Free for academic non-profit institutions. Other users need a Commercial license

Aliases for CLPSL2 Gene

Aliases for CLPSL2 Gene

  • Colipase Like 2 2 3 5
  • Colipase-Like 2 2 3
  • C6orf126 3 4
  • Chromosome 6 Open Reading Frame 126 2
  • Colipase-Like Protein C6orf126 3
  • DJ510O8.5 3
  • AAAL3045 3
  • UNQ3045 3

External Ids for CLPSL2 Gene

Previous HGNC Symbols for CLPSL2 Gene

  • C6orf126

Previous GeneCards Identifiers for CLPSL2 Gene

  • GC06P035745
  • GC06P035859
  • GC06P036313
  • GC06P037300
  • GC06P036831
  • GC06P036912

Summaries for CLPSL2 Gene

GeneCards Summary for CLPSL2 Gene

CLPSL2 (Colipase Like 2) is a Protein Coding gene. Diseases associated with CLPSL2 include Mitochondrial Complex Iii Deficiency, Nuclear Type 7. GO annotations related to this gene include enzyme activator activity.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CLPSL2 Gene

Genomics for CLPSL2 Gene

Regulatory Elements for CLPSL2 Gene

Enhancers for CLPSL2 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around CLPSL2 on UCSC Golden Path with GeneCards custom track

Promoters for CLPSL2 Gene
Ensembl Regulatory Elements (ENSRs) TSS Distance (bp) Size (bp) Binding Sites for Transcription Factors within promoters

ENSRs around CLPSL2 on UCSC Golden Path with GeneCards custom track

Genomic Location for CLPSL2 Gene

35,776,594 bp from pter
35,779,552 bp from pter
2,959 bases
Plus strand

Genomic View for CLPSL2 Gene

Genes around CLPSL2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CLPSL2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CLPSL2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CLPSL2 Gene

Proteins for CLPSL2 Gene

  • Protein details for CLPSL2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Colipase-like protein 2
    Protein Accession:
    Secondary Accessions:
    • B0QZ45
    • Q5T9G3

    Protein attributes for CLPSL2 Gene

    100 amino acids
    Molecular mass:
    10812 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for CLPSL2 Gene


neXtProt entry for CLPSL2 Gene

Proteomics data for CLPSL2 Gene at MOPED

Post-translational modifications for CLPSL2 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for CLPSL2 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for CLPSL2 Gene

Domains & Families for CLPSL2 Gene

Protein Domains for CLPSL2 Gene


Suggested Antigen Peptide Sequences for CLPSL2 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the colipase family.
  • Belongs to the colipase family.
genes like me logo Genes that share domains with CLPSL2: view

No data available for Gene Families for CLPSL2 Gene

Function for CLPSL2 Gene

Phenotypes for CLPSL2 Gene

genes like me logo Genes that share phenotypes with CLPSL2: view

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for CLPSL2 Gene

Localization for CLPSL2 Gene

Subcellular locations from UniProtKB/Swiss-Prot for CLPSL2 Gene


Subcellular locations from

Jensen Localization Image for CLPSL2 Gene COMPARTMENTS Subcellular localization image for CLPSL2 gene
Compartment Confidence
extracellular 5

No data available for Gene Ontology (GO) - Cellular Components for CLPSL2 Gene

Pathways & Interactions for CLPSL2 Gene

SuperPathways for CLPSL2 Gene

No Data Available

Interacting Proteins for CLPSL2 Gene

Gene Ontology (GO) - Biological Process for CLPSL2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007586 digestion IEA --
genes like me logo Genes that share ontologies with CLPSL2: view

No data available for Pathways by source and SIGNOR curated interactions for CLPSL2 Gene

Drugs & Compounds for CLPSL2 Gene

No Compound Related Data Available

Transcripts for CLPSL2 Gene

mRNA/cDNA for CLPSL2 Gene

(2) REFSEQ mRNAs :
(1) Additional mRNA sequences :
(5) Selected AceView cDNA sequences:
(4) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for CLPSL2 Gene

Colipase-like 2:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for CLPSL2 Gene

ExUns: 1a · 1b · 1c ^ 2 ^ 3 ^ 4
SP1: -
SP2: -

Relevant External Links for CLPSL2 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for CLPSL2 Gene

mRNA expression in normal human tissues for CLPSL2 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for CLPSL2 Gene

This gene is overexpressed in Pancreas (x28.6) and Brain - Anterior cingulate cortex (BA24) (x4.2).

SOURCE GeneReport for Unigene cluster for CLPSL2 Gene Hs.259563

genes like me logo Genes that share expression patterns with CLPSL2: view

Primer Products

No data available for Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Protein tissue co-expression partners for CLPSL2 Gene

Orthologs for CLPSL2 Gene

This gene was present in the common ancestor of mammals.

Orthologs for CLPSL2 Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia CLPSL2 35
  • 74.23 (n)
  • 67.01 (a)
(Canis familiaris)
Mammalia CLPSL2 35
  • 74.46 (n)
  • 66.23 (a)
  • 61 (a)
(Mus musculus)
Mammalia Clpsl2 35
  • 70.27 (n)
  • 62.16 (a)
Clpsl2 16
Clpsl2 36
  • 51 (a)
(Pan troglodytes)
Mammalia CLPSL2 35
  • 99.67 (n)
  • 100 (a)
  • 50 (a)
(Rattus norvegicus)
Mammalia Clpsl2 35
  • 65.02 (n)
  • 55.56 (a)
Species with no ortholog for CLPSL2:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for CLPSL2 Gene

Gene Tree for CLPSL2 (if available)
Gene Tree for CLPSL2 (if available)

Paralogs for CLPSL2 Gene

No data available for Paralogs for CLPSL2 Gene

Variants for CLPSL2 Gene

Sequence variations from dbSNP and Humsavar for CLPSL2 Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type
rs11754769 -- 35,776,321(+) tctgt(A/G)aaata upstream-variant-2KB
rs12176047 -- 35,775,167(+) TGGAA(A/G)AAGGG upstream-variant-2KB
rs12176049 -- 35,775,190(+) AATCA(A/G)ACTGT upstream-variant-2KB
rs12176067 -- 35,775,413(+) AAGCA(A/G)AAGCA upstream-variant-2KB
rs12193764 -- 35,774,779(+) cctcc(C/G)gagta upstream-variant-2KB

Variation tolerance for CLPSL2 Gene

Gene Damage Index Score: 5.92; 74.44% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Relevant External Links for CLPSL2 Gene

Disorders for CLPSL2 Gene

MalaCards: The human disease database

(1) MalaCards diseases for CLPSL2 Gene - From: OMIM

Disorder Aliases PubMed IDs
mitochondrial complex iii deficiency, nuclear type 7
  • mitochondrial complex iii deficiency nuclear type 7
- elite association - COSMIC cancer census association via MalaCards

Relevant External Links for CLPSL2

Atlas of Genetics and Cytogenetics in Oncology and Haematology:
genes like me logo Genes that share disorders with CLPSL2: view

No data available for UniProtKB/Swiss-Prot and Genatlas for CLPSL2 Gene

Publications for CLPSL2 Gene

  1. Signal peptide prediction based on analysis of experimentally verified cleavage sites. (PMID: 15340161) Zhang Z. … Henzel W.J. (Protein Sci. 2004) 3 4 67
  2. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PMID: 12975309) Clark H.F. … Gray A.M. (Genome Res. 2003) 3

Products for CLPSL2 Gene

Sources for CLPSL2 Gene