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CMC2 Gene

protein-coding   GIFtS: 42
GCID: GC16M081010

C-X(9)-C Motif Containing 2

(Previous names: chromosome 16 open reading frame 61, COX assembly mitochondrial...)
(Previous symbol: C16orf61)
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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This gene clusters with an RNA gene
Subcategory (RNA class): antisense

Quality score for the ORGUL clustered with this gene is 3

Aliases
C-X(9)-C Motif Containing 21 2
C16orf611 2 3
Chromosome 16 Open Reading Frame 611
COX Assembly Mitochondrial Protein 2 Homolog (S. Cerevisiae)1
2310061C15Rik2
COX Assembly Mitochondrial Protein 2 Homolog2

External Ids:    HGNC: 244471   Entrez Gene: 569422   Ensembl: ENSG000001031217   UniProtKB: Q9NRP23   
ORGUL members:         

Export aliases for CMC2 gene to outside databases


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for CMC2 Gene:
CMC2 (C-x(9)-C motif containing 2) is a protein-coding gene.

UniProtKB/Swiss-Prot: COXM2_HUMAN, Q9NRP2
Function: May be involved in cytochrome c oxidase biogenesis (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000016.9  NT_010498.16  NC_018927.2  
Regulatory elements:
   Search for regulatory transcription factor binding sites for CMC2
         Other transcription factors

Browse SwitchGear Promoter luciferase reporter plasmids
   Search Chromatin IP Primers for CMC2

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat CMC2


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 16q23.2   Ensembl cytogenetic band:  16q23.2   HGNC cytogenetic band: 16q23.2

CMC2 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CMC2 gene location

GeneLoc information about chromosome 16         GeneLoc Exon Structure

GeneLoc location for GC16M081010:  view genomic region     (about GC identifiers)

Start:
81,009,698 bp from pter      End:
81,053,875 bp from pter
Size:
44,178 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: COXM2_HUMAN, Q9NRP2 (See protein sequence)
Recommended Name: COX assembly mitochondrial protein 2 homolog  
Size: 79 amino acids; 9460 Da
Secondary accessions: D3DUK6

Explore the universe of human proteins at neXtProt for CMC2: NX_Q9NRP2

Explore proteomics data for CMC2 at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See CMC2 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_064573.1  
    ENSEMBL proteins: 
     ENSP00000455880   ENSP00000457106   ENSP00000456177   ENSP00000219400   ENSP00000454709  
     ENSP00000456841   ENSP00000455457   ENSP00000454658   ENSP00000455177   ENSP00000455723  
     ENSP00000454396   ENSP00000454240   ENSP00000455404   ENSP00000454938   ENSP00000457938  

    CMC2 Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
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    OriGene Protein Over-expression Lysate for CMC2
    OriGene Custom MassSpec
    OriGene Custom Protein Services for CMC2
    GenScript Custom Purified and Recombinant Proteins Services for CMC2
    Novus Biologicals CMC2 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Browse Proteins at Cloud-Clone Corp.

     
    Search eBioscience for Proteins for CMC2 

    CMC2 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
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    Novus Biologicals CMC2 Antibodies
    Search for Antibodies for CMC2 at Abcam
    Browse Antibodies at Cloud-Clone Corp.
    ThermoFisher Antibody for CMC2
    LSBio Antibodies in human, mouse, rat for CMC2

    CMC2 Assay Products:

    Browse Kits and Assays available from EMD Millipore
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    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for CMC2
    Browse Enzo Life Sciences for kits & assays
    Browse ELISAs at Cloud-Clone Corp.
    Browse CLIAs at Cloud-Clone Corp.
    Search eBioscience for ELISAs for CMC2 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    1 InterPro protein domain:
     IPR013892 Cyt_c_biogenesis_Cmc1-like

    Graphical View of Domain Structure for InterPro Entry Q9NRP2

    ProtoNet protein and cluster: Q9NRP2

    1 Blocks protein domain: IPB013892 Protein of unknown function UPF0287

    UniProtKB/Swiss-Prot: COXM2_HUMAN, Q9NRP2
    Similarity: Belongs to the CMC family


    Find genes that share domains with CMC2           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: COXM2_HUMAN, Q9NRP2
    Function: May be involved in cytochrome c oxidase biogenesis (By similarity)

    Phenotypes:
         1 GenomeRNAi human phenotype for CMC2:

     Decreased viability of wild-ty 

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for CMC2
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for CMC2

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for CMC2
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for CMC2

    miRNA
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    miRTarBase miRNAs that target CMC2:
    hsa-mir-26b-5p (MIRT029078)

    Block miRNA regulation of human, mouse, rat CMC2 using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate CMC2
    SwitchGear 3'UTR luciferase reporter plasmidCMC2 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for CMC2
    Predesigned siRNA for gene silencing in human, mouse, rat CMC2

