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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

CMPK2 Gene

protein-coding   GIFtS: 49
GCID: GC02M006980

cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial
 Explore 3 diseases affiliated with
CMPK2 via
MalaCards
our new
 Human Malady Compendium 
Biological research products
for CMPK2    

Aliases
for CMPK2 gene

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section
Aliases
Cytidine Monophosphate (UMP-CMP) Kinase 2, Mitochondrial1 2     Mitochondrial UMP-CMP Kinase2
TYKi1 2     Thymidine Monophosphate Kinase 22
UMP-CMPK21 2     Thymidylate Kinase Family LPS-Inducible Member2
TMPK22     UMP-CMP Kinase 2, Mitochondrial2
Cytidylate Kinase 22     EC 2.7.4.143

External Ids:    HGNC: 270151   Entrez Gene: 1296072   Ensembl: ENSG000001343267   OMIM: 6117875   UniProtKB: Q5EBM03   

Export aliases for CMPK2 gene to outside databases

Previous GC identifers: GC02M006897 GC02M006834


Summaries
for CMPK2 gene

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section
Entrez Gene summary for CMPK2:
This gene encodes one of the enzymes in the nucleotide synthesis salvage pathway that may participate in terminal
differentiation of monocytic cells. Multiple transcript variants encoding different isoforms have been found for this
gene. (provided by RefSeq, Feb 2012)

UniProtKB/Swiss-Prot: CMPK2_HUMAN, Q5EBM0
Function: May participate in dUTP and dCTP synthesis in mitochondria. Is able to phosphorylate dUMP, dCMP, CMP, UMP and
monophosphates of the pyrimidine nucleoside analogs ddC, dFdC, araC, BVDU and FdUrd with ATP as phosphate donor.
Efficacy is highest for dUMP followed by dCMP; CMP and UMP are poor substrates. May be involved in mtDNA depletion
caused by long term treatment with ddC or other pyrimidine analogs




Genomic Views
for CMPK2 gene

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000002.11  NC_018913.1  NT_005334.16  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the CMPK2 gene promoter:
         NF-1   NF-1/L   Pax-5   STAT5A   NF-kappaB   c-Ets-1   AREB6   HEN1   Sox9   NF-kappaB1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmid: CMPK2 promoter sequence
   Search SABiosciences Chromatin IP Primers for CMPK2

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CMPK2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 2p25.2   Ensembl cytogenetic band:  2p25.2   HGNC cytogenetic band: 2p25.2

CMPK2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CMPK2 gene location

GeneLoc information about chromosome 2         GeneLoc Exon Structure

GeneLoc location for GC02M006980:  view genomic region     (about GC identifiers)

Start:
 6,980,701 bp from pter      End:
 7,006,766 bp from pter
Size:
 26,066 bases      Orientation:
 minus strand

Proteins
for CMPK2 gene

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section
UniProtKB/Swiss-Prot: CMPK2_HUMAN, Q5EBM0 (See protein sequence)
Recommended Name: UMP-CMP kinase 2, mitochondrial precursor  
Size: 449 amino acids; 49448 Da
Subcellular location: Mitochondrion
Secondary accessions: A2RUB0 A5D8T2 B7ZM18 Q6ZRU2 Q96AL8
Alternative splicing: 4 isoforms:  Q5EBM0-1   Q5EBM0-2   Q5EBM0-3   Q5EBM0-4   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for CMPK2: NX_Q5EBM0

CMPK2 Protein expression data from MOPED and PaxDb:    About this image 

Estimated protein expression log10 (pmol).

REFSEQ proteins (3 alternative transcripts): 
NP_001243406.1  NP_001243407.1  NP_997198.2  

ENSEMBL proteins: 
 ENSP00000256722   ENSP00000384915   ENSP00000396385  

Human Recombinant Protein Products: 
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Novus Biologicals CMPK2 Protein
Novus Biologicals CMPK2 Lysate
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Browse ProSpec Recombinant Proteins
Uscn Proteins for CMPK2

Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005634nucleus IDA--
GO:0005730NOT nucleolus IDA--
GO:0005739mitochondrion IDA--


CMPK2 for ontologies           About GeneDecksing



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ThermoFisher Antibody for CMPK2

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Uscn ELISAs and CLIAs for CMPK2

Protein Domains /
Families
for CMPK2 gene

(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section
CMPK2 for domains           About GeneDecksing

