CLDN14 Gene
protein-coding GIFtS: 65
GCID: GC21M037832
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claudin 14 (Previous symbol: DFNB29)
| |
Aliases for CLDN14 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
10fRNAdb, and/or 11Nature:405,311-319 and CroW21) About This Section
|
| Aliases |
|---|
| Claudin 141 2 | | DFNB291 2 5 | | Human CLDN14 Gene11 | | Claudin-141 |
Export aliases for CLDN14 gene to outside databasesPrevious GC identifers: GC21M034410 GC21M036753 GC21M036754 GC21M023308 |
Summaries for CLDN14 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| Entrez Gene summary for CLDN14: Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, formingcontinuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freelythrough the paracellular space. These junctions are comprised of sets of continuous networking strands in theoutwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. Theprotein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tightjunction strands. The encoded protein also binds specifically to the WW domain of Yes-associated protein. Defects inthis gene are the cause of an autosomal recessive form of nonsyndromic sensorineural deafness. It is also reportedthat four synonymous variants in this gene are associated with kidney stones and reduced bone mineral density. Severaltranscript variants encoding the same protein have been found for this gene. (provided by RefSeq, Jun 2010) UniProtKB/Swiss-Prot: CLD14_HUMAN, O95500Function: Plays a major role in tight junction-specific obliteration of the intercellular space, throughcalcium-independent cell-adhesion activity (By similarity) Gene Wiki entry for CLDN14
|
Genomic Views for CLDN14 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics, Whole Chromsome Sequence According to
Nature (Cited Here with Permission):405,311-319 and CroW21) About This Section
|
| GC21M037832: |
GeneLoc |
Nature:405,311-319 |
Start:
|
37,832,919 bp from pter |
23,409,717 bp from centromere |
End:
|
37,948,867 bp from pter |
23,410,436 bp from centromere |
Size:
|
115,949 bases |
720 bases |
Orientation:
|
minus strand |
minus strand |
Proteins for CLDN14 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
| UniProtKB/Swiss-Prot: CLD14_HUMAN, O95500 (See
protein sequence)Recommended Name: Claudin-14 Size: 239 amino acids; 25699 Da
Subcellular location: Cell junction, tight junction. Cell membrane; Multi-pass membrane proteinExplore the universe of human proteins at neXtProt for CLDN14: NX_O95500
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_O95500 CLDN14 Protein expression data from MOPED and PaxDb: About this image 
 REFSEQ proteins (5 alternative transcripts):
NP_001139549.1 NP_001139550.1 NP_001139551.1 NP_036262.1 NP_652763.1 ENSEMBL proteins: ENSP00000382092 ENSP00000382090 ENSP00000382087 ENSP00000382088 ENSP00000339292 Reactome Protein details: O95500 Human Recombinant Protein Products for CLDN14:
Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view): About this table
CLDN14 for ontologies About GeneDecksing
CLDN14 Antibody Products: Assay Products for CLDN14: |
Protein
Domains / Families for CLDN14 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
CLDN14 for domains About GeneDecksing
4 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry O95500ProtoNet protein and cluster: O95500 2 Blocks protein families: IPB003556 Claudin-14 signature IPB006187 Claudin family signature
UniProtKB/Swiss-Prot: CLD14_HUMAN, O95500Similarity: Belongs to the claudin family |
Function for CLDN14 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
| Molecular Function: UniProtKB/Swiss-Prot Summary: CLD14_HUMAN, O95500Function: Plays a major role in tight junction-specific obliteration of the intercellular space, throughcalcium-independent cell-adhesion activity (By similarity) Genatlas biochemistry entry for CLDN14:claudin 14,clostridium perfringens enterotoxin receptor-like,integral membrane protein,claudin family of majorstructural components of tight junction (TJ) strands
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005198 | structural molecule activity |
IEA | -- | | GO:0042802 | identical protein binding |
ISS | -- |
CLDN14 for ontologies About GeneDecksing
Phenotypes: 5 GenomeRNAi human phenotypes for CLDN14: 3 MGI mutant phenotypes (inferred from 2 alleles ) (MGI details for Cldn14):
CLDN14 for phenotypes About GeneDecksing
Animal Models: Mouse knock-out Cldn14tm1Lex for CLDN14
Clone Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CLDN14 (see all 9) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CLDN14 (see all 5) OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 5): CLDN14 (NM_144492) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CLDN14 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CLDN14  |
In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CLDN14 |
