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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

CLEC4D Gene

protein-coding   GIFtS: 45
GCID: GC12P008666

C-type lectin domain family 4, member D

(Previous names: C-type (calcium dependent, carbohydrate-recognition domain)...)
(Previous symbol: CLECSF8)
 Explore 7 diseases affiliated with
CLEC4D via our new
 Human Malady Compendium 
Biological research products
for CLEC4D
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
C-Type Lectin Domain Family 4, Member D1 2     CLEC62 5
CLECSF81 2 3 5     Mpcl1
C-Type (Calcium Dependent, Carbohydrate-Recognition Domain) Lectin, Superfamily
Member 81 2
     MPCL2
CLEC-62 3     C-Type Lectin Domain Family 4 Member D2
MCL2 3     C-Type Lectin Receptor2
C-Type Lectin Superfamily Member 82 3     Macrophage C-Type Lectin2
C-Type Lectin-Like Receptor 62 3     

External Ids:    HGNC: 145541   Entrez Gene: 3383392   Ensembl: ENSG000001665277   OMIM: 6099645   UniProtKB: Q8WXI83   

Export aliases for CLEC4D gene to outside databases

Previous GC identifers: GC12P008559 GC12P008448


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for CLEC4D:
This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this
family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling,
glycoprotein turnover, and roles in inflammation and immune response. This gene is closely linked to other CTL/CTLD
superfamily members on chromosome 12p13 in the natural killer gene complex region. (provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: CLC4D_HUMAN, Q8WXI8
Function: Functions as an endocytic receptor. May be involved in antigen uptake at the site of infection, either for
clearance of the antigen, or for processing and further presentation to T cells




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000012.11  NC_018923.1  NT_009714.17  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the CLEC4D gene promoter:
         STAT5B   GR   Nkx3-1 v4   FOXF2   GR-beta   C/EBPalpha   HEN1   FAC1   Nkx3-1 v3   GR-alpha   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCLEC4D promoter sequence
   Search SABiosciences Chromatin IP Primers for CLEC4D

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CLEC4D


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12p13.31   Ensembl cytogenetic band:  12p13.31   HGNC cytogenetic band: 12p13.31

CLEC4D Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CLEC4D gene location

GeneLoc information about chromosome 12         GeneLoc Exon Structure

GeneLoc location for GC12P008666:  view genomic region     (about GC identifiers)

Start:
8,662,071 bp from pter      End:
8,674,962 bp from pter
Size:
12,892 bases      Orientation:
plus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: CLC4D_HUMAN, Q8WXI8 (See protein sequence)
Recommended Name: C-type lectin domain family 4 member D  
Size: 215 amino acids; 24704 Da
Subcellular location: Membrane; Single-pass type II membrane protein (Probable)
1 PDB 3D structure from and Proteopedia for CLEC4D:
2LS8 (3D)    
Secondary accessions: Q8N5J5

Explore the universe of human proteins at neXtProt for CLEC4D: NX_Q8WXI8

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q8WXI8

  • CLEC4D Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_525126.2  
    ENSEMBL proteins: 
     ENSP00000371496   ENSP00000299665  

    Human Recombinant Protein Products: 
    Browse Purified and Recombinant Proteins at EMD Millipore
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    OriGene Protein Over-expression Lysate: CLEC4D
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    Novus Biologicals CLEC4D Protein
    Novus Biologicals CLEC4D Lysates
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for CLEC4D

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016021integral to membrane IEA--


    CLEC4D for ontologies           About GeneDecksing



    CLEC4D Antibody Products: 
    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
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    Search for Antibodies for CLEC4D at Abcam  
    Uscn Antibodies for CLEC4D
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    Uscn ELISAs and CLIAs for CLEC4D


    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    CLEC4D for domains           About GeneDecksing

    3 InterPro domains/families:
     IPR016187 C-type_lectin_fold
     IPR016186 C-type_lectin-like
     IPR001304 C-type_lectin

    Graphical View of Domain Structure for InterPro Entry Q8WXI8

    ProtoNet protein and cluster: Q8WXI8

    1 Blocks protein family: IPB002353 Type II antifreeze protein signature

    UniProtKB/Swiss-Prot: CLC4D_HUMAN, Q8WXI8
    Similarity: Contains 1 C-type lectin domain


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: CLC4D_HUMAN, Q8WXI8
    Function: Functions as an endocytic receptor. May be involved in antigen uptake at the site of infection, either for
    clearance of the antigen, or for processing and further presentation to T cells
    Induction: By autocrine inflammatory stimuli

    miRNA
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    OriGene 3'-UTR Clone: CLEC4D
    Browse MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat CLEC4D
    8/15 QIAGEN miScript miRNA Assays for microRNAs that regulate CLEC4D (see all 15):
    hsa-miR-21* hsa-miR-548j hsa-miR-548w hsa-miR-559 hsa-miR-548i hsa-miR-548h hsa-miR-449c* hsa-miR-548c-5p
    SwitchGear 3'UTR luciferase reporter plasmidCLEC4D 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CLEC4D (see all 7)
    OriGene shRNA RFP: CLEC4D
    OriGene siRNA: CLEC4D
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CLEC4D

