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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

CLDN12 Gene

protein-coding   GIFtS: 56
GCID: GC07P090013

Claudin 12

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Claudin 121 2
claudin-122

External Ids:    HGNC: 20341   Entrez Gene: 90692   Ensembl: ENSG000001572247   OMIM: 6112325   UniProtKB: P567493   

Export aliases for CLDN12 gene to outside databases

Previous GC identifers: GC07P088568 GC07P089630 GC07P089644 GC07P089677 GC07P089871 GC07P084642


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for CLDN12 Gene:
This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight
junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing
freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles
in maintaining cell polarity and signal transductions. This gene is expressed in the inner ear and bladder
epithelium, and it is over-expressed in colorectal carcinomas. This protein and claudin 2 are critical for
vitamin D-dependent Ca2+ absorption between enterocytes. Multiple alternatively spliced transcript variants
encoding the same protein have been found.(provided by RefSeq, Sep 2011)

GeneCards Summary for CLDN12 Gene: 
CLDN12 (claudin 12) is a protein-coding gene. Diseases associated with CLDN12 include endotheliitis, and colorectal cancer, and among its related super-pathways are Cell-cell junction organization and Sertoli-Sertoli Cell Junction Dynamics. GO annotations related to this gene include structural molecule activity and identical protein binding.

UniProtKB/Swiss-Prot: CLD12_HUMAN, P56749
Function: Plays a major role in tight junction-specific obliteration of the intercellular space, through
calcium-independent cell-adhesion activity (By similarity)

Gene Wiki entry for CLDN12 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000007.13  NT_007933.15  NC_018918.2  NT_079595.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the CLDN12 gene promoter:
         STAT5B   ER-alpha   C/EBPbeta   AML1a   AP-1   GATA-1   E47   Max   ZIC2/Zic2   c-Myc   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): CLDN12 promoter sequence
   Search SABiosciences Chromatin IP Primers for CLDN12

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CLDN12


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 7q21   Ensembl cytogenetic band:  7q21.13   HGNC cytogenetic band: 7q21

CLDN12 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CLDN12 gene location

GeneLoc information about chromosome 7         GeneLoc Exon Structure

GeneLoc location for GC07P090013:  view genomic region     (about GC identifiers)

Start:
90,013,035 bp from pter      End:
90,142,716 bp from pter
Size:
129,682 bases      Orientation:
plus strand

1 alternative location:
Chr7+,CRA_TCAG 89,363,457-89,376,077     

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: CLD12_HUMAN, P56749 (See protein sequence)
Recommended Name: Claudin-12  
Size: 244 amino acids; 27110 Da
Subcellular location: Cell junction, tight junction. Cell membrane; Multi-pass membrane protein
Secondary accessions: D6W5Q4 Q7LDZ0

Explore the universe of human proteins at neXtProt for CLDN12: NX_P56749

Explore proteomics data for CLDN12 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_P56749

  • CLDN12 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    CLDN12 Protein Expression
    REFSEQ proteins (3 alternative transcripts): 
    NP_001172001.1  NP_001172002.1  NP_036261.1  

    ENSEMBL proteins: 
     ENSP00000411399   ENSP00000419053   ENSP00000287916   ENSP00000378102   ENSP00000378103  
     ENSP00000391062   ENSP00000443476  
    Reactome Protein details: P56749
    Human Recombinant Protein Products for CLDN12: 
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    Novus Biologicals CLDN12 Protein
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for CLDN12 

    Gene Ontology (GO): 4 cellular component terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005886plasma membrane IEA--
    GO:0005923tight junction ISS--
    GO:0016021integral to membrane IEA--
    GO:0071944cell periphery ----

    CLDN12 for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    HGNC Gene Families: 
    CLDN: Claudins

    2 InterPro protein domains:
     IPR017974 Claudin_CS
     IPR013287 Claudin12

    Graphical View of Domain Structure for InterPro Entry P56749

    ProtoNet protein and cluster: P56749

    1 Blocks protein domain: IPB006187 Claudin family signature

    UniProtKB/Swiss-Prot: CLD12_HUMAN, P56749
    Similarity: Belongs to the claudin family


    CLDN12 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: CLD12_HUMAN, P56749
    Function: Plays a major role in tight junction-specific obliteration of the intercellular space, through
    calcium-independent cell-adhesion activity (By similarity)

         Genatlas biochemistry entry for CLDN12:
    claudin 12,clostridium perfringens enterotoxin receptor,integral membrane protein,claudin family of major
    structural components of tight junction (TJ) strands

         Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005198structural molecule activity IEA--
    GO:0042802identical protein binding ISS--
         
    CLDN12 for ontologies           About GeneDecksing


    Animal Models:
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    SwitchGear 3'UTR luciferase reporter plasmidCLDN12 3' UTR sequence
    Inhib. RNA
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section

    SuperPaths for CLDN12 About                                                                                                See pathways by source

