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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

CLEC10A Gene

protein-coding   GIFtS: 53
GCID: GC17M006977

C-Type Lectin Domain Family 10, Member A

(Previous names: C-type (calcium dependent, carbohydrate-recognition domain)...)
(Previous symbols: CLECSF13, CLECSF14)
  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
C-Type Lectin Domain Family 10, Member A1 2     MGL2 5
CLECSF141 2 3 5     HML22
CLECSF131 2 3     C-Type (Calcium Dependent, Carbohydrate-Recognition Domain) Lectin,
Superfamily Member 13 (Macrophage-Derived)2
HML2 3 5     C-Type Lectin Domain Family 10 Member A2
C-Type (Calcium Dependent, Carbohydrate-Recognition Domain) Lectin,
Superfamily Member 14 (Macrophage-Derived)1 2
     C-Type Lectin Superfamily Member 143
Macrophage Lectin 2 (Calcium Dependent)1 2     CD301 Antigen3
CD3012 5     Macrophage Lectin 23

External Ids:    HGNC: 169161   Entrez Gene: 104622   Ensembl: ENSG000001325147   OMIM: 6059995   UniProtKB: Q8IUN93   

Export aliases for CLEC10A gene to outside databases

Previous GC identifers: GC17M006919 GC17M006923 GC17M006871


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for CLEC10A Gene:
This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this
family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling,
glycoprotein turnover, and roles in inflammation and immune response. The encoded type 2 transmembrane protein
may function as a cell surface antigen. Two transcript variants encoding distinct isoforms have been identified
for this gene. (provided by RefSeq, Jul 2008)

GeneCards Summary for CLEC10A Gene: 
CLEC10A (C-type lectin domain family 10, member A) is a protein-coding gene. Diseases associated with CLEC10A include lown-ganong-levine syndrome, and methylmalonic acidemia. GO annotations related to this gene include carbohydrate binding. An important paralog of this gene is CD207.

UniProtKB/Swiss-Prot: CLC10_HUMAN, Q8IUN9
Function: Probable role in regulating adaptive and innate immune responses. Binds in a calcium-dependent manner to
terminal galactose and N-acetylgalactosamine units, linked to serine or threonine. These sugar moieties are known
as Tn-Ag and are expressed in a variety of carcinoma cells

Gene Wiki entry for CLEC10A Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000017.10  NT_010718.16  NC_018928.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the CLEC10A gene promoter:
         NF-1/L   Spz1   Lmo2   MyoD   Pax-2   Pax-2a   Arnt   PPAR-gamma1   Pax-2b   PPAR-gamma2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCLEC10A promoter sequence
   Search SABiosciences Chromatin IP Primers for CLEC10A

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CLEC10A


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 17p13.1   Ensembl cytogenetic band:  17p13.1   HGNC cytogenetic band: 17p13.2

CLEC10A Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CLEC10A gene location

GeneLoc information about chromosome 17         GeneLoc Exon Structure

GeneLoc location for GC17M006977:  view genomic region     (about GC identifiers)

Start:
6,977,856 bp from pter      End:
6,983,626 bp from pter
Size:
5,771 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: CLC10_HUMAN, Q8IUN9 (See protein sequence)
Recommended Name: C-type lectin domain family 10 member A  
Size: 316 amino acids; 35446 Da
Subcellular location: Membrane; Single-pass type II membrane protein (Probable)
Secondary accessions: A8K8J8 Q14538 Q6PIW3
Alternative splicing: 3 isoforms:  Q8IUN9-1   Q8IUN9-2   Q8IUN9-3   

Explore the universe of human proteins at neXtProt for CLEC10A: NX_Q8IUN9

Explore proteomics data for CLEC10A at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q8IUN9

  • CLEC10A Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    CLEC10A Protein Expression
    REFSEQ proteins (2 alternative transcripts): 
    NP_006335.2  NP_878910.1  

    ENSEMBL proteins: 
     ENSP00000254868   ENSP00000414938   ENSP00000461800   ENSP00000458728   ENSP00000460252  