1 InterPro domain/family:
 IPR014505 UMP-CMP_kinase_mit

Graphical View of Domain Structure for InterPro Entry Q5EBM0

ProtoNet protein and cluster: Q5EBM0

1 Blocks protein family: IPB000062 Thymidylate kinase

UniProtKB/Swiss-Prot: CMPK2_HUMAN, Q5EBM0
Similarity: Belongs to the thymidylate kinase family


Function
for CMPK2 gene

(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section
Function Summary:

     UniProtKB/Swiss-Prot: CMPK2_HUMAN, Q5EBM0
Function: May participate in dUTP and dCTP synthesis in mitochondria. Is able to phosphorylate dUMP, dCMP, CMP, UMP and
monophosphates of the pyrimidine nucleoside analogs ddC, dFdC, araC, BVDU and FdUrd with ATP as phosphate donor.
Efficacy is highest for dUMP followed by dCMP; CMP and UMP are poor substrates. May be involved in mtDNA depletion
caused by long term treatment with ddC or other pyrimidine analogs
Catalytic activity: ATP + (d)CMP = ADP + (d)CDP
Biophysicochemical properties: Kinetic parameters: KM=3.09 mM for CMP; KM=6.3 mM for UMP; KM=1.31 mM for dCMP; KM=0.1
mM for dUMP; Vmax=1.64 umol/min/mg enzyme towards CMP; Vmax=0.19 umol/min/mg enzyme towards UMP; Vmax=1.77 umol/min/mg
enzyme towards dCMP; Vmax=0.48 umol/min/mg enzyme towards dUMP;

Enzyme Number (IUBMB): EC 2.7.4.141

miRNA
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QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat CMPK2
6 QIAGEN miScript miRNA Assays for microRNAs that regulate CMPK2:
hsa-miR-374a* hsa-miR-3658 hsa-miR-944 hsa-miR-519c-3p hsa-miR-519a hsa-miR-519b-3p
SwitchGear 3'UTR luciferase reporter plasmid: CMPK2 3' UTR sequence
Inhib. RNA
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OriGene siRNA: CMPK2
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Gene Editing
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Clone
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Cell Line
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In Situ Assay
Products:   
 		Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CMPK2

Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0004127cytidylate kinase activity IDA17999954
GO:0004798thymidylate kinase activity IEA--
GO:0005524ATP binding IEA--
GO:0033862UMP kinase activity IDA17999954


CMPK2 for ontologies           About GeneDecksing



Pathways & Interactions
for CMPK2 gene

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Unified GeneCards pathways  About this table 
See pathways by source

Super-pathwaycontained gene-specific pathways
1pyrimidine ribonucleotides interconversion
pyrimidine ribonucleotides interconversion1.00
pyrimidine deoxyribonucleotides de novo biosynthesis I0.50
pyrimidine ribonucleotides de novo biosynthesis0.88
2Metabolism
Metabolic pathways0.38
3Purine metabolism
Pyrimidine metabolism0.38

Pathway sources
See GeneCards unified pathways
Show all pathways


3 BioSystems Pathways for CMPK2 
    pyrimidine ribonucleotides de novo biosynthesis
pyrimidine ribonucleotides interconversion
pyrimidine deoxyribonucleotides de novo biosynthesis I


2         Kegg Pathways  (Kegg details for CMPK2):
    Pyrimidine metabolism
Metabolic pathways


CMPK2 for pathways           About GeneDecksing

Interactions:

    Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CMPK2

STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

5/33 Interacting proteins for CMPK2 (Q5EBM03 ENSP000002567224) via UniProtKB, MINT, STRING, and/or I2D (see all 33)
InteractantInteraction Details
GeneCardExternal ID(s)
GABARAPL1Q9H0R83I2D: score=1 
AK3ENSP000003712304STRING: ENSP00000371230
DCKENSP000002866484STRING: ENSP00000286648
DCTDENSP000003495764STRING: ENSP00000349576
ITPAENSP000003694564STRING: ENSP00000369456
About this table

Gene Ontology (GO): 4 biological process terms (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0006221pyrimidine nucleotide biosynthetic process ----
GO:0006227dUDP biosynthetic process IEA--
GO:0006233dTDP biosynthetic process IEA--
GO:0071222cellular response to lipopolysaccharide IEA--


CMPK2 for ontologies           About GeneDecksing



Drugs & Compounds
for CMPK2 gene

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section
Browse Small Molecules at EMD Millipore
Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for CMPK2

