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Aliases for CLEC19A Gene

Aliases for CLEC19A Gene

  • C-Type Lectin Domain Containing 19A 2 3
  • C-Type Lectin Domain Family 19 Member A 2 5
  • C-Type Lectin Domain Family 19, Member A 2

External Ids for CLEC19A Gene

Previous GeneCards Identifiers for CLEC19A Gene

  • GC00U926688

Summaries for CLEC19A Gene

GeneCards Summary for CLEC19A Gene

CLEC19A (C-Type Lectin Domain Containing 19A) is a Protein Coding gene. GO annotations related to this gene include carbohydrate binding.

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CLEC19A Gene

Genomics for CLEC19A Gene

Regulatory Elements for CLEC19A Gene

Enhancers for CLEC19A Gene
GeneHancer Identifier Enhancer Score Enhancer Sources Gene-Enhancer Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor Binding Sites within enhancer Gene Targets for Enhancer
GH16G019294 1.1 Ensembl ENCODE 0.4 +8.9 8901 1.3 PKNOX1 TBL1XR1 ZMYM3 MAX BMI1 CEBPG EBF1 ZBTB40 RELA ZFHX2 CLEC19A ENSG00000259871
GH16G019284 0.6 ENCODE 0.7 -1.3 -1262 0.4 ZNF664 JUND EED IKZF1 JUNB HNF4A ZIC2 TCF7L2 CLEC19A SYT17
GH16G019289 0.5 ENCODE 0.7 +4.4 4381 0.9 ZFHX2 ZMYM3 RBBP5 ZNF398 EGR2 CLEC19A ENSG00000259871
GH16G019209 1.5 FANTOM5 Ensembl ENCODE 0.2 -74.2 -74247 3.2 HDGF CBX3 BMI1 YBX1 RAD21 ZNF366 CBX5 ZNF143 ZNF207 RELB SYT17 COQ7 RNU4-46P SMG1 CLEC19A
GH16G019291 0.7 ENCODE 0.4 +5.8 5848 0.9 RFX1 MAX MAFG BACH1 CEBPB BMI1 ZNF121 RFX3 NFE2 FOXJ2 ENSG00000259925 CLEC19A ENSG00000259871
- Elite enhancer and/or Elite enhancer-gene association Download GeneHancer data dump

Enhancers around CLEC19A on UCSC Golden Path with GeneCards custom track

Genomic Location for CLEC19A Gene

19,285,739 bp from pter
19,324,537 bp from pter
38,799 bases
Plus strand

Genomic View for CLEC19A Gene

Genes around CLEC19A on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
CLEC19A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for CLEC19A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CLEC19A Gene

Proteins for CLEC19A Gene

  • Protein details for CLEC19A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    C-type lectin domain family 19 member A
    Protein Accession:
    Secondary Accessions:
    • Q0VF32

    Protein attributes for CLEC19A Gene

    136 amino acids
    Molecular mass:
    15448 Da
    Quaternary structure:
    No Data Available

neXtProt entry for CLEC19A Gene

Post-translational modifications for CLEC19A Gene

Other Protein References for CLEC19A Gene

No data available for DME Specific Peptides for CLEC19A Gene

Domains & Families for CLEC19A Gene

Gene Families for CLEC19A Gene

Protein Domains for CLEC19A Gene

Suggested Antigen Peptide Sequences for CLEC19A Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with CLEC19A: view

No data available for UniProtKB/Swiss-Prot for CLEC19A Gene

Function for CLEC19A Gene

Gene Ontology (GO) - Molecular Function for CLEC19A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0030246 carbohydrate binding IEA --
genes like me logo Genes that share ontologies with CLEC19A: view

Phenotypes for CLEC19A Gene

GenomeRNAi human phenotypes for CLEC19A:
genes like me logo Genes that share phenotypes with CLEC19A: view

Animal Model Products

CRISPR Products

Clone Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for CLEC19A Gene

Localization for CLEC19A Gene

Subcellular locations from UniProtKB/Swiss-Prot for CLEC19A Gene


Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for CLEC19A gene
Compartment Confidence
extracellular 3

Gene Ontology (GO) - Cellular Components for CLEC19A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005576 extracellular region IEA --
genes like me logo Genes that share ontologies with CLEC19A: view

