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Aliases for CLEC2L Gene

Aliases for CLEC2L Gene

  • C-Type Lectin Domain Family 2, Member L 2 3

External Ids for CLEC2L Gene

Previous GeneCards Identifiers for CLEC2L Gene

  • GC07P138677
  • GC07P138872
  • GC07P139208
  • GC07P133519

Summaries for CLEC2L Gene

GeneCards Summary for CLEC2L Gene

CLEC2L (C-Type Lectin Domain Family 2, Member L) is a Protein Coding gene. GO annotations related to this gene include carbohydrate binding. An important paralog of this gene is CLEC2A.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CLEC2L Gene

Genomics for CLEC2L Gene

Regulatory Elements for CLEC2L Gene

Epigenetics Products

  • DNA Methylation CpG Assay Predesigned for Pyrosequencing in human,mouse,rat

Genomic Location for CLEC2L Gene

139,523,856 bp from pter
139,544,985 bp from pter
21,130 bases
Plus strand

Genomic View for CLEC2L Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for CLEC2L Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CLEC2L Gene

Proteins for CLEC2L Gene

  • Protein details for CLEC2L Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    C-type lectin domain family 2 member L
    Protein Accession:
    Secondary Accessions:

    Protein attributes for CLEC2L Gene

    214 amino acids
    Molecular mass:
    23927 Da
    Quaternary structure:
    No Data Available

neXtProt entry for CLEC2L Gene

Proteomics data for CLEC2L Gene at MOPED

Post-translational modifications for CLEC2L Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for CLEC2L Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for CLEC2L Gene

Domains for CLEC2L Gene

Gene Families for CLEC2L Gene

Protein Domains for CLEC2L Gene

Suggested Antigen Peptide Sequences for CLEC2L Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Contains 1 C-type lectin domain.
  • Contains 1 C-type lectin domain.
genes like me logo Genes that share domains with CLEC2L: view

Function for CLEC2L Gene

Gene Ontology (GO) - Molecular Function for CLEC2L Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0030246 carbohydrate binding IEA --
genes like me logo Genes that share ontologies with CLEC2L: view

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for CLEC2L Gene

Localization for CLEC2L Gene

Subcellular locations from UniProtKB/Swiss-Prot for CLEC2L Gene

Membrane; Single-pass membrane protein.

Subcellular locations from

Jensen Localization Image for CLEC2L Gene COMPARTMENTS Subcellular localization image for CLEC2L gene
Compartment Confidence
cytosol 1
mitochondrion 1
nucleus 1
peroxisome 1

Gene Ontology (GO) - Cellular Components for CLEC2L Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with CLEC2L: view

Pathways for CLEC2L Gene

SuperPathways for CLEC2L Gene

No Data Available

Interacting Proteins for CLEC2L Gene

STRING Interaction Network Preview (showing 2 interactants - click image to see details)
Selected Interacting proteins: ENSP00000390661 P0C7M8-CLC2L_HUMAN for CLEC2L Gene via STRING I2D

Gene Ontology (GO) - Biological Process for CLEC2L Gene


No data available for Pathways by source for CLEC2L Gene

Transcripts for CLEC2L Gene

mRNA/cDNA for CLEC2L Gene

(1) REFSEQ mRNAs :
(1) Additional mRNA sequences :
(13) Selected AceView cDNA sequences:
(3) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for CLEC2L Gene

C-type lectin domain family 2, member L:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for CLEC2L Gene

No ASD Table

Relevant External Links for CLEC2L Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for CLEC2L Gene

mRNA expression in normal human tissues for CLEC2L Gene

mRNA differential expression in normal tissues according to GTEx for CLEC2L Gene

This gene is overexpressed in Brain - Cortex (8.3), Brain - Anterior cingulate cortex (BA24) (7.4), Brain - Frontal Cortex (BA9) (7.2), Brain - Cerebellum (4.3), and Brain - Hippocampus (4.2).

Protein differential expression in normal tissues for CLEC2L Gene

This gene is overexpressed in Frontal cortex (53.9) and Platelet (7.9).

Integrated Proteomics: protein expression from ProteomicsDB, PaxDb, and MOPED for CLEC2L Gene

SOURCE GeneReport for Unigene cluster for CLEC2L Gene Hs.57806

genes like me logo Genes that share expressions with CLEC2L: view

Expression partners for CLEC2L Gene

* - Elite partner

Primer Products

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery and mRNA Expression by UniProt/SwissProt for CLEC2L Gene

Orthologs for CLEC2L Gene

This gene was present in the common ancestor of chordates.

Orthologs for CLEC2L Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia LOC781590 35
  • 90.74 (n)
  • 96.67 (a)
  • 92 (a)
(Canis familiaris)
Mammalia CLEC2L 35
  • 82.72 (n)
  • 86.24 (a)
  • 89 (a)
(Mus musculus)
Mammalia Clec2l 35
  • 89.26 (n)
  • 96.11 (a)
Clec2l 16
Clec2l 36
  • 96 (a)
(Pan troglodytes)
Mammalia CLEC2L 35
  • 100 (n)
  • 100 (a)
  • 100 (a)
(Rattus norvegicus)
Mammalia Clec2l 35
  • 89.81 (n)
  • 96.11 (a)
(Monodelphis domestica)
Mammalia CLEC2L 36
  • 83 (a)
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 27 (a)
-- 36
  • 27 (a)
(Gallus gallus)
Aves -- 36
  • 24 (a)
Species with no ortholog for CLEC2L:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for CLEC2L Gene

Gene Tree for CLEC2L (if available)
Gene Tree for CLEC2L (if available)

Paralogs for CLEC2L Gene

Paralogs for CLEC2L Gene

(13) SIMAP similar genes for CLEC2L Gene using alignment to 2 proteins:

genes like me logo Genes that share paralogs with CLEC2L: view

Variants for CLEC2L Gene

Sequence variations from dbSNP and Humsavar for CLEC2L Gene

SNP ID Clin Chr 07 pos Sequence Context AA Info Type MAF
rs740529 -- 139,524,241(+) GGCGC(C/T)GGGAC intron-variant
rs1860151 -- 139,527,152(-) CCCCC(C/T)TGCAA intron-variant
rs2240641 -- 139,529,552(-) CTTGG(C/T)GGCAG intron-variant
rs2530724 -- 139,526,363(-) GACCC(A/G)TCTCT intron-variant
rs4081612 -- 139,534,511(-) GTAGA(C/T)CTTCT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for CLEC2L Gene

Variant ID Type Subtype PubMed ID
esv2735212 CNV Deletion 23290073
esv24293 CNV Gain 19812545

Relevant External Links for CLEC2L Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CLEC2L Gene

Disorders for CLEC2L Gene

Relevant External Links for CLEC2L

Genetic Association Database (GAD)

No disorders were found for CLEC2L Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships and Genatlas for CLEC2L Gene

Publications for CLEC2L Gene

  1. The sequence of the human genome. (PMID: 11181995) Venter J.C. … Zhu X. (Science 2001) 3
  2. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 3
  3. Large-scale mapping of human protein-protein interactions by mass spectrometry. (PMID: 17353931) Ewing R.M. … Figeys D. (Mol. Syst. Biol. 2007) 3
  4. A genome-wide association study of type 2 diabetes in Finns detects multiple susceptibility variants. (PMID: 17463248) Scott L.J. … Boehnke M. (Science 2007) 48
  5. The DNA sequence of human chromosome 7. (PMID: 12853948) Hillier L.W. … Wilson R.K. (Nature 2003) 4

Products for CLEC2L Gene

Sources for CLEC2L Gene

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