CKM Gene

Aliases
for CKM gene

Previous GC identifers: GC19M046454 GC19M046200 GC19M050485 GC19M050501 GC19M042241

Summaries
for CKM gene

Genomic Views
for CKM gene

RefSeq DNA sequence:

NC_000019.9  NC_018930.1  NT_011109.16  

SwitchGear Promoter luciferase reporter plasmid: CKM promoter sequence

QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CKM

CKM Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)


GeneLoc information about chromosome 19         GeneLoc Exon Structure

GeneLoc location for GC19M045809:  view genomic region     (about GC identifiers)

Proteins
for CKM gene

1 PDB 3D structure from and Proteopedia for CKM:

1I0E (3D)    

Explore the universe of human proteins at neXtProt for CKM: NX_P06732

Post-translational modifications:

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	OriGene Purified Protein: CKM OriGene Protein Over-expression Lysate: CKM OriGene Custom Protein Services for CKM
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	Novus Biologicals CKM Proteins Novus Biologicals CKM Lysates
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	ProSpec Recombinant Protein for CKM
	Uscn Proteins for CKM

Gene Ontology (GO): 2 cellular component terms (GO ID links to tree view):    About this table

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	R&D Systems Antibodies for CKM (Creatine Kinase, Muscle/CKMM)
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	Uscn Antibodies for CKM
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	OriGene Custom Immunoassay Development Browse OriGene Fluorogenic Cell Assay Kits
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	GenScript Custom Assay Services for CKM
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	Uscn ELISAs and CLIAs for CKM

Protein Domains /
Families
for CKM gene

ProtoNet protein and cluster: P06732

Function
for CKM gene

miRNA Products:		OriGene 3'-UTR Clone: CKM Browse MicroRNA Expression Plasmids
		QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat CKM
		3 QIAGEN miScript miRNA Assays for microRNAs that regulate CKM:
		hsa-miR-3140-3p hsa-miR-663 hsa-miR-1908
		SwitchGear 3'UTR luciferase reporter plasmid: CKM 3' UTR sequence

Inhib. RNA Products:		Browse for Gene Knock-down Tools from EMD Millipore
		OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CKM (see all 7) OriGene shRNA RFP: CKM OriGene siRNA: CKM
		QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CKM

Gene Editing Products:

DNA2.0 Custom Protein Engineering Service for CKM

Clone Products:		Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
		OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CKM (see all 3) OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CKM (see all 2) OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
		GenScript: all cDNA clones in your preferred vector: CKM (NM_001824)
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		Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CKM

Cell Line Products:		GenScript Custom overexpressing Cell Line Services for CKM
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In Situ Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CKM

Gene Ontology (GO): 2 molecular function terms (GO ID links to tree view):    About this table

(inferred from 2 alleles) (MGI details for Ckm)

Pathways & Interactions
for CKM gene

	Super-pathway	contained gene-specific pathways
1	Metabolism	Metabolism 1.00 Metabolic pathways 0.38
2	Arginine and proline metabolism	Arginine and proline metabolism 1.00 Urea cycle and metabolism of amino groups 0.36
3	creatine-phosphate biosynthesis	creatine-phosphate biosynthesis 1.00 Creatine metabolism 0.38
4	Metabolism of amino acids and derivatives	Metabolism of amino acids and derivatives 1.00
5	AMPK Enzyme Complex Pathway	AMPK Enzyme Complex Pathway 1.00

1 Downloadable PowerPoint Slide of QIAGEN Pathway Central Maps for CKM

AMPK Enzyme Complex Pathway

3 BioSystems Pathways for CKM

	creatine-phosphate biosynthesis
	Regulation of retinoblastoma protein
	Urea cycle and metabolism of amino groups

3        Reactome Pathways for CKM

	Creatine metabolism
	Metabolism
	Metabolism of amino acids and derivatives

2         Kegg Pathways  (Kegg details for CKM)

	Arginine and proline metabolism
	Metabolic pathways

Gene Ontology (GO): 4 biological process terms (GO ID links to tree view):    About this table

Drugs & Compounds
for CKM gene

Transcripts
for CKM gene

Expression
for CKM gene

CKM expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: ATCCCCGCCC

1 LifeMap In Vivo Development Anatomical Compartment/Cell
	Tissue Anatomical Compartment Cell			Category (developmental path)
	AdiposeInterscapular Brown Adipose Depot			Adipose
Expression: Positive    Negative     Selective marker Experimental details: Curated     Microarrays     In-situ hybridization

Primer Products:		OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CKM Browse OriGene validated miRNA SYBR primer pairs
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In Situ Assay Products:

Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CKM

Orthologs
for CKM gene

Paralogs
for CKM gene

Paralogs for CKM gene

CKB²  CKMT1B²  CKMT2²  CKMT1A²  

4 SIMAP similar genes for CKM using alignment to 1 protein entry:     KCRM_HUMAN:

CKB    CKMT2    CKMT1B    CKMT1A

CKM for paralogs           About GeneDecksing

Genomic Variants
for CKM gene

10/389 NCBI SNPs in CKM are shown (see all 389)     About this table

Genomic Data					Transcription Related Data				Allele Frequencies
SNP ID	Valid	Clinical significance	Chr 19 pos	Sequence	#	AA Chg	Type	More	#	Allele freq	Pop	Total sample	More
-1st2nd3rd	-1st2nd3rd	-1st2nd3rd	-1st2nd3rd	--	--	--	-1st2nd3rd	--	--	-1st2nd3rd	-1st2nd3rd	-1st2nd3rd
rs81119891,2	C,F,A,H,	--	45809208(+)	AGCCAT/CGGCAG	1	--	int1		29		NS EA NA WA CSA	3084
rs178756311,2	C,	--	45809265(-)	GTCCCG/ATCTGA	1	--	int1		2		NS	80
rs1896109641,2		--	45809333(+)	CTCAAA/CACTGG	1	--	int1		0	--	--	--	--
rs178756301,2	C,F,	--	45809344(-)	CCCAAC/TGGTCT	1	--	int1		4		NS WA	200
rs1816688081,2		--	45809554(+)	AACTTA/TGCCTC	1	--	int1		0	--	--	--	--
rs1118437491,2	C	--	45809672(+)	AAGCTT/AAGGCC	1	--	ut31		1		CSA	1
rs753793651,2		--	45809685(+)	CAATGC/TTTTTA	1	--	ut31		1		NA	120
rs1861891121,2		--	45809697(+)	TTATCA/GCTTTG	1	--	ut31		0	--	--	--	--
rs178756291,2	C,F,H,	--	45809750(-)	TCTAGT/CTAATG	1	--	ut31 ese3		14		NS NA WA	1526
rs178756281,2	C,F,	--	45809886(-)	CTCTCT/CCCACC	1	--	ut31 ese3		4		NS WA	210

HapMap Linkage Disequilibrium report for CKM (45809671 - 45826235 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
      Database of Genomic Variants (DGV) variations for CKM: --
Human Gene Mutation Database (HGMD): CKM

