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CLEC4C Gene

protein-coding   GIFtS: 51
GCID: GC12M007882

C-Type Lectin Domain Family 4, Member C

(Previous names: C-type (calcium dependent, carbohydrate-recognition domain)...)
(Previous symbols: CLECSF11, CLECSF7)
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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
C-Type Lectin Domain Family 4, Member C1 2     C-Type Lectin Superfamily Member 72 3
CLECSF111 2 3 5     CD3032
CLECSF71 2 3     PRO341502
BDCA22 3 5     Blood Dendritic Cell Antigen 2 Protein2
DLEC2 3 5     C-Type (Calcium Dependent, Carbohydrate-Recognition Domain) Lectin,
Superfamily Member 112
C-Type (Calcium Dependent, Carbohydrate-Recognition Domain) Lectin,
Superfamily Member 71 2
     C-Type Lectin Domain Family 4 Member C2
Dendritic Lectin2 3     Dendritic Cell Lectin B2
BDCA-22 3     Blood Dendritic Cell Antigen 23
HECL2 3     CD303 Antigen3

External Ids:    HGNC: 132581   Entrez Gene: 1704822   Ensembl: ENSG000001981787   OMIM: 6066775   UniProtKB: Q8WTT03   

Export aliases for CLEC4C gene to outside databases

Previous GC identifers: GC12M007776 GC12M007695


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for CLEC4C Gene:
This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this
family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling,
glycoprotein turnover, and roles in inflammation and immune response. The encoded type 2 transmembrane protein
may play a role in dendritic cell function. Two transcript variants encoding distinct isoforms have been
identified for this gene. (provided by RefSeq, Jul 2008)

GeneCards Summary for CLEC4C Gene:
CLEC4C (C-type lectin domain family 4, member C) is a protein-coding gene. GO annotations related to this gene include carbohydrate binding. An important paralog of this gene is CD207.

UniProtKB/Swiss-Prot: CLC4C_HUMAN, Q8WTT0
Function: Involved in antigen-capturing. Target ligand into antigen processing and peptide-loading compartments
for presentation to T-cells. May mediate potent inhibition of induction of IFN-alpha/beta expression in
plasmacytoid dendritic cells. May act as a signaling receptor that activates protein-tyrosine kinases and
mobilizes intracellular calcium. Does not seem to bind mannose




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence at NCBI GenBank:
NC_000012.11  NT_009714.18  NC_018923.2  
Regulatory elements:
   Regulatory transcription factor binding sites in the CLEC4C gene promoter:
         AREB6   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): CLEC4C promoter sequence
   Search Chromatin IP Primers for CLEC4C

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat CLEC4C


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 12p13.2-p12.3   Ensembl cytogenetic band:  12p13.31   HGNC cytogenetic band: 12p13.2-p12.3

CLEC4C Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CLEC4C gene location

GeneLoc information about chromosome 12         GeneLoc Exon Structure

GeneLoc location for GC12M007882:  view genomic region     (about GC identifiers)

Start:
7,882,011 bp from pter      End:
7,904,201 bp from pter
Size:
22,191 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, Cloud-Clone Corp., and/or eBioscience,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, Cloud-Clone Corp., and/or eBioscience, Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: CLC4C_HUMAN, Q8WTT0 (See protein sequence)
Recommended Name: C-type lectin domain family 4 member C  
Size: 213 amino acids; 25038 Da
3 PDB 3D structures from and Proteopedia for CLEC4C:
3WBP (3D)        3WBQ (3D)        3WBR (3D)    
Secondary accessions: D3DUU3 Q3T1C3 Q6UXS8 Q8WXX8
Alternative splicing: 2 isoforms:  Q8WTT0-1   Q8WTT0-2   

Explore the universe of human proteins at neXtProt for CLEC4C: NX_Q8WTT0

Explore proteomics data for CLEC4C at MOPED

Post-translational modifications: 

  • Glycosylation2 at Asn110, Asn137, Asn164

  • See CLEC4C Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins (2 alternative transcripts): 
    NP_569708.1  NP_987099.1  

