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CLUL1 Gene

protein-coding   GIFtS: 46
GCID: GC18P000597

Clusterin-Like 1 (Retinal)

  See CLUL1-related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Clusterin-Like 1 (Retinal)1 2
Retinal-Specific Clusterin-Like Protein2 3
RA337M2
Clusterin-Like Protein 12

External Ids:    HGNC: 20961   Entrez Gene: 270982   Ensembl: ENSG000000791017   UniProtKB: Q158463   

Export aliases for CLUL1 gene to outside databases

Previous GC identifers: GC18P000880 GC18P000584 GC18P000586


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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GeneCards Summary for CLUL1 Gene:
CLUL1 (clusterin-like 1 (retinal)) is a protein-coding gene. Diseases associated with CLUL1 include myopia-2. An important paralog of this gene is CLU.


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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Regulatory elements:
   Regulatory transcription factor binding sites in the CLUL1 gene promoter:
         SRF   Sp1   Bach2   SRF (504 AA)   Gfi-1   IRF-2   Pax-3   Ik-2   GATA-6   FOXO4   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCLUL1 promoter sequence
   Search Chromatin IP Primers for CLUL1

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat CLUL1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 18p11.32   Ensembl cytogenetic band:  18p11.32   HGNC cytogenetic band: 18p11.32

CLUL1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CLUL1 gene location

GeneLoc information about chromosome 18         GeneLoc Exon Structure

GeneLoc location for GC18P000597:  view genomic region     (about GC identifiers)

Start:
596,988 bp from pter      End:
650,334 bp from pter
Size:
53,347 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: CLUL1_HUMAN, Q15846 (See protein sequence)
Recommended Name: Clusterin-like protein 1 precursor  
Size: 466 amino acids; 54215 Da
Secondary accessions: A0FDN7

Explore the universe of human proteins at neXtProt for CLUL1: NX_Q15846

Explore proteomics data for CLUL1 at MOPED

Post-translational modifications: 

  • Glycosylation2 at Asn196, Asn257, Asn311, Asn351, Asn412, Asn431

  • See CLUL1 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (3 alternative transcripts): 
    NP_001275965.1  NP_055225.1  NP_954636.1  

    ENSEMBL proteins: 
     ENSP00000473520   ENSP00000383449   ENSP00000441726   ENSP00000463269   ENSP00000341128  
     ENSP00000464642   ENSP00000473543  

    CLUL1 Human Recombinant Protein Products:

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    OriGene Custom MassSpec
    OriGene Custom Protein Services for CLUL1
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    Novus Biologicals CLUL1 Protein
    Novus Biologicals CLUL1 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for CLUL1

     
    Search eBioscience for Proteins for CLUL1 

    CLUL1 Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    R&D Systems Antibodies for CLUL1 (Clusterin-like 1/CLUL1)
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    Novus Biologicals CLUL1 Antibodies
    Abcam antibodies for CLUL1
    Cloud-Clone Corp. Antibodies for CLUL1
    ThermoFisher Antibodies for CLUL1
    LSBio Antibodies in human, mouse, rat for CLUL1

    CLUL1 Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for CLUL1
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for CLUL1
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for CLUL1
    Cloud-Clone Corp. CLIAs for CLUL1
    Search eBioscience for ELISAs for CLUL1 


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    3 InterPro protein domains:
     IPR000753 Clusterin-like
     IPR016014 Clusterin_N
     IPR016015 Clusterin_C

    Graphical View of Domain Structure for InterPro Entry Q15846

    ProtoNet protein and cluster: Q15846

    UniProtKB/Swiss-Prot: CLUL1_HUMAN, Q15846
    Similarity: Belongs to the clusterin family


    Find genes that share domains with CLUL1           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for CLUL1
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for CLUL1

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for CLUL1
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for CLUL1

    miRNA
    Products:
        
    Block miRNA regulation of human, mouse, rat CLUL1 using miScript Target Protectors
    1 qRT-PCR Assays for microRNA that regulate CLUL1:
    hsa-miR-3674
    SwitchGear 3'UTR luciferase reporter plasmidCLUL1 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for CLUL1
    Predesigned siRNA for gene silencing in human, mouse, rat CLUL1

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for CLUL1

    Clone
    Products:
         
    OriGene clones in human, mouse for CLUL1 (see all 10)
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): CLUL1 (NM_199167)
    Sino Biological Human cDNA Clone for CLUL1
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CLUL1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CLUL1

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for CLUL1
    Browse ESI BIO Cell Lines and PureStem Progenitors for CLUL1 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CLUL1


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    CLUL1_HUMAN, Q15846: Secreted (Probable)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    extracellular4
    endoplasmic reticulum1

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005576extracellular region IEA--

    Find genes that share ontologies with CLUL1           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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        Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for CLUL1
    Interactions:

