino acids
    Molecular mass:
    31884 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for CMSS1 Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for CMSS1 Gene

Post-translational modifications for CMSS1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for CMSS1 Gene

No data available for DME Specific Peptides for CMSS1 Gene

Domains & Families for CMSS1 Gene

Gene Families for CMSS1 Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for CMSS1 Gene

InterPro:
ProtoNet:

Graphical View of Domain Structure for InterPro Entry

Q9BQ75

UniProtKB/Swiss-Prot:

CMS1_HUMAN :
  • Belongs to the CMS1 family.
Family:
  • Belongs to the CMS1 family.
genes like me logo Genes that share domains with CMSS1: view

No data available for Suggested Antigen Peptide Sequences for CMSS1 Gene

Function for CMSS1 Gene

Phenotypes From GWAS Catalog for CMSS1 Gene

Gene Ontology (GO) - Molecular Function for CMSS1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0003723 RNA binding IDA 22658674
genes like me logo Genes that share ontologies with CMSS1: view
genes like me logo Genes that share phenotypes with CMSS1: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

Clone Products

  • Applied Biological Materials Clones for CMSS1
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for CMSS1 Gene

Localization for CMSS1 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for CMSS1 gene
Compartment Confidence
nucleus 5
plasma membrane 2
mitochondrion 2
cytosol 1

Subcellular locations from the

Human Protein Atlas (HPA)
  • Mitochondria (2)
  • Nuclear membrane (2)
  • Nucleoli (2)
  • Nucleus (2)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for CMSS1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IBA --
GO:0030686 90S preribosome IBA --
genes like me logo Genes that share ontologies with CMSS1: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for CMSS1 Gene

Pathways & Interactions for CMSS1 Gene

SuperPathways for CMSS1 Gene

No Data Available

Gene Ontology (GO) - Biological Process for CMSS1 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for CMSS1 Gene

Drugs & Compounds for CMSS1 Gene

No Compound Related Data Available

Transcripts for CMSS1 Gene

Unigene Clusters for CMSS1 Gene

Cms1 ribosomal small subunit homolog (yeast):
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

Clone Products

  • Applied Biological Materials Clones for CMSS1
  • Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more

Alternative Splicing Database (ASD) splice patterns (SP) for CMSS1 Gene

No ASD Table

Relevant External Links for CMSS1 Gene

GeneLoc Exon Structure for
CMSS1
ECgene alternative splicing isoforms for
CMSS1

Expression for CMSS1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for CMSS1 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for CMSS1 Gene

This gene is overexpressed in Lung (29.9), Esophagus (19.7), and Kidney (7.2).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, MaxQB, and MOPED for CMSS1 Gene



Protein tissue co-expression partners for CMSS1 Gene

NURSA nuclear receptor signaling pathways regulating expression of CMSS1 Gene:

CMSS1

SOURCE GeneReport for Unigene cluster for CMSS1 Gene:

Hs.581320

Evidence on tissue expression from TISSUES for CMSS1 Gene

  • Nervous system(4.4)
  • Muscle(4.3)
  • Lung(4.2)
genes like me logo Genes that share expression patterns with CMSS1: view

Primer Products

No data available for mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for CMSS1 Gene

Orthologs for CMSS1 Gene

This gene was present in the common ancestor of chordates.

Orthologs for CMSS1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia CMSS1 33 34
  • 99.16 (n)
dog
(Canis familiaris)
Mammalia CMSS1 33 34
  • 90.68 (n)
cow
(Bos Taurus)
Mammalia CMSS1 33 34
  • 88.89 (n)
mouse
(Mus musculus)
Mammalia Cmss1 33 16 34
  • 86.3 (n)
rat
(Rattus norvegicus)
Mammalia Cmss1 33
  • 84.97 (n)
platypus
(Ornithorhynchus anatinus)
Mammalia CMSS1 34
  • 71 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia CMSS1 34
  • 70 (a)
OneToOne
chicken
(Gallus gallus)
Aves C1H3ORF26 33
  • 68.43 (n)
CMSS1 34
  • 67 (a)
OneToOne
lizard
(Anolis carolinensis)
Reptilia CMSS1 34
  • 60 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia cmss1 33
  • 63.08 (n)
Str.1566 33
African clawed frog
(Xenopus laevis)
Amphibia Xl.5091 33
zebrafish
(Danio rerio)
Actinopterygii cmss1 33 34
  • 57.97 (n)
sea squirt
(Ciona savignyi)
Ascidiacea -- 34
  • 41 (a)
OneToOne
Species where no ortholog for CMSS1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for CMSS1 Gene