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for CMC2

    Clone
    Products:
         
    OriGene clones in human, mouse for CMC2 (see all 6)
    OriGene ORF clones in mouse, rat for CMC2
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript Custom all cDNA clones Services for CMC2
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CMC2
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CMC2

    Cell Line
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    Browse ESI BIO Cell Lines and PureStem Progenitors for CMC2 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CMC2


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    COXM2_HUMAN, Q9NRP2: Mitochondrion

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005739mitochondrion IDA--

    Find genes that share ontologies with CMC2           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for CMC2
    Interactions:

        Search GeneGlobe Interaction Network for CMC2

    STRING Interaction Network Preview (showing 3 interactants - click image to see more details)

    3 Interacting proteins for CMC2 (ENSP000002194004) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CMC1ENSP000004183484STRING: ENSP00000418348
    SLU7ENSP000002971514STRING: ENSP00000297151
    ZC3H14ENSP000002510384STRING: ENSP00000251038
    About this table

    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for CMC2 (COXM2)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for CMC2 gene: 
    NM_020188.3  

    Unigene Cluster for CMC2:

    COX assembly mitochondrial protein 2 homolog (S. cerevisiae)
    Hs.55028  [show with all ESTs]
    Unigene Representative Sequence: BM463756
    Selected Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 23):
    ENST00000566918 ENST00000563779 ENST00000566231 ENST00000561614 ENST00000566047
    ENST00000570195 ENST00000486645 ENST00000219400(uc002ffu.3) ENST00000569187
    ENST00000570086 ENST00000564249 ENST00000565650 ENST00000567593 ENST00000568228
    ENST00000565914 ENST00000565925 ENST00000565108 ENST00000564174
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat CMC2 using miScript Target Protectors
    Search for qRT-PCR Assays for microRNAs that regulate CMC2
    SwitchGear 3'UTR luciferase reporter plasmidCMC2 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for CMC2
    Predesigned siRNA for gene silencing in human, mouse, rat CMC2
    Clone
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    OriGene clones in human, mouse for CMC2 (see all 6)
    OriGene ORF clones in mouse, rat for CMC2
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript Custom all cDNA clones Services for CMC2
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CMC2
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CMC2
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for CMC2
    OriGene qSTAR qPCR primer pairs in human, mouse for CMC2
    Search Pre-validated RT2 qPCR Primer Assays in human, mouse, rat CMC2
      QuantiTect SYBR Green Assays in human, mouse, rat CMC2
      QuantiFast Probe-based Assays in human, mouse, rat CMC2

    Additional mRNA sequence: 

    AF201935.1 BC032631.1 

    19 DOTS entries:

    DT.455062  DT.120659234  DT.100029543  DT.99998496  DT.92428050  DT.100819614  DT.100819615  DT.100819612 
    DT.92428037  DT.100029544  DT.100819613  DT.97844709  DT.100029547  DT.100819611  DT.95311427  DT.100819610 
    DT.86997986  DT.95311439  DT.97844708 

    Selected AceView cDNA sequences (see all 219):

    BQ016378 AA838697 AK123193 AA757078 BM745049 CD367316 BM314268 AA902825 
    AA640163 CK299707 AA729656 BU627200 AA437055 CR594333 AA767427 CA946872 
    AW026947 BM704010 CB250688 BU681898 AI784635 AI187055 AI207323 BI793007 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for CMC2 (see all 8)    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3a · 3b · 3c ^ 4 ^ 5 ^ 6a · 6b · 6c · 6d · 6e · 6f
    SP1:              -     -     -                                                         
    SP2:                                                                                    
    SP3:              -     -     -                 -                                       
    SP4:                    -     -                 -                                       
    SP5:                                            -                                       


    ECgene alternative splicing isoforms for CMC2

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    CMC2 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    CMC2 Expression
    About this image

    CMC2 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    CMC2 Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.55028
        Custom PCR Arrays for CMC2
    Primer
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    OriGene qPCR primer pairs and template standards for CMC2
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    QuantiFast Probe-based Assays in human, mouse, rat CMC2
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CMC2

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of animals.

