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Category Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21

GIFtS
-

CKMT1B Gene

protein-coding GIFtS: 57
GCID: GC15P043885

creatine kinase, mitochondrial 1B

(Previous names: creatine kinase, mitochondrial 1 (ubiquitous) )
(Previous symbols: CKMT, CKMT1)

Explore 11 diseases affiliated with
CKMT1B via

MalaCards

our new
Human Malady Compendium

(According to ¹HGNC, ²Entrez Gene,
³UniProtKB/Swiss-Prot, ⁴UniProtKB/TrEMBL, ⁵OMIM, ⁶GeneLoc, ⁷Ensembl, ⁸DME, ⁹miRBase, and/or ¹⁰fRNAdb)
About This Section

Aliases
Creatine Kinase, Mitochondrial 1B¹ ²		U-MtCK² ³
CKMT¹ ² ³		EC 2.7.3.2³ ⁸
CKMT1¹ ² ⁵		Creatine Kinase U-Type, Mitochondrial²
UMTCK¹ ²		Mia-CK³
Creatine Kinase, Mitochondrial 1 (Ubiquitous)¹ ²		Mia-CK³
Acidic-Type Mitochondrial Creatine Kinase² ³		EC 2.7.3⁸
Ubiquitous Mitochondrial Creatine Kinase² ³

External Ids:	HGNC: 1995¹	Entrez Gene: 1159²	Ensembl: ENSG00000237289⁷	OMIM: 123290⁵	UniProtKB: P12532³

Export aliases for CKMT1B gene to outside databases

Previous GC identifers: GC15P041674 GC15P020720

(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for CKMT1B:

Mitochondrial creatine (MtCK) kinase is responsible for the transfer of high energy phosphate from mitochondria to the

cytosolic carrier, creatine. It belongs to the creatine kinase isoenzyme family. It exists as two isoenzymes,

sarcomeric MtCK and ubiquitous MtCK, encoded by separate genes. Mitochondrial creatine kinase occurs in two different

oligomeric forms: dimers and octamers, in contrast to the exclusively dimeric cytosolic creatine kinase isoenzymes.

Many malignant cancers with poor prognosis have shown overexpression of ubiquitous mitochondrial creatine kinase; this

may be related to high energy turnover and failure to eliminate cancer cells via apoptosis. Ubiquitous mitochondrial

creatine kinase has 80% homology with the coding exons of sarcomeric mitochondrial creatine kinase. Two genes located

near each other on chromosome 15 have been identified which encode identical mitochondrial creatine kinase proteins.

(provided by RefSeq, Jul 2008)

UniProtKB/Swiss-Prot: KCRU_HUMAN, P12532

Function: Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate).

Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy

demands, such as skeletal muscle, heart, brain and spermatozoa

Gene Wiki entry for CKMT1B

(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section

RefSeq DNA sequence:

NC_018926.1 NC_000015.9 NT_010194.17

Regulatory elements:

SABiosciences Regulatory transcription factor binding sites in the CKMT1B gene promoter:
AP-1 ATF-2 c-Jun
Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 3): CKMT1B promoter sequence

Search SABiosciences Chromatin IP Primers for CKMT1B

Epigenetics:

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CKMT1B

Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 15q15 Ensembl cytogenetic band: 15q15.3 HGNC cytogenetic band: 15q15

CKMT1B Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CKMT1B gene location

GeneLoc information about chromosome 15 GeneLoc Exon Structure

GeneLoc location for GC15P043885: view genomic region (about GC identifiers)

Start:	43,885,252 bp from pter	End:	43,891,604 bp from pter
Size:	6,353 bases	Orientation:	plus strand

(According to ¹UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to ²PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: KCRU_HUMAN, P12532 (See protein sequence)

Recommended Name: Creatine kinase U-type, mitochondrial precursor

Size: 417 amino acids; 47037 Da

Subunit: Exists as an octamer composed of four MTCK homodimers

Subcellular location: Mitochondrion inner membrane; Peripheral membrane protein; Intermembrane side

Miscellaneous: Mitochondrial creatine kinase binds cardiolipin

1 PDB 3D structure from and Proteopedia for CKMT1B:

1QK1 (3D)