9 HMDB Compounds for CMPK2    About this table
CompoundSynonyms CAS #PubMed Ids
ADPadenosindiphosphorsaeure (see all 8)58-64-0--
Adenosine triphosphate5'-(tetrahydrogen triphosphate) Adenosine (see all 24)56-65-5--
CDPCDP (see all 3)63-38-7--
Cytidine monophosphate5'-CMP (see all 14)63-37-6--
Ergocalciferol(+)-Vitamin D2 (see all 72)50-14-6--
Uridine 5'-diphosphate5'-UDP (see all 9)58-98-0--
Uridine 5'-monophosphate5'-UMP (see all 12)58-97-9--
dCDP2'-Deoxycytidine 5'-diphosphate (see all 13)800-73-7--
dCMP2'-Deoxycytidine 5'-monophosphate (see all 12)1032-65-1--
Search CenterWatch for drugs/clinical trials and news about CMPK2 

Transcripts
for CMPK2 gene

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section
REFSEQ mRNAs for CMPK2 gene (3 alternative transcripts): 
NM_001256477.1  NM_001256478.1  NM_207315.3  

Unigene Cluster for CMPK2:

Cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial
Hs.7155  [show with all ESTs]
Unigene Representative Sequence: NM_207315
7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
ENST00000256722(uc002qyo.3) ENST00000478738 ENST00000491738(uc002qyn.1)
ENST00000465619 ENST00000404168(uc010ewv.3) ENST00000470479 ENST00000458098(uc010yis.1)


miRNA
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QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat CMPK2
6 QIAGEN miScript miRNA Assays for microRNAs that regulate CMPK2:
hsa-miR-374a* hsa-miR-3658 hsa-miR-944 hsa-miR-519c-3p hsa-miR-519a hsa-miR-519b-3p
SwitchGear 3'UTR luciferase reporter plasmid: CMPK2 3' UTR sequence
Inhib. RNA
Products:     		Browse for Gene Knock-down Tools from EMD Millipore
OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CMPK2 (see all 4)
OriGene shRNA RFP: CMPK2
OriGene siRNA: CMPK2
QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CMPK2
Clone
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Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CMPK2 
Primer
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  QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CMPK2
  QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CMPK2

Additional cDNA sequence: 

AK308509.1 BC016969.1 BC089425.1 BC132821.1 BC141802.1 BC144202.1 NR_046236.1 

5 DOTS entries:

DT.99931877  DT.453828  DT.95163235  DT.120968148  DT.100648168 

24/105 AceView cDNA sequences (see all 105):

BM819858 BG778349 BX421924 AA211082 CR623316 BC016969 BE748211 BX463706 
BG776607 R50519 BX452339 AW512889 AA134487 NM_207315 N63887 BG547557 
BG501398 AW452347 BG497758 BI818166 BE748510 AW152544 BU070188 CB114648 

GeneLoc Exon Structure


Expression
for CMPK2 gene

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

CMPK2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: AATAAACTTT

Microarray
RNAseq (Illumina Body Map)
(100×FPKM)½
SAGE (Serial Analysis of Gene Expression)
About this image

CMPK2 expression in embryonic tissues and stem cells
Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
1 LifeMap In Vivo Development Anatomical Compartment/Cell 
Tissue Anatomical Compartment CellCategory (developmental path)
BrainBlood Brain BarrierAdult Endothelial CellsBlood Brain Barrier, Endothelium
Expression: Positive    Negative     Selective marker
Experimental details: Curated     Microarrays     In-situ hybridization

See CMPK2 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for CMPK2

SOURCE GeneReport for Unigene cluster: Hs.7155

UniProtKB/Swiss-Prot: CMPK2_HUMAN, Q5EBM0
Tissue specificity: Among all investigated tumors, leukemia cells show the most abundant expression

    SABiosciences Custom PCR Arrays for CMPK2
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In Situ
Assay Products: 
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Orthologs
for CMPK2 gene

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section
This gene was present in the common ancestor of chordates.

