Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 
or upload a file of gene symbols


Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

CLDN20 Gene

protein-coding   GIFtS: 48
GCID: GC06P155677

Claudin 20

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Claudin 201 2
claudin-202

External Ids:    HGNC: 20421   Entrez Gene: 498612   Ensembl: ENSG000001712177   UniProtKB: P568803   

Export aliases for CLDN20 gene to outside databases

Previous GC identifers: GC06P155146 GC06M155480 GC06P155540 GC06P155616 GC06P155627 GC06P153147


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for CLDN20 Gene:
This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight
junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing
freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles
in maintaining cell polarity and signal transductions. (provided by RefSeq, Jun 2010)

GeneCards Summary for CLDN20 Gene: 
CLDN20 (claudin 20) is a protein-coding gene. Diseases associated with CLDN20 include endotheliitis, and hepatitis c, and among its related super-pathways are Cell-cell junction organization and Sertoli-Sertoli Cell Junction Dynamics. GO annotations related to this gene include structural molecule activity and identical protein binding. An important paralog of this gene is CLDN4.

UniProtKB/Swiss-Prot: CLD20_HUMAN, P56880
Function: Plays a major role in tight junction-specific obliteration of the intercellular space, through
calcium-independent cell-adhesion activity (By similarity)

Gene Wiki entry for CLDN20 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000006.11  NC_018917.2  NT_025741.15  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the CLDN20 gene promoter:
         Pbx1a   Brachyury   YY1   PPAR-gamma1   CBF-A   CBF-B   CP1A   PPAR-gamma2   NF-Y   CBF(2)   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCLDN20 promoter sequence
   Search SABiosciences Chromatin IP Primers for CLDN20

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CLDN20


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 6q25   Ensembl cytogenetic band:  6q25.3   HGNC cytogenetic band: 6q25

CLDN20 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CLDN20 gene location

GeneLoc information about chromosome 6         GeneLoc Exon Structure

GeneLoc location for GC06P155677:  view genomic region     (about GC identifiers)

Start:
155,585,147 bp from pter      End:
155,597,682 bp from pter
Size:
12,536 bases      Orientation:
plus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: CLD20_HUMAN, P56880 (See protein sequence)
Recommended Name: Claudin-20  
Size: 219 amino acids; 23515 Da
Subcellular location: Cell junction, tight junction. Cell membrane; Multi-pass membrane protein

Explore the universe of human proteins at neXtProt for CLDN20: NX_P56880

Explore proteomics data for CLDN20 at MOPED 

CLDN20 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

CLDN20 Protein Expression

REFSEQ proteins: NP_001001346.1  
ENSEMBL proteins: 
 ENSP00000356133  
Reactome Protein details: P56880
Human Recombinant Protein Products for CLDN20: 
Browse Purified and Recombinant Proteins at EMD Millipore
Browse R&D Systems for human recombinant proteins
Browse recombinant and purified proteins available from Enzo Life Sciences
Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
OriGene Protein Over-expression Lysate for CLDN20
OriGene Custom MassSpec 
OriGene Custom Protein Services for CLDN20
GenScript Custom Purified and Recombinant Proteins Services for CLDN20
Novus Biologicals CLDN20 Protein
Novus Biologicals CLDN20 Lysates
Browse Sino Biological Recombinant Proteins
Browse Sino Biological Cell Lysates 
Browse ProSpec Recombinant Proteins
Cloud-Clone Corp. Proteins for CLDN20 

Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005886plasma membrane IEA--
GO:0005923tight junction ISS--
GO:0016021integral to membrane IEA--

CLDN20 for ontologies           About GeneDecksing



CLDN20 Antibody Products: 
Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
Browse R&D Systems for Antibodies
Browse OriGene Antibodies
OriGene Custom Antibody Services for CLDN20
GenScript Custom Superior Antibodies Services for CLDN20
Novus Biologicals CLDN20 Antibodies
Abcam antibodies for CLDN20
Cloud-Clone Corp. Antibodies for CLDN20 
Search ThermoFisher Antibodies for CLDN20
Search LSBio for Antibodies for CLDN20 