Secondary accessions: B4DIT8 B7ZA09 Q0VAM3 Q32NF6 Q53FC4

Alternative splicing: 2 isoforms: P12532-1 P12532-2

Explore the universe of human proteins at neXtProt for CKMT1B: NX_P12532

Post-translational modifications:

View modification sites using PhosphoSitePlus²

View neXtProt modification sites for NX_P12532

4/30 DME Specific Peptides for CKMT1B (P12532) (see all 30)

CPSNLGT

YARLCDK

AGDEETY

FADLFDP

CKMT1B Protein expression data from MOPED and PaxDb: About this image

REFSEQ proteins: NP_066270.1

ENSEMBL proteins:

ENSP00000413999 ENSP00000391990 ENSP00000416467 ENSP00000396707 ENSP00000413255

ENSP00000411531 ENSP00000416717 ENSP00000399467 ENSP00000300283 ENSP00000389267

ENSP00000390428

Reactome Protein details: P12532
Human Recombinant Protein Products for CKMT1B:

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	Uscn Proteins for CKMT1B

Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0005739	mitochondrion	--	--
GO:0005743	mitochondrial inner membrane	--	--

CKMT1B for ontologies About GeneDecksing

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(According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
About This Section

CKMT1B for domains About GeneDecksing

5 InterPro domains/families:

IPR000749 ATP-guanido_PTrfase

IPR014746 Gln_synth/guanido_kin_cat_dom

IPR022413 ATP-guanido_PTrfase_N

IPR022415 ATP-guanido_PTrfase_AS

IPR022414 ATP-guanido_PTrfase_cat

Graphical View of Domain Structure for InterPro Entry P12532

ProtoNet protein and cluster: P12532

1 Blocks protein family: IPB000749 ATP:guanido phosphotransferase

UniProtKB/Swiss-Prot: KCRU_HUMAN, P12532

Similarity: Belongs to the ATP:guanido phosphotransferase family

Similarity: Contains 1 phosphagen kinase C-terminal domain

Similarity: Contains 1 phosphagen kinase N-terminal domain

(According to ¹UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or ²DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory,
bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, Sirion Biotech, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, Sirion Biotech, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
About This Section

Molecular Function:

UniProtKB/Swiss-Prot Summary: KCRU_HUMAN, P12532

Function: Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate).

Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy

demands, such as skeletal muscle, heart, brain and spermatozoa

Catalytic activity: ATP + creatine = ADP + phosphocreatine

Enzyme Numbers (IUBMB): EC 2.7.3.2¹ ² EC 2.7.3²

Gene Ontology (GO): 3 molecular function terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0004111	creatine kinase activity	--	--
GO:0005524	ATP binding	--	--
GO:0016301	kinase activity	--	--

CKMT1B for ontologies About GeneDecksing

Phenotypes:
8 MGI mutant phenotypes (inferred from 1 allele) (MGI details for Ckmt1):

behavior/neurological	digestive/alimentary	growth/size	hearing/vestibular/ear	homeostasis/metabolism
integument	nervous system	reproductive system

CKMT1B for phenotypes About GeneDecksing

Animal Models:
Mouse knock-out Ckmt1^tm2Bew for CKMT1B

inGenious Targeting Laboratory - Customizable classic, inducible, and humanized mouse model solutions for CKMT1B

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In Situ Assay
Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CKMT1B

(Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to ¹UniProtKB, ²MINT, ³I2D, and/or ⁴STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
About This Section

Unified GeneCards pathways About this table

See pathways by source

Super-pathway

contained gene-specific pathways

Arginine and proline metabolism

Arginine and proline metabolism

1.00

creatine-phosphate biosynthesis

creatine-phosphate biosynthesis

1.00

Metabolism

Metabolic pathways

0.38

Pathway sources
See GeneCards unified pathways
Show all pathways

1 BioSystems Pathway for CKMT1B

creatine-phosphate biosynthesis

3 Reactome Pathways for CKMT1B

	Creatine metabolism
	Metabolism
	Metabolism of amino acids and derivatives

2 Kegg Pathways (Kegg details for CKMT1B):

	Arginine and proline metabolism
	Metabolic pathways

CKMT1B for pathways About GeneDecksing

Interactions:

Search SABiosciences Gene Network Central^TM Interacting Genes and Proteins Networks for CKMT1B

STRING Interaction Network Preview (showing 5 interactants - click image to see 11)

