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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

CLSTN3 Gene

protein-coding   GIFtS: 55
GCID: GC12P007282

Calsyntenin 3

  See related disease
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Calsyntenin 31 2     alcbeta2
Cadherin-Related Family Member 141 2     calsyntenin-32
CDHR142     Alc-beta3
CSTN32     Alcadein-beta3
alc-beta2     CS33
Alcadein Beta2     KIAA07263
alcadein-beta2     

External Ids:    HGNC: 183711   Entrez Gene: 97462   Ensembl: ENSG000001391827   OMIM: 6113245   UniProtKB: Q9BQT93   

Export aliases for CLSTN3 gene to outside databases

Previous GC identifers: GC12P007242 GC12P007418 GC12P007174 GC12P007095


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

GeneCards Summary for CLSTN3 Gene: 
CLSTN3 (calsyntenin 3) is a protein-coding gene. Diseases associated with CLSTN3 include neuronitis. GO annotations related to this gene include calcium ion binding. An important paralog of this gene is CLSTN1.

UniProtKB/Swiss-Prot: CSTN3_HUMAN, Q9BQT9
Function: May modulate calcium-mediated postsynaptic signals (By similarity). Complex formation with APBA2 and
APP, stabilizes APP metabolism and enhances APBA2-mediated suppression of beta-APP40 secretion, due to the
retardation of intracellular APP maturation (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000012.11  NT_009714.17  NC_018923.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the CLSTN3 gene promoter:
         MZF-1   PPAR-gamma1   ISGF-3   AML1a   RREB-1   ARP-1   HNF-4alpha2   PPAR-gamma2   HNF-4alpha1   RORalpha2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCLSTN3 promoter sequence
   Search SABiosciences Chromatin IP Primers for CLSTN3

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CLSTN3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12p13.31   Ensembl cytogenetic band:  12p13.31   HGNC cytogenetic band: 12p13.31

CLSTN3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CLSTN3 gene location

GeneLoc information about chromosome 12         GeneLoc Exon Structure

GeneLoc location for GC12P007282:  view genomic region     (about GC identifiers)

Start:
7,282,294 bp from pter      End:
7,311,541 bp from pter
Size:
29,248 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: CSTN3_HUMAN, Q9BQT9 (See protein sequence)
Recommended Name: Calsyntenin-3 precursor  
Size: 956 amino acids; 106098 Da
Subunit: Directly interacts with APBA2. Forms a tripartite complex with APBA2 and APP. Interacts with low affinity
with KLC1 (By similarity)
Subcellular location: Cell membrane; Single-pass type I membrane protein (Potential). Endoplasmic reticulum
membrane. Golgi apparatus membrane. Note=Most prominent in the postsynaptic specializations of asymmetric (type
I) synapses with both axodendritic and axospinous localization (By similarity)
Sequence caution: Sequence=BAA34446.2; Type=Erroneous initiation; Note=Translation N-terminally shortened;
Secondary accessions: D3DUT6 O94831 Q2T9J5 Q5UE57
Alternative splicing: 2 isoforms:  Q9BQT9-1   Q9BQT9-2   

Explore the universe of human proteins at neXtProt for CLSTN3: NX_Q9BQT9

Explore proteomics data for CLSTN3 at MOPED 

Post-translational modifications:

  • UniProtKB: Proteolytically processed under normal cellular conditions. A primary zeta-cleavage generates a large
    extracellular (soluble) N-terminal domain (sAlc) and a short C-terminal transmembrane fragment (CTF1). A
    secondary cleavage catalyzed by gamma-secretase within the transmembrane domain releases the beta-Alc-beta chain
    in the extracellular milieu and produces an intracellular fragment (AlcICD). This processing is strongly
    suppressed in the tripartite complex formed with APBA2 and APP, which seems to prevent the association with
    gamma-secretase (By similarity)
  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9BQT9

  • CLSTN3 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    CLSTN3 Protein Expression
    REFSEQ proteins: NP_055533.2  
    ENSEMBL proteins: 
     ENSP00000443959   ENSP00000266546   ENSP00000442612   ENSP00000443468   ENSP00000443490  
     ENSP00000442801   ENSP00000440679  