Assay Products for CLDN20: 
Browse Kits and Assays available from EMD Millipore
OriGene Custom Assay Services for CLDN20
Browse R&D Systems for biochemical assays
GenScript Custom Assay Services for CLDN20
Browse Enzo Life Sciences for kits & assays
Cloud-Clone Corp. ELISAs for CLDN20 
Cloud-Clone Corp. CLIAs for CLDN20


(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section
HGNC Gene Families: 
CLDN: Claudins

3 InterPro protein domains:
 IPR017974 Claudin_CS
 IPR006187 Claudin
 IPR004031 PMP22/EMP/MP20/Claudin

Graphical View of Domain Structure for InterPro Entry P56880

ProtoNet protein and cluster: P56880

1 Blocks protein domain: IPB006187 Claudin family signature

UniProtKB/Swiss-Prot: CLD20_HUMAN, P56880
Similarity: Belongs to the claudin family


CLDN20 for domains           About GeneDecksing


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
About This Section

Molecular Function:

     UniProtKB/Swiss-Prot Summary: CLD20_HUMAN, P56880
Function: Plays a major role in tight junction-specific obliteration of the intercellular space, through
calcium-independent cell-adhesion activity (By similarity)

     Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005198structural molecule activity IEA--
GO:0042802identical protein binding ISS--
     
CLDN20 for ontologies           About GeneDecksing


Animal Models:
   inGenious Targeting Laboratory - Custom generated mouse model solutions for CLDN20 
   inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for CLDN20

   genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for CLDN20 
   genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for CLDN20 

miRNA
Products:
    
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat CLDN20
Search QIAGEN for miScript miRNA Assays for microRNAs that regulate CLDN20
SwitchGear 3'UTR luciferase reporter plasmidCLDN20 3' UTR sequence
Inhib. RNA
Products:
    
Browse for Gene Knock-down Tools from EMD Millipore
OriGene RNAi products in human, mouse, rat for CLDN20
QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CLDN20

Gene Editing
Products:
DNA2.0 Custom Protein Engineering Service for CLDN20
Sirion Biotech Customized adenovirus for overexpression of CLDN20

Clone
Products:
     
Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
OriGene clones in human, mouse for CLDN20 (see all 6)
OriGene ORF clones in mouse, rat for CLDN20
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector: CLDN20 (NM_001001346)
Browse Sino Biological Human cDNA Clones
DNA2.0 Custom Codon Optimized Gene Synthesis Service for CLDN20
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CLDN20
Sirion Biotech Customized lentivirus for stable overexpression of CLDN20 
                     Customized lentivirus expression plasmids for stable overexpression of CLDN20 

Cell Line
Products:
     
GenScript Custom overexpressing Cell Line Services for CLDN20
Search LifeMap BioReagents cell lines for CLDN20
In Situ Assay
Products:
   

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CLDN20


(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
About This Section

SuperPaths for CLDN20 About   (see all 7)                                                                                              See pathways by source

SuperPathContained pathways About
1Cell-cell junction organization
Cell-cell junction organization0.69
Cell-Cell communication0.64
Cell junction organization0.69
Tight junction interactions0.49
2Sertoli-Sertoli Cell Junction Dynamics
Sertoli-Sertoli Cell Junction Dynamics0.38
Epithelial Tight Junctions0.36
3Integrin Pathway
Transendothelial Migration of Leukocytes0.38
4Tight junction
Tight junction
5Leukocyte transendothelial migration
Leukocyte transendothelial migration

Pathways by source                                                                                                                                                                 See SuperPaths
Show all pathways

3 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for CLDN20
    Sertoli-Sertoli Cell Junction Dynamics
Epithelial Tight Junctions
Transendothelial Migration of Leukocytes

4        Reactome Pathways for CLDN20
    Tight junction interactions
Cell junction organization
Cell-Cell communication
Cell-cell junction organization


4         Kegg Pathways  (Kegg details for CLDN20):
    Cell adhesion molecules (CAMs)
Tight junction
Leukocyte transendothelial migration
Hepatitis C


CLDN20 for pathways           About GeneDecksing

Interactions:

    Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CLDN20

STRING Interaction Network Preview (showing 5 interactants - click image to see 25)

