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Aliases for CLEC18B Gene

Aliases for CLEC18B Gene

  • C-Type Lectin Domain Family 18, Member B 2 3
  • Mannose Receptor-Like Protein 1 3 4
  • C-Type Lectin Domain Family 18 Member B 3
  • Secretory Protein LOC497190 3
  • Mannose Receptor-Like 2 3
  • MRCL2 3
  • MRLP1 4

External Ids for CLEC18B Gene

Previous GeneCards Identifiers for CLEC18B Gene

  • GC16M073002

Summaries for CLEC18B Gene

GeneCards Summary for CLEC18B Gene

CLEC18B (C-Type Lectin Domain Family 18, Member B) is a Protein Coding gene. GO annotations related to this gene include carbohydrate binding. An important paralog of this gene is PI16.

No data available for Entrez Gene Summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for CLEC18B Gene

Genomics for CLEC18B Gene

Regulatory Elements for CLEC18B Gene

Genomic Location for CLEC18B Gene

74,408,270 bp from pter
74,421,953 bp from pter
13,684 bases
Minus strand

Genomic View for CLEC18B Gene

UCSC Golden Path with GeneCards custom track
Cytogenetic band:
Genomic Location for CLEC18B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for CLEC18B Gene

Proteins for CLEC18B Gene

  • Protein details for CLEC18B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    C-type lectin domain family 18 member B
    Protein Accession:
    Secondary Accessions:
    • B4DF90

    Protein attributes for CLEC18B Gene

    455 amino acids
    Molecular mass:
    50490 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for CLEC18B Gene


neXtProt entry for CLEC18B Gene

Proteomics data for CLEC18B Gene at MOPED

Post-translational modifications for CLEC18B Gene

Other Protein References for CLEC18B Gene

No data available for DME Specific Peptides for CLEC18B Gene

Domains for CLEC18B Gene

Gene Families for CLEC18B Gene

Suggested Antigen Peptide Sequences for CLEC18B Gene

GenScript: Design optimal peptide antigens:

Graphical View of Domain Structure for InterPro Entry



  • Contains 1 C-type lectin domain.
  • Contains 1 C-type lectin domain.
  • Contains 1 EGF-like domain.
  • Contains 1 SCP domain.
genes like me logo Genes that share domains with CLEC18B: view

Function for CLEC18B Gene

Gene Ontology (GO) - Molecular Function for CLEC18B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding --
GO:0030246 carbohydrate binding IEA --
genes like me logo Genes that share ontologies with CLEC18B: view

Animal Model Products

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for CLEC18B

In Situ Assay Products

Flow Cytometry Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Animal Models , miRNA , Transcription Factor Targeting and HOMER Transcription for CLEC18B Gene

Localization for CLEC18B Gene

Subcellular locations from UniProtKB/Swiss-Prot for CLEC18B Gene


Subcellular locations from

Jensen Localization Image for CLEC18B Gene COMPARTMENTS Subcellular localization image for CLEC18B gene
Compartment Confidence
extracellular 3
plasma membrane 2
cytosol 1
peroxisome 1

Gene Ontology (GO) - Cellular Components for CLEC18B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005576 extracellular region IEA --
genes like me logo Genes that share ontologies with CLEC18B: view

Pathways for CLEC18B Gene

SuperPathways for CLEC18B Gene

No Data Available

Interacting Proteins for CLEC18B Gene

STRING Interaction Network Preview (showing 4 interactants - click image to see details)
Selected Interacting proteins: ENSP00000341051 for CLEC18B Gene via STRING

Gene Ontology (GO) - Biological Process for CLEC18B Gene


No data available for Pathways by source for CLEC18B Gene

Transcripts for CLEC18B Gene

mRNA/cDNA for CLEC18B Gene

(6) REFSEQ mRNAs :
(4) Additional mRNA sequences :
(6) Ensembl transcripts including schematic representations, and UCSC links where relevant :

Unigene Clusters for CLEC18B Gene

C-type lectin domain family 18, member B:
Representative Sequences:

CRISPR Products

miRNA Products

Inhibitory RNA Products

  • Predesigned siRNA for gene silencing in human,mouse,rat for CLEC18B

Flow Cytometry Products

Alternative Splicing Database (ASD) splice patterns (SP) for CLEC18B Gene

No ASD Table

Relevant External Links for CLEC18B Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for CLEC18B Gene

mRNA expression in normal human tissues for CLEC18B Gene

mRNA differential expression in normal tissues according to GTEx for CLEC18B Gene

This gene is overexpressed in Kidney - Cortex (21.8) and Testis (4.3).

