Aliases for CLEC2B Gene
External Ids for CLEC2B Gene
Previous HGNC Symbols for CLEC2B Gene
Previous GeneCards Identifiers for CLEC2B Gene
This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type 2 transmembrane protein may function as a cell activation antigen. An alternative splice variant has been described but its full-length sequence has not been determined. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region. [provided by RefSeq, Jul 2008]
GeneCards Summary for CLEC2B Gene
CLEC2B (C-Type Lectin Domain Family 2, Member B) is a Protein Coding gene. Diseases associated with CLEC2B include partial optic atrophy and lown-ganong-levine syndrome. Among its related pathways are Immune System and Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell. GO annotations related to this gene include carbohydrate binding. An important paralog of this gene is CLEC2A.