    Human Recombinant Protein Products for CLEC10A: 
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    Novus Biologicals CLEC10A Proteins
    Novus Biologicals CLEC10A Lysates
    Sino Biological Recombinant Protein for CLEC10A
    Sino Biological Cell Lysate for CLEC10A 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for CLEC10A 

    Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005886plasma membrane TAS8598452
    GO:0016021integral to membrane IEA--

    CLEC10A for ontologies           About GeneDecksing



    CLEC10A Antibody Products: 
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    LSBio Antibodies in human, mouse, rat for CLEC10A 

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    Cloud-Clone Corp. ELISAs for CLEC10A 
    Cloud-Clone Corp. CLIAs for CLEC10A


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    CD: CD molecules
    CLEC: C-type lectin domain containing

    5 InterPro protein domains:
     IPR005640 Lectin_N
     IPR016187 C-type_lectin_fold
     IPR018378 C-type_lectin_CS
     IPR016186 C-type_lectin-like
     IPR001304 C-type_lectin

    Graphical View of Domain Structure for InterPro Entry Q8IUN9

    ProtoNet protein and cluster: Q8IUN9

    2 Blocks protein domains:
    IPB002353 Type II antifreeze protein signature
    IPB005640 Hepatic lectin


    UniProtKB/Swiss-Prot: CLC10_HUMAN, Q8IUN9
    Similarity: Contains 1 C-type lectin domain


    CLEC10A for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: CLC10_HUMAN, Q8IUN9
    Function: Probable role in regulating adaptive and innate immune responses. Binds in a calcium-dependent manner to
    terminal galactose and N-acetylgalactosamine units, linked to serine or threonine. These sugar moieties are known
    as Tn-Ag and are expressed in a variety of carcinoma cells

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0030246carbohydrate binding IEA--
         
    CLEC10A for ontologies           About GeneDecksing


    Phenotypes:
         1 MGI phenotypic allele for Mgl2 (no phenotypes)

    CLEC10A for phenotypes           About GeneDecksing

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for CLEC10A 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for CLEC10A

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for CLEC10A 
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for CLEC10A 

    miRNA
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    1 QIAGEN miScript miRNA Assays for microRNA that regulate CLEC10A:
    hsa-miR-3144-3p
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    Inhib. RNA
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    Gene Editing
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    Clone
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    GenScript: all cDNA clones in your preferred vector (see all 2): CLEC10A (NM_006344)
    Sino Biological Human cDNA Clone for CLEC10A
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                         Customized lentivirus expression plasmids for stable overexpression of CLEC10A 

    Cell Line
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    In Situ Assay
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CLEC10A


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section




    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CLEC10A

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006897endocytosis IEA--
    GO:0045087innate immune response IEA--

    CLEC10A for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section

    CLEC10A for compounds           About GeneDecksing

    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for CLEC10A (CLC10)

    1 HMDB Compound for CLEC10A    About this table
    CompoundSynonyms CAS #PubMed Ids
    CalciumCa (see all 2)7440-70-2--

    1 Novoseek inferred chemical compound relationship for CLEC10A gene    About this table
    Compound   -log (P-Val)   Hits   PubMed IDs for Articles with Shared Sentences (# sentences)
    galactose 59.4 1 14990712 (1)

    Search CenterWatch for drugs/clinical trials and news about CLEC10A / CLC10

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for CLEC10A gene (2 alternative transcripts): 
    NM_006344.2  NM_182906.2  

    Unigene Cluster for CLEC10A:

    C-type lectin domain family 10, member A
    Hs.54403  [show with all ESTs]
    Unigene Representative Sequence: BC027858
    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000254868(uc002gej.3 uc002gek.3) ENST00000416562 ENST00000576549
    ENST00000576617(uc010clv.2) ENST00000571664 ENST00000571624
    miRNA
    Products:
         