|
Pathways & Interactions for CLDN14 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
| Unified GeneCards pathways - 5/9 super-pathways (see all 9) About this table  See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Cell-cell junction organization | | | 2 | Cell adhesion Tight junctions | | | 3 | Cell adhesion Endothelial cell contacts by junctional mechanisms | | | 4 | Sertoli-Sertoli Cell Junction Dynamics | | | 5 | Hepatitis C | |
Pathway sources See GeneCards unified pathways Show all pathways
2 EMD Millipore Pathways for CLDN14 3 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for CLDN14 2 GeneGo (Thomson Reuters) Pathways for CLDN14 4
Reactome Pathways for CLDN14
4
Kegg Pathways (Kegg details for CLDN14):
CLDN14 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CLDN14
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
 5/26 Interacting proteins for CLDN14 (ENSP000003392924) via UniProtKB, MINT, STRING, and/or I2D (see all 26)About this table
Gene Ontology (GO): 5 biological process terms (GO ID links to tree view): About this table
CLDN14 for ontologies About GeneDecksing
|
Drugs & Compounds for CLDN14 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
Browse Tocris compounds for CLDN14
1 HMDB Compound for CLDN14 About this table Search CenterWatch for drugs/clinical trials and news about CLDN14 / CLD14 
|
Transcripts for CLDN14 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
) About This Section
| REFSEQ mRNAs for CLDN14 gene (5 alternative transcripts): NM_001146077.1 NM_001146078.2 NM_001146079.1 NM_012130.3 NM_144492.2 Unigene Cluster for CLDN14: Claudin 14 Hs.660278 [show with all ESTs]Unigene Representative Sequence: NM_1444926 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000399139(uc002yvk.1) ENST00000399137(uc002yvl.1) ENST00000399135(uc002yvm.1) ENST00000399136(uc002yvn.1) ENST00000342108(uc002yvo.1) ENST00000478313
Clone Products: |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CLDN14 (see all 9) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CLDN14 (see all 5) OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 5): CLDN14 (NM_144492) | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CLDN14 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CLDN14  |
Additional cDNA sequence: AF314090.1 AJ566765.1 AJ566766.1 AY355348.1 AY355349.1 AY358533.1 BC012126.1 3 DOTS entries: DT.91828499 DT.97836433 DT.100736513 23 AceView cDNA sequences: BC012126 AY355349 BM911659 NM_012130 AJ566765 AY358533 AJ566766 AY355348 NM_144492 AW471454 CD624232 AF314090 BQ056804 BV197190 BV198315 BX101474 CD624233 BM559307 BG491506 CD624236 AI655909 CD636896 BG491911 GeneLoc Exon Structure
5/6 Alternative Splicing Database (ASD) splice patterns (SP) for CLDN14 (see all 6) About this scheme
| ExUns: | 1 | ^ | 2a | · | 2b | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | |
| SP1: | |   | - |   | - |   | - |   | |   | - |   | - |   | - |   | |   | |
| SP2: | |   | |   | |   | - |   | |   | - |   | - |   | - |   | |   | |
| SP3: | |   | |   | |   | |   | |   | |   | |   | - |   | |   | |
| SP4: | |   | |   | |   | |   | |   | |   | |   | |   | |   | |
| SP5: | |   | |   | |   | |   | |   | |   | |   | |   | |   |
ECgene alternative splicing isoforms for CLDN14
|
Expression for CLDN14 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| CLDN14 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this imageBioGPS CGAP TAG: AAGTTTGAGA
 About this image See CLDN14 Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for CLDN14
SOURCE GeneReport for Unigene cluster: Hs.660278
UniProtKB/Swiss-Prot: CLD14_HUMAN, O95500Tissue specificity: Liver, kidney. Also found in ear SABiosciences Expression via Pathway-Focused PCR Arrays including CLDN14:
Primer Products: |  | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CLDN14 Browse OriGene validated miRNA SYBR primer pairs
| |  | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat CLDN14 | |  | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CLDN14 | |  | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CLDN14 | In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CLDN14 |
Orthologs for CLDN14 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for CLDN14 gene from 3/11 species (see all 11) About this table
ENSEMBL Gene Tree for CLDN14 (if available) TreeFam Gene Tree for CLDN14 (if available)  |
Paralogs for CLDN14 gene(Paralogs according to
1HomoloGene, 2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68) About This Section
| Paralogs for CLDN14 gene
- CLDN92 CLDN42 CLDN82 CLDN202 CLDN172 CLDN52 CLDN22 CLDN102
- CLDN152 CLDN32 CLDN12 CLDN62 CLDN72 CLDN192
18 SIMAP similar genes for CLDN14 using alignment to 1 protein entry: CLD14_HUMAN:CLDN7 CLDN2 CLDN4 CLDN19 CLDN9 CLDN1 CLDN8 CLDN20 CLDN3 CLDN6 CLDN10 CLDN5 CLDN18 CLDN24 CLDN17 CLDN22 CLDN15 CLDN25
