Aliases for CMPK1 Gene
External Ids for CMPK1 Gene
Previous HGNC Symbols for CMPK1 Gene
Previous GeneCards Identifiers for CMPK1 Gene
This gene encodes one of the enzymes required for cellular nucleic acid biosynthesis. This enzyme catalyzes the transfer of a phosphate group from ATP to CMP, UMP, or dCMP, to form the corresponding diphosphate nucleotide. Alternate splicing results in both coding and non-coding transcript variants. [provided by RefSeq, Feb 2012]
GeneCards Summary for CMPK1 Gene
CMPK1 (Cytidine Monophosphate (UMP-CMP) Kinase 1, Cytosolic) is a Protein Coding gene. Diseases associated with CMPK1 include duodenitis and tonsillitis. Among its related pathways are Metabolism and Purine metabolism. GO annotations related to this gene include kinase activity and nucleobase-containing compound kinase activity. An important paralog of this gene is AK1.
UniProtKB/Swiss-Prot for CMPK1 Gene
Catalyzes the phosphorylation of pyrimidine nucleoside monophosphates at the expense of ATP. Plays an important role in de novo pyrimidine nucleotide biosynthesis. Has preference for UMP and CMP as phosphate acceptors. Also displays broad nucleoside diphosphate kinase activity.