    SuperPathContained pathways About
    1Cell-cell junction organization
    Cell-cell junction organization0.69
    Cell-Cell communication0.64
    Cell junction organization0.69
    Tight junction interactions0.49
    2Sertoli-Sertoli Cell Junction Dynamics
    Sertoli-Sertoli Cell Junction Dynamics0.38
    Epithelial Tight Junctions0.36
    3Integrin Pathway
    Transendothelial Migration of Leukocytes0.38

    Pathways by source                                                                                                                                                                 See SuperPaths
    Show all pathways

    3 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for CLDN12
        Sertoli-Sertoli Cell Junction Dynamics
    Epithelial Tight Junctions
    Transendothelial Migration of Leukocytes

    4        Reactome Pathways for CLDN12
        Tight junction interactions
    Cell junction organization
    Cell-Cell communication
    Cell-cell junction organization



    CLDN12 for pathways           About GeneDecksing

    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CLDN12

    STRING Interaction Network Preview (showing 5 interactants - click image to see 10)

    5/11 Interacting proteins for CLDN12 (P567492, 3 ENSP000002879164) via UniProtKB, MINT, STRING, and/or I2D (see all 11)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    STRN4Q9NRL32, 3MINT-65603 I2D: score=5 
    CLDN14ENSP000003392924STRING: ENSP00000339292
    CLDN15ENSP000003088704STRING: ENSP00000308870
    CLDN17ENSP000002868084STRING: ENSP00000286808
    CLDN18ENSP000001836054STRING: ENSP00000183605
    About this table

    Gene Ontology (GO): 4 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0016338calcium-independent cell-cell adhesion ISS--
    GO:0034329cell junction assembly TAS--
    GO:0045216cell-cell junction organization TAS--
    GO:0070830tight junction assembly TAS--

    CLDN12 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for CLDN12 (CLD12)

    1 HMDB Compound for CLDN12    About this table
    CompoundSynonyms CAS #PubMed Ids
    CalciumCa (see all 2)7440-70-2--

    Search CenterWatch for drugs/clinical trials and news about CLDN12 / CLD12

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
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    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for CLDN12 gene (3 alternative transcripts): 
    NM_001185072.2  NM_001185073.2  NM_012129.4  

    Unigene Cluster for CLDN12:

    Claudin 12
    Hs.731917  [show with all ESTs]
    Unigene Representative Sequence: NM_001185072
    17 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000416322 ENST00000496677 ENST00000287916(uc010leq.3 uc003uks.3 uc003ukr.3)
    ENST00000462636 ENST00000480135 ENST00000495768 ENST00000394604 ENST00000394605(uc003ukp.3 uc003ukq.3)
    ENST00000498033 ENST00000483862 ENST00000498326 ENST00000427904 ENST00000451941
    ENST00000478752 ENST00000485696 ENST00000476475 ENST00000535571
    miRNA
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    hsa-let-7d hsa-miR-15a hsa-miR-503 hsa-miR-500a hsa-miR-1304 hsa-let-7g hsa-miR-424 hsa-let-7a
    SwitchGear 3'UTR luciferase reporter plasmidCLDN12 3' UTR sequence
    Inhib. RNA
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    Additional mRNA sequence: 

    AK312480.1 AL136770.1 BC036754.2 BC068532.1 CR533470.1 

    15 DOTS entries:

    DT.111476  DT.95085341  DT.91889038  DT.104364  DT.121073535  DT.121073583  DT.95227363  DT.91756215 
    DT.91760139  DT.92417965  DT.100023403  DT.102828562  DT.40296735  DT.91645082  DT.95080356 

    24/134 AceView cDNA sequences (see all 134):

    AA360027 BC036754 BM464072 BM128691 BQ129411 BM052919 BX956995 BM982966 
    AA370173 AA720604 AA594409 AI201137 BU676054 AL704668 AI015771 BI602797 
    CD642689 BU679743 AW961191 BG290581 AI590425 AI696647 AI351720 BF382093 

    GeneLoc Exon Structure

    5/8 Alternative Splicing Database (ASD) splice patterns (SP) for CLDN12 (see all 8)    About this scheme

    ExUns: 1a · 1b · 1c · 1d · 1e · 1f ^ 2 ^ 3 ^ 4 ^ 5a · 5b · 5c ^ 6a · 6b · 6c · 6d · 6e
    SP1:                                      -     -                 -     -                                 
    SP2:                                      -     -                       -                                 
    SP3:                                      -     -                 -     -                                 
    SP4:                                      -     -           -     -     -                                 
    SP5:                                      -     -                                                         


    ECgene alternative splicing isoforms for CLDN12

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    CLDN12 expression in normal human tissues (normalized intensities)      CLDN12 embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: GGAGAGAAAA
    CLDN12 Expression
    About this image


    CLDN12 expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/3 selected tissues (see all 3) fully expand
     