    Gene Editing
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    DNA2.0 Custom Protein Engineering Service for CLEC4D

    Clone
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    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CLEC4D (see all 4)
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    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
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    Sino Biological Human cDNA Clone for CLEC4D
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CLEC4D
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CLEC4D 

    Cell Line
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    GenScript Custom overexpressing Cell Line Services for CLEC4D
    Search LifeMap BioReagents cell lines for CLEC4D

    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CLEC4D

    Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0030246carbohydrate binding IEA--


    CLEC4D for ontologies           About GeneDecksing


    Animal Models:
         Mouse knock-outs for CLEC4D: Clec4dtm1Psob Clec4dtm1.1Cfg
         1 MGI mutant phenotype (inferred from 2 alleles(MGI details for Clec4d):
     no phenotypic analysis 

    CLEC4D for phenotypes           About GeneDecksing


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CLEC4D

    Gene Ontology (GO): 1 biological process term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0045087innate immune response IEA--


    CLEC4D for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    CLEC4D for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for CLEC4D
    4 Novoseek chemical compound relationships for CLEC4D gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    mannose 76.8 8 12960229 (1), 17467811 (1), 18160296 (1), 18811944 (1) (see all 8)
    polysaccharide 45.1 7 18679407 (1), 19764413 (1), 19748975 (1), 18981244 (1) (see all 5)
    carbohydrates 35.7 1 19353560 (1)
    tyrosine 0.059 4 18631453 (1), 20193029 (1), 19422460 (1)

    Search CenterWatch for drugs/clinical trials and news about CLEC4D / CLC4D 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for CLEC4D gene: 
    NM_080387.4  

    Unigene Cluster for CLEC4D:

    C-type lectin domain family 4, member D
    Hs.351811  [show with all ESTs]
    Unigene Representative Sequence: NM_080387
    2 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000382064 ENST00000299665(uc001qun.3)

    miRNA
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    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat CLEC4D
    8/15 QIAGEN miScript miRNA Assays for microRNAs that regulate CLEC4D (see all 15):
    hsa-miR-21* hsa-miR-548j hsa-miR-548w hsa-miR-559 hsa-miR-548i hsa-miR-548h hsa-miR-449c* hsa-miR-548c-5p
    SwitchGear 3'UTR luciferase reporter plasmidCLEC4D 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CLEC4D (see all 7)
    OriGene shRNA RFP: CLEC4D
    OriGene siRNA: CLEC4D
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CLEC4D
    Clone
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    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CLEC4D (see all 4)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CLEC4D
    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector: CLEC4D (NM_080387)
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CLEC4D 
    Primer
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    OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CLEC4D
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CLEC4D
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CLEC4D

    Additional cDNA sequence: 

    AF411850.1 AK314071.1 AY115592.1 AY297446.1 AY486482.1 AY486483.1 BC032313.1 

    1 DOTS entry:

    DT.75164002 

    12 AceView cDNA sequences:

    BC032313 NM_080387 AY115592 CA412024 AY297446 BI909298 AF411850 BI910606 
    AW074559 BM561886 AJ712390 BF902179 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    CLEC4D expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: AAACATTAAT

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image
    See CLEC4D Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for CLEC4D

    SOURCE GeneReport for Unigene cluster: Hs.351811

    UniProtKB/Swiss-Prot: CLC4D_HUMAN, Q8WXI8
    Tissue specificity: Expressed weakly in peripheral blood leukocytes, bone marrow and spleen. Expression is confined
    mostly in monocytes and macrophage and seems to be up-regulated by IL-6, IL-10, TNF-alpha and IFN-gamma

        SABiosciences Custom PCR Arrays for CLEC4D
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CLEC4D

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for CLEC4D gene from 1/8 species (see all 8)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    zebrafish
    (Danio rerio)
    Actinopterygii CABZ01036814.16
    BX682234.36
    (see all 41)
    --
    9(a)
    7(a)
    (see all 41)
    many ↔ many
    many ↔ many
    (see all 41)
    1(56517096-56534610)
    10(7530024-7534761)


    ENSEMBL Gene Tree for CLEC4D (if available)
    TreeFam Gene Tree for CLEC4D (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for CLEC4D gene
    CD2072  CLEC4E2  ASGR22  CLEC4M2  CLEC4F2  CD2092  CLEC10A2  FCER22  
    CLEC4A2  ASGR12  CLEC6A2  CLEC4C2  CLEC4G2  
    13 SIMAP similar genes for CLEC4D using alignment to 2 protein entries:     CLC4D_HUMAN (see all proteins):
    CLEC6A    CLEC4A    CLEC4E    CLEC4C    DKFZp761L191    CD209
    CLEC4M    ACAN    ASGR2    FCER2    HBXBP    VCAN
    DKFZp686K06110