    Human Recombinant Protein Products for CLSTN3: 
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    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for CLSTN3 

    Gene Ontology (GO): 5/6 cellular component terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0000139Golgi membrane IEA--
    GO:0005789endoplasmic reticulum membrane IEA--
    GO:0005886plasma membrane IEA--
    GO:0016020membrane ----
    GO:0016021integral to membrane IEA--

    CLSTN3 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    CDHR: Cadherins / Cadherin-related

    5 InterPro protein domains:
     IPR026914 Calsyntenin
     IPR013320 ConA-like_subgrp
     IPR015919 Cadherin-like
     IPR002126 Cadherin
     IPR008985 ConA-like_lec_gl_sf

    Graphical View of Domain Structure for InterPro Entry Q9BQT9

    ProtoNet protein and cluster: Q9BQT9

    1 Blocks protein domain: IPB002126 Cadherin

    UniProtKB/Swiss-Prot: CSTN3_HUMAN, Q9BQT9
    Domain: Binds synaptic Ca(2+) with its cytoplasmic domain (By similarity)
    Similarity: Contains 2 cadherin domains


    CLSTN3 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: CSTN3_HUMAN, Q9BQT9
    Function: May modulate calcium-mediated postsynaptic signals (By similarity). Complex formation with APBA2 and
    APP, stabilizes APP metabolism and enhances APBA2-mediated suppression of beta-APP40 secretion, due to the
    retardation of intracellular APP maturation (By similarity)

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005509calcium ion binding IEA--
         
    CLSTN3 for ontologies           About GeneDecksing


    Phenotypes:
         3 GenomeRNAi human phenotypes for CLSTN3:
     Decreased influenza A H1N1 (A/  Decreased influenza A/WSN/33 r  Synthetic lethal with Ras 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for CLSTN3 
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    SwitchGear 3'UTR luciferase reporter plasmidCLSTN3 3' UTR sequence
    Inhib. RNA
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CLSTN3

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    3 Interacting proteins for CLSTN3 (Q9BQT93 ENSP000002665464) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    APBA2Q997673I2D: score=1 
    APPP050673I2D: score=1 
    --ENSP000002198654STRING: ENSP00000219865
    About this table

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0007156homophilic cell adhesion IEA--

    CLSTN3 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for CLSTN3 (CSTN3)

    1 HMDB Compound for CLSTN3    About this table
    CompoundSynonyms CAS #PubMed Ids
    CalciumCa (see all 2)7440-70-2--

    Search CenterWatch for drugs/clinical trials and news about CLSTN3 / CSTN3

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for CLSTN3 gene: 
    NM_014718.3  

    Unigene Cluster for CLSTN3:

    Calsyntenin 3
    Hs.535378  [show with all ESTs]
    Unigene Representative Sequence: BC111491
    16 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000541953 ENST00000266546(uc001qsr.3) ENST00000541667 ENST00000545663
    ENST00000535452 ENST00000534830 ENST00000539982 ENST00000537408(uc001qss.3)
    ENST00000538933 ENST00000540931 ENST00000535668 ENST00000544584 ENST00000541770
    ENST00000542663 ENST00000331148(uc001qst.3) ENST00000535313
    miRNA
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    6 QIAGEN miScript miRNA Assays for microRNAs that regulate CLSTN3:
    hsa-miR-323-3p hsa-miR-203 hsa-miR-2355-5p hsa-miR-558 hsa-miR-570 hsa-miR-3160-3p
    SwitchGear 3'UTR luciferase reporter plasmidCLSTN3 3' UTR sequence
    Inhib. RNA
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    Additional mRNA sequence: 

    AJ277460.1 AK299177.1 AK299246.1 AK316059.1 AY753302.1 BC039075.1 BC104767.1 BC111491.1 
    BC112283.1 BC148258.1 

    21 DOTS entries:

    DT.92428328  DT.210859  DT.121182122  DT.100744691  DT.75108920  DT.121182118  DT.91825939  DT.97843682 
    DT.100647085  DT.100831074  DT.121182151  DT.121182162  DT.70102260  DT.75111753  DT.91746497  DT.92428326 
    DT.95075153  DT.97807651  DT.40112905  DT.91680679  DT.95075143 