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat CLEC10A
    1 QIAGEN miScript miRNA Assays for microRNA that regulate CLEC10A:
    hsa-miR-3144-3p
    SwitchGear 3'UTR luciferase reporter plasmidCLEC10A 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for CLEC10A
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CLEC10A
    Clone
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    OriGene clones in human, mouse for CLEC10A (see all 13)
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    GenScript: all cDNA clones in your preferred vector (see all 2): CLEC10A (NM_006344)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CLEC10A
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CLEC10A
    Sirion Biotech Customized lentivirus for stable overexpression of CLEC10A 
                         Customized lentivirus expression plasmids for stable overexpression of CLEC10A 
    Primer
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      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CLEC10A
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CLEC10A

    Additional mRNA sequence: 

    AK291975.1 AK292363.1 BC027858.1 BC039011.1 D50532.1 

    3 DOTS entries:

    DT.303878  DT.95309700  DT.97815987 

    24/51 AceView cDNA sequences (see all 51):

    BM675204 BM974488 CA418829 BM714409 AW173547 BX282000 BU621880 BI820020 
    CA412958 BU687211 BI821633 CR620226 AI078064 BP377240 BM988225 BV196270 
    BQ067335 BP338480 BI910082 BI767532 BC027858 AL546075 BI770754 BC039011 

    GeneLoc Exon Structure

    6 Alternative Splicing Database (ASD) splice patterns (SP) for CLEC10A (see first 5)    About this scheme

    ExUns: 1a · 1b · 1c · 1d ^ 2a · 2b ^ 3 ^ 4a · 4b ^ 5 ^ 6a · 6b · 6c · 6d ^ 7a · 7b ^ 8 ^ 9a · 9b
    SP1:                                -                                               -                                 
    SP2:                                -                             -                                                   
    SP3:                                -                             -                 -                                 
    SP4:                                -                             -                                                   
    SP5:                                                              -                 -                                 
    SP6:                                                                                                                  


    ECgene alternative splicing isoforms for CLEC10A

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    CLEC10A expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: AAGGTATAAT
    CLEC10A Expression
    About this image


    See CLEC10A Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for CLEC10A

    SOURCE GeneReport for Unigene cluster: Hs.54403
        SABiosciences Custom PCR Arrays for CLEC10A
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CLEC10A

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for CLEC10A gene from 3/8 species (see all 8)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Mgl21 , 5 macrophage galactose N-acetyl-galactosamine specific more1, 5 68.83(n)1
    55.52(a)1
      11 (42.99 cM)5
    2168641  NM_145137.21  NP_660119.11 
     701303295 
    lizard
    (Anolis carolinensis)
    Reptilia --
    Uncharacterized protein
    36(a)
    possible ortholog
    2(80104375-80116126)
    zebrafish
    (Danio rerio)
    Actinopterygii LOC7992691 asialoglycoprotein receptor 2-like 46.04(n)
    36.07(a)
      799269  XM_001339609.3  XP_001339645.1 


    ENSEMBL Gene Tree for CLEC10A (if available)
    TreeFam Gene Tree for CLEC10A (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for CLEC10A gene
    CD2072  CLEC17A2  CLEC4E2  ASGR22  CLEC4M2  CLEC4F2  CD2092  CLEC4A2  
    FCER22  CLEC6A2  ASGR12  CLEC4C2  CLEC4D2  CLEC4G2  
    18 SIMAP similar genes for CLEC10A using alignment to 4 protein entries:     CLC10_HUMAN (see all proteins):
    ASGR1    HBXBP    FCER2    ASGR2    KLRF1    CLEC2D
    CLEC4C    KLRG1    OLR1    CLEC4E    CLEC6A    CLEC2L
    KLRC1    REG1B    CLEC1B    CD209    CLEC4A    KLRC2