5/49 Interacting proteins for CKMT1B (P12532^{2, 3} ENSP00000300283⁴) via UniProtKB, MINT, STRING, and/or I2D (see all 49)

Interactant		Interaction Details
GeneCard	External ID(s)	Interaction Details
CALM1	P62158³	I2D: score=1
CALM2	P62158³	I2D: score=1
CALM3	P62158³	I2D: score=1
SLC25A5	P05141²^,³, ENSP00000360671⁴	MINT-4054731 I2D: score=1 STRING: ENSP00000360671
VDAC1	P21796²^,³, ENSP00000265333⁴	MINT-4054731 I2D: score=2 STRING: ENSP00000265333

About this table

Gene Ontology (GO): 3 biological process terms (GO ID links to tree view): About this table

GO ID	Qualified GO term	Evidence	PubMed IDs
GO:0006600	creatine metabolic process	--	--
GO:0034641	cellular nitrogen compound metabolic process	--	--
GO:0044281	small molecule metabolic process	--	--

CKMT1B for ontologies About GeneDecksing

(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
About This Section

CKMT1B for compounds About GeneDecksing

Browse Small Molecules at EMD Millipore

Browse drugs & compounds from Enzo Life Sciences

Browse Tocris compounds for CKMT1B
5 Novoseek chemical compound relationships for CKMT1B gene About this table

Compound	-log (P-Val)	Hits	PubMed IDs for Articles with Shared Sentences (# sentences)
cyclocreatine	87.9	1	11745437 (1)
cardiolipin	70.7	1	11768757 (1)
creatinine	68.3	51	11874479 (3), 11745437 (2), 16479256 (2), 20302626 (2) (see all 19)
phosphocreatine	59.7	13	8923416 (3), 12701812 (2)
atp	30.1	4	11154064 (1), 12701812 (1)

Search CenterWatch for drugs/clinical trials and news about CKMT1B / KCRU

(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
RNAi Products from EMD Millipore,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, Sirion Biotech, microRNA from QIAGEN,
Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
About This Section

REFSEQ mRNAs for CKMT1B gene:

NM_020990.3

Unigene Cluster for CKMT1B:

Creatine kinase, mitochondrial 1B

Hs.741420 [show with all ESTs]

Unigene Representative Sequence: AK094322

15 Ensembl transcripts including schematic representations, and UCSC links where relevant:

ENST00000453782 ENST00000437924 ENST00000475589 ENST00000481666 ENST00000449946

ENST00000417289 ENST00000441322 ENST00000495545 ENST00000498538 ENST00000453733

ENST00000437534(uc010udv.1 uc010bdj.3 uc010udy.1) ENST00000428981

ENST00000300283(uc001zsc.3 uc010uds.2) ENST00000450086(uc010udw.1)

ENST00000413657(uc010udt.2 uc010bdi.3 uc010udu.2 uc010udx.2)

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		hsa-miR-924 hsa-miR-4294
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Additional cDNA sequence:

AK094322.1 AK223365.1 AK293685.1 AK293790.1 AK293939.1 AK293961.1 AK294002.1 AK294063.1

AK294735.1 AK294908.1 AK295776.1 AK296271.1 AK296472.1 AK308770.1 AK311698.1 AK316124.1

AK316319.1 BC001926.1 BC006467.1 BC108652.1 BC121001.1 BC121002.1

24/25 DOTS entries (see all 25):

DT.95261994 DT.315670 DT.100813509 DT.97850558 DT.100805678 DT.100813525 DT.100813526 DT.121025287

DT.97833511 DT.40254055 DT.100813514 DT.100813522 DT.121025034 DT.97850542 DT.100813520 DT.121024946

DT.121025328 DT.95262005 DT.95261995 DT.121024827 DT.121025341 DT.121025348 DT.97850540 DT.121025027

24/346 AceView cDNA sequences (see all 346):

BM849357 BE794273 AA324707 CR616544 BU146860 BE184296 BE732596 BP362822

BE903209 BE254441 CA488871 CR597545 BE873170 BE732781 BE794868 BQ061098

BM820892 BU166443 BQ721917 NM_020990 BP347728 D56052 CA488873 CB154641

GeneLoc Exon Structure

(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section

CKMT1B expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: --

About this image

CKMT1B expression in embryonic tissues and stem cells
Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine About this table