    24/161 AceView cDNA sequences (see all 161):

    BQ416712 BX452281 AA322750 T30908 AJ277460 BG742627 BQ717902 BM683655 
    CA397727 BM702421 T33896 BI756741 BX954468 AA339760 BM711571 AL522578 
    NM_014718 Z42954 M78932 AA324658 BX112612 AA318791 CR621580 BM710970 

    GeneLoc Exon Structure

    5/14 Alternative Splicing Database (ASD) splice patterns (SP) for CLSTN3 (see all 14)    About this scheme

    ExUns: 1a · 1b · 1c · 1d ^ 2 ^ 3 ^ 4 ^ 5 ^ 6a · 6b · 6c ^ 7 ^ 8a · 8b ^ 9a · 9b · 9c · 9d ^ 10 ^ 11 ^ 12a · 12b ^ 13 ^ 14 ^ 15 ^ 16 ^
    SP1:                          -     -     -     -     -     -                       -                                               -           -               
    SP2:                                                                                -                                               -           -               
    SP3:                                                                                                                                                            
    SP4:              -     -     -     -     -     -     -     -     -     -           -                                                                           
    SP5:                                -     -     -     -     -                       -                                                                           

    ExUns: 17 ^ 18a · 18b ^ 19 ^ 20 ^ 21 ^ 22a · 22b ^ 23a · 23b ^ 24a · 24b ^ 25a · 25b · 25c · 25d
    SP1:                                            -     -     -           -                           
    SP2:                                            -     -     -           -                           
    SP3:                                                                                                
    SP4:                                                                                                
    SP5:                                                                                                


    ECgene alternative splicing isoforms for CLSTN3

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    CLSTN3 expression in normal human tissues (normalized intensities)      CLSTN3 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TCCTGGGGCA
    CLSTN3 Expression
    About this image


    CLSTN3 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/2 selected tissues (see all 2) fully expand
     
     Adipose (Muscoskeletal System)
             Interscapular Brown Adipose Depot
     
     Brain (Nervous System)
             cerebellum   

    See CLSTN3 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for CLSTN3

    SOURCE GeneReport for Unigene cluster: Hs.535378

    UniProtKB/Swiss-Prot: CSTN3_HUMAN, Q9BQT9
    Tissue specificity: According to PubMed:12498782, expressed predominantly in the brain and in kidney. Low levels
    in heart, skeletal muscle, liver, placenta, pancreas and lung. According to PubMed:12972431, predominant
    expression in brain, and only marginal in kidney. In brain, present throughout all cortical layers, highest
    levels in GABAergic neurons (based on morphology and distribution pattern)

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    In Situ
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CLSTN3

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals.

    Orthologs for CLSTN3 gene from 7/14 species (see all 14)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Clstn31 , 5 calsyntenin 31, 5 89.82(n)1
    95.71(a)1
      6 (59.15 cM)5
    2323701  NM_153508.41  NP_705728.11 
     1244307595 
    chicken
    (Gallus gallus)
    Aves CLSTN31 calsyntenin 3 77.14(n)
    83.54(a)
      418297  XM_416520.3  XP_416520.3 
    lizard
    (Anolis carolinensis)
    Reptilia CLSTN36
    Uncharacterized protein
    71(a)
    1 ↔ 1
    GL343218.1(166906-200181)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia Str.132952 Transcribed sequence with moderate similarity to protein more 75.13(n)    BX726645.1 
    zebrafish
    (Danio rerio)
    Actinopterygii LOC5556271 calsyntenin-3-like 65.3(n)
    63.78(a)
      555627  XM_678194.5  XP_683286.4 
    fruit fly
    (Drosophila melanogaster)
    Insecta calsyntenin-13 calcium-dependent cell-cell adhesion
    calcium-dependent more
    27(a)   102D4   --
    worm
    (Caenorhabditis elegans)
    Secernentea casy-16
    Protein CASY-1, isoform a
    23(a)
    1 → many
    II(5945406-5956685)