        Search GeneGlobe Interaction Network for CLUL1

    STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

    2 Interacting proteins for CLUL1 (ENSP000003411284) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CLUAP1ENSP000003443924STRING: ENSP00000344392
    XRCC6ENSP000003522574STRING: ENSP00000352257
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0008219cell death IEA--

    Find genes that share ontologies with CLUL1           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for CLUL1



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for CLUL1 gene (3 alternative transcripts): 
    NM_001289036.1  NM_014410.4  NM_199167.1  

    12 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000579912 ENST00000582020 ENST00000580436 ENST00000400606(uc002kkp.3)
    ENST00000579443 ENST00000540035(uc010wys.2) ENST00000581619 ENST00000584370
    ENST00000338387(uc002kkq.3) ENST00000579494 ENST00000584046 ENST00000585155

    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat CLUL1 using miScript Target Protectors
    1 qRT-PCR Assays for microRNA that regulate CLUL1:
    hsa-miR-3674
    SwitchGear 3'UTR luciferase reporter plasmidCLUL1 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for CLUL1
    Predesigned siRNA for gene silencing in human, mouse, rat CLUL1
    Clone
    Products:
         
    OriGene clones in human, mouse for CLUL1 (see all 10)
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector (see all 2): CLUL1 (NM_199167)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CLUL1
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CLUL1
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for CLUL1
    OriGene qSTAR qPCR primer pairs in human, mouse for CLUL1
    Pre-validated RT2 qPCR Primer Assay in human, mouse / rat CLUL1
      QuantiTect SYBR Green Assays in human, mouse, rat CLUL1
      QuantiFast Probe-based Assays in human, mouse, rat CLUL1

    Selected AceView cDNA sequences (see all 35):

    BM701786 NM_014410 AA781524 BQ637390 BQ017160 BC025381 NM_199167 BM692454 
    CD105363 AL712219 AF395889 AA317281 AL712819 BU728997 H91726 BX488483 
    H91647 BI489991 D63813 BG704533 BV177012 AK094657 BX488227 AI654367 

    GeneLoc Exon Structure

    Selected Alternative Splicing Database (ASD) splice patterns (SP) for CLUL1 (see all 6)    About this scheme

    ExUns: 1a · 1b ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7a · 7b ^ 8 ^ 9a · 9b ^ 10 ^ 11 ^ 12 ^ 13
    SP1:              -           -     -                                                               
    SP2:                                                                                                
    SP3:              -     -     -     -                                                               
    SP4:                                                                                                
    SP5:                          -     -                                                               


    ECgene alternative splicing isoforms for CLUL1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    CLUL1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GTACATTAGT
    CLUL1 Expression
    About this image

    CLUL1 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    CLUL1 Protein Expression
        Custom PCR Arrays for CLUL1
    Primer
    Products:
    OriGene qPCR primer pairs and template standards for CLUL1
    OriGene qSTAR qPCR primer pairs in human, mouse for CLUL1
    Pre-validated RT2 qPCR Primer Assay in human, mouse / rat CLUL1
    QuantiTect SYBR Green Assays in human, mouse, rat CLUL1
    QuantiFast Probe-based Assays in human, mouse, rat CLUL1
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CLUL1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of chordates.

    Orthologs for CLUL1 gene from Selected species (see all 10)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    rat
    (Rattus norvegicus)
    Mammalia Clul11 clusterin-like 1 (retinal) 75.79(n)
    60.56(a)
      367345  NM_001033071.1  NP_001028243.1 
    chicken
    (Gallus gallus)
    Aves CLUL11 clusterin-like 1 (retinal) 64.52(n)
    52.99(a)
      768430  XM_001231314.2  XP_001231315.2 
    lizard
    (Anolis carolinensis)
    Reptilia CLUL16
    clusterin-like 1 (retinal)
    49(a)
    1 ↔ 1
    4(39494128-39511606)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia clul11 clusterin-like 1 (retinal) 50.91(n)
    33.64(a)
      100495904  XM_002934133.2  XP_002934179.2 
    zebrafish
    (Danio rerio)
    Actinopterygii clul11 clusterin-like 1 (retinal) 46.8(n)
    33.48(a)
      559018  NM_001099994.2  NP_001093464.1 


    ENSEMBL Gene Tree for CLUL1 (if available)
    TreeFam Gene Tree for CLUL1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for CLUL1 gene
    CLU2  
    Selected SIMAP similar genes for CLUL1 using alignment to 5 protein entries:     CLUL1_HUMAN (see all proteins) (see all similar genes):
    ZNF212    CERS5    NF2    ZNF28    CTSS    APOD
    CHID1    RNF217    TMEM14B    ZNF737    ZNF83    LYRM4
    TCF4    ZNF20    UTY    CLU    TSEN2    LINC00596

