Aliases for CLTB Gene
External Ids for CLTB Gene
Previous GeneCards Identifiers for CLTB Gene
Clathrin is a large, soluble protein composed of heavy and light chains. It functions as the main structural component of the lattice-type cytoplasmic face of coated pits and vesicles which entrap specific macromolecules during receptor-mediated endocytosis. This gene encodes one of two clathrin light chain proteins which are believed to function as regulatory elements. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008]
GeneCards Summary for CLTB Gene
CLTB (Clathrin Light Chain B) is a Protein Coding gene. Diseases associated with CLTB include Leber Congenital Amaurosis 6 and Leber Congenital Amaurosis. Among its related pathways are Gap junction trafficking and wtCFTR and delta508-CFTR traffic / Generic schema (norm and CF). GO annotations related to this gene include structural molecule activity and peptide binding. An important paralog of this gene is CLTA.
UniProtKB/Swiss-Prot for CLTB Gene
Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.