5/26 Interacting proteins for CLDN20 (ENSP000003561334) via UniProtKB, MINT, STRING, and/or I2D (see all 26)
InteractantInteraction Details
GeneCardExternal ID(s)
CLDN12ENSP000002879164STRING: ENSP00000287916
CLDN14ENSP000003392924STRING: ENSP00000339292
CLDN15ENSP000003088704STRING: ENSP00000308870
CLDN17ENSP000002868084STRING: ENSP00000286808
CLDN18ENSP000001836054STRING: ENSP00000183605
About this table

Gene Ontology (GO): 4 biological process terms (GO ID links to tree view):    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0016338calcium-independent cell-cell adhesion ISS--
GO:0034329cell junction assembly TAS--
GO:0045216cell-cell junction organization TAS--
GO:0070830tight junction assembly TAS--

CLDN20 for ontologies           About GeneDecksing



(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section
Browse Small Molecules at EMD Millipore
Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for CLDN20 (CLD20)

1 HMDB Compound for CLDN20    About this table
CompoundSynonyms CAS #PubMed Ids
CalciumCa (see all 2)7440-70-2--

Search CenterWatch for drugs/clinical trials and news about CLDN20 / CLD20

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for CLDN20 gene: 
NM_001001346.3  

Unigene Cluster for CLDN20:

Claudin 20
Hs.567491  [show with all ESTs]
Unigene Representative Sequence: BC020838
1 Ensembl transcript including schematic representation, and UCSC links where relevant:
ENST00000367165(uc003qql.2)
miRNA
Products:
     
QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat CLDN20
Search QIAGEN for miScript miRNA Assays for microRNAs that regulate CLDN20
SwitchGear 3'UTR luciferase reporter plasmidCLDN20 3' UTR sequence
Inhib. RNA
Products:
     
Browse for Gene Knock-down Tools from EMD Millipore
OriGene RNAi products in human, mouse, rat for CLDN20
QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CLDN20
Clone
Products:
     
OriGene clones in human, mouse for CLDN20 (see all 6)
OriGene ORF clones in mouse, rat for CLDN20
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector: CLDN20 (NM_001001346)
DNA2.0 Custom Codon Optimized Gene Synthesis Service for CLDN20
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CLDN20
Sirion Biotech Customized lentivirus for stable overexpression of CLDN20 
                     Customized lentivirus expression plasmids for stable overexpression of CLDN20 
Primer
Products:
    
OriGene qPCR primer pairs and template standards for CLDN20
OriGene qSTAR qPCR primer pairs in human, mouse for CLDN20
SABiosciences RT2 qPCR Primer Assay in human, mouse, rat CLDN20
  QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CLDN20
  QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CLDN20

Additional mRNA sequence: BC020838.1 

1 DOTS entry:

DT.95099967 

5 AceView cDNA sequences:

BX283198 BC020838 NM_001001346 BF571834 BG980450 

GeneLoc Exon Structure


(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

CLDN20 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: AACCTGGAGG
CLDN20 Expression
About this image


See CLDN20 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for CLDN20

SOURCE GeneReport for Unigene cluster: Hs.567491
    SABiosciences Custom PCR Arrays for CLDN20
Primer
Products:
OriGene qPCR primer pairs and template standards for CLDN20
OriGene qSTAR qPCR primer pairs in human, mouse for CLDN20
SABiosciences RT2 qPCR Primer Assay in human, mouse, rat CLDN20
QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CLDN20
QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CLDN20
In Situ
Assay Products:
 

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CLDN20

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of chordates.

Orthologs for CLDN20 gene from 4/9 species (see all 9)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
mouse
(Mus musculus)
Mammalia Cldn201 , 5 claudin 201, 5 79.91(n)1
74.43(a)1
  17 (2.01 cM)5
6216281  NM_001101560.11  NP_001095030.11 
 35325545 
chicken
(Gallus gallus)
Aves CLDN201 claudin 20 73.06(n)
67.12(a)
  769340  XM_001232002.1  XP_001232003.1 
lizard
(Anolis carolinensis)
Reptilia CLDN206
Uncharacterized protein
68(a)
1 ↔ 1
1(214601671-214602333)
zebrafish
(Danio rerio)
Actinopterygii LOC1003302461 claudin-20-like 59.9(n)
52.17(a)
  100330246  XM_002667609.2  XP_002667655.2 


