CLDN12 Gene
protein-coding GIFtS: 55
GCID: GC07P090013
|
|
claudin 12
| |
Aliases for CLDN12 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb) About This Section
|
| Aliases |
|---|
| Claudin 121 2 | | Claudin-121 |
Export aliases for CLDN12 gene to outside databasesPrevious GC identifers: GC07P088568 GC07P089630 GC07P089644 GC07P089677 GC07P089871 GC07P084642 |
Summaries for CLDN12 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
| Entrez Gene summary for CLDN12: This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tightjunction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freelythrough the paracellular space between epithelial or endothelial cell sheets, and also play critical roles inmaintaining cell polarity and signal transductions. This gene is expressed in the inner ear and bladder epithelium,and it is over-expressed in colorectal carcinomas. This protein and claudin 2 are critical for vitamin D-dependentCa2+ absorption between enterocytes. Multiple alternatively spliced transcript variants encoding the same protein havebeen found.(provided by RefSeq, Sep 2011) UniProtKB/Swiss-Prot: CLD12_HUMAN, P56749Function: Plays a major role in tight junction-specific obliteration of the intercellular space, throughcalcium-independent cell-adhesion activity (By similarity) Gene Wiki entry for CLDN12
|
Genomic Views for CLDN12 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics) About This Section
| RefSeq DNA sequence:- NC_000007.13 NC_018918.1 NT_007933.15 NT_079595.2
Regulatory elements: SABiosciences Regulatory transcription factor binding sites in the CLDN12 gene promoter: STAT5B ER-alpha C/EBPbeta AML1a AP-1 GATA-1 E47 Max ZIC2/Zic2 c-Myc Other transcription factors
Search SABiosciences Chromatin IP Primers for CLDN12
Epigenetics:
|  | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CLDN12 |
Genomic Location: Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 7q21 Ensembl cytogenetic band: 7q21.13 HGNC cytogenetic band: 7q21CLDN12 Gene in genomic location: bands according to Ensembl, locations according to
(and/or Entrez Gene and/or Ensembl if different)

GeneLoc information about chromosome 7 GeneLoc Exon Structure GeneLoc location for GC07P090013: view genomic region
(about GC identifiers)
Start:
|
90,013,035 bp from pter |
End:
|
90,142,716 bp from pter |
Size:
|
129,682 bases |
Orientation:
|
plus strand |
1 alternative location:
| Chr7+,CRA_TCAG 89,363,521-89,376,077 |
|
Proteins for CLDN12 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
| UniProtKB/Swiss-Prot: CLD12_HUMAN, P56749 (See
protein sequence)Recommended Name: Claudin-12 Size: 244 amino acids; 27110 Da
Subcellular location: Cell junction, tight junction. Cell membrane; Multi-pass membrane protein
Secondary accessions: D6W5Q4 Q7LDZ0Explore the universe of human proteins at neXtProt for CLDN12: NX_P56749
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_P56749 CLDN12 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (3 alternative transcripts):
NP_001172001.1 NP_001172002.1 NP_036261.1 ENSEMBL proteins: ENSP00000394444 ENSP00000411399 ENSP00000419053 ENSP00000287916 ENSP00000378102 ENSP00000378103 ENSP00000391062 ENSP00000443476 Reactome Protein details: P56749 Human Recombinant Protein Products:
Gene Ontology (GO): 3 cellular component terms (GO ID links to tree view): About this table
CLDN12 for ontologies About GeneDecksing
CLDN12 Antibody Products: Assay Products for CLDN12: |
Protein
Domains / Families for CLDN12 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
CLDN12 for domains About GeneDecksing
2 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry P56749ProtoNet protein and cluster: P56749 1 Blocks protein family: IPB006187 Claudin family signature
UniProtKB/Swiss-Prot: CLD12_HUMAN, P56749Similarity: Belongs to the claudin family |
Function for CLDN12 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
| Function Summary: UniProtKB/Swiss-Prot: CLD12_HUMAN, P56749Function: Plays a major role in tight junction-specific obliteration of the intercellular space, throughcalcium-independent cell-adhesion activity (By similarity) Genatlas biochemistry entry for CLDN12:claudin 12,clostridium perfringens enterotoxin receptor,integral membrane protein,claudin family of major structuralcomponents of tight junction (TJ) strands
Clone Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CLDN12 (see all 6) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CLDN12 OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 3): CLDN12 (NM_001185072) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CLDN12 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CLDN12  |
In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CLDN12 |
Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005198 | structural molecule activity |
IEA | -- | | GO:0042802 | identical protein binding |
ISS | -- |
CLDN12 for ontologies About GeneDecksing
|