    CLEC10A for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/289 SNPs in CLEC10A are shown (see all 289)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 17 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs769310261,2
    C--6965261(+) CAGAGA/CCAGCC 2 -- ds50010--------
    rs1832629131,2
    --6965334(+) GACCAC/TGGACG 2 -- ds50010--------
    rs4157041,2
    C,F,A,H--6965548(-) TTAGGG/ATGATT 2 -- ds500122Minor allele frequency- A:0.47NS EA NA WA CSA 1178
    rs1869879671,2
    --6965632(+) TCACAC/TAGGAC 2 -- ds50010--------
    rs2011633431,2
    --6965683(+) GATTG-/CCCAAA 2 -- ds50010--------
    rs1491058061,2
    C--6965756(+) TACACA/GAGAGT 2 -- ut310--------
    rs1164286931,2
    F--6965775(+) TCACTT/GATATG 2 -- ut311Minor allele frequency- G:0.01WA 118
    rs16982251,2
    C,F,H--6965860(-) CCAACC/GACTTC 2 -- ut31 ese315Minor allele frequency- G:0.07EA NA NS CSA WA 970
    rs37857981,2
    C,F,H--6965919(-) CGATCG/ACAATA 2 -- ut31 ese38Minor allele frequency- A:0.07NS EA 968
    rs37857961,2
    C--6966032(-) CCAACG/TTTTGA 2 -- ut310--------

    HapMap Linkage Disequilibrium report for CLEC10A (6977856 - 6983626 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 6 variations for CLEC10A:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2669929CNV Deletion23128226
    esv2422288CNV Deletion17116639
    esv2657406CNV Deletion23128226
    esv5167CNV Deletion18987735
    nsv907635CNV Loss21882294
    nsv457659CNV Loss19166990

    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing CLEC10A
    DNA2.0 Custom Variant and Variant Library Synthesis for CLEC10A

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 605999    OMIM disorders: --

    4 diseases for CLEC10A:    About MalaCards
    lown-ganong-levine syndrome    methylmalonic acidemia    hepatitis b    hepatitis


    CLEC10A for disorders           About GeneDecksing

    Genetic Association Database (GAD): CLEC10A
    Human Genome Epidemiology (HuGE) Navigator: CLEC10A (2 documents)

    Export disorders for CLEC10A gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for CLEC10A gene, integrated from 9 sources (see all 15):
    (articles sorted by number of sources associating them with CLEC10A)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Molecular cloning and expression of cDNA encoding human macrophage c- type lectin: its unique carbohydrate binding specificity for Tn antigen. (PubMed id 8598452)1, 2, 3, 9 Suzuki N.... Irimura T. (1996)
    2. Single nucleotide polymorphism of TAG-1 influences IV Ig responsiveness of Japanese patients with CIDP. (PubMed id 19776380)1, 4 Iijima M....Sobue G. (2009)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    4. Protein domain histochemistry (PDH): binding of the ca rbohydrate recognition domain (CRD) of recombinant human glycoreceptor CLEC10A ( CD301) to formalin-fixed, paraffin-embedded breast cancer tissues. (PubMed id 23275449)1 Nollau P....Wagener C. (2013)
    5. Targeting of macrophage galactose-type C-type lectin ( MGL) induces DC signaling and activation. (PubMed id 22531918)1 Napoletano C....Nuti M. (2012)
    6. New genetic associations detected in a host response study to hepatitis B vaccine. (PubMed id 20237496)1 Davila S....Seielstad M. (2010)
    7. Variation of Neisseria gonorrhoeae lipooligosaccharid e directs dendritic cell-induced T helper responses. (PubMed id 19834553)1 van Vliet S.J....van Kooyk Y. (2009)
    8. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)2 Ota T.... Sugano S. (2004)
    9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (2002)
    10. Normalization and subtraction: two approaches to facilitate gene discovery. (PubMed id 8889548)1 Bonaldo M.F.... Soares M.B. (1996)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 10462 HGNC: 16916 AceView: CLECSF14 Ensembl:ENSG00000132514 euGenes: HUgn10462
    ECgene: CLEC10A H-InvDB: CLEC10A

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for CLEC10A Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for CLEC10A Genetics and Cytogenetics in Oncology and Haematology
    Functional Glycomics Gateway - Glycan Bindinghttp://www.functionalglycomics.org/glycomics/GBPServlet?&operationType=view&cbpId=cbp_hum_Ctlect_217

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for CLEC10A gene:
    Search GeneIP for patents involving CLEC10A

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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