    ENSEMBL proteins: 
     ENSP00000440428   ENSP00000346648   ENSP00000353500   ENSP00000438649   ENSP00000442457  
     ENSP00000445338  

    CLEC4C Human Recombinant Protein Products:

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    Cloud-Clone Corp. Proteins for CLEC4C

     
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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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    HGNC Gene Families:
    CD: CD molecules
    CLEC: C-type lectin domain containing

    4 InterPro protein domains:
     IPR016187 C-type_lectin_fold
     IPR018378 C-type_lectin_CS
     IPR016186 C-type_lectin-like
     IPR001304 C-type_lectin

    Graphical View of Domain Structure for InterPro Entry Q8WTT0

    ProtoNet protein and cluster: Q8WTT0

    1 Blocks protein domain: IPB002353 Type II antifreeze protein signature

    UniProtKB/Swiss-Prot: CLC4C_HUMAN, Q8WTT0
    Similarity: Contains 1 C-type lectin domain


    Find genes that share domains with CLEC4C           About GenesLikeMe


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, Vector BioLabs and/or Addgene, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Flow cytometry from eBioscience, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Molecular Function:

         UniProtKB/Swiss-Prot Summary: CLC4C_HUMAN, Q8WTT0
    Function: Involved in antigen-capturing. Target ligand into antigen processing and peptide-loading compartments
    for presentation to T-cells. May mediate potent inhibition of induction of IFN-alpha/beta expression in
    plasmacytoid dendritic cells. May act as a signaling receptor that activates protein-tyrosine kinases and
    mobilizes intracellular calcium. Does not seem to bind mannose

         Gene Ontology (GO): 1 molecular function term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0030246carbohydrate binding IEA--
         
    Find genes that share ontologies with CLEC4C           About GenesLikeMe


    Phenotypes:
         1 GenomeRNAi human phenotype for CLEC4C:
     Decreased cilium length after  

    Animal Models:
       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for CLEC4C
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    Browse Sino Biological Human cDNA Clones
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    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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    Subcellular locations from UniProtKB/Swiss-Prot
    CLC4C_HUMAN, Q8WTT0: Membrane; Single-pass type II membrane protein (Probable)
    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    plasma membrane3
    extracellular2
    cytosol1
    golgi apparatus1
    nucleus1

    Gene Ontology (GO): 1 cellular component term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016021integral component of membrane IEA--

    Find genes that share ontologies with CLEC4C           About GenesLikeMe


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    SuperPaths for CLEC4C About    
    See pathways by source

    SuperPathContained pathways About
    1NOD-like Receptor Signaling Pathways
    Pathogen or Damage-activated C-Type Lectin Receptor Signaling Pathways0.31

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways

    1 R&D Systems Pathway for CLEC4C
        Pathogen or Damage-activated C-Type Lectin Receptor Signaling Pathways



        Pathway & Disease-focused RT2 Profiler PCR Array including CLEC4C: 
              Antigen Presenting Cells in human mouse rat

    Interactions:

        Search GeneGlobe Interaction Network for CLEC4C

    STRING Interaction Network Preview (showing 2 interactants - click image to see more details)

    2 Interacting proteins for CLEC4C (Q8WTT03 ENSP000003535004) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    NEK2P519553, ENSP000003559664I2D: score=1 STRING: ENSP00000355966
    FCER1GENSP000002899024STRING: ENSP00000289902
    About this table

    Gene Ontology (GO): 1 biological process term:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0045087innate immune response IEA--

    Find genes that share ontologies with CLEC4C           About GenesLikeMe



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for CLEC4C (CLC4C)

    1 HMDB Compound for CLEC4C    About this table
    CompoundSynonyms CAS #PubMed Ids
    CalciumCa (see all 2)7440-70-2--



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, and/or Addgene, Primers from OriGene, and/or QIAGEN, Flow cytometry from eBioscience )
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    REFSEQ mRNAs for CLEC4C gene (2 alternative transcripts): 
    NM_130441.2  NM_203503.1  

    Unigene Cluster for CLEC4C:

    C-type lectin domain family 4, member C
    Hs.351812  [show with all ESTs]
    Unigene Representative Sequence: AK122596
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000542353(uc001qth.1) ENST00000354629 ENST00000360345(uc001qtg.1)
    ENST00000537530 ENST00000543765 ENST00000540085(uc001qti.1)
    miRNA
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    Additional mRNA sequence: 

    AF293615.1 AF325459.1 AF325460.1 AK122596.1 AY358223.1 BC074967.2 BC074968.2 BC102015.1 
    BC102016.1 BC102017.1 BC114338.1 

    4 DOTS entries:

    DT.95155588  DT.101978660  DT.75134426  DT.100742135 

    14 AceView cDNA sequences:

    BC074967 NM_203503 BC074968 NM_130441 AF293615 AI183967 AF325460 BX109126 
    AY358223 AF325459 AK122596 CD707910 AA868502 BQ333717 

    GeneLoc Exon Structure

    3 Alternative Splicing Database (ASD) splice patterns (SP) for CLEC4C    About this scheme

    ExUns: 1 ^ 2a · 2b · 2c ^ 3 ^ 4 ^ 5 ^ 6 ^ 7
    SP1:        -                                             
    SP2:                                                      
    SP3:                          -                           


    ECgene alternative splicing isoforms for CLEC4C

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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    CLEC4C expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: --
    CLEC4C Expression
    About this image

    CLEC4C Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    CLEC4C Protein Expression

    SOURCE GeneReport for Unigene cluster: Hs.351812

    UniProtKB/Swiss-Prot: CLC4C_HUMAN, Q8WTT0
    Tissue specificity: Expressed in plasmacytoid dendritic cells (PDCs). Constitutively expressed in immature
    monocyte-derived dendritic cells (iMDDC) and is significantly down-regulated upon maturation with LPS but not
    with TNF-alpha

        Pathway & Disease-focused RT2 Profiler PCR Array including CLEC4C: 
              Antigen Presenting Cells in human mouse rat

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    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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    This gene was present in the common ancestor of human and mouse.

    Orthologs for CLEC4C gene from Selected species (see all 3)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Clec4b11 C-type lectin domain family 4, member b1 63.68(n)
    54.23(a)
      69810  NM_001190310.1  NP_001177239.1 


    ENSEMBL Gene Tree for CLEC4C (if available)
    TreeFam Gene Tree for CLEC4C (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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    Paralogs for CLEC4C gene
    CD2072  CLEC17A2  CLEC4E2  ASGR22  CLEC4M2  CLEC4F2  CD2092  CLEC4A2  
    FCER22  CLEC10A2  CLEC6A2  ASGR12  CLEC4D2  CLEC4G2  
    Selected SIMAP similar genes for CLEC4C using alignment to 3 protein entries:     CLC4C_HUMAN (see all proteins) (see all similar genes):
    CLEC4A    CLEC6A    FCER2    CLEC10A    CLEC2D    CD209
    CLEC5A    ASGR1    CLEC4D    KLRD1    KLRC1    NCAN
    CLEC4E    CLEC2B    KLRC2    CLEC4M    CLEC2L    VCAN

    Find genes that share paralogs with CLEC4C           About GenesLikeMe



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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    Selected SNPs for CLEC4C (see all 691)    About this table                                 

    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 12 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1509762851,2
    --7717765(+) TCTCTC/TGGCGA 2 -- us2k10--------
    rs1408382341,2
    --7717777(+) CTTGTA/GGTCTT 2 -- us2k10--------
    rs1502085671,2
    --7717783(+) GTCTTA/GCTAGC 2 -- us2k10--------
    rs749033221,2
    C,F--7717787(+) TGCTAG/CCTTCA 2 -- us2k12Minor allele frequency- C:0.09NA EA 240
    rs110556021,2
    C,F,A--7717797(+) aggagT/Ggaagc 2 -- us2k110Minor allele frequency- G:0.36NA CSA WA EA 369
    rs1468168501,2
    --7717807(+) CTACAA/GACTTC 2 -- us2k10--------
    rs73160351,2
    C,A,H--7717812(+) gacttT/Ccgcgg 2 -- us2k112Minor allele frequency- C:0.06NA WA CSA EA 255
    rs1882803761,2
    --7717816(+) TCCGCA/GGTATC 2 -- us2k10--------
    rs73160361,2
    C,A,H--7717821(+) ggtatT/Cacagc 2 -- us2k112Minor allele frequency- C:0.05NA WA CSA EA 255
    rs1922166811,2
    --7717839(+) AGAACC/TGTGGA 2 -- us2k10--------