1 LifeMap In Vivo Development Anatomical Compartment/Cell

Tissue

Anatomical Compartment

Cell

Category (developmental path)

Eye

Outer Nuclear Layer

Mature Rod Cells

Photoreceptors, Retina

Expression:

Positive

Negative

Selective marker

Experimental details:

Curated

Microarrays

In-situ hybridization

Stem Cell Differentiation: 1 LifeMap Cell

Name

Category

CyT49 (Embryonic Stem Cell)

Early Embryo, Inner Cell Mass

See CKMT1B Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for CKMT1B

SOURCE GeneReport for Unigene cluster: Hs.741420

SABiosciences Custom PCR Arrays for CKMT1B

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In Situ
Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CKMT1B

(Orthologs according to ^1,2HomoloGene (²older version, for species not in ¹newer version), ³euGenes, ⁴SGD , ⁵MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or ⁶Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
About This Section

This gene was present in the common ancestor of animals.

Orthologs for CKMT1B gene from 6/18 species (see all 18) About this table

Organism	Taxonomic classification	Gene	Description	Human Similarity	Orthology Type	Details
chicken (Gallus gallus)	Aves	F1NXR0_CHICK⁶	creatine kinase, mitochondrial 1A	86(a)	1 → many	10(22299084-22307289)
lizard (Anolis carolinensis)	Reptilia	--	--	91(a)	1 → many	GL343759.1(238823-244892)
African clawed frog (Xenopus laevis)	Amphibia	ckmt1-prov²	creatine kinase, mitochondrial 1 (ubiquitous)	77.56(n)		BC045123.1
zebrafish (Danio rerio)	Actinopterygii	ckmt1²	creatine kinase, mitochondrial 1	77.87(n)		321892 BC048050.1
fruit fly (Drosophila melanogaster)	Insecta	CG5144⁶ CG4546⁶ (see all 4)	--	28(a) 23(a) (see all 4)	possible ortholog possible ortholog (see all 4)	3L(9040539-9041824) 3R(11672230-11674158)
worm (Caenorhabditis elegans)	Secernentea	F11G11.13⁶ F44G3.2⁶ (see all 6)	Protein F44G3.2 (see all 6)	38(a) 31(a) (see all 6)	possible ortholog possible ortholog (see all 6)	II(4875066-4875697) V(16103874-16106120)

ENSEMBL Gene Tree for CKMT1B (if available)
TreeFam Gene Tree for CKMT1B (if available)

(Paralogs according to ¹HomoloGene,
²Ensembl, and ³SIMAP, Pseudogenes according to ⁴Pseudogene.org Build 68)
About This Section

Paralogs for CKMT1B gene

CKMT1A¹ ² CKB² CKM² CKMT2²

4 SIMAP similar genes for CKMT1B using alignment to 10 protein entries: KCRU_HUMAN (see all proteins):

CKMT1A CKB CKM CKMT2

CKMT1B for paralogs About GeneDecksing

(SNPs/Variants according to the ¹NCBI SNP Database, ²Ensembl, ³PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section

SNP ID	Valid	Clinical significance	Chr 15 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
Genomic Data					Transcription Related Data				Allele Frequencies
				--	--	--		--	--
rs149230297^1,2	C,F	--	43888677(+)	`GGAGAA/GGGGTG`	2	K R	mis¹		1		NA	4434
rs199826616^1,2	F	--	43888689(+)	`TAACAT/CGAAGA`	2	/T /M	mis¹		1		EU	1323
rs146365795^1,2	C	--	43888744(+)	`GACTAT/CGTAGG`	1	--	int¹		1		EU	1323
rs189827985^1,2		--	43888774(+)	`TAAGGA/TAAACC`	1	--	int¹		0	--	--	--	--
rs77834292^1,2		--	43888852(+)	`CTATCT/CAGGAC`	1	--	int¹		2		CSA WA	120
rs113292887^1,2	F	--	43888877(+)	`AAGGTG/ATAAAC`	1	--	int¹		1		CSA	4
rs183186835^1,2		--	43888907(+)	`AAAACC/TAGGAC`	1	--	int¹		0	--	--	--	--
rs187911665^1,2		--	43888915(+)	`GACATC/GTGGTC`	1	--	int¹		0	--	--	--	--
rs10518820^1,2	C,F,H	--	43888976(+)	`AGGCTG/TTTGAC`	1	--	int¹		23		NS EA NA WA CSA	2195
rs66507262^1,2	C	--	43889122(+)	`ACTCTG/AATATA`	1	--	int¹		1		NA	2