ENSEMBL:
Gene Tree for CMSS1 (if available)
TreeFam:
Gene Tree for CMSS1 (if available)

Paralogs for CMSS1 Gene

Pseudogenes.org Pseudogenes for CMSS1 Gene

genes like me logo Genes that share paralogs with CMSS1: view

No data available for Paralogs for CMSS1 Gene

Variants for CMSS1 Gene

Sequence variations from dbSNP and Humsavar for CMSS1 Gene

SNP ID Clin Chr 03 pos Sequence Context AA Info Type
rs1000004816 -- 99,904,708(+) GTAGC(A/G)ACTAC intron-variant
rs1000048422 -- 100,027,567(+) TCCCA(C/T)ATGTA intron-variant
rs1000049619 -- 99,833,364(+) GCAAT(C/T)TAGAA intron-variant
rs1000053667 -- 99,889,444(+) CTTTC(A/C)GCTTT intron-variant
rs1000054268 -- 99,890,725(+) AATCC(A/G)CTGTT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for CMSS1 Gene

Variant ID Type Subtype PubMed ID
dgv4829n100 CNV loss 25217958
dgv818n67 CNV loss 20364138
dgv8475n54 CNV gain+loss 21841781
dgv916e214 CNV loss 21293372
esv1177720 CNV insertion 17803354
esv1440096 CNV insertion 17803354
esv2332259 CNV deletion 18987734
esv2507771 CNV insertion 19546169
esv26006 CNV loss 19812545
esv2661948 CNV deletion 23128226
esv2663491 CNV deletion 23128226
esv2668597 CNV deletion 23128226
esv2670786 CNV deletion 23128226
esv2671411 CNV deletion 23128226
esv2725686 CNV deletion 23290073
esv2725687 CNV deletion 23290073
esv2725688 CNV deletion 23290073
esv2725689 CNV deletion 23290073
esv2725690 CNV deletion 23290073
esv2725691 CNV deletion 23290073
esv2725692 CNV deletion 23290073
esv2835236 CNV deletion 24192839
esv2835347 CNV deletion 24192839
esv2945 CNV loss 18987735
esv3325883 CNV duplication 20981092
esv3433874 CNV insertion 20981092
esv3562278 CNV deletion 23714750
esv3562279 CNV deletion 23714750
esv3597160 CNV loss 21293372
esv3597161 CNV loss 21293372
esv3597163 CNV loss 21293372
esv3597164 CNV loss 21293372
esv4340 CNV loss 18987735
esv987776 CNV deletion 20482838
esv988265 CNV deletion 20482838
esv998785 CNV loss 20482838
nsv1109534 CNV deletion 24896259
nsv1117011 CNV deletion 24896259
nsv1131715 CNV deletion 24896259
nsv3918 CNV insertion 18451855
nsv3919 CNV insertion 18451855
nsv475174 CNV novel sequence insertion 20440878
nsv478047 CNV novel sequence insertion 20440878
nsv591147 CNV loss 21841781
nsv591148 CNV loss 21841781
nsv822194 CNV loss 20364138
nsv822197 CNV loss 20364138
nsv954339 CNV deletion 24416366
nsv954357 CNV deletion 24416366
nsv999332 CNV loss 25217958

Variation tolerance for CMSS1 Gene

Residual Variation Intolerance Score: 85.8% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 1.82; 34.29% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for CMSS1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
CMSS1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CMSS1 Gene

Disorders for CMSS1 Gene

MalaCards: The human disease database

(1) MalaCards diseases for CMSS1 Gene - From: DISEASES and GeneCards

Disorder Aliases PubMed IDs
refractive error
  • refractive errors
- elite association - COSMIC cancer census association via MalaCards
Search CMSS1 in MalaCards View complete list of genes associated with diseases

Relevant External Links for CMSS1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
CMSS1
genes like me logo Genes that share disorders with CMSS1: view

No data available for UniProtKB/Swiss-Prot and Genatlas for CMSS1 Gene

Publications for CMSS1 Gene

  1. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 60
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 60
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 2 3 60
  4. Architecture of the human interactome defines protein communities and disease networks. (PMID: 28514442) Huttlin EL … Harper JW (Nature 2017) 3 60
  5. Defining the Protein-Protein Interaction Network of the Human Protein Tyrosine Phosphatase Family. (PMID: 27432908) Li X … Wang W (Molecular & cellular proteomics : MCP 2016) 3 60

Products for CMSS1 Gene

Sources for CMSS1 Gene

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