CLN5 Gene
protein-coding GIFtS: 59
GCID: GC13P077564
|
|
ceroid-lipofuscinosis, neuronal 5
| |
Aliases
for CLN5 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Ceroid-Lipofuscinosis, Neuronal 51 2 | | NCL2 | | Ceroid-Lipofuscinosis Neuronal Protein 52 | | Protein CLN53 |
Export aliases for CLN5 gene to outside databasesPrevious GC identifers: GC13P075532 GC13P071559 GC13P076501 GC13P075362 GC13P076462 GC13P058263 |
Summaries
for CLN5 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for CLN5:
This gene is one of eight which have been associated with neuronal ceroid lipofuscinoses (NCL). Also referred to asBatten disease, NCL comprises a class of autosomal recessive, neurodegenerative disorders affecting children. Thegenes responsible likely encode proteins involved in the degradation of post-translationally modified proteins inlysosomes. The primary defect in NCL disorders is thought to be associated with lysosomal storage function.(providedby RefSeq, Oct 2008)
Gene Wiki entry for CLN5
|
Genomic Views
for CLN5 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000013.10 NC_018924.1 NT_024524.14
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the CLN5 gene promoter:
MEF-2A Sox5 AML1a Nkx2-2 Sox9 FOXD3 aMEF-2 HNF-3beta Gfi-1
Other transcription factors
Search SABiosciences Chromatin IP Primers for CLN5
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CLN5 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 13q21.1-q32 Ensembl cytogenetic band: 13q22.3 HGNC cytogenetic band: 13q21.2-q32CLN5 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 13 GeneLoc Exon Structure GeneLoc location for GC13P077564: view genomic region
(about GC identifiers)
Start:
|
77,564,795 bp from pter |
End:
|
77,576,652 bp from pter |
Size:
|
11,858 bases |
Orientation:
|
plus strand |
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Proteins
for CLN5 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: CLN5_HUMAN, O75503 (See
protein sequence)Recommended Name: Ceroid-lipofuscinosis neuronal protein 5 precursor Size: 358 amino acids; 41497 Da
Subcellular location: Lysosome
Sequence caution: Sequence=AAC27614.1; Type=Erroneous initiation; Note=Translation N-terminally shortened;Explore the universe of human proteins at neXtProt for CLN5: NX_O75503
Post-translational modifications:
Glycosylated1
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_O75503
CLN5 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_006484.1
ENSEMBL proteins: ENSP00000366673
Human Recombinant Protein Products:
Gene Ontology (GO): 5/7 cellular component terms (GO ID links to tree view) (see all 7): About this table
CLN5 for ontologies About GeneDecksing
CLN5 Antibody Products:
Assay Products for CLN5: |
Protein
Domains /
Families
for CLN5 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
CLN5 for domains About GeneDecksing
1 InterPro domain/family:Graphical View of Domain Structure for InterPro Entry O75503ProtoNet protein and cluster: O75503 UniProtKB/Swiss-Prot: CLN5_HUMAN, O75503Similarity: Belongs to the CLN5 family |
Function
for CLN5 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
Genatlas biochemistry entry for CLN5:putative lysosomal membrane protein,ubiquitously expressed,in adult and fetal tissues
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CLN5 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CLN5
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: CLN5 (NM_006493) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CLN5 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CLN5 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CLN5 |
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table
CLN5 for ontologies About GeneDecksing
4 GenomeRNAi human phenotypes for CLN5:
Animal Models:
Mouse knock-out Cln5tm1Pltn for CLN5
2 MGI mutant phenotypes (inferred from 1 allele ) (MGI details for Cln5):
CLN5 for phenotypes About GeneDecksing
|
Pathways & Interactions
for CLN5 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Lysosome | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1 
Kegg Pathway (Kegg details for CLN5):
CLN5 for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for CLN5
STRING Interaction
Network Preview (showing 2 interactants - click image to see more details)
3 Interacting proteins for CLN5 (O755031, 2, 3 ENSP000003666734) via UniProtKB, MINT, STRING, and/or I2DAbout this table
Gene Ontology (GO): 5/10 biological process terms (GO ID links to tree view) (see all 10): About this table
CLN5 for ontologies About GeneDecksing
|
Drugs & Compounds
for CLN5 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for CLN5
Search CenterWatch for drugs/clinical trials and news about CLN5
|
Transcripts
for CLN5 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for CLN5 gene: NM_006493.2 Unigene Cluster for CLN5: Ceroid-lipofuscinosis, neuronal 5 Hs.30213 [show with all ESTs]Unigene Representative Sequence: AF0682272 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000377453(uc001vkc.3) ENST00000485938
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CLN5 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CLN5
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: CLN5 (NM_006493) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CLN5 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CLN5 |
Additional cDNA sequence: AF068227.1 AK075109.1 AK304001.1 8 DOTS entries: DT.75180488 DT.100781098 DT.92462143 DT.402712 DT.120781358 DT.102825063 DT.95309114 DT.92365650 24/156 AceView cDNA sequences (see all 156): BI962915 NM_006493 AI370647 AI359422 BM978657 BM849262 BM725741 BQ021733 AF068227 CA431029 BI090566 BM757757 AI284529 AA306653 BQ417448 AU280382 BU633296 BQ670758 BM929550 BM930794 AI767299 AL546472 AI393484 AI654635
GeneLoc Exon Structure
4 Alternative Splicing Database (ASD) splice patterns (SP) for CLN5 About this scheme
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | ^ | 2 | ^ | 3 | ^ | 4a | · | 4b | · | 4c | ^ | 5 | ^ | 6 |
|---|
|
| SP1: | | | | | | | | | | | - | | | | | | - | | - | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | - | | | | | | - | | | | | | |
| SP4: | | | | | | | | | | | - | | | | | | | | | | | |
ECgene alternative splicing isoforms for CLN5
|
Expression
for CLN5 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| CLN5 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: GCTGCAGACA
About this image
See CLN5 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for CLN5
SOURCE GeneReport for Unigene cluster: Hs.30213
UniProtKB/Swiss-Prot: CLN5_HUMAN, O75503Tissue specificity: Ubiquitous
SABiosciences Custom PCR Arrays for CLN5
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CLN5
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat CLN5 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CLN5 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CLN5 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CLN5 |
Orthologs
for CLN5 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for CLN5 gene from 5/12 species (see all 12) About this table
ENSEMBL Gene Tree for CLN5 (if available)
TreeFam Gene Tree for CLN5 (if available) |
Paralogs
for CLN5 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for CLN5 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 13 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for CLN5 (77564795 - 77576652 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for CLN5: --
Human Gene Mutation Database (HGMD): CLN5
Locus Specific Mutation Databases (LSDB): CLN5
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CLN5 |
|
Disorders
/ Diseases
for CLN5 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
CLN5 for disorders About GeneDecksing
OMIM gene information: 608102
OMIM disorders: 256731
UniProtKB/Swiss-Prot: CLN5_HUMAN, O75503
Defects in CLN5 are the cause of neuronal ceroid lipofuscinosis type 5 (CLN5) [MIM:256731]; also known asFinnish variant late-infantile neuronal ceroid lipofuscinosis (vLINCL). A form of neuronal ceroid lipofuscinosis.Neuronal ceroid lipofuscinoses are progressive neurodegenerative, lysosomal storage diseases characterized byintracellular accumulation of autofluorescent liposomal material, and clinically by seizures, dementia, visual loss,and/or cerebral atrophy. The lipopigment patterns observed most often in neuronal ceroid lipofuscinosis type 5comprise mixed combinations of granular, curvilinear, and fingerprint profiles
20/22  diseases for CLN5 (see all 22): About MalaCardsneuronal ceroid-lipofuscinoses ceroid lipofuscinosis ceroid lipofuscinosis neuronal 5 ceroid-lipofuscinosis, neuronal-5, variant late infantile
batten disease neuronitis neuronal ceroid-lipofuscinosis myoclonus epilepsy
progressive myoclonus epilepsy lysosomal storage disease myoclonus peripheral retinal degeneration
retinal degeneration intellectual disability neurodegenerative disease brain disease
cerebral atrophy epilepsy syndrome dementia retinitis
2 diseases from the University of Copenhagen DISEASES database for CLN5:Neuronal ceroid lipofuscinosis Blindness 10/12 Novoseek disease relationships for CLN5 gene (see all 12) About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| ceroid lipofuscinosis, neuronal, late infantile, variant |
98 |
5 |
10419622 (2), 9662406 (1), 10953198 (1), 10480355 (1) |
| neuronal ceroid lipofuscinoses |
97.1 |
8 |
10992246 (2), 16839750 (1), 18850119 (1), 19084560 (1) (see all 6) |
| lincl |
95.8 |
28 |
9097964 (2), 9458173 (1), 18850119 (1), 19385065 (1) (see all 12) |
| neurodegenerative diseases |
75.9 |
4 |
18850119 (2), 19177532 (1) |
| batten disease |
64.3 |
2 |
11579433 (1) |
| epilepsy |
53.5 |
3 |
17607606 (1), 19084560 (1), 20052765 (1) |
| neuron loss |
50.7 |
1 |
19084560 (1) |
| encephalopathy |
45.9 |
1 |
17607606 (1) |
| brain diseases |
31.8 |
1 |
10480355 (1) |
| atrophy |
23.5 |
1 |
11579433 (1) |
Genatlas disease: CLN5 ceroid-lipofuscinosis,neuronal 5,late infantile,Jansky-Bielschowsky disease variant,characterized by an onset fiveyears motor clumsiness,followed by progressive visual failure with macular and peripheral retinal degeneration,mentaland motor deterioration and later by myoclonia and siezures,including the Finnish variant with an onset between 13 or30 years
GeneTests: CLN5
Neuronal Ceroid-Lipofuscinoses
Human Genome Epidemiology (HuGE) Navigator: CLN5 (2 documents)
Export disorders for CLN5 gene to outside databases
|
Publications
for CLN5 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for CLN5 gene, integrated from 9 sources (see all 65):
(articles sorted by number of sources associating them with CLN5) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Two novel CLN5 mutations in a Portuguese patient with vLINCL: insights into molecular mechanisms of CLN5 deficiency. (PubMed id 16814585)1, 2, 9 Bessa C.... Ribeiro M.G. (2006)
- Retention of lysosomal protein CLN5 in the endoplasmic reticulum causes neuronal ceroid lipofuscinosis in Asian sibship. (PubMed id 19309691)1, 2, 9 Lebrun A.-H.... Schulz A. (2009)
- Revelation of a novel CLN5 mutation in early juvenile neuronal ceroid lipofuscinosis. (PubMed id 17607606)1, 2, 9 Cannelli N....Santorelli F.M. (2007)
- Lysosomal localization of the neuronal ceroid lipofuscinosis CLN5 protein. (PubMed id 11971870)1, 2, 9 Isosomppi J.... Peltonen L. (2002)
- CLN5, a novel gene encoding a putative transmembrane protein mutated in Finnish variant late infantile neuronal ceroid lipofuscinosis. (PubMed id 9662406)1, 2, 9 Savukoski M....Peltonen L. (1998)
- A CLN5 mutation causing an atypical neuronal ceroid lipofuscinosis of juvenile onset. (PubMed id 15728307)1, 2 Pineda-Trujillo N....Ruiz-Linares A. (2005)
- Efficient construction of a physical map by fiber-FISH of the CLN5 region: refined assignment and long-range contig covering the critical region on 13q22. (PubMed id 8661106)1, 3 Klockars T....Peltonen L. (1996)
- Defined chromosomal assignment of CLN5 demonstrates that at least four genetic loci are involved in the pathogenesis of human ceroid lipofuscinoses. (PubMed id 7942847)1, 3 Savukoski M....Peltonen L. (1994)
- Novel interactions of CLN5 support molecular networki ng between Neuronal Ceroid Lipofuscinosis proteins. (PubMed id 19941651)1, 9 Lyly A....KyttAolAo A. (2009)
- The neuronal ceroid lipofuscinosis protein CLN5: new insights into cellular maturation, transport, and consequences of mutations. (PubMed id 20052765)1, 9 Schmiedt M.L....KyttAolAo A. (2010)
|
External Searches for CLN5 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing CLN5 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing CLN5 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing CLN5 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for CLN5 | Pharmacogenomics, SNPs, Pathways | | NCL CLN5 | http://www.ucl.ac.uk/ncl/cln5.shtml | | GeneReviews | http://www.ncbi.nlm.nih.gov/sites/GeneTests/lab/gene/CLN5 |
|
| | |
About This Section
| Patent Information for CLN5 gene:
Search GeneIP for patents involving CLN5
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for CLN5 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
 | |
 | |
 |
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variant library, vector shuttling | | | OriGene Custom Antibody Services for CLN5 | | OriGene Custom Protein Services for CLN5 | | | OriGene Custom Immunoassay Development | | |
| |
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 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat CLN5 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CLN5 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CLN5 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CLN5 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CLN5 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CLN5 |
| |
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| |  |  |  |  | | | | |
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 | | | CLN5 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CLN5 |
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| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CLN5 |
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