CLC Gene
protein-coding GIFtS: 56
GCID: GC19M040221
|
|
Charcot-Leyden crystal protein
| |
Aliases
for CLC gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Charcot-Leyden Crystal Protein1 2 3 | | LGALS10A2 | | LGALS101 2 | | Eosinophil Lysophospholipase2 | | LPPL_HUMAN1 2 | | Galectin 102 | | Lysolecithin Acylhydrolase2 3 | | Galectin-103 | | Gal-102 3 | | EC 3.1.1.53 | | MGC1496591 | | Galectin-103 | | GAL102 | | |
Export aliases for CLC gene to outside databasesPrevious GC identifers: GC19M040862 GC19M040613 GC19M044897 GC19M044913 GC19M036668 |
Summaries
for CLC gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for CLC:
Lysophospholipases are enzymes that act on biological membranes to regulate the multifunctional lysophospholipids. Theprotein encoded by this gene is a lysophospholipase expressed in eosinophils and basophils. It hydrolyzeslysophosphatidylcholine to glycerophosphocholine and a free fatty acid. This protein may possess carbohydrate orIgE-binding activities. It is both structurally and functionally related to the galectin family of beta-galactosidebinding proteins. It may be associated with inflammation and some myeloid leukemias. (provided by RefSeq, Jul 2008)
UniProtKB/Swiss-Prot: LPPL_HUMAN, Q05315Function: May have both lysophospholipase and carbohydrate-binding activities
Gene Wiki entry for CLC
|
Genomic Views
for CLC gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000019.9 NC_018930.1 NT_011109.16
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the CLC gene promoter:
FOXI1 HFH-3 p53 HFH-1 STAT3 FOXL1
Other transcription factors
Search SABiosciences Chromatin IP Primers for CLC
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CLC |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 19q13.1 Ensembl cytogenetic band: 19q13.2 HGNC cytogenetic band: 19q13.1CLC Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 19 GeneLoc Exon Structure GeneLoc location for GC19M040221: view genomic region
(about GC identifiers)
Start:
|
40,221,895 bp from pter |
End:
|
40,228,668 bp from pter |
Size:
|
6,774 bases |
Orientation:
|
minus strand |
|
Proteins
for CLC gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: LPPL_HUMAN, Q05315 (See
protein sequence)Recommended Name: Eosinophil lysophospholipase Size: 142 amino acids; 16453 Da
Subcellular location: Cytoplasmic granule. Note=Localized in granules from where it may be secreted or transported toother locations in the cell
Miscellaneous: Forms hexagonal bipyramidal crystals, known as Charcot-Leyden crystals, in tissues and secretions fromsites of eosinophil-associated inflammation and some myeloid leukemias
4 PDB 3D structures from  and Proteopedia  for CLC:1G86 (3D)
1HDK (3D)
1LCL (3D)
1QKQ (3D)
Secondary accessions: Q0VDE3Explore the universe of human proteins at neXtProt for CLC: NX_Q05315
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q05315
CLC Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_001819.2
ENSEMBL proteins: ENSP00000221804
Human Recombinant Protein Products for CLC:
CLC Antibody Products:
Assay Products for CLC: |
Protein
Domains /
Families
for CLC gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
CLC for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q05315ProtoNet protein and cluster: Q05315 1 Blocks protein family: IPB001079 Galectin
UniProtKB/Swiss-Prot: LPPL_HUMAN, Q05315Similarity: Contains 1 galectin domain |
Function
for CLC gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Molecular Function:
UniProtKB/Swiss-Prot Summary: LPPL_HUMAN, Q05315Function: May have both lysophospholipase and carbohydrate-binding activitiesCatalytic activity: 2-lysophosphatidylcholine + H(2)O = glycerophosphocholine + a carboxylate Genatlas biochemistry entry for CLC:Charcot-Leyden crystal protein,eosinophil lysophospholipase,also expressed in basophil,galectin family ofgalactoride-beta binding protein
Enzyme Number (IUBMB): EC 3.1.1.51
Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0004091 | carboxylesterase activity |
IEA | -- | | GO:0004622 | lysophospholipase activity |
IEA | -- | | GO:0030246 | carbohydrate binding |
IEA | -- |
CLC for ontologies About GeneDecksing
Phenotypes:
1 GenomeRNAi human phenotype for CLC:
Animal Models:
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CLC
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CLC
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector: CLC (NM_001828) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CLC | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CLC |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CLC |
|
Pathways & Interactions
for CLC gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for CLC