ENSEMBL Gene Tree for CLDN20 (if available)
TreeFam Gene Tree for CLDN20 (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
Paralogs for CLDN20 gene
CLDN42  CLDN92  CLDN82  CLDN172  CLDN52  CLDN102  CLDN22  CLDN152  
CLDN12  CLDN32  CLDN142  CLDN62  CLDN72  CLDN192  
17 SIMAP similar genes for CLDN20 using alignment to 1 protein entry:     CLD20_HUMAN:
CLDN7    CLDN2    CLDN4    CLDN6    CLDN1    CLDN14
CLDN19    CLDN3    CLDN18    CLDN10    CLDN9    CLDN15
CLDN5    CLDN8    CLDN17    CLDN24    CLDN22

CLDN20 for paralogs           About GeneDecksing



(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
Structural Variations
     Database of Genomic Variants (DGV) 2 variations for CLDN20:    About this table     
Variant IDTypeSubtypePubMed ID
nsv886790CNV Loss21882294
nsv886789CNV Gain21882294

SABiosciences Cancer Mutation PCR Assays
SeqTarget long-range PCR primers for resequencing CLDN20
DNA2.0 Custom Variant and Variant Library Synthesis for CLDN20

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section
4 diseases for CLDN20:    About MalaCards
endotheliitis    hepatitis c    retinitis    hepatitis


CLDN20 for disorders           About GeneDecksing

Genetic Association Database (GAD): CLDN20

Export disorders for CLDN20 gene to outside databases

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
About This Section

PubMed articles for CLDN20 gene, integrated from 9 sources (see all 18):
(articles sorted by number of sources associating them with CLDN20)
    Utopia: connect your pdf to the dynamic
world of online information

  1. The claudin gene family: expression in normal and neoplastic tissues. (PubMed id 16836752)1, 3 Hewitt K.J....Morin P.J. (2006)
  2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
  3. The DNA sequence and analysis of human chromosome 6. (PubMed id 14574404)1, 2 Mungall A.J.... Beck S. (2003)
  4. Analysis of the RPE transcriptome reveals dynamic changes during the development of the outer blood-retinal barrier. (PubMed id 17679949)1, 9 Rizzolo L.J....Zhang H. (2007)
  5. Interactions of pathological hallmark proteins: tubul in polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)1 OlA!h J....OvA!di J. (2011)
  6. The claudins. (PubMed id 19706201)1 Lal-Nag M. and Morin P.J. (2009)
  7. Biology of claudins. (PubMed id 18480174)1 Angelow S....Yu A.S. (2008)
  8. Structure and function of claudins. (PubMed id 18036336)1 Krause G....Blasig I.E. (2008)
  9. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)1 Lamesch P.... Vidal M. (2007)
  10. Genome-wide association and linkage analyses of hemostatic factors and hematological phenotypes in the Framingham Heart Study. (PubMed id 17903294)4 Yang Q....O'Donnell C.J. (2007)

(in PubMed, OMIM, and NCBI Bookshelf)
About This Section
 ANDOR
Aliases
Free Text  

  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section
Entrez Gene: 49861 HGNC: 2042 AceView: CLDN20 Ensembl:ENSG00000171217 euGenes: HUgn49861
ECgene: CLDN20 Kegg: 49861 H-InvDB: CLDN20

(According to HUGE)
About This Section
  --

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
NameDescription
PharmGKB entry for CLDN20 Pharmacogenomics, SNPs, Pathways

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
About This Section
Patent Information for CLDN20 gene:
Search GeneIP for patents involving CLDN20

GeneCards and IP:
Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Sirion Biotech, Cell lines from GenScript, and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
About This Section

 
 EMD Millipore Custom Antibody & Bulk Services
 EMD Millipore Preclinical / Clinical Development Services
 EMD Millipore Immunoassay Services
 EMD Millipore Target Screening & Profiling Services