Pathways & Interactions for CLDN12 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
| Unified GeneCards pathways  About this table  See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Cell-cell junction organization | | | 2 | Sertoli-Sertoli Cell Junction Dynamics | | | 3 | Integrin Pathway | |
Pathway sources See GeneCards unified pathways Show all pathways
3 Downloadable PowerPoint Slides of QIAGEN Pathway Central Maps for CLDN12 4
Reactome Pathways for CLDN12
CLDN12 for pathways About GeneDecksing
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CLDN12
STRING Interaction
Network Preview (showing 5 interactants - click image to see 10)
 5/11 Interacting proteins for CLDN12 (P567492, 3 ENSP000002879164) via UniProtKB, MINT, STRING, and/or I2D (see all 11)About this table
Gene Ontology (GO): 4 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0016338 | calcium-independent cell-cell adhesion |
ISS | -- | | GO:0034329 | cell junction assembly |
TAS | -- | | GO:0045216 | cell-cell junction organization |
TAS | -- | | GO:0070830 | tight junction assembly |
TAS | -- |
CLDN12 for ontologies About GeneDecksing
|
Drugs & Compounds for CLDN12 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
Browse Tocris compounds for CLDN12
1 HMDB Compound for CLDN12 About this table Search CenterWatch for drugs/clinical trials and news about CLDN12 / CLD12 
|
Transcripts for CLDN12 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank, RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
) About This Section
| REFSEQ mRNAs for CLDN12 gene (3 alternative transcripts): NM_001185072.2 NM_001185073.2 NM_012129.4 Unigene Cluster for CLDN12: Claudin 12 Hs.731917 [show with all ESTs]Unigene Representative Sequence: NM_00118507218 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000422604 ENST00000416322 ENST00000496677 ENST00000287916(uc010leq.3 uc003uks.3 uc003ukr.3) ENST00000462636 ENST00000480135 ENST00000495768 ENST00000394604 ENST00000498033 ENST00000483862 ENST00000498326 ENST00000394605(uc003ukp.3 uc003ukq.3) ENST00000427904 ENST00000451941 ENST00000478752 ENST00000485696 ENST00000476475 ENST00000535571
Clone Products: |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CLDN12 (see all 6) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CLDN12 OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 3): CLDN12 (NM_001185072) | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CLDN12 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CLDN12  |
Additional cDNA sequence: AK312480.1 AL136770.1 BC036754.2 BC068532.1 CR533470.1 15 DOTS entries: DT.111476 DT.95085341 DT.91889038 DT.104364 DT.121073535 DT.121073583 DT.95227363 DT.91756215 DT.91760139 DT.92417965 DT.100023403 DT.102828562 DT.40296735 DT.91645082 DT.95080356 24/134 AceView cDNA sequences (see all 134): AA594409 BX956995 BC036754 AI201137 BM982966 BM128691 AA370173 AA360027 BM052919 BM464072 AA720604 BQ129411 BM052665 BQ007872 AI590425 CD652544 CK823625 AA126720 CB985359 AL136770 AI500090 AW172655 N77782 AA424183 GeneLoc Exon Structure
5/8 Alternative Splicing Database (ASD) splice patterns (SP) for CLDN12 (see all 8) About this scheme
| ExUns: | 1a | · | 1b | · | 1c | · | 1d | · | 1e | · | 1f | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5a | · | 5b | · | 5c | ^ | 6a | · | 6b | · | 6c | · | 6d | · | 6e | |
| SP1: | |   | |   | |   | |   | |   | |   | - |   | - |   | |   | |   | - |   | - |   | |   | |   | |   | |   | |   | |
| SP2: | |   | |   | |   | |   | |   | |   | - |   | - |   | |   | |   | |   | - |   | |   | |   | |   | |   | |   | |
| SP3: | |   | |   | |   | |   | |   | |   | - |   | - |   | |   | |   | - |   | - |   | |   | |   | |   | |   | |   | |
| SP4: | |   | |   | |   | |   | |   | |   | - |   | - |   | |   | - |   | - |   | - |   | |   | |   | |   | |   | |   | |
| SP5: | |   | |   | |   | |   | |   | |   | - |   | - |   | |   | |   | |   | |   | |   | |   | |   | |   | |   |
ECgene alternative splicing isoforms for CLDN12
|
Expression for CLDN12 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| CLDN12 expression in normal human tissues (normalized intensities) See probesets specificity/sensitivity at GeneAnnot About this imageBioGPS CGAP TAG: GGAGAGAAAA
About this image See CLDN12 Protein Expression from SPIRE MOPED and PaxDB Genevestigator expression for CLDN12
SOURCE GeneReport for Unigene cluster: Hs.731917 SABiosciences Expression via Pathway-Focused PCR Arrays including CLDN12:
Primer Products: |  | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CLDN12 Browse OriGene validated miRNA SYBR primer pairs
| |  | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat CLDN12 | |  | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CLDN12 | |  | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CLDN12 | In Situ Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CLDN12 |
Orthologs for CLDN12 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of chordates.