     Testis (Reproductive System)
             sperm   
     
     Blood (Hematopoietic System)
             Hematopoietic Stem Cells Hematopoietic Bone Marrow
     
     Oral Cavity (Gastrointestinal Tract)
             saliva   

    See CLDN12 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for CLDN12

    SOURCE GeneReport for Unigene cluster: Hs.731917
        SABiosciences Expression via Pathway-Focused PCR Arrays including CLDN12: 
              Tight Junctions in human mouse rat
              Cell Junction PathwayFinder in human mouse rat

    Primer
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CLDN12

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for CLDN12 gene from 5/10 species (see all 10)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Cldn121 , 5 claudin 121, 5 87.43(n)1
    91.39(a)1
      5 (2.98 cM)5
    649451  NM_001193659.11  NP_001180588.11 
     55051095 
    chicken
    (Gallus gallus)
    Aves CLDN121 claudin 12 73.22(n)
    77.87(a)
      771872  XM_001234157.2  XP_001234158.1 
    lizard
    (Anolis carolinensis)
    Reptilia CLDN126
    Uncharacterized protein
    72(a)
    1 ↔ 1
    6(20418996-20419733)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia Str.74302 Transcribed sequence with weak similarity to protein more 73.94(n)    141998322 
    zebrafish
    (Danio rerio)
    Actinopterygii cldn121 claudin 12 58(n)
    55.16(a)
      81593  NM_131773.1  NP_571848.1 


    ENSEMBL Gene Tree for CLDN12 (if available)
    TreeFam Gene Tree for CLDN12 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
      --

    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/266 SNPs in CLDN12 are shown (see all 266)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 7 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs178673371,2
    C,F,H--89361501(+) CTATGA/TACATC 3 -- us2k17Minor allele frequency- T:0.03NS EA CSA WA 539
    rs1138605861,2
    C,F--89361517(+) CACATT/CAGTAA 3 -- us2k13Minor allele frequency- C:0.08CSA WA 121
    rs1890839401,2
    --89361573(+) GACCTA/GTGTCA 3 -- us2k10--------
    rs1815288051,2
    --89361674(+) CTAACA/GCAGTG 3 -- us2k10--------
    rs78111781,2
    C,F,A,H--89361686(+) CCAAAT/CGGGAA 3 -- us2k115Minor allele frequency- C:0.19NS EA NA WA CSA 791
    rs800836581,2
    C--89361848(+) CCAATT/CATCTA 3 -- us2k11Minor allele frequency- C:0.01EA 120
    rs1468746211,2
    --89361902(+) TTGCTA/GTGCCA 3 -- us2k10--------
    rs77929601,2
    C,F,H--89361904(+) GCTATG/ACCAGA 3 -- us2k112Minor allele frequency- A:0.11NS EA NA WA 962
    rs1862102841,2
    --89361957(+) TAGGGC/TTGTCT 3 -- us2k10--------
    rs115057861,2
    C,F,A,H--89361990(+) TTTTTT/AAAAAT 3 -- us2k15Minor allele frequency- A:0.02NS EA NA 420

    HapMap Linkage Disequilibrium report for CLDN12 (90013035 - 90142716 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for CLDN12:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv24241CNV Loss19812545
    nsv888709CNV Gain21882294

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    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 611232    OMIM disorders: --

    2 diseases for CLDN12:    About MalaCards
    endotheliitis    colorectal cancer


    CLDN12 for disorders           About GeneDecksing

    Genetic Association Database (GAD): CLDN12
    Human Genome Epidemiology (HuGE) Navigator: CLDN12 (1 document)

    Export disorders for CLDN12 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for CLDN12 gene, integrated from 9 sources (see all 35):
    (articles sorted by number of sources associating them with CLDN12)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    2. Human chromosome 7: DNA sequence and biology. (PubMed id 12690205)1, 2 Scherer S.W.... Tsui L.-C. (2003)
    3. The DNA sequence of human chromosome 7. (PubMed id 12853948)1, 2 Hillier L.W.... Wilson R.K. (2003)
    4. Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PubMed id 11230166)1, 2 Wiemann S.... Poustka A. (2001)
    5. Toward an understanding of the protein interaction net work of the human liver. (PubMed id 21988832)1 Wang J....Yang X. (2011)
    6. Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
    7. Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
    8. Global identification of modular cullin-RING ligase su bstrates. (PubMed id 21963094)1 Emanuele M.J....Elledge S.J. (2011)
    9. Claudins in human cancer: a review. (PubMed id 19924644)1 Ouban A. and Ahmed A.A. (2010)
    10. Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. (PubMed id 19690332)2 Mayya V.... Han D.K. (2009)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 9069 HGNC: 2034 AceView: CLDN12 Ensembl:ENSG00000157224 euGenes: HUgn9069
    ECgene: CLDN12 H-InvDB: CLDN12

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for CLDN12 Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for CLDN12 gene:
    Search GeneIP for patents involving CLDN12

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 3 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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