SOURCE GeneReport for Unigene cluster for CLEC18B Gene Hs.454670

genes like me logo Genes that share expressions with CLEC18B: view

Primer Products

  • QuantiTect SYBR Green Assays in human,mouse,rat
  • Pre-validated RT² qPCR Primer Assay in human,mouse,rat
  • QuantiFast Probe-based Assays in human,mouse,rat

In Situ Assay Products

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , mRNA Expression by UniProt/SwissProt and Expression partners for CLEC18B Gene

Orthologs for CLEC18B Gene

This gene was present in the common ancestor of animals.

Orthologs for CLEC18B Gene

Organism Taxonomy Gene Similarity Type Details
(Bos Taurus)
Mammalia MRCL 35
  • 83.06 (n)
  • 80.38 (a)
  • 46 (a)
(Canis familiaris)
Mammalia CLEC18A 35
  • 85.71 (n)
  • 82.77 (a)
-- 36
  • 68 (a)
(Mus musculus)
Mammalia Clec18a 35
  • 82.58 (n)
  • 80.38 (a)
Clec18a 36
  • 63 (a)
(Rattus norvegicus)
Mammalia Clec18a 35
  • 81.92 (n)
  • 80.9 (a)
(Monodelphis domestica)
Mammalia -- 36
  • 72 (a)
(Ornithorhynchus anatinus)
Mammalia -- 36
  • 70 (a)
(Pan troglodytes)
Mammalia -- 36
  • 98 (a)
(Gallus gallus)
Aves CLEC18A 35
  • 72.4 (n)
  • 69.25 (a)
-- 36
  • 65 (a)
(Caenorhabditis elegans)
Secernentea lon-1 36
  • 23 (a)
Species with no ortholog for CLEC18B:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • zebrafish (Danio rerio)

Evolution for CLEC18B Gene

Gene Tree for CLEC18B (if available)
Gene Tree for CLEC18B (if available)

Paralogs for CLEC18B Gene

(2) SIMAP similar genes for CLEC18B Gene using alignment to 1 proteins:

genes like me logo Genes that share paralogs with CLEC18B: view

Variants for CLEC18B Gene

Sequence variations from dbSNP and Humsavar for CLEC18B Gene

SNP ID Clin Chr 16 pos Sequence Context AA Info Type MAF
rs625567 -- 74,415,387(+) CCTCA(A/T)TTTCC intron-variant
rs643113 -- 74,409,270(-) CTGCT(G/T)CCTGG intron-variant
rs710959 -- 74,408,801(-) TGGGG(C/T)CCTTC utr-variant-3-prime
rs710960 -- 74,408,983(+) CCCTC(C/G)CCTGC utr-variant-3-prime
rs2549131 -- 74,414,171(-) TAggc(C/T)gggca intron-variant

Structural Variations from Database of Genomic Variants (DGV) for CLEC18B Gene

Variant ID Type Subtype PubMed ID
dgv2910n71 CNV Gain 21882294
dgv900e1 CNV Complex 17122850
dgv901e1 CNV Complex 17122850
nsv833277 CNV Loss 17160897
esv22159 CNV Gain+Loss 19812545
nsv827736 CNV Gain 20364138
nsv509632 CNV Insertion 20534489
nsv819754 CNV Loss 19587683
nsv9457 CNV Gain+Loss 18304495
dgv488n67 CNV Loss 20364138
dgv2911n71 CNV Gain 21882294
esv32572 CNV Gain 17666407
nsv442726 CNV CNV 18776908
nsv833278 CNV Loss 17160897
nsv821530 CNV Duplication 20802225

Relevant External Links for CLEC18B Gene

HapMap Linkage Disequilibrium report

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for CLEC18B Gene

Disorders for CLEC18B Gene

No disorders were found for CLEC18B Gene.

No data available for MalaCards , OMIM , UniProtKB/Swiss-Prot , University of Copenhagen DISEASES , Novoseek inferred disease relationships , Genatlas and External Links for CLEC18B Gene

Publications for CLEC18B Gene

  1. The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PMID: 12975309) Clark H.F. … Gray A.M. (Genome Res. 2003) 3 4
  2. The C-type lectin-like domain superfamily. (PMID: 16336259) Zelensky A.N. … Gready J.E. (FEBS J. 2005) 3
  3. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K. … Sugano S. (Genome Res. 2006) 3
  4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T. … Sugano S. (Nat. Genet. 2004) 4
  5. The sequence and analysis of duplication-rich human chromosome 16. (PMID: 15616553) Martin J. … Pennacchio L.A. (Nature 2004) 4

Products for CLEC18B Gene

Sources for CLEC18B Gene

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