SABiosciences Cancer Mutation PCR Assays

QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CKM

DNA2.0 Custom Variant and Variant Library Synthesis for CKM

Disorders / Diseases
for CKM gene

20/39 diseases for CKM

10/15 Novoseek disease relationships for CKM gene (see all 15)    About this table

Publications
for CKM gene

PubMed articles for CKM gene, integrated from 9 sources (see all 246) (see top 10): (articles sorted by number of sources associating them with CKM)

Utopia: connect your pdf to the dynamic world of online information

1. Is there an association between ACE and CKMM polymorphisms and cycling performance status during 3-week races? (PubMed id 16037885)^{1, 4, 9} Lucia A....Earnest C.P. (2005)
2. Muscle-specific creatine kinase gene polymorphism and running economy responses to an 18-week 5000-m training programme. (PubMed id 17000714)^{1, 7, 9} Zhou D.Q....Wen L. (2006)
3. Muscle creatine kinase isoenzyme expression in adult human brain. (PubMed id 1690725)^{1, 2, 9} Hamburg R.J.... Perryman M.B. (1990)
4. [An A/G polymorphism in muscle-specific creatine kinase gene in Han population in Northern China] (PubMed id 16120572)^{1, 4, 9} Zhou D.Q....Gong L. (2005)
5. The caregene study: muscle-specific creatine kinase gene and aerobic power in coronary artery disease. (PubMed id 16079652)^{1, 4, 9} Defoor J....Vanhees L. (2005)
6. Crystallization and preliminary X-ray analysis of human muscle creatine kinase. (PubMed id 10089465)^{1, 2, 9} Tang L.... Lin Z.J. (1999)
7. The DNA sequence and biology of human chromosome 19. (PubMed id 15057824)^{1, 2} Grimwood J.... Lucas S.M. (2004)
8. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)^{1, 2} Gerhard D.S....Malek J. (2004)
9. Developmental regulation and tissue-specific expression of the human muscle creatine kinase gene. (PubMed id 2903158)^{1, 2} Trask R.V.... Billadello J.J. (1988)
10. cDNA cloning and mapping of the human creatine kinase M gene to 19q13. (PubMed id 3031982)^{1, 2} Nigro J.M....Martin-Deleon P. (1987)
11. Isolation and sequence analysis of a full-length cDNA for human M creatine kinase. (PubMed id 3778496)^{1, 2} Perryman M.B.... Roberts R. (1986)
12. A long-range restriction map of the human chromosome 19q13 region: close physical linkage between CKMM and the ERCC1 and ERCC2 genes. (PubMed id 2309701)^{1, 9} Smeets H....Siciliano M.J. (1990)
13. Spermatogenesis-related change in the synthesis of the creatine kinase B-type and M-type isoforms in human spermatozoa. (PubMed id 2331374)^{1, 9} Huszar G. and Vigue L. (1990)
14. The generation of the oxidized form of creatine kinase is a negative regulation on muscle creatine kinase. (PubMed id 17303563)^{1, 9} Zhao T.J....Zhou H.M. (2007)
15. Exploring the role of the active site cysteine in human muscle creatine kinase. (PubMed id 16981706)^{1, 9} Wang P.F....McLeish M.J. (2006)
16. Capture of monomeric refolding intermediate of human muscle creatine kinase. (PubMed id 16373479)^{1, 9} Li S....Zhou H.M. (2006)
17. Does the polygenic profile determine the potential for becoming a world-class athlete? Insights from the sport of rowing. (PubMed id 19422651)^{1, 9} Santiago C....Lucia A. (2009)
18. CK-MM and ACE genotypes and physiological prediction of the creatine kinase response to exercise. (PubMed id 17478608)^{1, 9} Heled Y....Deuster P.A. (2007)
19. Isoleucine 69 and valine 325 form a specificity pocket in human muscle creatine kinase. (PubMed id 15504039)^{1, 9} Novak W.R....Babbitt P.C. (2004)
20. The short MCK1350 promoter/enhancer allows for sufficient dystrophin expression in skeletal muscles of mdx mice. (PubMed id 11922612)^{1, 9} Larochelle N....Lochmuller H. (2002)
21. Creatine kinase MM TaqI and methylenetetrahydrofolate reductase C677T and A1298C gene polymorphisms influence exercise-induced C-react ive protein levels. (PubMed id 21516340)¹ Miranda-Vilela A.L....Klautau-Guimaraes M.d.e. .N. (2012)
22. Comparison of the prognosis of spontaneous and percuta neous coronary intervention-related myocardial infarction. (PubMed id 23122801)¹ Leonardi S....Mahaffey K.W. (2012)
23. Creatine kinase MM TaqI and methylenetetrahydrofolate reductase C677T and A1298C gene polymorphisms influence exercise-induced C-react ive protein levels. (PubMed id 21706313)¹ Miranda-Vilela A.L....Klautau-Guimaraes M.d.e. .N. (2012)
24. The Brd4 extraterminal domain confers transcription a ctivation independent of pTEFb by recruiting multiple proteins, including NSD3. (PubMed id 21555454)¹ Rahman S....Howley P.M. (2011)
25. Impact of plaque morphology on creatine kinase-MB ele vation in patients with elective stent implantation. (PubMed id 20591515)¹ Yonetsu T....Isobe M. (2011)
26. Dissimilarity in the folding of human cytosolic creati ne kinase isoenzymes. (PubMed id 21931810)¹ Wang Y....Yan Y.B. (2011)
27. Muscle creatine kinase deficiency triggers both actin depolymerization and desmin disorganization by advanced glycation end products in dilated cardiomyopathy. (PubMed id 21768101)¹ Diguet N....Mericskay M. (2011)
28. Diagnosis of ischemic heart disease using CK-MB, trop onin-I and ischemia modified albumin. (PubMed id 21456469)¹ Dawie J....Azazh A. (2011)
29. Cardiac troponin T and creatine kinase predict mid-te rm infarct size and left ventricular function after acute myocardial infarction : a cardiac MR study. (PubMed id 21448949)¹ Mayr A....Metzler B. (2011)
30. Slow skeletal muscle myosin-binding protein-C (MyBPC1 ) mediates recruitment of muscle-type creatine kinase (CK) to myosin. (PubMed id 21426302)¹ Chen Z....Zhou H.M. (2011)
31. Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)¹ Danielsen J.M....Nielsen M.L. (2011)
32. Temporal changes in circulating P-selectin, plasminog en activator inhibitor-1, magnesium, and creatine kinase after percutaneous cor onary intervention. (PubMed id 20669347)¹ Ying S.Q....Wang J.A. (2010)
33. Dengue hemorrhagic fever is associated with polymorph isms in JAK1. (PubMed id 20588308)¹ Silva L.K....Teixeira M.G. (2010)
34. The N terminus of Cbl-c regulates ubiquitin ligase ac tivity by modulating affinity for the ubiquitin-conjugating enzyme. (PubMed id 20525694)¹ Ryan P.E....Lipkowitz S. (2010)
35. CK-MM gene polymorphism does not influence the blood CK activity levels after exhaustive eccentric exercise. (PubMed id 20157874)¹ Yamin C....Duarte J.A. (2010)
36. Association of Single-Nucleotide Polymorphisms From 1 7 Candidate Genes With Baseline Symptom-Limited Exercise Test Duration and Decr ease in Duration Over 20 Years: The Coronary Artery Risk Development in Young A dults (CARDIA) Fitness Study. (PubMed id 20952631)¹ Sarzynski M.A....Bouchard C. (2010)
37. Dissecting the key residues crucial for the species-s pecific thermostability of muscle-type creatine kinase. (PubMed id 20558199)¹ Gao Y.S....Zhou H.M. (2010)
38. Variation at the NFATC2 locus increases the risk of t hiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipr il and rosiglitazone Medication (DREAM) study. (PubMed id 20628086)¹ Bailey S.D....Anand S. (2010)
39. Elevated CK-MB values after routine angioplasty predi cts worse long-term prognosis in low-risk patients. (PubMed id 19670037)¹ Vikenes K....Nordrehaug J.E. (2010)
40. Predictive value of cardiac troponin-I compared to cr eatine kinase-myocardial band for the assessment of infarct size as measured by cardiac magnetic resonance. (PubMed id 20588136)¹ Di Chiara A....Fioretti P.M. (2010)
41. Single nucleotide polymorphisms in the myostatin (MST N) and muscle creatine kinase (CKM) genes are not associated with elite enduran ce performance. (PubMed id 20536908)¹ DAPring F....Bouchard C. (2010)
42. Maternal genes and facial clefts in offspring: a comp rehensive search for genetic associations in two population-based cleft studies from Scandinavia. (PubMed id 20634891)¹ Jugessur A....Murray J.C. (2010)
43. Long-term prognostic value of creatine kinase-myocard ial band mass after cardiac surgery in low-risk patients with stable angina. (PubMed id 19039220)¹ Vikenes K....Nordrehaug J.E. (2009)
44. Changes in serum cartilage oligomeric matrix protein (COMP), plasma CPK and plasma hs-CRP in relation to running distance in a marathon (42.195 km) and an ultra-marathon (200 km) race. (PubMed id 19125286)¹ Kim H.J....Kim C.K. (2009)
45. Gene-centric association signals for lipids and apoli poproteins identified via the HumanCVD BeadChip. (PubMed id 19913121)¹ Talmud P.J.... . (2009)
46. Cardiovascular disease testing on the Dimension Vista system: biomarkers of acute coronary syndromes. (PubMed id 19523464)¹ Kelley W.E....Christenson R.H. (2009)
47. The effects of prior calcium channel blocker therapy on creatine kinase-MB levels after percutaneous coronary interventions. (PubMed id 19337554)¹ Gulmez O....Muderrisoglu H. (2008)
48. Duchenne muscular dystrophy and idiopathic hyperCKemia in the same family. (PubMed id 18833644)¹ Eeg-Olofsson O....Dahl N. (2008)
49. Muscle RING-finger protein-1 (MuRF1) as a connector o f muscle energy metabolism and protein synthesis. (PubMed id 18222470)¹ Koyama S....Sorimachi H. (2008)
50. Significance of CK-elevation in noncompaction with re gard to cardiac and neuromuscular disease. (PubMed id 18055044)¹ Finsterer J....Krugluger W. (2008)
51. World-class performance in lightweight rowing: Is it genetically influenced? A comparison with cyclists, runners and non-athletes. (PubMed id 18801770)¹ Muniesa C.A....Lucia A. (2008)
52. Cardiac involvement of major thalassemia and evaluation of total serum creatine kinase and creatine kinase-mB isoenzyme and cardiac troponinI in these patients. (PubMed id 18810980)¹ Sakha K....Rezamand A. (2008)
53. ACE ID genotype affects blood creatine kinase response to eccentric exercise. (PubMed id 17885020)¹ Yamin C....Amir R.E. (2007)
54. Bioenergetic and functional consequences of bone marr ow-derived multipotent progenitor cell transplantation in hearts with postinfar ction left ventricular remodeling. (PubMed id 17389266)⁷ Zeng L....Zhang J. (2007)
55. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PubMed id 16344560)¹ Kimura K.... Sugano S. (2006)
56. CK-MM autoantibodies: prevalence, immune complexes, and effect on CK clearance. (PubMed id 16810680)¹ Warren G.L....Clarkson P.M. (2006)
57. The identification of myocilin-associated proteins in the human trabecular meshwork. (PubMed id 16289162)¹ Fautsch M.P....Johnson D.H. (2006)
58. How many drug targets are there? (PubMed id 17139284)⁷ Overington J.P....Hopkins A.L. (2006)
59. Drugs, their targets and the nature and number of dru g targets. (PubMed id 17016423)⁷ Imming P....Meyer A. (2006)
60. Does creatinine kinase-MB elevation after percutaneous coronary intervention predict outcomes in 2005? Periprocedural cardiac enzyme elevation predicts adverse outcomes. (PubMed id 16087811)¹ Bhatt D.L. and Topol E.J. (2005)
61. Does creatinine kinase-MB elevation after percutaneous coronary intervention predict outcomes in 2005? Cardiac enzyme elevation after successful percutaneous coronary intervention is not an independent predictor of adverse outcomes. (PubMed id 16092153)¹ Cutlip D.E. and Kuntz R.E. (2005)
62. MURF-1 and MURF-2 target a specific subset of myofibrillar proteins redundantly: towards understanding MURF-dependent muscle ubiquitination. (PubMed id 15967462)¹ Witt S.H.... Labeit S. (2005)
63. Comprehensive proteomic analysis of interphase and mi totic 14-3-3-binding proteins. (PubMed id 15161933)¹ Meek S.E....Piwnica-Worms H. (2004)
64. Muscle-type creatine kinase interacts with central domains of the M-band proteins myomesin and M-protein. (PubMed id 12972258)¹ Hornemann T....Wallimann T. (2003)
65. Hyperubiquitination of proteins in dilated cardiomyop athy. (PubMed id 12601813)¹ Weekes J....Dunn M.J. (2003)
66. Subcellular targeting of metabolic enzymes to titin in heart muscle may be mediated by DRAL/FHL-2. (PubMed id 12432079)¹ Lange S.... Ehler E. (2002)
67. Myocardial creatine kinase expression after left ventricular assist device support. (PubMed id 12039490)¹ Park S.J....Bache R.J. (2002)
68. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)¹ Strausberg R.L....Marra M.A. (2002)
69. Creatine and creatinine metabolism. (PubMed id 10893433)¹ Wyss M. and Kaddurah-Daouk R. (2000)
70. The Protein Data Bank. (PubMed id 10592235)⁷ Berman H.M....Bourne P.E. (2000)
71. Subunit conformation and dynamics in a heterodimeric protein: studies of the hybrid isozyme of creatine kinase. (PubMed id 9748661)¹ Grossman S.H. and Sellers D.S. (1998)
72. Sequence verification of human creatine kinase (43 kDa) isozymes by high-resolution tandem mass spectrometry. (PubMed id 8524781)¹ Wood T.D....McLafferty F.W. (1995)
73. Creatine kinase in non-muscle tissues and cells. (PubMed id 7808454)¹ Wallimann T. and Hemmer W. (1994)
74. Functional aspects of creatine kinase in brain. (PubMed id 7805577)¹ Hemmer W. and Wallimann T. (1993)
75. Intracellular compartmentation, structure and functio n of creatine kinase isoenzymes in tissues with high and fluctuating energy dem ands: the 'phosphocreatine circuit' for cellular energy homeostasis. (PubMed id 1731757)⁷ Wallimann T....Eppenberger H.M. (1992)
76. Isolation and characterization of the gene and cDNA encoding human mitochondrial creatine kinase. (PubMed id 2914937)¹ Haas R.C....Strauss A.W. (1989)
77. Creatine kinase activity in normal and Duchenne muscular dystrophy fibroblasts. (PubMed id 7057800)¹ Davis M.H....Gruenstein E. (1982)
78. Biochemical markers of early and late spermatogenesis: relationship between the lactate dehydrogenase-X and creatine kinase-M isoform concentrations in human spermatozoa. (PubMed id 9052941)⁹ Lalwani S....Huszar G. (1996)
79. Creatine kinase gene mutation in a patient with muscle creatine kinase deficiency. (PubMed id 11673364)⁹ Yamamichi H....Koshiba M. (2001)
80. Absence of MEF2 binding to the A/T-rich element in the muscle creatine kinase (MCK) enhancer correlates with lack of early expression of the MCK gene in embryonic mammalian muscle. (PubMed id 8993831)⁹ Ferrari S....Cossu G. (1997)
81. Assessment of a creatine kinase isoform M defect as a cause of myotonic dystrophy and the characterization of two novel CKMM polymorphisms. (PubMed id 2016086)⁹ Bailly J....Korneluk R.G. (1991)
82. p53-dependent activation of the mouse MCK gene promoter: identification of a novel p53-responsive sequence and evidence for cooperation between distinct p53 binding sites. (PubMed id 7488858)⁹ Jackson P....Braithwaite A. (1995)
83. Spatial distribution of 'tissue-specific' antigens in the developing human heart and skeletal muscle. I. An immunohistochemical analysis of creatine kinase isoenzyme expression patterns. (PubMed id 2240609)⁹ Wessels A....Moorman A.F. (1990)
84. A novel site in the muscle creatine kinase enhancer is required for expression in skeletal but not cardiac muscle. (PubMed id 8617727)⁹ Fabre-Suver C. and Hauschka S.D. (1996)
85. Tight linkage of creatine kinase (CKMM) to myotonic dystrophy on chromosome 19. (PubMed id 2300239)⁹ Yamaoka L.H....Mathieu J. (1990)
86. Regulation of muscle creatine kinase by phosphorylation in normal and diabetic hearts. (PubMed id 18979206)⁹ Lin G....MacLeod K.M. (2009)
87. Akt1 and Akt2 differently regulate muscle creatine kinase and myogenin gene transcription in insulin-induced differentiation of C2C12 myoblasts. (PubMed id 11861503)⁹ Sumitani S....Kasayama S. (2002)
88. [Human creatine kinase deficiency] (PubMed id 12166076)⁹ Yamamichi H. and Ohkawa J. (2002)
89. Linkage between a muscle-specific CK gene marker and VO2max in the HERITAGE Family Study. (PubMed id 10331890)⁹ Rivera M.A....Bouchard C. (1999)
90. Synergistic transcriptional activation of the MCK promoter by p53: tetramers link separated DNA response elements by DNA looping. (PubMed id 9464547)⁹ Jackson P....Barrett J. (1998)
91. Homeodomain protein MHox and MADS protein myocyte enhancer-binding factor-2 converge on a common element in the muscle creatine kinase enhancer. (PubMed id 8206996)⁹ Cserjesi P....Olson E.N. (1994)
92. Lack of toxicity of alpha-sarcoglycan overexpression supports clinical gene transfer trial in LGMD2D. (PubMed id 18525034)⁹ Rodino-Klapac L.R....Mendell J.R. (2008)
93. Hybrid retroviral vector with MCK enhancers inserted in LTR for stable and specific expression of human factor IX in skeletal muscle. (PubMed id 15198894)⁹ Wang J.M....Xue J.L. (2004)
94. Analysis of the DNA-binding properties of MyoD, myogenin, and E12 by fluorescence anisotropy. (PubMed id 12196028)⁹ Maleki S.J....Hurlburt B.K. (2002)
95. The isoenzyme-diagnostic regions of muscle-type creatine kinase, the M-260 and M-300 box, are not responsible for its binding to the myofibrillar M-band. (PubMed id 9808283)⁹ Stolz M....Wallimann T. (1998)
96. p53 protein is activated during muscle differentiation and participates with MyoD in the transcription of muscle creatine kinase gene. (PubMed id 9690516)⁹ Tamir Y. and Bengal E. (1998)
97. Inhibition of myogenesis by multiple cyclin-Cdk complexes. Coordinate regulation of myogenesis and cell cycle activity at the level of E2F. (PubMed id 8995365)⁹ Guo K. and Walsh K. (1997)
98. Reduction of four-and-a-half LIM-protein 2 expression occurs in human left ventricular failure and leads to altered localization and reduced activity of metabolic enzymes. (PubMed id 19327508)⁹ Bovill E....Shaw T. (2009)
99. Quantitative proteomic identification of MAZ as a transcriptional regulator of muscle-specific genes in skeletal and cardiac myocytes. (PubMed id 18710939)⁹ Himeda C.L....Hauschka S.D. (2008)
100. Analysis of muscle creatine kinase regulatory elements in recombinant adenoviral vectors. (PubMed id 10899824)⁹ Hauser M.A....Chamberlain J.S. (2000)
101. Cytoplasmic extrusion and the switch from creatine kinase B to M isoform are completed by the commencement of epididymal transport in human and stallion spermatozoa. (PubMed id 9537287)⁹ Huszar G....Johnson L. (1998)
102. E1A-mediated inhibition of myogenesis correlates with a direct physical interaction of E1A12S and basic helix-loop-helix proteins. (PubMed id 8393137)⁹ Taylor D.A....Kraus W.E. (1993)
103. Rabbit muscle creatine kinase: genomic cloning, sequencing, and analysis of upstream sequences important for expression in myocytes. (PubMed id 2057360)⁹ Yi T.M....Schimmel P. (1991)
104. Linkage disequilibrium detected between dystrophia myotonica and APOC2 locus in the Finnish population. (PubMed id 1977684)⁹ Nokelainen P....Peltonen L. (1990)
105. Effect of macro-creatine kinase and increased creatine kinase BB on the rapid diagnosis of patients with suspected acute myocardial infarction in the emergency department. (PubMed id 16173202)⁹ Serdar M.A....Kutluay T. (2005)
106. An unusually low pK(a) for Cys282 in the active site of human muscle creatine kinase. (PubMed id 11570870)⁹ Wang P.F....Kenyon G.L. (2001)
107. Role of creatine kinase isoenzymes on muscular and cardiorespiratory endurance: genetic and molecular evidence. (PubMed id 11708401)⁹ Echegaray M. and Rivera M.A. (2001)
108. Kinetics of slow reversible inhibition of human muscle creatine kinase by planar anions. (PubMed id 9756613)⁹ Luo W....Zhou H.M. (1998)
109. Myofibrillar interaction of cytosolic creatine kinase (CK) isoenzymes: allocation of N-terminal binding epitope in MM-CK and BB-CK. (PubMed id 9547297)⁹ Stolz M. and Wallimann T. (1998)
110. Bone morphogenetic protein-2 inhibits terminal differentiation of myogenic cells by suppressing the transcriptional activity of MyoD and myogenin. (PubMed id 9024793)⁹ Katagiri T....Suda T. (1997)
111. Muscle-specific creatine kinase gene polymorphism and VO2max in the HERITAGE Family Study. (PubMed id 9346161)⁹ Rivera M.A....Bouchard C. (1997)
112. The prognostic value of serum troponin T in unstable angina. (PubMed id 8793576)⁹ Gokhan Cin V....Kaptanoglu B. (1996)
113. Use of creatine kinase isoforms for diagnosis of infarct artery patency after thrombolytic therapy with streptokinase. (PubMed id 8269212)⁹ Norris R.M....White H.D. (1993)
114. Effect of extracorporeal shockwave lithotripsy for urolithiasis on concentrations of creatine kinase isozymes in patient serum and urine. (PubMed id 1413305)⁹ Hasegawa S....Miyake K. (1992)
115. [S100a0 protein and creatine kinase isozymes (CK-B & CK-M) in serum and urine might be useful markers for non specific tissue damages by extracorporeal shockwave lithotripsy (ESWL)] (PubMed id 1921018)⁹ Hasegawa S....Miyake K. (1991)
116. Differential trans-activation of a muscle-specific enhancer by myogenic helix-loop-helix proteins is separable from DNA binding. (PubMed id 1847137)⁹ Chakraborty T....Olson E. (1991)
117. Myogenin resides in the nucleus and acquires high affinity for a conserved enhancer element on heterodimerization. (PubMed id 2163343)⁹ Brennan T.J. and Olson E.N. (1990)
118. Correction of multiple striated muscles in murine Pompe disease through adeno-associated virus-mediated gene therapy. (PubMed id 18560415)⁹ Sun B....Koeberl D.D. (2008)
119. Molecular mechanism of transforming growth factor-beta-mediated inhibition of growth arrest and differentiation in a myoblast cell line. (PubMed id 18211587)⁹ Murakami M....Nakamura M. (2008)
120. Muscle creatine kinase/SV40 hybrid promoter for muscle-targeted long-term transgene expression. (PubMed id 17203206)⁹ Takeshita F....Sasaki S. (2007)
121. Inhibition of glycogen synthase kinase-3beta activity is sufficient to stimulate myogenic differentiation. (PubMed id 16162663)⁹ van der Velden J.L....Schols A.M. (2006)
122. Sodium barbital is a slow reversible inactivator of rabbit-muscle creatine kinase. (PubMed id 16609694)⁹ Shi F....Wu P. (2006)
123. Formation and properties of hairpin and tetraplex structures of guanine-rich regulatory sequences of muscle-specific genes. (PubMed id 15908587)⁹ Yafe A....Fry M. (2005)
124. Effect of varicocelectomy on sperm creatine kinase, HspA2 chaperone protein (creatine kinase-M type), LDH, LDH-X, and lipid peroxidation product levels in infertile men with varicocele. (PubMed id 16140088)⁹ Yesilli C....Mungan A. (2005)
125. Effects of oral creatine and resistance training on myogenic regulatory factor expression. (PubMed id 12783039)⁹ Willoughby D.S. and Rosene J.M. (2003)
126. Structure of human muscle creatine kinase. (PubMed id 11517911)⁹ Shen Y.Q....Lin Z.J. (2001)
127. Differential biological activities of mammalian Id proteins in muscle cells. (PubMed id 10047451)⁹ Melnikova I.N....Christy B.A. (1999)
128. Morphometric assessment of mature and diminished-matu rity human spermatozoa: sperm regions that reflect differences in maturity. (PubMed id 10438418)⁹ Gergely A....Huszar G. (1999)
129. Absence of myofibrillar creatine kinase and diaphragm isometric function during repetitive activation. (PubMed id 9516180)⁹ LaBella J.J....Watchko J.F. (1998)
130. Bed rest decreases mechanically induced myofiber wounding and consequent wound-mediated FGF release. (PubMed id 9688737)⁹ Clarke M.S....Feeback D.L. (1998)
131. Functional coupling of creatine kinases in muscles: species and tissue specificity. (PubMed id 9746324)⁹ Ventura-Clapier R....Anflous K. (1998)
132. bFGF induces BCK promoter-driven expression in muscle via increased binding of a nuclear protein. (PubMed id 9252460)⁹ Kim L....Ritchie M.E. (1997)
133. Muscle-specific creatine kinase gene polymorphisms in elite endurance athletes and sedentary controls. (PubMed id 9372480)⁹ Rivera M.A....Bouchard C. (1997)
134. Inhibition of muscle-specific gene expression by Id3: requirement of the C-terminal region of the protein for stable expression and function. (PubMed id 9016574)⁹ Chen B....Lim R.W. (1997)
135. Sperm plasma membrane remodeling during spermiogenetic maturation in men: relationship among plasma membrane beta 1,4-galactosyltransferase, cytoplasmic creatine phosphokinase, and creatine phosphokinase isoform ratios. (PubMed id 9096886)⁹ Huszar G....Shur B.D. (1997)
136. Creatine kinase isoform electrophoresis for the early confirmation of myocardial infarction detected by timed sequential CK slope analysis. (PubMed id 7824414)⁹ Chattington P....Neithercut W.D. (1994)
137. Expression of the mitochondrial creatine kinase genes. (PubMed id 7808456)⁹ Payne R.M. and Strauss A.W. (1994)
138. Activation of muscle-specific transcription by myogenic helix-loop-helix proteins. (PubMed id 1341046)⁹ Olson E. (1992)
139. Fos and Jun repress transcriptional activation by myogenin and MyoD: the amino terminus of Jun can mediate repression. (PubMed id 1313772)⁹ Li L....Olson E.N. (1992)
140. Different E-box regulatory sequences are functionally distinct when placed within the context of the troponin I enhancer. (PubMed id 1329039)⁹ Yutzey K.E. and Konieczny S.F. (1992)
141. DNA binding and transcriptional regulatory activity o f mammalian achaete-scute homologous (MASH) proteins revealed by interaction wi th a muscle-specific enhancer. (PubMed id 1314394)⁹ Johnson J.E....Anderson D.J. (1992)
142. Molecular analysis of the myoadenylate deaminase deficiencies. (PubMed id 1370861)⁹ Sabina R.L.... Holmes E.W. (1992)
143. Prenatal diagnosis of myotonic dystrophy using closel y linked flanking markers. (PubMed id 2002492)⁹ Lavedan C....Junien C. (1991)
144. Immunohistochemical study of creatine kinase isozymes in the human upper limb bud. (PubMed id 1950416)⁹ Shinohara H....Kato K. (1991)
145. Identification by protein microsequencing of a proteinase-V8-cleavage site in a folding intermediate of chick muscle creatine kinase. (PubMed id 1684894)⁹ Morris G.E. and Jackson P.J. (1991)
146. A new polymorphic probe which defines the region of chromosome 19 containing the myotonic dystrophy locus. (PubMed id 1971149)⁹ Johnson K....Rundle S. (1990)
147. Nfix regulates fetal-specific transcription in develo ping skeletal muscle. (PubMed id 20178747)⁹ Messina G....Cossu G. (2010)
148. Desmin-regulated lentiviral vectors for skeletal musc le gene transfer. (PubMed id 19935780)⁹ Talbot G.E....Antoniou M.N. (2010)
149. Frataxin deficiency causes upregulation of mitochondrial Lon and ClpP proteases and severe loss of mitochondrial Fe-S proteins. (PubMed id 19154341)⁹ Guillon B....Bouton C. (2009)
150. Dynamic expression pattern of distinct genes in the p resomitic and somitic mesoderm during Xenopus development. (PubMed id 19598125)⁹ Bourdelas A....Shi D.L. (2009)
151. Unique among unique. Is it genetically determined? (PubMed id 18662936)⁹ Gonzalez-Freire M....Lucia A. (2009)
152. Myostatin reduces Akt/TORC1/p70S6K signaling, inhibit ing myoblast differentiation and myotube size. (PubMed id 19357233)⁹ Trendelenburg A.U....Glass D.J. (2009)
153. Progressive decrease of phosphocreatine, creatine and creatine kinase in skeletal muscle upon transformation to sarcoma. (PubMed id 18485002)⁹ Patra S....Ray M. (2008)
154. Effects of allicin supplementation on plasma markers of exercise-induced muscle damage, IL-6 and antioxidant capacity. (PubMed id 18305954)⁹ Su Q.S....Zhang H. (2008)
155. Progress toward a nonviral gene therapy protocol for the treatment of anemia. (PubMed id 17376007)⁹ Sebestyen M.G....Wolff J.A. (2007)
156. Fertility testing and ICSI sperm selection by hyaluro nic acid binding: clinical and genetic aspects. (PubMed id 17509211)⁹ Huszar G....Ozkavukcu S. (2007)
157. Autologous transplantation of muscle precursor cells modified with a lentivirus for muscular dystrophy: human cells and primate mode ls. (PubMed id 17235323)⁹ Quenneville S.P....Tremblay J.P. (2007)
158. alpha-tocopherol supplementation reduces the elevated 8-hydroxy-2-deoxyguanosine blood levels induced by training in basketball players. (PubMed id 16879069)⁹ Tsakiris S....Schulpis K.H. (2006)
159. Interfacial behavior of cytoplasmic and mitochondrial creatine kinase oligomeric states. (PubMed id 16283667)⁹ Vernoux N....Vial C. (2006)
160. Glucose tolerance and insulin sensitivity following an one-week volleyball competition. (PubMed id 16970246)⁹ Kuo M.C....Kuo C.H. (2006)
161. MicroRNA-1 facilitates skeletal myogenic differentiation without affecting osteoblastic and adipogenic differentiation. (PubMed id 17045567)⁹ Nakajima N....Oh H. (2006)
162. Ectopic expression of a polyalanine expansion mutant of poly(A)-binding protein N1 in muscle cells in culture inhibits myogenesis. (PubMed id 16378590)⁹ Wang Q. and Bag J. (2006)
163. Identification of differentially expressed, tumor-associated proteins in oral squamous cell carcinoma by proteomic analysis. (PubMed id 16568407)⁹ Turhani D....Fountoulakis M. (2006)
164. Overexpression of Rad in muscle worsens diet-induced insulin resistance and glucose intolerance and lowers plasma triglyceride level. (PubMed id 16537411)⁹ Ilany J....Kahn C.R. (2006)
165. Hypertrophy and transcriptional regulation induced in myogenic cell line L6-C5 by an increase of extracellular calcium. (PubMed id 15389566)⁹ De Arcangelis V....Naro F. (2005)
166. Correction of glycogen storage disease type II by an adeno-associated virus vector containing a muscle-specific promoter. (PubMed id 15922959)⁹ Sun B....Koeberl D.D. (2005)
167. A differential proteome in tumors suppressed by an adenovirus-based skin patch vaccine encoding human carcinoembryonic antigen. (PubMed id 15717328)⁹ Huang C.M....Tang D.C. (2005)
168. The role of extrahepatic retinol binding protein in the mobilization of retinoid stores. (PubMed id 15314099)⁹ Quadro L....Colantuoni V. (2004)
169. Laminin alpha2 deficiency and muscular dystrophy; genotype-phenotype correlation in mutant mice. (PubMed id 12609502)⁹ Guo L.T....Engvall E. (2003)
170. Leukocyte-depleted terminal blood cardioplegia provides superior myocardial protective effects in association with myocardium-derived nitric oxide and peroxynitrite production for patients undergoing prolonged aortic crossclamping for more than 120 minutes. (PubMed id 14688692)⁹ Hayashi Y....Matsuda H. (2003)
171. Proteolytic susceptibility of creatine kinase isozyme s and arginine kinase. (PubMed id 12821144)⁹ Ercan A. and Grossman S.H. (2003)
172. Increased creatine kinase and spontaneous activity on electromyography, in amyotrophic lateral sclerosis. (PubMed id 12712806)⁹ Lima A.F....de Carvalho M. (2003)
173. ADAM 12 protease induces adipogenesis in transgenic mice. (PubMed id 12000741)⁹ Kawaguchi N....Wewer U.M. (2002)
174. The coactivator-associated arginine methyltransferase is necessary for muscle differentiation: CARM1 coactivates myocyte enhancer factor-2. (PubMed id 11713257)⁹ Chen S.L....Muscat G.E. (2002)
175. Muscle expression of human retinol-binding protein (RBP). Suppression of the visual defect of RBP knockout mice. (PubMed id 12048218)⁹ Quadro L....Gottesman M.E. (2002)
176. [Establishment of a hemophilia B transgenic mouse mod el on the basis of coagulation factor IX gene knock-out mouse] (PubMed id 12143307)⁹ Che W.L....Fu J.L. (2002)
177. Multiple isoforms and an unusual cathodic isoform of creatine kinase from channel catfish (Ictalurus punctatus). (PubMed id 11587847)⁹ Liu Z....Karsi A. (2001)
178. Muscle-specific promoters may be necessary for adeno- associated virus-mediated gene transfer in the treatment of muscular dystrophie s. (PubMed id 11177557)⁹ Cordier L....Sweeney H.L. (2001)
179. Overexpression of gamma-sarcoglycan induces severe muscular dystrophy. Implications for the regulation of Sarcoglycan assembly. (PubMed id 11287429)⁹ Zhu X....McNally E.M. (2001)
180. Mutagenesis of two acidic active site residues in human muscle creatine kinase: implications for the catalytic mechanism. (PubMed id 11258919)⁹ Cantwell J.S....Babbitt P.C. (2001)
181. Designing gene therapy vectors: avoiding immune respo nses by using tissue-specific promoters. (PubMed id 11821941)⁹ Weeratna R.D....Davis H.L. (2001)
182. Creatine kinase in human retinal pigment epithelium. (PubMed id 10655143)⁹ Kennedy B.G....Mangini N.J. (2000)
183. Interactions between beta-enolase and creatine kinase in the cytosol of skeletal muscle cells. (PubMed id 10657248)⁹ Foucault G....Arrio-Dupont M. (2000)
184. Rescue of skeletal muscles of gamma-sarcoglycan-defic ient mice with adeno-associated virus-mediated gene transfer. (PubMed id 10933922)⁹ Cordier L....Sweeney H.L. (2000)
185. Cardiac fatigue following prolonged endurance exercise of differing distances. (PubMed id 10862531)⁹ Whyte G.P....McKenna W.J. (2000)
186. Isoenzyme-specific interaction of muscle-type creatine kinase with the sarcomeric M-line is mediated by NH(2)-terminal lysine charge-clamps. (PubMed id 10851020)⁹ Hornemann T....Wallimann T. (2000)
187. Lipoprotein lipase-mediated selective uptake from low density lipoprotein requires cell surface proteoglycans and is independent of scavenger receptor class B type 1. (PubMed id 10896681)⁹ Seo T....Deckelbaum R.J. (2000)
188. Presence of enolase in the M-band of skeletal muscle and possible indirect interaction with the cytosolic muscle isoform of creatine kinase. (PubMed id 9931306)⁹ Foucault G....Arrio-Dupont M. (1999)
189. [Brain isoforms of creatine kinase in health and mental diseases: Alzheimer's disease and schizophrenia] (PubMed id 10078058)⁹ Burbaeva G.S.h....Dmitriev A.D. (1999)
190. p38 mitogen-activated protein kinase pathway promotes skeletal muscle differentiation. Participation of the Mef2c transcription factor. (PubMed id 9988769)⁹ Zetser A....Bengal E. (1999)
191. Differential expression and secretion of alpha 1 anti-trypsin between direct DNA injection and implantation of transfected myoblast. (PubMed id 10455404)⁹ Bou-Gharios G....Partridge T. (1999)
192. Lack of requirement for presenilin1 in Notch1 signaling. (PubMed id 10607593)⁹ Berechid B.E....Nye J.S. (1999)
193. [Serum creatine kinase MM isoforms and lactate dehydrogenase isoenzymes in patients with non-traumatic acute rhabdomyolysis] (PubMed id 9522498)⁹ Sanchez Navarro M.R....Oliver Almendros C. (1998)
194. Human smooth muscle alpha-actin gene is a transcriptional target of the p53 tumor suppressor protein. (PubMed id 9546431)⁹ Comer K.A....Kumar C.C. (1998)
195. Protein changes observed in pacing-induced heart failure using two-dimensional electrophoresis. (PubMed id 9740064)⁹ Heinke M.Y....dos Remedios C.G. (1998)
196. Catalytically inactive lipoprotein lipase expression in muscle of transgenic mice increases very low density lipoprotein uptake: direct evidence that lipoprotein lipase bridging occurs in vivo. (PubMed id 9811888)⁹ Merkel M....Breslow J.L. (1998)
197. Constitutively active BMP type I receptors transduce BMP-2 signals without the ligand in C2C12 myoblasts. (PubMed id 9299160)⁹ Akiyama S....Suda T. (1997)
198. Lipoprotein lipase regulates Fc receptor-mediated phagocytosis by macrophages maintained in glucose-deficient medium. (PubMed id 9239412)⁹ Yin B....Goldberg I.J. (1997)
199. Modulation of the specificity and activity of a cellu lar promoter in an adenoviral vector. (PubMed id 9054515)⁹ Shi Q....Worton R. (1997)
200. Prevention of diet-induced obesity in transgenic mice overexpressing skeletal muscle lipoprotein lipase. (PubMed id 9277555)⁹ Jensen D.R....Eckel R.H. (1997)
201. Efficient muscle-specific transgene expression after adenovirus-mediated gene transfer in mice using a 1.35 kb muscle creatine kinase promoter/enhancer. (PubMed id 9274724)⁹ Larochelle N....Nalbantoglu J. (1997)
202. A kinase domain-truncated type I receptor blocks bone morphogenetic protein-2-induced signal transduction in C2C12 myoblasts. (PubMed id 9268344)⁹ Namiki M....Suda T. (1997)
203. High expression of human clotting factor IX cDNA in myoblasts C2C12 cells and C3H mice. (PubMed id 18762876)⁹ Wang H....Xue J. (1997)
204. Sperm function and choice of preparation media: comparison of Percoll and Accudenz discontinuous density gradients. (PubMed id 8833742)⁹ Sbracia M....Huszar G. (1996)
205. Overexpression of myotonic dystrophy kinase in BC3H1 cells induces the skeletal muscle phenotype. (PubMed id 8550617)⁹ Bush E.W....Perryman M.B. (1996)
206. Clinical pharmacokinetics of 3-hydroxy-3-methylglutar yl-coenzyme A reductase inhibitors. (PubMed id 9118584)⁹ Desager J.P. and Horsmans Y. (1996)
207. Human primary myoblast cell cultures from non-diabetic insulin resistant subjects retain defects in insulin action. (PubMed id 8941652)⁹ Thompson D.B....Ossowski V. (1996)
208. Expression of E1A in terminally differentiated muscle cells reactivates the cell cycle and suppresses tissue-specific genes by separable mechanisms. (PubMed id 8816442)⁹ Tiainen M....Crescenzi M. (1996)
209. Construction of human factor IX expression vectors in retroviral vector frames optimized for muscle cells. (PubMed id 8886845)⁹ Wang J.M....Kurachi K. (1996)
210. The effect of eccentric exercise on serum creatine ki nase activity in different ethnic groups. (PubMed id 8836390)⁹ Sherwood R.A....Peters T.J. (1996)
211. MEF2 protein expression, DNA binding specificity and complex composition, and transcriptional activity in muscle and non-muscle cells. (PubMed id 8798771)⁹ Ornatsky O.I. and McDermott J.C. (1996)
212. Muscle wasting and dedifferentiation induced by oxidative stress in a murine model of cachexia is prevented by inhibitors of nitric oxide synthesis and antioxidants. (PubMed id 8617220)⁹ Buck M. and Chojkier M. (1996)
213. A continuous high-resolution physical map spanning 17 megabases of the q12, q13.1, and q13.2 cytogenetic bands of human chromosome 19. (PubMed id 7665184)⁹ Garcia E....Lamerdin J. (1995)
214. Gene for progressive familial heart block type I maps to chromosome 19q13. (PubMed id 7882468)⁹ Brink P.A....Corfield V.A. (1995)
215. Equivalent early sensitivities of myoglobin, creatine kinase MB mass, creatine kinase isoform ratios, and cardiac troponins I and T for acute myocardial infarction. (PubMed id 7656437)⁹ Mair J....Puschendorf B. (1995)
216. A retroviral vector containing a muscle-specific enhancer drives gene expression only in differentiated muscle fibers. (PubMed id 7548273)⁹ Ferrari G....Mavilio F. (1995)
217. Characterization of a murine p53ser246 mutant equivalent to the human p53ser249 associated with hepatocellular carcinoma and aflatoxin exposure. (PubMed id 7605578)⁹ Ghebranious N....Sell S. (1995)
218. Myotonic dystrophy: molecular analysis of Israeli patients. (PubMed id 7858174)⁹ Abeliovich D....Cohen T. (1994)
219. Bone morphogenetic protein-2 converts the differentiation pathway of C2C12 myoblasts into the osteoblast lineage. (PubMed id 7798324)⁹ Katagiri T....Suda T. (1994)
220. Improved quantification with validation of multiple m RNA species by polymerase chain reaction: application to human myocardial creat ine kinase M and B. (PubMed id 8181032)⁹ Ma T.S....Roberts R. (1994)
221. Primary myoblast-mediated gene transfer: persistent expression of human factor IX in mice. (PubMed id 7584074)⁹ Yao S.N....Kurachi K. (1994)
222. Physical and functional interaction between WT1 and p53 proteins. (PubMed id 8389468)⁹ Maheswaran S....Haber D.A. (1993)
223. Identification of DNA-binding protein(s) in the developing heart. (PubMed id 8462740)⁹ Litvin J....Bader D.M. (1993)
224. Fibroblast growth factor inhibits MRF4 activity independently of the phosphorylation status of a conserved threonine residue within the DNA-binding domain. (PubMed id 8413199)⁹ Hardy S....Konieczny S.F. (1993)
225. Overexpression of Id protein inhibits the muscle differentiation program: in vivo association of Id with E2A proteins. (PubMed id 1644289)⁹ Jen Y....Benezra R. (1992)
226. Functional antagonism between c-Jun and MyoD proteins: a direct physical association. (PubMed id 1310896)⁹ Bengal E....Verma I.M. (1992)
227. Identification of MRF4, myogenin, and E12 oligomer complexes by chemical cross-linking and two-dimensional gel electrophoresis. (PubMed id 1311321)⁹ Lin H. and Konieczny S.F. (1992)
228. The human skeletal alpha-actin gene is regulated by a muscle-specific enhancer that binds three nuclear factors. (PubMed id 1633435)⁹ Muscat G.E....Kedes L. (1992)
229. Site-specific binding of wild-type p53 to cellular DNA is inhibited by SV40 T antigen and mutant p53. (PubMed id 1398068)⁹ Bargonetti J....Prives C. (1992)
230. McLeod syndrome: a distinct form of neuroacanthocytos is. Report of two cases and literature review with emphasis on neuromuscular ma nifestations. (PubMed id 1512605)⁹ Witt T.N....Olsen E.G. (1992)
231. Linkage disequilibrium detected between myotonic dyst rophy and the anonymous marker D19S63 in the Spanish population. (PubMed id 1351033)⁹ Cobo A....Baiget M. (1992)
232. 3' creatine kinase (M-type) polymorphisms linked to myotonic dystrophy in Italian and Spanish populations. (PubMed id 1682233)⁹ Gennarelli M....Dallapiccola B. (1991)
233. Immunohistochemical study of childhood rhabdomyosarcomas and related neoplasms. Results of an Intergroup Rhabdomyosarcoma study project. (PubMed id 1710539)⁹ Parham D.M....Maurer H. (1991)
234. Domains outside of the DNA-binding domain impart target gene specificity to myogenin and MRF4. (PubMed id 1658626)⁹ Chakraborty T. and Olson E.N. (1991)
235. Physical and genetic mapping of a novel chromosome 19 ERCC1 marker showing close linkage with myotonic dystrophy. (PubMed id 1674498)⁹ Shutler G....Korneluk R.G. (1991)
236. Isolation and characterization of an avian myogenic cell line. (PubMed id 1985013)⁹ Antin P.B. and Ordahl C.P. (1991)
237. Transforming growth factor beta represses the actions of myogenin through a mechanism independent of DNA binding. (PubMed id 1850837)⁹ Brennan T.J....Olson E.N. (1991)
238. [Application of the polymerase chain reaction technique (PCR) to the molecular diagnosis of myotonic dystrophy] (PubMed id 1687310)⁹ Cobo A.M....Baiget M. (1991)
239. Linkage assignment of a DNA sequence (ERCC2L1) homologous to a human DNA repair gene in Xiphophorus fishes: implications for the evolutionary derivation of human chromosome 19. (PubMed id 1680795)⁹ Walter R.B....Nairn R.S. (1991)
240. MyoD binds cooperatively to two sites in a target enhancer sequence: occupancy of two sites is required for activation. (PubMed id 2377600)⁹ Weintraub H....Lassar A. (1990)
241. Linkage relationships of the apolipoprotein C1 gene and a cytochrome P450 gene (CYP2A) to myotonic dystrophy. (PubMed id 1975560)⁹ Walsh K.V....Shaw D.J. (1990)
242. Direct haplotyping by double digestion of PCR-amplified creatine kinase (CKMM): application to myotonic dystrophy diagnosis. (PubMed id 1980487)⁹ Lavedan C....Junien C. (1990)
243. Presymptomatic and prenatal diagnosis in myotonic dys trophy by genetic linkage studies. (PubMed id 2320244)⁹ Speer M.C....Roses A.D. (1990)
244. Establishment of the mouse chromosome 7 region with homology to the myotonic dystrophy region of human chromosome 19q. (PubMed id 1970795)⁹ Cavanna J.S....Brown S.D. (1990)
245. [Dystrophia myotonica (Steinert disease)--a frequentl y misdiagnosed disease] (PubMed id 2198475)⁹ Kuhn E....RA1del R. (1990)

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