CKAP5 Gene
protein-coding GIFtS: 57
GCID: GC11M048068
|
|
cytoskeleton associated protein 5
| |
Aliases
for CKAP5 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| Cytoskeleton Associated Protein 51 2 | | MSPS2 5 | | KIAA00971 3 5 | | Colonic And Hepatic Tumor Over-Expressed Gene Protein2 | | TOG1 2 | | Cytoskeleton-Associated Protein 52 | | TOGp1 2 | | Ch-TOG3 | | Ch-TOG3 | | EC 2.7.7.68 | | Colonic And Hepatic Tumor Overexpressed Gene Protein2 3 | | EC 3.1.1.298 | | CHTOG2 5 | | |
Export aliases for CKAP5 gene to outside databasesPrevious GC identifers: GC11M046722 GC11M046470 GC11M046815 |
Summaries
for CKAP5 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for CKAP5:
This gene encodes a cytoskeleton-associated protein which belongs to the TOG/XMAP215 family. The N-terminal half ofthis protein contains a microtubule-binding domain and the C-terminal half contains a KXGS motif for binding tubulindimers. This protein has two distinct roles in spindle formation; it protects kinetochore microtubules fromdepolymerization and plays an essential role in centrosomal microtubule assembly. This protein may be necessary forthe proper interaction of microtubules with the cell cortex for directional cell movement. It also plays a role intranslation of the myelin basic protein (MBP) mRNA by interacting with heterogeneous nuclear ribonucleoprotein (hnRNP)A2, which associates with MBP. Alternatively spliced transcript variants encoding different isoforms have beenidentified. (provided by RefSeq, Aug 2011)
UniProtKB/Swiss-Prot: CKAP5_HUMAN, Q14008Function: Binds to the plus end of microtubules and regulates microtubule dynamics and microtubule organization.Promotes cytoplasmic microtubule nucleation and elongation. Plays a major role in organizing spindle poles
Gene Wiki entry for CKAP5
|
Genomic Views
for CKAP5 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000011.9 NC_018922.1 NT_009237.18
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the CKAP5 gene promoter:
NF-1 AML1a Lmo2 CUTL1 HEN1 Egr-2 E2F-1 E2F Zic3 Pax-4a
Other transcription factors
Search SABiosciences Chromatin IP Primers for CKAP5
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CKAP5 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 11p11.2 Ensembl cytogenetic band: 11p11.2 HGNC cytogenetic band: 11p11.2CKAP5 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 11 GeneLoc Exon Structure GeneLoc location for GC11M048068: view genomic region
(about GC identifiers)
Start:
|
46,764,598 bp from pter |
End:
|
46,867,847 bp from pter |
Size:
|
103,250 bases |
Orientation:
|
minus strand |
|
Proteins
for CKAP5 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: CKAP5_HUMAN, Q14008 (See
protein sequence)Recommended Name: Cytoskeleton-associated protein 5 Size: 2032 amino acids; 225495 Da
Subunit: Interacts with TACC1. Interacts with SLAIN2
Subcellular location: Cytoplasm, cytoskeleton, centrosome. Cytoplasm, cytoskeleton, spindle pole. Note=Detected oncentrosomes during interphase. Detected on spindle poles and microtubules during mitosis
Sequence caution: Sequence=AAH17856.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential poly-Asequence; Sequence=AAH70136.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential poly-A sequence;Sequence=AAI11044.1; Type=Miscellaneous discrepancy; Note=Contaminating sequence. Potential poly-A sequence;Sequence=AAI20871.1; Type=Frameshift; Positions=18; Sequence=BAA07892.2; Type=Erroneous initiation;
Secondary accessions: Q05D70 Q0VAX7 Q0VAX8 Q14668 Q2TA89 Q6NSH4Alternative splicing: 3 isoforms: Q14008-1 Q14008-2 Q14008-3 (No experimental confirmation available)Explore the universe of human proteins at neXtProt for CKAP5: NX_Q14008
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q14008
2 DME Specific Peptides for CKAP5 (Q14008)
CKAP5 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins (2 alternative transcripts):
NP_001008938.1 NP_055571.2
ENSEMBL proteins: ENSP00000432768 ENSP00000346566 ENSP00000434523 ENSP00000431509 ENSP00000436052 ENSP00000436769 ENSP00000395302 ENSP00000310227 Reactome Protein details: Q14008
Human Recombinant Protein Products:
Gene Ontology (GO): 5/7 cellular component terms (GO ID links to tree view) (see all 7): About this table
CKAP5 for ontologies About GeneDecksing
CKAP5 Antibody Products:
Assay Products for CKAP5: |
Protein
Domains /
Families
for CKAP5 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
CKAP5 for domains About GeneDecksing
5 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q14008ProtoNet protein and cluster: Q14008 1 Blocks protein family: IPB000357 HEAT repeat
UniProtKB/Swiss-Prot: CKAP5_HUMAN, Q14008Similarity: Belongs to the TOG/XMAP215 familySimilarity: Contains 10 HEAT repeats |
Function