    Orthologs for CMC2 gene from Selected species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Cmc21 , 5 RIKEN cDNA 2310061C15 gene5
    COX assembly mitochondrial protein 21
    81.01(n)1
    82.28(a)1
      8 (63.28 cM)5
    665311  NM_026844.31  NP_081120.21 
     1168886855 
    chicken
    (Gallus gallus)
    Aves C16ORF611 chromosome 11 open reading frame, human C16orf61 71.11(n)
    65.33(a)
      770023  NM_001164348.1  NP_001157820.1 
    lizard
    (Anolis carolinensis)
    Reptilia CMC26
    C-x(9)-C motif containing 2
    73(a)
    1 ↔ 1
    LGc(5660948-5663403)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.109542 Xenopus laevis cDNA clone IMAGE4032905, partial cds 76.5(n)    BC060385.1 
    zebrafish
    (Danio rerio)
    Actinopterygii cmc21 COX assembly mitochondrial protein 2 homolog (S. cerevisiae) 59.21(n)
    61.84(a)
      368857  NM_001002614.1  NP_001002614.1 
    fruit fly
    (Drosophila melanogaster)
    Insecta CG423756
    --
    39(a)
    1 ↔ 1
    3R(9605346-9606517)
    worm
    (Caenorhabditis elegans)
    Secernentea C35D10.176
    Protein C35D10.17 (C35D10.17) mRNA, complete cds
    26(a)
    1 ↔ 1
    III(4867062-4867469) WBGene00016452


    ENSEMBL Gene Tree for CMC2 (if available)
    TreeFam Gene Tree for CMC2 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for CMC2 gene

    Find genes that share paralogs with CMC2           About GenesLikeMe


    Selected Pseudogenes.org Pseudogenes for CMC2 (see all 7)
    PGOHUM00000246701 PGOHUM00000246993 PGOHUM00000248827 PGOHUM00000249072 PGOHUM00000249085


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for CMC2 (see all 957)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 16 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs341577961,2
    C--66781516(+) TTTTT-/T/T   
       T
    /TTT
    AACAG
    2 -- int1 cds11NA 2
    rs1917842011,2
    --81009248(+) GCTCAC/TGCTTG 1 -- int10--------
    rs558526721,2
    C,F--81009347(+) CTCTAC/ACAAAA 1 -- int11Minor allele frequency- A:0.50WA 2
    rs285442511,2
    C,F--81009385(+) CTGCGC/TCTGTA 1 -- int18Minor allele frequency- T:0.18NA WA CSA EA 368
    rs1883533351,2
    --81009390(+) CCTGTA/TGCCCC 1 -- int10--------
    rs603786151,2
    C--81009403(+) CTACT-/AGAGAG 1 -- int10--------
    rs1138366081,2
    F--81009409(+) GAGAGG/CCTGAG 1 -- int11Minor allele frequency- C:0.50CSA 2
    rs99214481,2
    C,F,A--81009490(+) TGGGCA/GGCAAA 1 -- int110Minor allele frequency- G:0.42NA WA CSA EA 370
    rs348443321,2
    C--81009520(+) AAAAAT/-TTTTT 1 -- int11Minor allele frequency- -:0.00CSA 2
    rs798171731,2
    C--81009520(+) AAAAA-/TTTTTT 1 -- int10--------

    HapMap Linkage Disequilibrium report for CMC2 (81009698 - 81053875 bp)

    Structural Variations
          Database of Genomic Variants (DGV) variations for CMC2: --
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing CMC2
    DNA2.0 Custom Variant and Variant Library Synthesis for CMC2

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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      --

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for CMC2 gene, integrated from 10 sources (see all 12):
    (articles sorted by number of sources associating them with CMC2)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The conserved mitochondrial twin Cx9C protein Cmc2 Is a Cmc1 homologue essential for cytochrome c oxidase biogenesis. (PubMed id 20220131)1, 2, 3 Horn D....Barrientos A. (J. Biol. Chem. 2010)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    3. Pathway Analysis of ChIP-Seq-Based NRF1 Target Genes Suggests a Logical Hypothesis of their Involvement in the Pathogenesis of Neurodegenerative Diseases. (PubMed id 24250222)1 Satoh J....Yamamoto Y. (Gene Regul Syst Bio 2013)
    4. Proteomic dissection of the von Hippel-Lindau (VHL) interactome. (PubMed id 21942715)1 Lai Y....Shiio Y. (J. Proteome Res. 2011)
    5. Potential novel candidate polymorphisms identified in genome-wide association study for breast cancer susceptibility. (PubMed id 21424380)1 Sehrawat B....Damaraju S. (Hum. Genet. 2011)
    6. Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (BMC Syst. Biol. 2011)
    7. Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (amp 2011)
    8. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    9. Fine mapping and association studies of a high-density lipoprotein cholesterol linkage region on chromosome 16 in French-Canadian subjects. (PubMed id 19844255)1 Dastani Z....Genest J. (Eur. J. Hum. Genet. 2010)
    10. The sequence and analysis of duplication-rich human chromosome 16. (PubMed id 15616553)2 Martin J.... Pennacchio L.A. (Nature 2004)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 56942 HGNC: 24447 AceView: DC13 Ensembl:ENSG00000103121 euGenes: HUgn56942
    ECgene: CMC2 H-InvDB: CMC2

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for CMC2 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for CMC2 gene:
    Search GeneIP for patents involving CMC2

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

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