Gene Ontology (GO): 2 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0007275 | multicellular organismal development |
TAS | 8400237 | | GO:0016042 | lipid catabolic process |
IEA | -- |
CLC for ontologies About GeneDecksing
|
Drugs & Compounds
for CLC gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
CLC for compounds About GeneDecksing
 Browse Tocris compounds for CLC
10/1003 HMDB Compounds for CLC (see all 1003) About this table
3 DrugBank Compounds for CLC About this table
2 Novoseek chemical compound relationships for CLC gene About this table
| Compound |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| chloride |
49.1 |
1 |
10932070 (1) |
| mannose |
44.7 |
3 |
10529229 (2), 11834744 (1) |
Search CenterWatch for drugs/clinical trials and news about CLC / LPPL
|
Transcripts
for CLC gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for CLC gene: NM_001828.5 Unigene Cluster for CLC: Charcot-Leyden crystal protein Hs.889 [show with all ESTs]Unigene Representative Sequence: BU1991331 Ensembl transcript including schematic representation, and UCSC links where relevant: ENST00000221804(uc002omh.3)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CLC
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CLC
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: CLC (NM_001828) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CLC | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CLC |
Additional cDNA sequence: BC119711.1 BC119712.1 FJ613334.1 FJ613335.1 L01664.1 3 DOTS entries: DT.410840 DT.91703965 DT.95364234 24/56 AceView cDNA sequences (see all 56): NM_001828 AW292557 AV715398 AV716973 AV715152 BU198603 AV714443 AV714984 AV714675 AV715261 AV715923 BU198123 BU198769 AV712928 BU616069 L01664 BU198323 AV757393 AV717851 AV762486 AV713086 R09220 AV713515 AI066757
GeneLoc Exon Structure
|
Expression
for CLC gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| CLC expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: ATCTTTTCTC
About this image
See CLC Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for CLC
SOURCE GeneReport for Unigene cluster: Hs.889
UniProtKB/Swiss-Prot: LPPL_HUMAN, Q05315Tissue specificity: Expressed exclusively by eosinophils and basophils. Not detected in monocytes and neutrophils
SABiosciences Expression via Pathway-Focused PCR Arrays including CLC: | Growth Factors in human mouse rat | | Inflammatory Response & Autoimmunity 384HT in human mouse rat | | Allergy & Asthma in human mouse rat |
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CLC
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse / rat CLC | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CLC | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CLC | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CLC |
Orthologs
for CLC gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of human and mouse.
Orthologs for CLC gene from 1/3 species (see all 3) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
mouse
(Mus musculus) |
Mammalia |
Clc5 |
Charcot-Leyden crystal protein |
-- |
|
- |
ENSEMBL Gene Tree for CLC (if available)
TreeFam Gene Tree for CLC (if available) |
Paralogs
for CLC gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for CLC gene
- LGALS162 LGALS142 LGALS132
12 SIMAP similar genes for CLC using alignment to 1 protein entry: LPPL_HUMAN:LGALS10A LOC400696 LGALS17A LGALS13 LGALS16 LGALS14
LGALS9C LGALS9 LGALS9B LGALS8 LGALS7 LGALS7B
CLC for paralogs About GeneDecksing
2 Pseudogenes.org Pseudogenes for CLC
PGOHUM00000234687 PGOHUM00000234695
|
Genomic Variants
for CLC gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 19 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for CLC (40221895 - 40228668 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 2 variations for CLC
2 CNVs: 32253 4079 | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CLC |
|
Disorders
/ Diseases
for CLC gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database, Novoseek,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
CLC for disorders About GeneDecksing
OMIM gene information: 153310
OMIM disorders: --
19  diseases for CLC: About MalaCardsmyeloid leukemia leukemia allergic rhinitis eosinophilic pneumonia
bartter disease cystic fibrosis hypereosinophilic syndrome rhinitis
acute myeloid leukemia osteopetrosis bronchiolitis nephrolithiasis
celiac disease keratoconus fibrosis hepatitis b
hepatitis pneumonia papillary epithelial neoplasm
1 disease from the University of Copenhagen DISEASES database for CLC:Eosinophilic pneumonia 4 Novoseek disease relationships for CLC gene About this table
| Disease |
-log (P-Val) |
Hits |
PubMed IDs for Articles with Shared Sentences (# sentences) |
| allergic rhinitis |
44.4 |
3 |
19650845 (3) |
| cystic fibrosis |
37.3 |
3 |
19274342 (1), 9295337 (1) |
| allergy |
25.9 |
2 |
16457599 (1) |
| inflammation |
5.96 |
1 |
10529229 (1) |
Human Genome Epidemiology (HuGE) Navigator: CLC (11 documents)
Export disorders for CLC gene to outside databases
|
Publications
for CLC gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for CLC gene, integrated from 9 sources (see all 50):
(articles sorted by number of sources associating them with CLC) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Localization of the human eosinophil Charcot-Leyden crystal protein (lysophospholipase) gene (CLC) to chromosome 19 and the human ribonuclease 2 (eosinophil-derived neurotoxin) and ribonuclease 3 (eosinophil cationic protein) genes (RNS2 and RNS3) to chromosome 14. (PubMed id 1577491)1, 2, 3, 9 Mastrianni D.M.... Ackerman S.J. (1992)
- Selective recognition of mannose by the human eosinophil Charcot- Leyden crystal protein (galectin-10): a crystallographic study at 1.8 A resolution. (PubMed id 10529229)1, 2, 9 Swaminathan G.J....Acharya K.R. (1999)
- The genomic structure of the human Charcot-Leyden crystal protein gene is analogous to those of the galectin genes. (PubMed id 9119387)1, 2, 9 Dyer K.D.... Rosenberg H.F. (1997)
- Comparative proteomics of nasal fluid in seasonal allergic rhinitis. (PubMed id 16457599)1, 2, 9 Ghafouri B.... Lindahl M. (2006)
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
- The DNA sequence and biology of human chromosome 19. (PubMed id 15057824)1, 2 Grimwood J.... Lucas S.M. (2004)
- Crystal structure of human Charcot-Leyden crystal protein, an eosinophil lysophospholipase, identifies it as a new member of the carbohydrate-binding family of galectins. (PubMed id 8747464)1, 2 Leonidas D.D....Acharya K.R. (1995)
- Molecular cloning and characterization of human eosinophil Charcot- Leyden crystal protein (lysophospholipase). Similarities to IgE binding proteins and the S-type animal lectin superfamily. (PubMed id 8419478)1, 2 Ackerman S.J....Tenen D.G. (1993)
- Human CD4+CD25+ regulatory T cells: proteome analysis identifies galectin-10 as a novel marker essential for their anergy and suppressive function. (PubMed id 17502455)1, 9 Kubach J....Jonuleit H. (2007)
- CLC- a novel susceptibility gene for allergic rhiniti s? (PubMed id 19650845)1, 9 Bryborn M....Cardell L.O. (2010)
|
External Searches for CLC gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing CLC gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing CLC gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing CLC gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for CLC | Pharmacogenomics, SNPs, Pathways | | ATLAS Chromosomes in Cancer entry for CLC | Genetics and Cytogenetics in Oncology and Haematology | | Functional Glycomics Gateway - Glycan Binding | http://www.functionalglycomics.org/glycomics/GBPServlet?&operationType=view&cbpId=cbp_hum_Stlect_277 |
|
| | |
About This Section
| Patent Information for CLC gene:
Search GeneIP for patents involving CLC
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for CLC gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
 | |
 | |
 |
| | |  | Browse OriGene Antibodies | | OriGene shRNA RFP for CLC | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CLC | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CLC | | | OriGene Protein Over-expression Lysate for CLC | | Browse OriGene Fluorogenic Cell Assay Kits | | | OriGene siRNA for CLC | | OriGene 3'-UTR Clone for CLC | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CLC | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CLC | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | OriGene Purified Protein for CLC | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for CLC | | OriGene Custom Protein Services for CLC | | | OriGene Custom Immunoassay Development | | |
| |
 |
 |
| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat CLC | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CLC | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CLC | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CLC | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CLC | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CLC |
| |
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| |  |  |  |  | | | | | | Recombinant Protein for CLC |
|
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 |
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| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CLC |
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|