for CKAP5 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase
shRNA from
OriGene,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Function Summary:
UniProtKB/Swiss-Prot: CKAP5_HUMAN, Q14008Function: Binds to the plus end of microtubules and regulates microtubule dynamics and microtubule organization.Promotes cytoplasmic microtubule nucleation and elongation. Plays a major role in organizing spindle polesEnzyme Numbers (IUBMB): EC 2.7.7.62 EC 3.1.1.292
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CKAP5 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CKAP5 (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling 
| |  | GenScript: all cDNA clones in your preferred vector (see all 2): CKAP5 (NM_001008938) | |  | Browse Sino Biological Human cDNA Clones | |  | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CKAP5 | |  | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CKAP5 |
In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CKAP5 |
Gene Ontology (GO): 1 molecular function term (GO ID links to tree view): About this table
CKAP5 for ontologies About GeneDecksing
10 GenomeRNAi human phenotypes for CKAP5:
Animal Models:
3 MGI mutant phenotypes (inferred from 1 allele ) (MGI details for Ckap5):
CKAP5 for phenotypes About GeneDecksing
|
Pathways & Interactions
for CKAP5 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Unified GeneCards pathways About this table
See pathways by source
| Super-pathway | contained gene-specific pathways |
|---|
| 1 | Recruitment of mitotic centrosome proteins and complexes | | | 2 | M Phase | | | 3 | Resolution of Sister Chromatid Cohesion | | | 4 | Cell Cycle | | | 5 | Aurora A signaling | |
Pathway sources
See GeneCards unified pathways
Show all pathways
1  BioSystems Pathway for CKAP5
5/16 
Reactome Pathways for CKAP5 (see all 16)
CKAP5 for pathways About GeneDecksing
Interactions:
SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for CKAP5
STRING Interaction
Network Preview (showing 5 interactants - click image to see 25)
5/874 Interacting proteins for CKAP5 (Q140081, 2, 3 ENSP000003465664) via UniProtKB, MINT, STRING, and/or I2D (see all 874)| Interactant | Interaction Details |
|---|
| GeneCard | External ID(s) |
|---|
| TACC3 | Q9Y6A52, 3, ENSP000003265504 | MINT-8145000 MINT-8144928 MINT-8144977 MINT-8145261 MINT-8145016 MINT-8145273 I2D:
score=3 STRING: ENSP00000326550 | | SNW1 | Q135732, 3, ENSP000002615314 | MINT-7945693 MINT-7947479 I2D:
score=2 STRING: ENSP00000261531 | | NCK1 | P163331, 3, ENSP000002889864 | EBI-310585,EBI-3448658 I2D:
score=1 STRING: ENSP00000288986 | | CDK9 | P507502, 3, ENSP000003623614 | MINT-7945693 MINT-7947479 I2D:
score=1 STRING: ENSP00000362361 | | CLTA | P094962, ENSP000002422854 | MINT-8144928 MINT-8145261 MINT-8145273 STRING: ENSP00000242285 |
About this table
Gene Ontology (GO): 5/9 biological process terms (GO ID links to tree view) (see all 9): About this table
CKAP5 for ontologies About GeneDecksing
|
Drugs & Compounds
for CKAP5 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for CKAP5
Search CenterWatch for drugs/clinical trials and news about CKAP5
|
Transcripts
for CKAP5 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for CKAP5 gene (2 alternative transcripts): NM_001008938.3 NM_014756.3 Unigene Cluster for CKAP5: Cytoskeleton associated protein 5 Hs.201253 [show with all ESTs]Unigene Representative Sequence: NM_00100893813 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000529230(uc001ndh.1) ENST00000354558 ENST00000533413 ENST00000525896
ENST00000527333 ENST00000526876 ENST00000526943 ENST00000528593 ENST00000532321
ENST00000526496 ENST00000525248 ENST00000415402(uc009ylg.1 uc001ndi.2)
ENST00000312055(uc001ndj.2)
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CKAP5 (see all 4)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CKAP5 (see all 3)
OriGene custom cloning services – gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector (see all 2): CKAP5 (NM_001008938) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CKAP5 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CKAP5 |
Additional cDNA sequence: BC017856.1 BC035554.1 BC070136.1 BC111043.1 BC120869.1 BC120870.1 D43948.1 X92474.1 17 DOTS entries: DT.218700 DT.92326973 DT.95371188 DT.120702319 DT.120702300 DT.95360204 DT.100818315 DT.100687634 DT.120702250 DT.95371190 DT.75141786 DT.100725564 DT.40116371 DT.40132583 DT.91755028 DT.95194757 DT.95202523 24/401 AceView cDNA sequences (see all 401): CD644630 R53724 BG286993 BF934939 BU956431 BE857729 AA776435 BQ709475 AA401741 CA434083 W94958 BF970763 BQ432517 BM833010 BE736081 BG257990 BM552797 CR623748 BX406423 BG397030 CD643756 CF786005 AI817814 BU428719
GeneLoc Exon Structure
5/8 Alternative Splicing Database (ASD) splice patterns (SP) for CKAP5 (see all 8) About this scheme
