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CLEC6A Gene

protein-coding   GIFtS: 47
GCID: GC12P008608

C-Type Lectin Domain Family 6, Member A

(Previous names: C-type (calcium dependent, carbohydrate-recognition domain)...)
(Previous symbol: CLECSF10)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
C-Type Lectin Domain Family 6, Member A1 2     CLEC4N2 5
CLECSF101 2 3     C-Type Lectin Domain Family 6 Member A2
C-Type (Calcium Dependent, Carbohydrate-Recognition Domain) Lectin,
Superfamily Member 101 2
     Dectin 22
Dendritic Cell-Associated C-Type Lectin 22 3     dectin-22
C-Type Lectin Superfamily Member 102 3     DECTIN23
DC-Associated C-Type Lectin 22 3     Dectin-23

External Ids:    HGNC: 145561   Entrez Gene: 939782   Ensembl: ENSG000002058467   OMIM: 6135795   UniProtKB: Q6EIG73   

Export aliases for CLEC6A gene to outside databases

Previous GC identifers: GC12U900496 GC12P008499 GC12P008391


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for CLEC6A Gene:
Like dectin-1 (CLEC7A; MIM 606264), CLEC6A, or dectin-2, is a type II membrane receptor with an extracellular
C-type lectin-like domain fold. However, unlike dectin-1, dectin-2 lacks an immunoreceptor tyrosine-based
activation motif (ITAM) in its cytoplasmic domain (Kanazawa et al., 2004 (PubMed 15175046)).(supplied by OMIM,
Nov 2010)

GeneCards Summary for CLEC6A Gene:
CLEC6A (C-type lectin domain family 6, member A) is a protein-coding gene. Diseases associated with CLEC6A include superficial mycosis, and job's syndrome. GO annotations related to this gene include carbohydrate binding. An important paralog of this gene is CD207.

UniProtKB/Swiss-Prot: CLC6A_HUMAN, Q6EIG7
Function: Binds high-mannose carbohydrates in a Ca(2+)-dependent manner. Functional receptor for alpha-mannans on
C.albicans hypheas. Plays an important role in the host defense against C.albicans infection by inducing TH17
cell differentiation. Recognizes also, in a mannose-dependent manner, allergens from house dust mite and fungi,
by promoting cysteinyl leukotriene production. Recognizes soluble elements from the eggs of Shistosoma mansoni
altering adaptive immune responses. Transduces signals through an Fc receptor gamma chain /FCER1G and
Syk-CARD9-NF-kappa-B-dependent pathway (By similarity)




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000012.12  NC_018923.2  NT_009714.18  
Regulatory elements:
   Regulatory transcription factor binding sites in the CLEC6A gene promoter:
         Nkx3-1 v4   Tal-1   AML1a   NRSF form 1   RREB-1   NRSF form 2   E47   MZF-1   c-Myb   Pax-4a   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCLEC6A promoter sequence
   Search Chromatin IP Primers for CLEC6A

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat CLEC6A


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12p13   Ensembl cytogenetic band:  12p13.31   HGNC cytogenetic band: 12p13

CLEC6A Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CLEC6A gene location

GeneLoc information about chromosome 12         GeneLoc Exon Structure

GeneLoc location for GC12P008608:  view genomic region     (about GC identifiers)

Start:
8,608,522 bp from pter      End:
8,630,926 bp from pter
Size:
22,405 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
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UniProtKB/Swiss-Prot: CLC6A_HUMAN, Q6EIG7 (See protein sequence)
Recommended Name: C-type lectin domain family 6 member A  
Size: 209 amino acids; 23998 Da
Subunit: Associated with FCER1G (By similarity)
Secondary accessions: A2RUK3
Alternative splicing: 2 isoforms:  Q6EIG7-1   Q6EIG7-2   

Explore the universe of human proteins at neXtProt for CLEC6A: NX_Q6EIG7

Post-translational modifications: 

  • Glycosylation2 at Asn131, Asn170
  • REFSEQ proteins: NP_001007034.1  
    ENSEMBL proteins: 
     ENSP00000371505  

    CLEC6A Human Recombinant Protein Products:

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    CLEC6A Antibody Products:

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    Cloud-Clone Corp. CLIAs for CLEC6A


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    CLEC: C-type lectin domain containing

    3 InterPro protein domains:
     IPR016187 C-type_lectin_fold
     IPR016186 C-type_lectin-like
     IPR001304 C-type_lectin

    Graphical View of Domain Structure for InterPro Entry Q6EIG7

    ProtoNet protein and cluster: Q6EIG7

    1 Blocks protein domain: IPB002353 Type II antifreeze protein signature

    UniProtKB/Swiss-Prot: CLC6A_HUMAN, Q6EIG7
    Domain: A short stretch of the intracellular domain (AA 8-14) proximal to the transmembrane domain is required for
    association with Fc receptor gamma chain (By similarity)
    Similarity: Contains 1 C-type lectin domain


