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Aliases for CLPSL1 Gene

Aliases for CLPSL1 Gene

  • Colipase-Like 1 2 3
  • C6orf127 3 4
  • Chromosome 6 Open Reading Frame 127 2
  • Colipase-Like Protein C6orf127 3
  • Colipase-Like Protein 1 3
  • DJ510O8.6 3
  • ESP32 3

External Ids for CLPSL1 Gene

Previous Symbols for CLPSL1 Gene

  • C6orf127

Summaries for CLPSL1 Gene

GeneCards Summary for CLPSL1 Gene

CLPSL1 (Colipase-Like 1) is a Protein Coding gene. GO annotations related to this gene include enzyme activator activity.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CLPSL1 Gene

Genomics for CLPSL1 Gene

Genomic Location for CLPSL1 Gene

Start:
35,781,017 bp from pter
End:
35,793,675 bp from pter
Size:
12,659 bases
Orientation:
Plus strand

Genomic View for CLPSL1 Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for CLPSL1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CLPSL1 Gene

No data available for Regulatory Elements for CLPSL1 Gene

Proteins for CLPSL1 Gene

  • Protein details for CLPSL1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    A2RUU4-COLL1_HUMAN
    Recommended name:
    Colipase-like protein 1
    Protein Accession:
    A2RUU4
    Secondary Accessions:
    • A7E2T6
    • B2RPE2
    • B5G4V2
    • B6ZDM9
    • Q5T9G1

    Protein attributes for CLPSL1 Gene

    Size:
    121 amino acids
    Molecular mass:
    14057 Da
    Quaternary structure:
    No Data Available
    SequenceCaution:
    • Sequence=ABK41022.1; Type=Frameshift; Positions=120; Evidence={ECO:0000305}; Sequence=CAI21640.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};

neXtProt entry for CLPSL1 Gene

Proteomics data for CLPSL1 Gene at MOPED

Post-translational modifications for CLPSL1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for CLPSL1 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for CLPSL1 Gene

Domains for CLPSL1 Gene

Protein Domains for CLPSL1 Gene

InterPro:
ProtoNet:

UniProtKB/Swiss-Prot:

COLL1_HUMAN
Family:
  • Belongs to the colipase family.:
    • A2RUU4
genes like me logo Genes that share domains with CLPSL1: view

No data available for Gene Families for CLPSL1 Gene

Function for CLPSL1 Gene

Gene Ontology (GO) - Molecular Function for CLPSL1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008047 enzyme activator activity IEA --
genes like me logo Genes that share ontologies with CLPSL1: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for CLPSL1 Gene

Localization for CLPSL1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for CLPSL1 Gene

Secreted.

Gene Ontology (GO) - Cellular Components for CLPSL1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005576 extracellular region IEA --
genes like me logo Genes that share ontologies with CLPSL1: view

Pathways for CLPSL1 Gene

SuperPathways for CLPSL1 Gene

No Data Available

Interacting Proteins for CLPSL1 Gene

Gene Ontology (GO) - Biological Process for CLPSL1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007586 digestion IEA --
GO:0016042 lipid catabolic process IEA --
GO:0043085 positive regulation of catalytic activity IEA --
genes like me logo Genes that share ontologies with CLPSL1: view

No data available for Pathways by source for CLPSL1 Gene

Transcripts for CLPSL1 Gene

mRNA/cDNA for CLPSL1 Gene

(1) REFSEQ mRNAs :
(6) Additional mRNA sequences :
(3) Selected AceView cDNA sequences:
(2) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for CLPSL1 Gene

Colipase-like 1:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for CLPSL1 Gene

No ASD Table

Relevant External Links for CLPSL1 Gene

GeneLoc Exon Structure for
CLPSL1
ECgene alternative splicing isoforms for
CLPSL1

Expression for CLPSL1 Gene

mRNA expression in normal human tissues for CLPSL1 Gene

mRNA differential expression in normal tissues according to GTEx for CLPSL1 Gene

This gene is overexpressed in Pancreas (50.7).

SOURCE GeneReport for Unigene cluster for CLPSL1 Gene Hs.131296

mRNA Expression by UniProt/SwissProt for CLPSL1 Gene

A2RUU4-COLL1_HUMAN
Tissue specificity: Exclusively expressed in epididymis, in the corpus region.
genes like me logo Genes that share expressions with CLPSL1: view

Orthologs for CLPSL1 Gene

This gene was present in the common ancestor of human and chimp.

Orthologs for CLPSL1 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia CLPSL1 36
  • 97.22 (n)
  • 95.83 (a)
CLPSL1 37
  • 98 (a)
OneToOne
Species with no ortholog for CLPSL1:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • cow (Bos Taurus)
  • dog (Canis familiaris)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for CLPSL1 Gene

ENSEMBL:
Gene Tree for CLPSL1 (if available)
TreeFam:
Gene Tree for CLPSL1 (if available)

Paralogs for CLPSL1 Gene

Selected SIMAP similar genes for CLPSL1 Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with CLPSL1: view

No data available for Paralogs for CLPSL1 Gene

Variants for CLPSL1 Gene

Sequence variations from dbSNP and Humsavar for CLPSL1 Gene

SNP ID Clin Chr 06 pos Sequence Context AA Info Type MAF
rs1107894 -- 35,786,772(+) TGAGG(A/G)CACCA intron-variant
rs1326757 -- 35,780,476(+) gtgtg(A/C)cacca upstream-variant-2KB
rs2766579 -- 35,781,282(+) TGAGC(A/G)GGCAT intron-variant
rs2766580 -- 35,782,013(+) tccca(A/C)agtgc intron-variant
rs2766581 -- 35,782,522(+) GTACA(A/G)CCAGG intron-variant

Relevant External Links for CLPSL1 Gene

HapMap Linkage Disequilibrium report
CLPSL1

No data available for Structural Variations from Database of Genomic Variants (DGV) for CLPSL1 Gene

Disorders for CLPSL1 Gene

No disorders were found for CLPSL1 Gene.

No data available for UniProtKB/Swiss-Prot for CLPSL1 Gene

Publications for CLPSL1 Gene

  1. Transcriptome analysis of a cDNA library from adult human epididymis. (PMID: 18390568) Li J.Y. … Zhang Y.L. (DNA Res. 2008) 3 4
  2. The DNA sequence and analysis of human chromosome 6. (PMID: 14574404) Mungall A.J. … Beck S. (Nature 2003) 4
  3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 4
  4. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3
  5. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3

Products for CLPSL1 Gene

  • QIAGEN qRT-PCR Assays for microRNAs that regulate CLPSL1
    • QuantiTect SYBR Green Assays in human,mouse,rat
    • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
    • QuantiFast Probe-based Assays in human,mouse,rat
    • Predesigned siRNA for gene silencing in human,mouse,rat for CLPSL1
    • Block miRNA regulation of CLPSL1 using miScript Target Protectors

    Sources for CLPSL1 Gene

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