Aliases for CLEC1B Gene
External Ids for CLEC1B Gene
Previous GeneCards Identifiers for CLEC1B Gene
Natural killer (NK) cells express multiple calcium-dependent (C-type) lectin-like receptors, such as CD94 (KLRD1; MIM 602894) and NKG2D (KLRC4; MIM 602893), that interact with major histocompatibility complex class I molecules and either inhibit or activate cytotoxicity and cytokine secretion. CLEC2 is a C-type lectin-like receptor expressed in myeloid cells and NK cells (Colonna et al., 2000 [PubMed 10671229]).[supplied by OMIM, Jan 2011]
GeneCards Summary for CLEC1B Gene
CLEC1B (C-Type Lectin Domain Family 1 Member B) is a Protein Coding gene. Among its related pathways are G beta-gamma signalling through PI3Kgamma and Platelet activation, signaling and aggregation. GO annotations related to this gene include transmembrane signaling receptor activity and carbohydrate binding. An important paralog of this gene is CLEC7A.