    CLEC4D for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/229 NCBI SNPs in CLEC4D are shown (see all 229    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 12 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1149613601,2
    F,--8664161(+) CTGCCT/GCCTAC 1 -- us2k11Minor allele frequency- G:0.06WA 118
    rs1931600721,2
    --8664257(+) TGAGAC/GTGGCC 1 -- us2k10--------
    rs1476814001,2
    --8664270(+) AGATAC/TAGGAA 1 -- us2k10--------
    rs1828080891,2
    --8664313(+) GGGGGA/CAAAGA 1 -- us2k10--------
    rs71359601,2
    C,F,A,H,--8664351(+) AGCACG/TACAAA 1 -- us2k123Minor allele frequency- T:0.33NS EA NA WA CSA 2348
    rs1161815061,2
    F,--8664515(+) AATCCT/CGGAGG 1 -- us2k11Minor allele frequency- C:0.04WA 118
    rs1424327561,2
    --8664563(+) CTCTGC/GGAAGG 1 -- us2k10--------
    rs284855671,2
    C,F,--8664719(+) TGGGCT/CACAGG 1 -- us2k18Minor allele frequency- C:0.34WA NA CSA EA 367
    rs1130898801,2
    --8664739(+) CAGCAG/TCCTAC 1 -- us2k11Minor allele frequency- T:0.50CSA 2
    rs1478730921,2
    --8664740(+) AGCATC/TCTACT 1 -- us2k10--------

    HapMap Linkage Disequilibrium report for CLEC4D (8662071 - 8674962 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for CLEC4D: --

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CLEC4D
    DNA2.0 Custom Variant and Variant Library Synthesis for CLEC4D

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Novoseek, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    CLEC4D for disorders           About GeneDecksing

    OMIM gene information: 609964    OMIM disorders: --

    7 diseases for CLEC4D:    About MalaCards
    systemic lupus erythematosus    lupus erythematosus    behcet's disease    acne
    influenza    immunodeficiency    asthma

    4 Novoseek disease relationships for CLEC4D gene    About this table

    Disease   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    immunodeficiency 24.1 2 12960236 (1), 18593570 (1)
    hiv infections 18.5 2 19363450 (1), 20395432 (1)
    tumors 0 1 15024991 (1)
    cancer 0 1 11774590 (1)


    Export disorders for CLEC4D gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for CLEC4D gene, integrated from 9 sources (see all 104):
    (articles sorted by number of sources associating them with CLEC4D)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The human C-type lectin CLECSF8 is a novel monocyte/macrophage endocytic receptor. (PubMed id 14971047)1, 2, 9 Arce I.... Fernandez-Ruiz E. (2004)
    2. Identification of lectin-like receptors expressed by antigen presenting cells and neutrophils and their mapping to a novel gene complex. (PubMed id 15368084)1, 2 Flornes L.M....Fossum S. (2004)
    3. The C-type lectin receptor CLECSF8 (CLEC4D) is express ed by myeloid cells and triggers cellular activation through Syk kinase. (PubMed id 22689578)1 Graham L.M....Brown G.D. (2012)
    4. Toward a confocal subcellular atlas of the human proteome. (PubMed id 18029348)1 Barbe L....Andersson-Svahn H. (2008)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)2 Gerhard D.S....Malek J. (2004)
    6. Evolutionary analysis reveals collective properties and specificity in the C-type lectin and lectin-like domain superfamily. (PubMed id 12945048)1 Ebner S....Ben-Tal N. (2003)
    7. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
    8. C-type lectin-like domains. (PubMed id 10508765)1 Drickamer K. (1999)
    9. Abundant expression of HIV target cells and C-type le ctin receptors in the foreskin tissue of young Kenyan men. (PubMed id 20395432)9 Hirbod T....Broliden K. (2010)
    10. Functional interaction of common allergens and a C-ty pe lectin receptor, dendritic cell-specific ICAM3-grabbing non-integrin (DC-SIG N), on human dendritic cells. (PubMed id 20080962)9 Hsu S.C....Huang S.K. (2010)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Disorders
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 338339 HGNC: 14554 AceView: CLECSF8 Ensembl:ENSG00000166527 euGenes: HUgn338339
    ECgene: CLEC4D H-InvDB: CLEC4D

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for CLEC4D Pharmacogenomics, SNPs, Pathways
    Functional Glycomics Gateway - Glycan Bindinghttp://www.functionalglycomics.org/glycomics/GBPServlet?&operationType=view&cbpId=cbp_hum_Ctlect_365

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for CLEC4D gene:
    Search GeneIP for patents involving CLEC4D

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
    In Situ Hybridization Assays from
    Advanced Cell Diagnostics
    About This Section

     
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    GeneCards Homepage - Last full update: 19 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

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