Aliases for CLCA3P Gene
External Ids for CLCA3P Gene
Previous Symbols for CLCA3P Gene
This gene is a transcribed pseudogene belonging to the calcium sensitive chloride conductance protein family. To date, all members of this gene family map to the same site on chromosome 1p31-p22 and share high degrees of homology in size, sequence and predicted structure, but differ significantly in their tissue distributions. This gene contains several nonsense codons compared to other family members that render the transcript a candidate for nonsense-mediated mRNA decay (NMD). Therefore, this gene is unlikely to be protein-coding. [provided by RefSeq, Jan 2009]
GeneCards Summary for CLCA3P Gene
CLCA3P (Chloride Channel Accessory 3, Pseudogene) is a Pseudogene. Among its related pathways are Activation of cAMP-Dependent PKA and Activation of cAMP-Dependent PKA. GO annotations related to this gene include transporter activity and chloride channel activity.
Chloride channels are a family of anion-selective channels involved in a diverse range of biological processes including the regulation of the excitability of neurons, skeletal, cardiac and smooth muscle, cell volume regulation, transepithelial salt transport, the acidification of intra- and extracellular compartments. Ca2+-activated chloride channels (CaCCs) are widely expressed in both excitable and non-excitable cells, are activated by intracellular Ca2+, and modulated by CaMKII and calcineurin.