Orthologs for CMPK2 gene from 5/14 species (see all 14)    About this table
Organism Taxonomic
classification		 Gene Description Human
Similarity		 Orthology
Type		 Details
mouse
(Mus musculus)		 Mammalia Cmpk21 , 5 cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial1, 5 79.86(n)1
76.85(a)1		   12 (9.69 cM)5
221691  NM_020557.41  NP_065582.31 
 264692155 
chicken
(Gallus gallus)		 Aves CMPK21 cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial 67.64(n)
65.83(a)		   421921  XM_419937.3  XP_419937.3 
lizard
(Anolis carolinensis)		 Reptilia CMPK26
 --
 69(a)
 1 ↔ 1
 1(150144151-150154790)
African clawed frog
(Xenopus laevis)		 Amphibia Xl.188812 Xenopus laevis transcribed sequence with weak similarity more 76.82(n)    BI447531.1 
zebrafish
(Danio rerio)		 Actinopterygii cmpk21 cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial 52.16(n)
46.69(a)		   570478  XM_693963.4  XP_699055.4 


ENSEMBL Gene Tree for CMPK2 (if available)
TreeFam Gene Tree for CMPK2 (if available) 

Paralogs
for CMPK2 gene

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
  --

Genomic Variants
for CMPK2 gene

(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

10/427 NCBI SNPs in CMPK2 are shown (see all 427)     About this table
Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance		Chr 2 posSequence#AA
Chg		TypeMore#Allele
freq		PopTotal
sample		More
----------
rs1831895981,2
--6980235(+) TATCTC/TTTGCC 1 -- ds50010--------
rs745873841,2
--6980338(+) CAGTAG/TGCAGT 1 -- ds50010--------
rs1878055491,2
--6980357(+) AAAGAG/TCAAGG 1 -- ds50010--------
rs1480141511,2
--6980380(+) TTCCCA/GTATGT 1 -- ds50010--------
rs1929375671,2
--6980406(+) TCCACC/TTTAAA 1 -- ds50010--------
rs1424899711,2
--6980423(+) TCACCA/GAGATA 1 -- ds50010--------
rs1841728961,2
--6980425(+) ACCGAA/GATATA 1 -- ds50010--------
rs769237851,2
F,--6980446(+) GTGGGG/TGTGGT 1 -- ds50011Minor allele frequency- T:0.10EA 120
rs1446492491,2
--6980467(+) ATGAAC/TGGAAT 1 -- ds50010--------
rs126178151,2
C,F,H,--6980931(+) AACTGG/TGCCAG 1 -- int113Minor allele frequency- T:0.09NS EA NA 1938

HapMap Linkage Disequilibrium report for CMPK2 (6980701 - 7006766 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
      Database of Genomic Variants (DGV) variations for CMPK2: --

SABiosciences Cancer Mutation PCR Assays
QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CMPK2
DNA2.0 Custom Variant and Variant Library Synthesis for CMPK2

Disorders / Diseases
for CMPK2 gene

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section
CMPK2 for disorders           About GeneDecksing

OMIM gene information: 611787    OMIM disorders: --

3 diseases for CMPK2:    About MalaCards
relapsing-remitting multiple sclerosis    multiple sclerosis    leukemia

Human Genome Epidemiology (HuGE) Navigator: CMPK2 (1 document)

Export disorders for CMPK2 gene to outside databases

Publications
for CMPK2 gene

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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PubMed articles for CMPK2 gene integrated from 9 sources:
(articles sorted by number of sources associating them with CMPK2)		    Utopia: connect your pdf to the dynamic
world of online information

  1. Human UMP-CMP kinase 2, a novel nucleoside monophosphate kinase localized in mitochondria. (PubMed id 17999954)1, 2, 3 Xu Y.... Karlsson A. (2008)
  2. Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
  3. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
  4. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1 Rose J.E....Uhl G.R. (2010)
  5. Identification of a putative human mitochondrial thymidine monophosphate kinase associated with monocytic/macrophage terminal differentiation. (PubMed id 18498354)1 Chen Y.L....Chang Z.F. (2008)
  6. Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (2008)
  7. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
  8. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
  9. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)2 Ota T.... Sugano S. (2004)
  10. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)

External Searches for CMPK2 gene

(in PubMed, OMIM, and NCBI Bookshelf)
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Genome Databases showing CMPK2 gene

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 129607 HGNC: 27015 AceView: LOC129607 Ensembl:ENSG00000134326 euGenes: HUgn129607
ECgene: CMPK2 Kegg: 129607 H-InvDB: CMPK2

Other Databases showing CMPK2 gene

(According to HUGE)
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Specialized Databases showing CMPK2 gene

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
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NameDescription
PharmGKB entry for CMPK2 Pharmacogenomics, SNPs, Pathways

Intellectual Property
for CMPK2 gene

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
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Patent Information for CMPK2 gene:
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