Aliases for CLIP3 Gene
External Ids for CLIP3 Gene
Previous GeneCards Identifiers for CLIP3 Gene
This gene encodes a member of the cytoplasmic linker protein 170 family. Members of this protein family contain a cytoskeleton-associated protein glycine-rich domain and mediate the interaction of microtubules with cellular organelles. The encoded protein plays a role in T cell apoptosis by facilitating the association of tubulin and the lipid raft ganglioside GD3. The encoded protein also functions as a scaffold protein mediating membrane localization of phosphorylated protein kinase B. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Dec 2010]
GeneCards Summary for CLIP3 Gene
CLIP3 (CAP-GLY Domain Containing Linker Protein 3) is a Protein Coding gene. GO annotations related to this gene include microtubule binding and ganglioside binding. An important paralog of this gene is CLIP4.
UniProtKB/Swiss-Prot for CLIP3 Gene
Functions as a cytoplasmic linker protein. Involved in TGN-endosome dynamics. May modulate the cellular compartmentalization of AKT kinase family and promote its cell membrane localization, thereby playing a role in glucose transport in adipocytes.