Orthologs for CLDN12 gene from 5/10 species (see all 10) About this table
ENSEMBL Gene Tree for CLDN12 (if available) TreeFam Gene Tree for CLDN12 (if available)  |
Paralogs for CLDN12 gene(Paralogs according to
1HomoloGene, 2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68) About This Section
| -- |
Genomic Variants for CLDN12 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical significance | Chr 7 pos | Sequence | # | AA Chg | Type | More | # | Allele freq | Pop | Total sample | More |
|---|
HapMap Linkage Disequilibrium report for CLDN12 (90013035 - 90142716 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions) Database of Genomic Variants (DGV): 1 variation for CLDN12 1 CNV: 69996  | SABiosciences Cancer Mutation PCR Assays |
|  | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CLDN12 |
|
Disorders
/ Diseases for CLDN12 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
CLDN12 for disorders About GeneDecksing
OMIM gene information: 611232
OMIM disorders: --
2 diseases for CLDN12: About MalaCardscarcinoma colorectal cancer Human Genome Epidemiology (HuGE) Navigator: CLDN12 (1 document) Export disorders for CLDN12 gene to outside databases
|
Publications for CLDN12 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for CLDN12 gene, integrated from 9 sources (see all 32): (articles sorted by number of sources associating them with CLDN12) | |  | Utopia: connect your pdf to the dynamic world of online information |
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- Human chromosome 7: DNA sequence and biology. (PubMed id 12690205)1, 2 Scherer S.W.... Tsui L.-C. (2003)
- The DNA sequence of human chromosome 7. (PubMed id 12853948)1, 2 Hillier L.W.... Wilson R.K. (2003)
- Towards a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs. (PubMed id 11230166)1, 2 Wiemann S.... Poustka A. (2001)
- Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
- Systematic and quantitative assessment of the ubiquiti n-modified proteome. (PubMed id 21906983)1 Kim W....Gygi S.P. (2011)
- Claudins in human cancer: a review. (PubMed id 19924644)1 Ouban A. and Ahmed A.A. (2010)
- Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions. (PubMed id 19690332)2 Mayya V.... Han D.K. (2009)
- The claudins. (PubMed id 19706201)1 Lal-Nag M. and Morin P.J. (2009)
- Ubiquitin-mediated proteolysis of HuR by heat shock. (PubMed id 19322201)1 Abdelmohsen K....Gorospe M. (2009)
|
External Searches for CLDN12 gene
(in PubMed,
OMIM, and NCBI Bookshelf) About This Section
|
|
Genome Databases showing CLDN12 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing CLDN12 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing CLDN12 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL, Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot) About This Section
|
| Name | Description |
| PharmGKB entry for CLDN12 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for CLDN12 gene: Search GeneIP for patents involving CLDN12
GeneCards and IP: Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products for CLDN12 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences), In Situ Hybridization Assays from Advanced Cell Diagnostics About This Section
|
 | |
 | |
 |
| | | | Browse OriGene Antibodies | | OriGene shRNA RFP for CLDN12 | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CLDN12 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CLDN12 | | OriGene Protein Over-expression Lysate for CLDN12 | | Browse OriGene Fluorogenic Cell Assay Kits | | OriGene siRNA for CLDN12 | | OriGene 3'-UTR Clone for CLDN12 | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CLDN12 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CLDN12 | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | OriGene Custom Antibody Services for CLDN12 | | OriGene Custom Protein Services for CLDN12 | | OriGene Custom Immunoassay Development | | |
| |  |
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| | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat CLDN12 | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CLDN12 | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CLDN12 | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CLDN12 | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CLDN12 | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CLDN12 |
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| | | Search Tocris compounds for CLDN12 |
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 | | CLDN12 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CLDN12 |
|  |  |  | | | ThermoFisher Antibodies for CLDN12 |
| | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CLDN12 |
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