    Find genes that share paralogs with CLUL1           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for CLUL1 (see all 1319)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 18 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1466064061,2
    --595044(+) GGTAAA/GGGAAA 1 -- us2k10--------
    rs1390028841,2
    C--595111(+) ACCCCA/GACTCT 1 -- us2k10--------
    rs1127557241,2
    C,F--595124(+) AGTTTG/AATCAA 1 -- us2k12Minor allele frequency- A:0.12CSA WA 120
    rs739425701,2
    C--595136(+) TTGTCA/CAATTA 1 -- us2k13Minor allele frequency- C:0.07WA EA 240
    rs739425711,2
    C--595275(+) GGCAAC/TCAAAA 1 -- us2k13Minor allele frequency- T:0.08WA EA 240
    rs1157958281,2
    F--595304(+) CTGAAC/TATTCT 1 -- us2k11Minor allele frequency- T:0.03WA 118
    rs126048401,2
    C,F,H--595359(+) aattaG/Acctga 1 -- us2k15Minor allele frequency- A:0.01NS EA NA 390
    rs774765001,2
    C--595382(+) TCAAAC/TCTGAT 1 -- us2k10--------
    rs1818061811,2
    --595423(+) TCGTTC/TGTGAT 1 -- us2k10--------
    rs1118694211,2
    C,F--595486(+) GTAAAG/CTGGCT 1 -- us2k11Minor allele frequency- C:0.50CSA 2

    HapMap Linkage Disequilibrium report for CLUL1 (596988 - 650334 bp)

    Structural Variations
         Database of Genomic Variants (DGV) Selected variations for CLUL1 (see all 17):    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2716649CNV Deletion23290073
    esv2716645CNV Deletion23290073
    esv2716650CNV Deletion23290073
    esv2716646CNV Deletion23290073
    esv2663170CNV Deletion23128226
    esv2716648CNV Deletion23290073
    dgv574e199CNV Deletion23128226
    esv2676596CNV Deletion23128226
    esv1619817CNV Deletion17803354
    nsv131524CNV Loss16902084

    Human Gene Mutation Database (HGMD): CLUL1
    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing CLUL1
    DNA2.0 Custom Variant and Variant Library Synthesis for CLUL1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    1 disease for CLUL1:    
    About MalaCards
    myopia-2


    Find genes that share disorders with CLUL1           About GenesLikeMe

    1 Novoseek inferred disease relationship for CLUL1 gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    retinopathy 51 2 14507903 (1), 10675623 (1)

    Genetic Association Database (GAD): CLUL1
    Human Genome Epidemiology (HuGE) Navigator: CLUL1 (4 documents)

    Export disorders for CLUL1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for CLUL1 gene, integrated from 10 sources (see all 11):
    (articles sorted by number of sources associating them with CLUL1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Comparative analysis and expression of CLUL1, a cone photoreceptor- specific gene. (PubMed id 14507903)1, 2, 3, 9 Zhang Q....Aguirre G.D. (Invest. Ophthalmol. Vis. Sci. 2003)
    2. Molecular cloning, characterization and expression of a novel retinal clusterin-like protein cDNA. (PubMed id 10675623)1, 3, 9 Zhang Q....Aguirre G.D. (Gene 2000)
    3. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1, 4 Rose J.E....Uhl G.R. (Mol. Med. 2010)
    4. Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)1, 4 Bailey S.D....Anand S. (Diabetes Care 2010)
    5. Mapping of transcription start sites of human retina expressed genes. (PubMed id 17286855)1, 2 Roni V.... Wissinger B. (BMC Genomics 2007)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    7. Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip. (PubMed id 19913121)1 Talmud P.J.... . (Am. J. Hum. Genet. 2009)
    8. A genome-wide association study for blood lipid phenotypes in the Framingham Heart Study. (PubMed id 17903299)4 Kathiresan S....Cupples L.A. (BMC Med. Genet. 2007)
    9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    10. Mutation screen of the cone-specific gene, CLUL1, in 376 patients with age-related macular degeneration. (PubMed id 17148042)9 Sturgill G.M....Hagstrom S.A. (Ophthalmic Genet. 2006)

    (in PubMed, OMIM, and NCBI Bookshelf)
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     ANDOR
    Aliases
    Disorders
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 27098 HGNC: 2096 AceView: CLUL1 Ensembl:ENSG00000079101 euGenes: HUgn27098
    ECgene: CLUL1 H-InvDB: CLUL1

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for CLUL1 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

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    Patent Information for CLUL1 gene:
    Search GeneIP for patents involving CLUL1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, eBioscience, and/or others, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Addgene, Cell lines from GenScript, and ESI BIO, Flow cytometery from eBioscience, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

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     Search Addgene for plasmids for CLUL1
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