    ENSEMBL Gene Tree for CLSTN3 (if available)
    TreeFam Gene Tree for CLSTN3 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for CLSTN3 gene
    CLSTN12  CLSTN22  
    2 SIMAP similar genes for CLSTN3 using alignment to 7 protein entries:     CSTN3_HUMAN (see all proteins):
    CLSTN1    CLSTN2

    CLSTN3 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/743 SNPs in CLSTN3 are shown (see all 743)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 12 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0361144
    A colorectal cancer sample4--see VAR_0361142 H Y mis40--------
    rs762225411,2
    C,F--7283522(+) CCCATG/TCGTTT 1 -- int11Minor allele frequency- T:0.03WA 118
    rs37594161,2
    C,F--7283646(-) CGGCTC/TGGGGG 1 -- int15Minor allele frequency- T:0.20CSA WA NA EA 362
    rs1155962171,2
    C,F--7283906(+) GACAGA/GCGGAG 1 -- int11Minor allele frequency- G:0.03NA 120
    rs18687981,2
    C,F,A,H--7284081(+) GAGGGG/AATGGA 1 -- int1 trp324Minor allele frequency- A:0.29EA NS NA CSA WA 4158
    rs21672851,2
    C,F,A,H--7284301(+) TTCCAT/CCGCTC 1 -- int121Minor allele frequency- C:0.34EA NS WA NA CSA 3842
    rs1132977061,2
    C--7284340(+) GCCTCGCCTC   
       CTA
    /-
    GCCTC
    1 -- int11Minor allele frequency- -:0.50CSA 2
    rs40137211,2
    C--7284347(+) CTCCT-/AGC   
       CTCCT
    GCCAC
    1 -- int10--------
    rs107724661,2
    C,H--7284484(+) GAGGAC/AAGAAT 1 -- int1 trp312Minor allele frequency- A:0.09NA WA CSA 258
    rs1812874781,2
    --7284584(+) GGGAGC/TCTGGG 1 -- int10--------

    HapMap Linkage Disequilibrium report for CLSTN3 (7282294 - 7311541 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for CLSTN3:    About this table     
    Variant IDTypeSubtypePubMed ID
    nsv818882CNV Gain17921354
    nsv832325CNV Gain+Loss17160897

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing CLSTN3
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 611324    OMIM disorders: --

    2 diseases for CLSTN3:    About MalaCards
    neuronitis    


    CLSTN3 for disorders           About GeneDecksing


    Export disorders for CLSTN3 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for CLSTN3 gene integrated from 9 sources:
    (articles sorted by number of sources associating them with CLSTN3)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The calsyntenins - a family of postsynaptic membrane proteins with distinct neuronal expression patterns. (PubMed id 12498782)1, 2, 3 Hintsch G.... Sonderegger P. (2002)
    2. Coordinated metabolism of Alcadein and amyloid beta-protein precursor regulates FE65-dependent gene transactivation. (PubMed id 15037614)1, 2 Araki Y.... Suzuki T. (2004)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. Novel cadherin-related membrane proteins, Alcadeins, enhance the X11- like protein-mediated stabilization of amyloid beta-protein precursor metabolism. (PubMed id 12972431)1, 2 Araki Y....Suzuki T. (2003)
    5. Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro. (PubMed id 9872452)1, 2 Nagase T.... Ohara O. (1998)
    6. The consensus coding sequences of human breast and colorectal cancers. (PubMed id 16959974)2 Sjoeblom T.... Velculescu V.E. (2006)
    7. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)1 Kimura K.... Sugano S. (2006)
    8. The finished DNA sequence of human chromosome 12. (PubMed id 16541075)2 Scherer S.E.... Gibbs R.A. (2006)
    9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
    10. [The family of calsyntenins: learning and memory related genes] (PubMed id 17009726)9 Cheng X.R....Zhang Y.X. (2006)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 9746 HGNC: 18371 AceView: CLSTN3 Ensembl:ENSG00000139182 euGenes: HUgn9746
    ECgene: CLSTN3 H-InvDB: CLSTN3

    (According to HUGE)
    About This Section
    HUGE: KIAA0726

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for CLSTN3 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for CLSTN3 gene:
    Search GeneIP for patents involving CLSTN3

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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