    HapMap Linkage Disequilibrium report for CLEC4C (7882011 - 7904201 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 9 variations for CLEC4C:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2662383CNV Deletion23128226
    esv2422393CNV Duplication17116639
    dgv6e196CNV Duplication17116639
    dgv5e196CNV Duplication17116639
    dgv1354n71CNV Gain21882294
    dgv57e55CNV Gain17911159
    nsv428270CNV Gain18775914
    dgv454e1CNV Complex17122850
    dgv455e1CNV Complex17122850

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing CLEC4C
    DNA2.0 Custom Variant and Variant Library Synthesis for CLEC4C

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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    OMIM gene information: 606677    OMIM disorders: --


    Find genes that share disorders with CLEC4C           About GenesLikeMe

    Genetic Association Database (GAD): CLEC4C
    Human Genome Epidemiology (HuGE) Navigator: CLEC4C (1 document)

    Export disorders for CLEC4C gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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    PubMed articles for CLEC4C gene, integrated from 10 sources (see all 25):
    (articles sorted by number of sources associating them with CLEC4C)
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    1. Identification and characterization of the gene for a novel C-type lectin (CLECSF7) that maps near the natural killer gene complex on human chromosome 12. (PubMed id 11031109)1, 2, 3, 9 Fernandes M.J.... Calabretta B. (Genomics 2000)
    2. Molecular and genomic characterization of human DLEC, a novel member of the C-type lectin receptor gene family preferentially expressed on monocyte-derived dendritic cells. (PubMed id 11536172)1, 2, 3 Arce I.... Fernandez-Ruiz E. (Eur. J. Immunol. 2001)
    3. Dengue hemorrhagic fever is associated with polymorphisms in JAK1. (PubMed id 20588308)1, 4 Silva L.K....Teixeira M.G. (Eur. J. Hum. Genet. 2010)
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    5. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2 Clark H.F.... Gray A.M. (Genome Res. 2003)
    6. BDCA-2, a novel plasmacytoid dendritic cell-specific type II C-type lectin, mediates antigen capture and is a potent inhibitor of interferon alpha/beta induction. (PubMed id 11748283)1, 2 Dzionek A.... Schmitz J. (J. Exp. Med. 2001)
    7. BDCA2/Fc epsilon RI gamma complex signals through a novel BCR-like pathway in human plasmacytoid dendritic cells. (PubMed id 17850179)1, 9 Cao W....Liu Y.J. (PLoS Biol. 2007)
    8. HCV glycoprotein E2 is a novel BDCA-2 ligand and acts as an inhibitor of IFN production by plasmacytoid dendritic cells. (PubMed id 23053572)1 Florentin J....Stranska R. (Blood 2012)
    9. Human C-type lectin domain family 4, member C (CLEC4C/BDCA-2/CD303) is a receptor for asialo-galactosyl-oligosaccharides. (PubMed id 21880719)1 Riboldi E....Sozzani S. (J. Biol. Chem. 2011)
    10. Immunohistochemical characterisation of dendritic cells in human atherosclerotic lesions: possible pitfalls. (PubMed id 21436634)1 Van VrAc E.A....Bult H. (Pathology 2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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    Entrez Gene: 170482 HGNC: 13258 AceView: CLECSF7 Ensembl:ENSG00000198178 euGenes: HUgn170482
    ECgene: CLEC4C H-InvDB: CLEC4C

    (According to HUGE)
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      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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    NameDescription
    PharmGKB entry for CLEC4C Pharmacogenomics, SNPs, Pathways
    Functional Glycomics Gateway - Glycan Bindinghttp://www.functionalglycomics.org/glycomics/GBPServlet?&operationType=view&cbpId=cbp_hum_Ctlect_00133

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
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    Patent Information for CLEC4C gene:
    Search GeneIP for patents involving CLEC4C

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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