CLDN14 for paralogs About GeneDecksing
|
Genomic Variants for CLDN14 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical significance | Chr 21 pos | Sequence | # | AA Chg | Type | More | # | Allele freq | Pop | Total sample | More |
|---|
HapMap Linkage Disequilibrium report for CLDN14 (37832919 - 37948867 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV): 8 variations for CLDN14 6 CNVs: 90770 7323 103086 79344 73632 79343 2 Indels: 46162 61975 Human Gene Mutation Database (HGMD): CLDN14
Locus Specific Mutation Databases (LSDB): CLDN14
 | SABiosciences Cancer Mutation PCR Assays |
|  | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CLDN14 |
|
Disorders
/ Diseases for CLDN14 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
CLDN14 for disorders About GeneDecksing
OMIM gene information: 605608
OMIM disorders: --
UniProtKB/Swiss-Prot: CLD14_HUMAN, O95500
Defects in CLDN14 are the cause of deafness autosomal recessive type 29 (DFNB29) [MIM:614035]. DFNB29 is aform of sensorineural hearing loss. Sensorineural deafness results from damage to the neural receptors of the innerear, the nerve pathways to the brain, or the area of the brain that receives sound information 6 diseases for CLDN14: About MalaCardsdeafness, autosomal recessive 29 hearing loss nephrolithiasis hepatitis c tonsillitis hepatitis 2 diseases from the University of Copenhagen DISEASES database for CLDN14:Nephrolithiasis Nonsyndromic deafness Human Genome Epidemiology (HuGE) Navigator: CLDN14 (3 documents) Export disorders for CLDN14 gene to outside databases
|
Publications for CLDN14 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for CLDN14 gene, integrated from 9 sources (see all 28): (articles sorted by number of sources associating them with CLDN14) | |  | Utopia: connect your pdf to the dynamic world of online information |
- Mutations in the gene encoding tight junction claudin-14 cause autosomal recessive deafness DFNB29. (PubMed id 11163249)1, 2, 3 Wilcox E.R.... Friedman T.B. (2001)
- Frequencies of gap- and tight-junction mutations in Turkish families with autosomal-recessive non-syndromic hearing loss. (PubMed id 12791041)1, 2, 9 Uyguner O.... Wollnik B. (2003)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. (PubMed id 12975309)1, 2 Clark H.F.... Gray A.M. (2003)
- The DNA sequence of human chromosome 21. (PubMed id 10830953)1, 2 Hattori M....Yaspo M.L. (2000)
- Different mechanisms preclude mutant CLDN14 proteins from forming tight junctions in vitro. (PubMed id 15880785)1, 9 Wattenhofer M....Antonarakis S.E. (2005)
- Palmitoylation of claudins is required for efficient tight-junction localization. (PubMed id 15769849)1, 9 Van Itallie C.M....Anderson J.M. (2005)
- Novel CLDN14 mutations in Pakistani families with auto somal recessive non-syndromic hearing loss. (PubMed id 22246673)1 Lee K....Leal S.M. (2012)
- Mutations in CLDN14 are associated with different hea ring thresholds. (PubMed id 20811388)1 Bashir R....Naz S. (2010)
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PubMed id 20379614)1 Rose J.E....Uhl G.R. (2010)
|
External Searches for CLDN14 gene
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
|
|
Genome Databases showing CLDN14 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing CLDN14 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing CLDN14 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
| Name | Description |
| PharmGKB entry for CLDN14 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for CLDN14 gene: Search GeneIP for patents involving CLDN14
GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products for CLDN14 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory) About This Section
|
 | |
 | |
 |
| | | | OriGene Antibodies for CLDN14 | | OriGene shRNA RFP for CLDN14 | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CLDN14 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CLDN14 | | OriGene Protein Over-expression Lysate for CLDN14 | | Browse OriGene Fluorogenic Cell Assay Kits | | OriGene siRNA for CLDN14 | | OriGene 3'-UTR Clone for CLDN14 | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CLDN14 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CLDN14 | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | OriGene Custom Antibody Services for CLDN14 | | OriGene Custom Protein Services for CLDN14 | | OriGene Custom Immunoassay Development | | |
| |  |
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 |  |  |  | |
| | | Search Tocris compounds for CLDN14 |
| |  |  |  |  | | | | |
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 | | CLDN14 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CLDN14 |
|  |  |  |  | | | ThermoFisher Antibodies for CLDN14 |
| | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CLDN14 |
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