Pathways & Interactions for CLEC19A Gene

SuperPathways for CLEC19A Gene

No Data Available

Interacting Proteins for CLEC19A Gene

Gene Ontology (GO) - Biological Process for CLEC19A Gene


No data available for Pathways by source and SIGNOR curated interactions for CLEC19A Gene

Drugs & Compounds for CLEC19A Gene

No Compound Related Data Available

Transcripts for CLEC19A Gene

mRNA/cDNA for CLEC19A Gene

(1) REFSEQ mRNAs :
(1) Additional mRNA sequences :
(5) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for CLEC19A Gene

C-type lectin domain family 19, member A:
Representative Sequences:

CRISPR Products

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for CLEC19A Gene

No ASD Table

Relevant External Links for CLEC19A Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for CLEC19A Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for CLEC19A Gene

Protein differential expression in normal tissues from HIPED for CLEC19A Gene

This gene is overexpressed in Adipocyte (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, PaxDb, and MOPED for CLEC19A Gene

Protein tissue co-expression partners for CLEC19A Gene

NURSA nuclear receptor signaling pathways regulating expression of CLEC19A Gene:


SOURCE GeneReport for Unigene cluster for CLEC19A Gene:

genes like me logo Genes that share expression patterns with CLEC19A: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for CLEC19A Gene

Orthologs for CLEC19A Gene

This gene was present in the common ancestor of animals.

Orthologs for CLEC19A Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia CLEC19A 34
  • 98.75 (n)
(Canis familiaris)
Mammalia CLEC19A 34
  • 88.71 (n)
(Bos Taurus)
Mammalia CLEC19A 34 35
  • 88.35 (n)
(Ornithorhynchus anatinus)
Mammalia CLEC19A 35
  • 75 (a)
(Monodelphis domestica)
Mammalia CLEC19A 35
  • 70 (a)
(Gallus gallus)
Aves LOC771758 34
  • 76.97 (n)
CLEC19A 35
  • 58 (a)
(Anolis carolinensis)
Reptilia CLEC19A 35
  • 42 (a)
tropical clawed frog
(Silurana tropicalis)
Amphibia clec19a 34
  • 67.77 (n)
(Danio rerio)
Actinopterygii clec19a 34 35
  • 67.58 (n)
(Caenorhabditis elegans)
Secernentea clec-149 35
  • 9 (a)
Species where no ortholog for CLEC19A was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for CLEC19A Gene

Gene Tree for CLEC19A (if available)
Gene Tree for CLEC19A (if available)

Paralogs for CLEC19A Gene

(1) SIMAP similar genes for CLEC19A Gene using alignment to 3 proteins:

genes like me logo Genes that share paralogs with CLEC19A: view

No data available for Paralogs for CLEC19A Gene

Variants for CLEC19A Gene

Sequence variations from dbSNP and Humsavar for CLEC19A Gene

SNP ID Clin Chr 16 pos Sequence Context AA Info Type
rs1000099485 -- 19,293,981(+) TGGTA(C/T)CAAAT intron-variant
rs1000146555 -- 19,284,309(+) TCTAC(C/T)CGAGG intron-variant, upstream-variant-2KB
rs1000253642 -- 19,290,478(+) GTCCT(C/T)CCCCC intron-variant
rs1000316230 -- 19,311,110(+) CCACC(C/T)CTCCC intron-variant
rs1000517488 -- 19,289,507(+) GACTC(A/G)AGTCT intron-variant

Structural Variations from Database of Genomic Variants (DGV) for CLEC19A Gene

Variant ID Type Subtype PubMed ID
nsv1160368 CNV deletion 26073780
nsv436835 CNV insertion 17901297
nsv571582 CNV gain 21841781
nsv833162 CNV loss 17160897

Variation tolerance for CLEC19A Gene

Gene Damage Index Score: 7.55; 82.41% of all genes are more intolerant (likely to be disease-causing)

Relevant External Links for CLEC19A Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CLEC19A Gene

Disorders for CLEC19A Gene

Relevant External Links for CLEC19A

Atlas of Genetics and Cytogenetics in Oncology and Haematology:

No disorders were found for CLEC19A Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for CLEC19A Gene

Publications for CLEC19A Gene

  1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard D.S. … Malek J. (Genome Res. 2004) 3 4 64
  2. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PMID: 12975309) Clark H.F. … Gray A.M. (Genome Res. 2003) 3 4 64
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg R.L. … Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002) 3 64

Products for CLEC19A Gene

Sources for CLEC19A Gene

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