HapMap Linkage Disequilibrium report for CKMT1B (43885252 - 43891604 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 11 variations for CKMT1B
11 CNVs: 87664 30709 66780 35314 1282 3079 35315 32027 66782 7061 3960

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(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
About This Section

CKMT1B for disorders           About GeneDecksing

OMIM gene information: 123290    OMIM disorders: --

11 diseases for CKMT1B:    About MalaCards

creatine phosphokinase chronic obstructive pulmonary disease oral squamous cell carcinoma squamous cell carcinoma

pulmonary disease prostate cancer, progression of prostate cancer prostatitis

sarcoma carcinoma neuronitis

2 diseases from the University of Copenhagen DISEASES database for CKMT1B:

Myocardial infarction Prostate rhabdomyosarcoma

Human Genome Epidemiology (HuGE) Navigator: CKMT1B (1 document)

Export disorders for CKMT1B gene to outside databases

(in PubMed. Associations of this gene to articles via ¹Entrez Gene, ²UniProtKB/Swiss-Prot, ³HGNC, ⁴GAD, ⁵PharmGKB, ⁶HMDB, ⁷DrugBank, ⁸UniProtKB/TrEMBL, ⁹ Novoseek, and/or ¹⁰fRNAdb)
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PubMed articles for CKMT1B gene, integrated from 9 sources (see all 46):
(articles sorted by number of sources associating them with CKMT1B)

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world of online information

Crystal structure of human ubiquitous mitochondrial creatine kinase. (PubMed id 10737943)^{1, 2, 9} Eder M.... Schlattner U. (2000)
Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)^{1, 2} Ota T.... Sugano S. (2004)
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
Isolation and characterization of the gene and cDNA encoding human mitochondrial creatine kinase. (PubMed id 2914937)^{1, 2} Haas R.C....Strauss A.W. (1989)
Regulation of creatine kinase isoenzymes in human placenta during early, mid-, and late gestation. (PubMed id 8923416)^{1, 9} Thomure M.F....Payne R.M. (1996)
A quantitative approach to membrane binding of human ubiquitous mitochondrial creatine kinase using surface plasmon resonance. (PubMed id 11768757)^{1, 9} Schlattner U. and Wallimann T. (2000)
ASB9 interacts with ubiquitous mitochondrial creatine kinase and inhibits mitochondrial function. (PubMed id 20302626)^{1, 9} Kwon S....Kwon H.J. (2010)
Creatine kinase and creatine transporter in normal, wounded, and diseased skin. (PubMed id 11874479)^{1, 9} Schlattner U....Wallimann T. (2002)
Expression of the mitochondrial creatine kinase genes. (PubMed id 7808456)^{1, 9} Payne R.M. and Strauss A.W. (1994)
The ubiquitous mitochondrial creatine kinase gene maps to a conserved region on human chromosome 15q15 and mouse chromosome 2 bands F1-F3. (PubMed id 7896282)^{1, 9} Steeghs K....Wieringa B. (1994)

(in PubMed, OMIM, and NCBI Bookshelf)
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		AND	OR
Aliases
Free Text

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(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
About This Section

Entrez Gene: 1159	HGNC: 1995	AceView: CKMT1	Ensembl:ENSG00000237289	euGenes: HUgn1159
ECgene: CKMT1B	Kegg: 1159	H-InvDB: CKMT1B

(According to HUGE)
About This Section

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section

Name	Description
PharmGKB entry for CKMT1B	Pharmacogenomics, SNPs, Pathways
ATLAS Chromosomes in Cancer entry for CKMT1B	Genetics and Cytogenetics in Oncology and Haematology

Intellectual Property for CKMT1B gene
(Patent information from GeneIP, Licensable technologies from WIS Yeda, Salk, Tufts, IP news from LifeMap Sciences, Inc.)

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Patent Information for CKMT1B gene:
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creatine kinase, mitochondrial 1B

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creatine kinase, mitochondrial 1B

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