| ExUns: | 1 | ^ | 2 | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9 | ^ | 10 | ^ | 11 | ^ | 12 | ^ | 13 | ^ | 14 | ^ | 15 | ^ | 16 | ^ | 17 | ^ | 18 | ^ | 19 | ^ | 20a | · | 20b | ^ | 21 | ^ | 22 | ^ | 23a | · | 23b | ^ | 24a | · |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | - | | | | | |
| ExUns: | 24b | ^ | 25 | ^ | 26a | · | 26b | ^ | 27 | ^ | 28 | ^ | 29 | ^ | 30a | · | 30b | ^ | 31 | ^ | 32 | ^ | 33 | ^ | 34 | ^ | 35 | ^ | 36 | ^ | 37 | ^ | 38 | ^ | 39 | ^ | 40 | ^ | 41 |
|---|
|
| SP1: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP2: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP3: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP4: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
| SP5: | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | | |
ECgene alternative splicing isoforms for CKAP5
|
Expression
for CKAP5 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| CKAP5 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: ATACAACTAA
About this image
See CKAP5 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for CKAP5
SOURCE GeneReport for Unigene cluster: Hs.201253
UniProtKB/Swiss-Prot: CKAP5_HUMAN, Q14008Tissue specificity: Overexpressed in hepatomas and colonic tumors. Also expressed in skeletal muscle, brain, heart,placenta, lung, liver, kidney and pancreas
SABiosciences Custom PCR Arrays for CKAP5
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CKAP5
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat CKAP5 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CKAP5 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CKAP5 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CKAP5 |
Orthologs
for CKAP5 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for CKAP5 gene from 9/30 species (see all 30) About this table
ENSEMBL Gene Tree for CKAP5 (if available)
TreeFam Gene Tree for CKAP5 (if available) |
Paralogs
for CKAP5 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| -- |
Genomic Variants
for CKAP5 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 11 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for CKAP5 (46764598 - 46867847 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV) variations for CKAP5: -- | SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CKAP5 |
|
Disorders
/ Diseases
for CKAP5 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
CKAP5 for disorders About GeneDecksing
OMIM gene information: 611142
OMIM disorders: --
10  diseases for CKAP5: About MalaCardssudden infant death syndrome hepatitis lactic acidosis cerebrovascular accident
melas syndrome acrocephalosyndactylia macular degeneration leigh disease
breast cancer ataxia
1 disease from the University of Copenhagen DISEASES database for CKAP5:Sudden infant death syndrome Human Genome Epidemiology (HuGE) Navigator: CKAP5 (2 documents)
Export disorders for CKAP5 gene to outside databases
|
Publications
for CKAP5 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for CKAP5 gene, integrated from 9 sources (see all 54):
(articles sorted by number of sources associating them with CKAP5) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- Characterization of the cDNA and pattern of expression of a new gene over-expressed in human hepatomas and colonic tumors. (PubMed id 8536682)1, 2, 3 Charrasse S.... Larroque C. (1995)
- Prediction of the coding sequences of unidentified human genes. III. The coding sequences of 40 new genes (KIAA0081-KIAA0120) deduced by analysis of cDNA clones from human cell line KG-1. (PubMed id 7788527)1, 2, 3 Nagase T....Kotani H. (1995)
- The ch-TOG/XMAP215 protein is essential for spindle pole organization in human somatic cells. (PubMed id 12569123)1, 2 Gergely F.... Raff J.W. (2003)
- Interaction of the transforming acidic coiled-coil 1 (TACC1) protein with ch-TOG and GAS41/NuBI1 suggests multiple TACC1-containing protein complexes in human cells. (PubMed id 11903063)1, 2 Lauffart B.... Still I.H. (2002)
- Aurora-A and ch-TOG act in a common pathway in control of spindle pole integrity. (PubMed id 18663358)1, 9 De Luca M....Guarguaglini G. (2008)
- TACC1-chTOG-Aurora A protein complex in breast cancer. (PubMed id 14603251)1, 9 Conte N.... Birnbaum D. (2003)
- Clathrin promotes centrosome integrity in early mitosi s through stabilization of centrosomal ch-TOG. (PubMed id 22891263)1 Foraker A.B....Brodsky F.M. (2012)
- Systematic survey of deubiquitinase localization ident ifies USP21 as a regulator of centrosome- and microtubule-associated functions. (PubMed id 22298430)1 Urbe S....Clague M.J. (2012)
- Functional dissection of lysine deacetylases reveals t hat HDAC1 and p300 regulate AMPK. (PubMed id 22318606)1 Lin Y.Y....Boeke J.D. (2012)
- