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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

CLIP3 Gene

protein-coding   GIFtS: 47
GCID: GC19M036505

CAP-GLY Domain Containing Linker Protein 3

  Search for CLIP3
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
CAP-GLY Domain Containing Linker Protein 31 2     CLIP-170-Related 59 KDa Protein2 3
CLIPR592 3 5     CLIP-170-related1
Restin-Like 11 2     RSNL12
Cytoplasmic Linker Protein 170-Related 59 KDa Protein2 3     CAP-Gly Domain-Containing Linker Protein 32
CLIPR-592 3     

External Ids:    HGNC: 243141   Entrez Gene: 259992   Ensembl: ENSG000001052707   OMIM: 6073825   UniProtKB: Q96DZ53   

Export aliases for CLIP3 gene to outside databases

Previous GC identifers: GC19M041198 GC19M033011


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for CLIP3 Gene:
This gene encodes a member of the cytoplasmic linker protein 170 family. Members of this protein family contain a
cytoskeleton-associated protein glycine-rich domain and mediate the interaction of microtubules with cellular
organelles. The encoded protein plays a role in T cell apoptosis by facilitating the association of tubulin and
the lipid raft ganglioside GD3. The encoded protein also functions as a scaffold protein mediating membrane
localization of phosphorylated protein kinase B. Alternatively spliced transcript variants have been observed for
this gene. (provided by RefSeq, Dec 2010)

GeneCards Summary for CLIP3 Gene: 
CLIP3 (CAP-GLY domain containing linker protein 3) is a protein-coding gene. GO annotations related to this gene include microtubule binding and ganglioside binding. An important paralog of this gene is CLIP2.

UniProtKB/Swiss-Prot: CLIP3_HUMAN, Q96DZ5
Function: Functions as a cytoplasmic linker protein. Involved in TGN-endosome dynamics




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000019.9  NC_018930.2  NT_011109.16  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the CLIP3 gene promoter:
         MAZR   MyoD   Lmo2   FOXO3   E47   FOXO3b   HOXA5   FOXO1a   FOXO3a   FOXO1   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCLIP3 promoter sequence
   Search SABiosciences Chromatin IP Primers for CLIP3

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CLIP3


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 19q13.12   Ensembl cytogenetic band:  19q13.12   HGNC cytogenetic band: 19q13

CLIP3 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CLIP3 gene location

GeneLoc information about chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19M036505:  view genomic region     (about GC identifiers)

Start:
36,505,562 bp from pter      End:
36,524,245 bp from pter
Size:
18,684 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: CLIP3_HUMAN, Q96DZ5 (See protein sequence)
Recommended Name: CAP-Gly domain-containing linker protein 3  
Size: 547 amino acids; 59560 Da
Subunit: Homodimer
Subcellular location: Cytoplasm. Golgi apparatus, Golgi stack. Note=Localized to Golgi stacks as well as on
tubulovesicular elements juxtaposed to Golgi cisternae
Miscellaneous: The N-terminal half is dispensable for proper Golgi targeting, whereas the GoLD region is required
1 PDB 3D structure from and Proteopedia for CLIP3:
2CP0 (3D)    
Secondary accessions: A8K0E4 Q8WWL1 Q96C99 Q9UFT7

Explore the universe of human proteins at neXtProt for CLIP3: NX_Q96DZ5

Explore proteomics data for CLIP3 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q96DZ5

  • CLIP3 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    CLIP3 Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_001186499.1  NP_056341.1  

    ENSEMBL proteins: 
     ENSP00000353732   ENSP00000466832   ENSP00000468689   ENSP00000466026  

    Human Recombinant Protein Products for CLIP3: 
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    OriGene Protein Over-expression Lysate for CLIP3
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    OriGene Custom Protein Services for CLIP3
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    Novus Biologicals CLIP3 Protein
    Novus Biologicals CLIP3 Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for CLIP3 

    Gene Ontology (GO): 5/7 cellular component terms (GO ID links to tree view) (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005795Golgi stack IEA--
    GO:0005802trans-Golgi network ISS--
    GO:0005886plasma membrane IMP15262990
    GO:0031901early endosome membrane IDA11854307
    GO:0032588trans-Golgi network membrane IMP15262990

    CLIP3 for ontologies           About GeneDecksing



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    LSBio Antibodies in human, mouse, rat for CLIP3 

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    Cloud-Clone Corp. CLIAs for CLIP3


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    ANKRD: Ankyrin repeat domain containing

    3 InterPro protein domains:
     IPR000938 CAP-Gly_domain
     IPR002110 Ankyrin_rpt
     IPR020683 Ankyrin_rpt-contain_dom

    Graphical View of Domain Structure for InterPro Entry Q96DZ5

    ProtoNet protein and cluster: Q96DZ5

    2 Blocks protein domains:
    IPB000938 CAP-Gly domain
    IPB002110 Ankyrin repeat signature


    UniProtKB/Swiss-Prot: CLIP3_HUMAN, Q96DZ5
    Domain: Microtubule association is inhibited by the ANK repeats and the Golgi localization region (GoLD)
    Similarity: Contains 3 ANK repeats
    Similarity: Contains 2 CAP-Gly domains


    CLIP3 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: CLIP3_HUMAN, Q96DZ5
    Function: Functions as a cytoplasmic linker protein. Involved in TGN-endosome dynamics

         Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
    GO:0008017microtubule binding IMP--
    GO:0035594ganglioside binding IDA--
         
    CLIP3 for ontologies           About GeneDecksing


    Phenotypes:
         5 MGI mutant phenotypes (inferred from 1 allele(MGI details for Clip3):
     homeostasis/metabolism  mortality/aging  muscle  nervous system  respiratory system 

    CLIP3 for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Clip3tm1.1Ics for CLIP3

       inGenious Targeting Laboratory - Custom generated mouse model solutions for CLIP3 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for CLIP3

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for CLIP3 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for CLIP3 

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat CLIP3
    8/45 QIAGEN miScript miRNA Assays for microRNAs that regulate CLIP3 (see all 45):
    hsa-miR-3938 hsa-miR-3607-3p hsa-miR-300 hsa-miR-1914* hsa-miR-485-3p hsa-miR-486-3p hsa-miR-624 hsa-miR-4314
    SwitchGear 3'UTR luciferase reporter plasmidCLIP3 3' UTR sequence
    Inhib. RNA
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    Gene Editing
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                         Customized lentivirus expression plasmids for stable overexpression of CLIP3 

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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CLIP3


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CLIP3

    STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

    5/6 Interacting proteins for CLIP3 (Q96DZ53 ENSP000003537324) via UniProtKB, MINT, STRING, and/or I2D (see all 6)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    PRKCGP051293I2D: score=2 
    AKT1P317493I2D: score=1 
    AKT2P317513I2D: score=1 
    WNK1Q9H4A33I2D: score=1 
    HDAC2ENSP000003813314STRING: ENSP00000381331
    About this table

    Gene Ontology (GO): 5/10 biological process terms (GO ID links to tree view) (see all 10):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0001934positive regulation of protein phosphorylation ISS--
    GO:0010828positive regulation of glucose transport ISS--
    GO:0018230peptidyl-L-cysteine S-palmitoylation IMP15262990
    GO:0031115negative regulation of microtubule polymerization IMP15262990
    GO:0043065positive regulation of apoptotic process IMP--

    CLIP3 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for CLIP3

    Search CenterWatch for drugs/clinical trials and news about CLIP3

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for CLIP3 gene (2 alternative transcripts): 
    NM_001199570.1  NM_015526.2  

    Unigene Cluster for CLIP3:

    CAP-GLY domain containing linker protein 3
    Hs.466539  [show with all ESTs]
    Unigene Representative Sequence: NM_001199570
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000360535(uc010eeq.2 uc002ocz.2) ENST00000593074 ENST00000585466
    ENST00000592017 ENST00000590559 ENST00000586457
    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat CLIP3
    8/45 QIAGEN miScript miRNA Assays for microRNAs that regulate CLIP3 (see all 45):
    hsa-miR-3938 hsa-miR-3607-3p hsa-miR-300 hsa-miR-1914* hsa-miR-485-3p hsa-miR-486-3p hsa-miR-624 hsa-miR-4314
    SwitchGear 3'UTR luciferase reporter plasmidCLIP3 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
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    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CLIP3
    Clone
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    Sirion Biotech Customized lentivirus for stable overexpression of CLIP3 
                         Customized lentivirus expression plasmids for stable overexpression of CLIP3 
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    OriGene qPCR primer pairs and template standards for CLIP3
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CLIP3
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CLIP3

    Additional mRNA sequence: 

    AJ427922.1 AK056445.1 AK090732.1 AK092354.1 AK094738.1 AK289509.1 AK294748.1 AL110254.1 
    AL117468.1 BC013116.1 BC014486.1 BC128090.1 

    18 DOTS entries:

    DT.100814048  DT.100814049  DT.100769524  DT.92041890  DT.450253  DT.95312646  DT.100814050  DT.95312599 
    DT.121465224  DT.121465243  DT.121465280  DT.92418511  DT.102833405  DT.121465241  DT.121465290  DT.121465301 
    DT.95209940  DT.99963088 

    24/257 AceView cDNA sequences (see all 257):

    BQ670139 BQ636741 BQ006250 BP347330 AK094738 AL117468 AI218217 AI914439 
    AX747495 CB155136 BC013116 BF507551 BM708969 AI288440 BU734958 T32142 
    BM699707 CB156703 AK056445 CF243058 BQ718970 CB155654 AA969904 BQ574329 

    GeneLoc Exon Structure

    3 Alternative Splicing Database (ASD) splice patterns (SP) for CLIP3    About this scheme

    ExUns: 1a · 1b ^ 2a · 2b ^ 3 ^ 4 ^ 5 ^ 6 ^ 7 ^ 8a · 8b · 8c ^ 9 ^ 10a · 10b ^ 11 ^ 12 ^ 13 ^ 14 ^ 15a · 15b
    SP1:                                                                                                                              
    SP2:                    -     -     -     -     -     -     -                                                                     
    SP3:                          -     -     -     -     -     -     -                                                               


    ECgene alternative splicing isoforms for CLIP3

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    CLIP3 expression in normal human tissues (normalized intensities)      CLIP3 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: ACTCCTGTCC
    CLIP3 Expression
    About this image


    CLIP3 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/3 selected tissues (see all 3) fully expand
     
     Pancreas (Endocrine System)    fully expand to see all 4 entries
             Endocrine Progenitor Cells Ventral Pancreatic Bud
     
     Primitive Streak (Early Embryonic Tissues)
             Mesendoderm-like cells ( Generation of mesendoderm and definitive endoderm cells...
     
     Brain (Nervous System)

    See CLIP3 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for CLIP3

    SOURCE GeneReport for Unigene cluster: Hs.466539
        SABiosciences Custom PCR Arrays for CLIP3
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CLIP3

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of animals and fungi.

    Orthologs for CLIP3 gene from 4/12 species (see all 12)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Clip31 , 5 CAP-GLY domain containing linker protein 31, 5 89.34(n)1
    98.54(a)1
      7 (17.37 cM)5
    766861  NM_001081114.11  NP_001074583.11 
     302916725 
    lizard
    (Anolis carolinensis)
    Reptilia CLIP36
    Uncharacterized protein
    59(a)
    1 ↔ 1
    GL344980.1(3161-14728)
    zebrafish
    (Danio rerio)
    Actinopterygii LOC5624501 similar to LOC495693 protein 71.62(n)
    78.95(a)
      562450  XM_685830.5  XP_690922.4 
    baker's yeast
    (Saccharomyces cerevisiae)
    Saccharomycetes ALF16
    Alpha-tubulin folding protein, similar to mammalia...
    15(a)
    1 → many
    XIV(349907-350671)


    ENSEMBL Gene Tree for CLIP3 (if available)
    TreeFam Gene Tree for CLIP3 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for CLIP3 gene
    CLIP22  CEP3502  CLIP42  CLIP12  
    2 SIMAP similar genes for CLIP3 using alignment to 3 protein entries:     CLIP3_HUMAN (see all proteins):
    CLIP4    FLJ21069

    CLIP3 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/409 SNPs in CLIP3 are shown (see all 409)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 19 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1925890651,2
    C--36507156(+) GGCAGA/C/TGGGGA 2 -- int10--------
    rs1830898351,2
    --36507242(+) TGGCTA/GTGGTT 2 -- int10--------
    rs1505453761,2
    C--36507244(+) CTGTG-/GTGTTTG 2 -- int10--------
    rs1415773761,2
    --36507301(+) CTGGAA/GTGCCA 2 -- int10--------
    rs118814281,2
    C,F,A,H--36507319(+) ATCTCA/GGCTCA 2 -- int13Minor allele frequency- G:0.17NA WA CSA 6
    rs1883708351,2
    --36507375(+) CTCCCA/GAGTAG 2 -- int10--------
    rs1926823411,2
    --36507497(+) CGCCTC/GCCTTG 2 -- int10--------
    rs1845074931,2
    --36507542(+) ACCCCG/TCCCGG 2 -- int10--------
    rs1379537071,2
    --36507612(+) CCCACC/TCGAAA 2 -- int10--------
    rs1156632421,2
    F--36507651(+) CCCTAC/TACCCT 2 -- int11Minor allele frequency- T:0.01WA 118

    HapMap Linkage Disequilibrium report for CLIP3 (36505562 - 36524245 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 5 variations for CLIP3:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv1000212CNV Deletion20482838
    nsv911641CNV Loss21882294
    nsv833815CNV Loss17160897
    dgv51n68CNV Loss17160897
    nsv911638CNV Loss21882294

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    CLIP3 for disorders           About MalaCards
    OMIM gene information: 607382    OMIM disorders: --


    CLIP3 for disorders           About GeneDecksing


    Export disorders for CLIP3 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for CLIP3 gene, integrated from 9 sources (see all 13):
    (articles sorted by number of sources associating them with CLIP3)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. CLIPR-59, a new trans-Golgi/TGN cytoplasmic linker protein belonging to the CLIP-170 family. (PubMed id 11854307)1, 2, 3 Perez F....Goud B. (2002)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    4. ClipR-59 interacts with Akt and regulates Akt cellular compartmentalization. (PubMed id 19139280)1, 9 Ding J. and Du K. (2009)
    5. CLIPR-59 is a lipid raft-associated protein containing a cytoskeleton-associated protein glycine-rich domain (CAP-Gly) that perturbs microtubule dynamics. (PubMed id 15262990)1, 9 Lallemand-Breitenbach V....Perez F. (2004)
    6. Methods for quantification of in vivo changes in prote in ubiquitination following proteasome and deubiquitinase inhibition. (PubMed id 22505724)1 Udeshi N.D....Carr S.A. (2012)
    7. Functional dissection of lysine deacetylases reveals t hat HDAC1 and p300 regulate AMPK. (PubMed id 22318606)1 Lin Y.Y....Boeke J.D. (2012)
    8. CLIPR-59 regulates TNF-a-induced apoptosis by controll ing ubiquitination of RIP1. (PubMed id 22297296)1 Fujikura D....Miyazaki T. (2012)
    9. Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
    10. Role of GD3-CLIPR-59 association in lymphoblastoid T cell apoptosis triggered by CD95/Fas. (PubMed id 20052288)1 Sorice M....Malorni W. (2010)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 25999 HGNC: 24314 AceView: CLIPR-59 Ensembl:ENSG00000105270 euGenes: HUgn25999
    ECgene: CLIP3 H-InvDB: CLIP3

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for CLIP3 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for CLIP3 gene:
    Search GeneIP for patents involving CLIP3

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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