  
 Browse Antibodies   Browse Cell Culture Products  
 Browse ELISAs   Browse Flow Cytometry Kits  
 Browse Primer Pairs   Browse Kinase Activity Assays/Reagents  
 Browse ELISpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
 Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
 Browse DNA Damage/Repair Kits/Reagents   Browse Multiplex/Array Assay Kits/Reagents  
 Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
 Browse Protease Activity Assays and Reagents   Browse Recombinant/Natural Proteins  
 Browse Stem Cell Products   Browse Tocris Biochemicals & Compounds  
 cDNA Clones for CLDN20 (Claudin-20)   Browse Proteome Profiler Antibody Arrays  
 Browse OriGene Antibodies   OriGene RNAi products in human, mouse, rat for CLDN20  
 OriGene qPCR primer pairs and template standards for CLDN20   OriGene Protein Over-expression Lysate for CLDN20  
 OriGene Custom Mass Spec   OriGene clones in human, mouse for CLDN20  
 OriGene qSTAR qPCR primer pairs in human, mouse for CLDN20   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
 OriGene ORF clones in mouse, rat for CLDN20   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
 OriGene Custom Antibody Services for CLDN20   OriGene Custom Protein Services for CLDN20  

 
 
 QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat CLDN20
 QIAGEN SeqTarget long-range PCR primers for resequencing CLDN20
 QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CLDN20
 QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CLDN20
 QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CLDN20
 QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CLDN20
 GenScript Custom Purified and Recombinant Proteins Services for CLDN20 GenScript cDNA clones with any tag delivered in your preferred vector for CLDN20
 GenScript Custom Assay Services for CLDN20 GenScript Custom Superior Antibodies Services for CLDN20
 GenScript Custom overexpressing Cell Line Services for CLDN20 CloneReady with Over 120,000 Genes
 Gene Synthesis: Any Gene in Any Vector Vector-based siRNA and miRNA, Ready for Transfection
 Gene Mutant Library, Variants up to 10^11 Plasmid Preparation
 Custom Peptide Services
 Search for Antibodies & Assays

 Regulatory tfbs in CLDN20 promoter
 Search Chromatin IP Primers for CLDN20
 RT2 qPCR Primer Assay in human, mouse, rat CLDN20
 Search GNC Networks for CLDN20
 SABiosciences PCR Arrays including human, mouse, rat CLDN20
 Search Tocris compounds for CLDN20 (CLD20)
 Browse Sino Biological Proteins and Antibodies
 Browse Sino Biological Cell Lysates
 Browse Sino Biological cDNA Clones
 4000+ Proteins
 Search Sino Biological for antibodies, proteins & pathways
 Protein Production Services
 Transfection Reagents
 Protein A/G/L resins
 Isotyping reagents
 Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies
 Novus Tissue Slides
 CLDN20 antibodies
 CLDN20 proteins
 CLDN20 lysates
 Antibodies for CLDN20
 See all of Abcam's Antibodies, Kits and Proteins for CLDN20
 Custom Antibody / Protein Production Service
 Bulk Purchasing
 Advantages of Rabbit Monoclonal antibodies
 Abcam protocols and scientific support
 Browse ProSpec Recombinant Proteins




 Proteins for CLDN20
 Antibodies for CLDN20
 ELISAs for CLDN20
 CLIAs for CLDN20
 Search LifeMap BioReagents cell lines for CLDN20
 Gene Synthesis
 Protein Engineering
 Variant Library Synthesis
 Codon Optimization
 Protein Production and Purification
 Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CLDN20
 SwitchGear 3'UTR luciferase reporter plasmids for CLDN20
 SwitchGear Promoter luciferase reporter plasmids for CLDN20
 Search ThermoFisher Antibodies for CLDN20
 Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CLDN20
 inGenious Targeting Laboratory - Custom generated mouse model solutions for CLDN20
 inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for CLDN20
Customized:
 lentivirus for stable overexpression of CLDN20
 lentivirus expression plasmids for stable overexpression of CLDN20
 adenovirus for overexpression of CLDN20
 Search LSBio for Antibodies for CLDN20
Customized transgenic rodents for:
 Humanization
 Biomarker expression
 Off-target effect monitoring
 Translational medicine
 Tissue-specific gene expresssion
 Time-controlled gene expresssion
       
GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

View Random Gene

Category
(GIFtS: 73)
transforming growth factor, beta 1
GIFtS Group
The GeneCards human gene database gene index: 1 3 5 6 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

Hot genes      Disease genes      CLDN20 gene at Home site.
hostname: 356980-web2.xennexinc.com index build: 106 solr: 1.4