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Aliases for CLPSL1 Gene

Aliases for CLPSL1 Gene

  • Colipase Like 1 2 3 5
  • Colipase-Like 1 2 3
  • C6orf127 3 4
  • Chromosome 6 Open Reading Frame 127 2
  • Colipase-Like Protein C6orf127 3
  • DJ510O8.6 3
  • ESP32 3

External Ids for CLPSL1 Gene

Previous HGNC Symbols for CLPSL1 Gene

  • C6orf127

Previous GeneCards Identifiers for CLPSL1 Gene

  • GC06P035749
  • GC06P035862
  • GC06P036314
  • GC06P037301
  • GC06P036832
  • GC06P036913

Summaries for CLPSL1 Gene

GeneCards Summary for CLPSL1 Gene

CLPSL1 (Colipase Like 1) is a Protein Coding gene. GO annotations related to this gene include enzyme activator activity.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CLPSL1 Gene

Genomics for CLPSL1 Gene

Regulatory Elements for CLPSL1 Gene

Enhancers for CLPSL1 Gene
GeneHancer Identifier Score Enhancer Sources TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Other Gene Targets for Enhancer

Enhancers around CLPSL1 on UCSC Golden Path with GeneCards custom track

Genomic Location for CLPSL1 Gene

35,781,017 bp from pter
35,793,675 bp from pter
12,659 bases
Plus strand

Genomic View for CLPSL1 Gene

Genes around CLPSL1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CLPSL1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CLPSL1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CLPSL1 Gene

Proteins for CLPSL1 Gene

  • Protein details for CLPSL1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Colipase-like protein 1
    Protein Accession:
    Secondary Accessions:
    • A7E2T6
    • B2RPE2
    • B5G4V2
    • B6ZDM9
    • Q5T9G1

    Protein attributes for CLPSL1 Gene

    121 amino acids
    Molecular mass:
    14057 Da
    Quaternary structure:
    No Data Available
    • Sequence=ABK41022.1; Type=Frameshift; Positions=120; Evidence={ECO:0000305}; Sequence=CAI21640.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};

neXtProt entry for CLPSL1 Gene

Proteomics data for CLPSL1 Gene at MOPED

Post-translational modifications for CLPSL1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for CLPSL1 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for CLPSL1 Gene

Domains & Families for CLPSL1 Gene

Protein Domains for CLPSL1 Gene


Suggested Antigen Peptide Sequences for CLPSL1 Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the colipase family.
  • Belongs to the colipase family.
genes like me logo Genes that share domains with CLPSL1: view

No data available for Gene Families for CLPSL1 Gene

Function for CLPSL1 Gene

Phenotypes for CLPSL1 Gene

GenomeRNAi human phenotypes for CLPSL1:
genes like me logo Genes that share phenotypes with CLPSL1: view

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for CLPSL1 Gene

Localization for CLPSL1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for CLPSL1 Gene


Subcellular locations from

Jensen Localization Image for CLPSL1 Gene COMPARTMENTS Subcellular localization image for CLPSL1 gene
Compartment Confidence
extracellular 5

No data available for Gene Ontology (GO) - Cellular Components for CLPSL1 Gene

Pathways & Interactions for CLPSL1 Gene

SuperPathways for CLPSL1 Gene

No Data Available

Interacting Proteins for CLPSL1 Gene

Gene Ontology (GO) - Biological Process for CLPSL1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007586 digestion IEA --
genes like me logo Genes that share ontologies with CLPSL1: view

No data available for Pathways by source and SIGNOR curated interactions for CLPSL1 Gene

Drugs & Compounds for CLPSL1 Gene

No Compound Related Data Available

Transcripts for CLPSL1 Gene

mRNA/cDNA for CLPSL1 Gene

(1) REFSEQ mRNAs :
(6) Additional mRNA sequences :
(3) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for CLPSL1 Gene

Colipase-like 1:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for CLPSL1 Gene

No ASD Table

Relevant External Links for CLPSL1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for CLPSL1 Gene

mRNA expression in normal human tissues for CLPSL1 Gene

mRNA differential expression in normal tissues according to GTEx for CLPSL1 Gene

This gene is overexpressed in Pancreas (x50.7).

SOURCE GeneReport for Unigene cluster for CLPSL1 Gene Hs.131296

mRNA Expression by UniProt/SwissProt for CLPSL1 Gene

Tissue specificity: Exclusively expressed in epididymis, in the corpus region.
genes like me logo Genes that share expression patterns with CLPSL1: view

Primer Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression and Protein tissue co-expression partners for CLPSL1 Gene

Orthologs for CLPSL1 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for CLPSL1 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia CLPSL1 35
  • 97.22 (n)
  • 95.83 (a)
  • 98 (a)
Species with no ortholog for CLPSL1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for CLPSL1 Gene

Gene Tree for CLPSL1 (if available)
Gene Tree for CLPSL1 (if available)

Paralogs for CLPSL1 Gene

(1) SIMAP similar genes for CLPSL1 Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with CLPSL1: view

No data available for Paralogs for CLPSL1 Gene

Variants for CLPSL1 Gene

Sequence variations from dbSNP and Humsavar for CLPSL1 Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type
rs34109614 - 35,781,154(+) CTTCT(C/G/T)CTTTC reference, missense
rs1107894 -- 35,786,772(+) TGAGG(A/G)CACCA intron-variant
rs1326757 -- 35,780,476(+) gtgtg(A/C)cacca upstream-variant-2KB
rs6457850 -- 35,782,406(+) TGAAC(A/G)TGAGA intron-variant
rs6457852 -- 35,788,376(+) CCCCC(C/G)GGAAG downstream-variant-500B

Variation tolerance for CLPSL1 Gene

Residual Variation Intolerance Score: 82.9% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 2.39; 42.32% of all genes are more intolerant (likely to be disease-causing)

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Relevant External Links for CLPSL1 Gene

Disorders for CLPSL1 Gene

Relevant External Links for CLPSL1

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for CLPSL1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CLPSL1 Gene

Publications for CLPSL1 Gene

  1. Transcriptome analysis of a cDNA library from adult human epididymis. (PMID: 18390568) Li J.Y. … Zhang Y.L. (DNA Res. 2008) 3 4 67
  2. The BioPlex Network: A Systematic Exploration of the Human Interactome. (PMID: 26186194) Huttlin E.L. … Gygi S.P. (Cell 2015) 3
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3

Products for CLPSL1 Gene

Sources for CLPSL1 Gene