    CLEC6A for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: CLC6A_HUMAN, Q6EIG7
    Function: Binds high-mannose carbohydrates in a Ca(2+)-dependent manner. Functional receptor for alpha-mannans on
    C.albicans hypheas. Plays an important role in the host defense against C.albicans infection by inducing TH17
    cell differentiation. Recognizes also, in a mannose-dependent manner, allergens from house dust mite and fungi,
    by promoting cysteinyl leukotriene production. Recognizes soluble elements from the eggs of Shistosoma mansoni
    altering adaptive immune responses. Transduces signals through an Fc receptor gamma chain /FCER1G and
    Syk-CARD9-NF-kappa-B-dependent pathway (By similarity)
    Induction: Up-regulated by granulocyte-macrophage colony-stimulating factor (GM-CSF), TGF-beta 1, TNF-alpha and
    down-regulated by IL-4, IL-10 or UVB in CD14+ monocytes

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding ----
    GO:0030246carbohydrate binding ISS--
         
    CLEC6A for ontologies           About GeneDecksing


    Phenotypes:
         4 MGI mutant phenotypes (inferred from 1 allele(MGI details for Clec4n):
     hematopoietic system  immune system  mortality/aging  renal/urinary system 

    CLEC6A for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Clec4ntm1Yiw for CLEC6A

       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for CLEC6A
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       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for CLEC6A
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for CLEC6A

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    Sino Biological Human cDNA Clone for CLEC6A
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CLEC6A

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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CLEC6A


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    CLC6A_HUMAN, Q6EIG7: Membrane; Single-pass type II membrane protein (Probable)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    plasma membrane3
    extracellular2

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016021integral component of membrane IEA--

    CLEC6A for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for CLEC6A About                                                                                                See pathways by source

    SuperPathContained pathways About
    1NOD-like Receptor Signaling Pathways
    Pathogen or Damage-activated C-Type Lectin Receptor Signaling Pathways0.31

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways

    1 R&D Systems Pathway for CLEC6A
        Pathogen or Damage-activated C-Type Lectin Receptor Signaling Pathways




        Pathway & Disease-focused RT2 Profiler PCR Array including CLEC6A: 
              Antifungal Response in human mouse rat

    Interactions:

        Search GeneGlobe Interaction Network for CLEC6A

    Gene Ontology (GO): 4 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0043123positive regulation of I-kappaB kinase/NF-kappaB signaling ISS--
    GO:0045087innate immune response ISS--
    GO:0050715positive regulation of cytokine secretion ISS--
    GO:0050832defense response to fungus ISS--

    CLEC6A for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for CLEC6A (CLC6A)



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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    REFSEQ mRNAs for CLEC6A gene: 
    NM_001007033.1  

    Unigene Cluster for CLEC6A:

    C-type lectin domain family 6, member A
    Hs.591147  [show with all ESTs]
    Unigene Representative Sequence: AY321309
    1 Ensembl transcript including schematic representation, and UCSC links where relevant:
    ENST00000382073(uc001qum.1)
    miRNA
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    Primer
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      QuantiTect SYBR Green Assays in human, mouse, rat CLEC6A
      QuantiFast Probe-based Assays in human, mouse, rat CLEC6A

    Additional mRNA sequence: 

    AK308011.1 AY321309.1 AY365135.1 BC132933.1 BC132935.1 

    1 DOTS entry:

    DT.121175086 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    CLEC6A expression in normal human tissues (normalized intensities)      CLEC6A embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GCTGGCAACT
    CLEC6A Expression
    About this image


    CLEC6A expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 3) fully expand
     
     Blood (Cardiovascular System)    fully expand to see all 3 entries
             Monocytes Peripheral Blood
     
     Bone (Muscoskeletal System)
             Zeugopod Periosteum
     
     Lateral Plate Mesoderm (Gastrulation Derivatives)
             Hematopoietic Stem Cells Aorta-Gonad-Mesonephros
    CLEC6A Protein expression data from MOPED1, PaxDb2 and MaxQB3 --

    SOURCE GeneReport for Unigene cluster: Hs.591147

    UniProtKB/Swiss-Prot: CLC6A_HUMAN, Q6EIG7
    Tissue specificity: Expressed in lung, spleen, lymph node, leukocytes, bone marrow, tonsils and dendritic cells.
    Strongly expressed in purified monocytes and weakly in B-cells. In peripheral blood cells, preferentially
    expressed in plasmacytoids rather than myeloids

        Pathway & Disease-focused RT2 Profiler PCR Array including CLEC6A: 
              Antifungal Response in human mouse rat

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    In Situ
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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of human and mouse.

