Aliases for CLEC10A Gene
- C-Type Lectin Domain Family 10, Member A 2 3
- C-Type (Calcium Dependent, Carbohydrate-Recognition Domain) Lectin, Superfamily Member 14 (Macrophage-Derived) 2 3
- Macrophage Lectin 2 (Calcium Dependent) 2 3
- CLECSF13 3 4
- CLECSF14 3 4
- HML 3 4
- C-Type (Calcium Dependent, Carbohydrate-Recognition Domain) Lectin, Superfamily Member 13 (Macrophage-Derived) 3
External Ids for CLEC10A Gene
Previous HGNC Symbols for CLEC10A Gene
Previous GeneCards Identifiers for CLEC10A Gene
This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type 2 transmembrane protein may function as a cell surface antigen. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
GeneCards Summary for CLEC10A Gene
CLEC10A (C-Type Lectin Domain Family 10, Member A) is a Protein Coding gene. Diseases associated with CLEC10A include myopathy with lactic acidosis, hereditary and partial optic atrophy. GO annotations related to this gene include carbohydrate binding. An important paralog of this gene is CLEC4D.
UniProtKB/Swiss-Prot for CLEC10A Gene
Probable role in regulating adaptive and innate immune responses. Binds in a calcium-dependent manner to terminal galactose and N-acetylgalactosamine units, linked to serine or threonine. These sugar moieties are known as Tn-Ag and are expressed in a variety of carcinoma cells.