    Orthologs for CLEC6A gene from Selected species (see all 4)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Clec4n1 , 5 C-type lectin domain family 4, member n1, 5 76.81(n)1
    69.57(a)1
      6 (58.30 cM)5
    566201  NM_020001.21  NP_064385.11 
     1232298435 


    ENSEMBL Gene Tree for CLEC6A (if available)
    TreeFam Gene Tree for CLEC6A (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for CLEC6A gene
    CD2072  CLEC17A2  CLEC4E2  ASGR22  CLEC4M2  CLEC4F2  CD2092  CLEC4A2  
    FCER22  CLEC10A2  ASGR12  CLEC4C2  CLEC4D2  CLEC4G2  
    9 SIMAP similar genes for CLEC6A using alignment to 1 protein entry:     CLC6A_HUMAN:
    CLEC4C    CLEC4D    CLEC4A    CLEC4M    COLEC12    ASGR2
    CD209    CLEC10A    CLEC4E

    CLEC6A for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for CLEC6A (see all 615)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 12 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs46161191,2
    C,F,A--8486349(+) ttcttT/Cttgcc 1 -- us2k1 trp312Minor allele frequency- C:0.23NA WA CSA EA 376
    rs1472023121,2
    --8486375(+) AATTTA/GCAAAG 1 -- us2k10--------
    rs42961041,2
    C,F,A,H--8486380(+) ACAAAA/GACAAA 1 -- us2k1 tfbs313Minor allele frequency- G:0.17NS EA NA WA 636
    rs43874291,2
    C,F,A--8486396(+) TCCTGC/TCTTCC 1 -- us2k1 trp311Minor allele frequency- T:0.22NA WA CSA EA 373
    rs1404872031,2
    --8486518(+) GAATCA/GTGAAG 1 -- us2k10--------
    rs44203481,2
    C,F,A,H--8486636(+) CACTTC/GTAGGT 1 -- us2k112Minor allele frequency- G:0.33NA WA CSA 257
    rs44203491,2
    C,F,A,H--8486639(+) TTGTAT/GGTTGC 1 -- us2k111Minor allele frequency- G:0.33NA WA CSA 255
    rs1842639161,2
    --8486660(+) GGTCTA/GGAGAG 1 -- us2k10--------
    rs44203501,2
    C,F,A,H--8486665(+) AGAGAA/GCAAAG 1 -- us2k114Minor allele frequency- G:0.24NA WA CSA EA 493
    rs1164813381,2
    F--8486727(+) CCATCC/ACAAAT 1 -- us2k11Minor allele frequency- A:0.04WA 118

    HapMap Linkage Disequilibrium report for CLEC6A (8608522 - 8630926 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 10 variations for CLEC6A:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2178781CNV Deletion18987734
    esv2587098CNV Deletion19546169
    esv2745506CNV Deletion23290073
    esv1064509CNV Deletion17803354
    nsv518125CNV Loss19592680
    esv6604CNV Loss19470904
    nsv518772CNV Gain19592680
    nsv428270CNV Gain18775914
    dgv461e1CNV Complex17122850
    dgv455e1CNV Complex17122850

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing CLEC6A
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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 613579    OMIM disorders: --

    5 diseases for CLEC6A:    About MalaCards
    superficial mycosis    job's syndrome    chronic mucocutaneous candidiasis    candidiasis
    tonsillitis

    1 disease from the University of Copenhagen DISEASES database for CLEC6A:
    Job's syndrome

    CLEC6A for disorders           About GeneDecksing


    Export disorders for CLEC6A gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for CLEC6A gene, integrated from 10 sources (see all 16):
    (articles sorted by number of sources associating them with CLEC6A)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Identification and expression profiling of a human C-type lectin, structurally homologous to mouse dectin-2. (PubMed id 15810886)1, 2, 9 Gavino A.C.... Cruz P.D. Jr. (Exp. Dermatol. 2005)
    2. Identification of lectin-like receptors expressed by antigen presenting cells and neutrophils and their mapping to a novel gene complex. (PubMed id 15368084)1, 2, 9 Flornes L.M....Fossum S. (Immunogenetics 2004)
    3. Molecular cloning of human dectin-2. (PubMed id 15175046)1, 2, 9 Kanazawa N.... Miyachi Y. (J. Invest. Dermatol. 2004)
    4. Selective C-Rel activation via Malt1 controls anti-fungal T(H)-17 immunity by dectin-1 and dectin-2. (PubMed id 21283787)1 Gringhuis S.I....Geijtenbeek T.B. (PLoS Pathog. 2011)
    5. The finished DNA sequence of human chromosome 12. (PubMed id 16541075)2 Scherer S.E.... Gibbs R.A. (Nature 2006)
    6. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    7. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
    8. Identification and gene expression of bovine C-type lectin dectin-2. (PubMed id 16213030)9 Bonkobara M....Ariizumi K. (Vet. Immunol. Immunopathol. 2006)
    9. The Dectin-2 family of C-type lectins in immunity and homeostasis. (PubMed id 19665392)9 Graham L.M. and Brown G.D. (Cytokine 2009)
    10. Induction of CD8+ T cell responses through targeting of antigen to Dectin-2. (PubMed id 16781694)9 Carter R.W....Tough D.F. (Cell. Immunol. 2006)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 93978 HGNC: 14556 Ensembl:ENSG00000205846 euGenes: HUgn93978 ECgene: CLEC6A
    H-InvDB: CLEC6A

    (According to HUGE)
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    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

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    NameDescription
    PharmGKB entry for CLEC6A Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for CLEC6A gene:
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    GeneCards and IP:
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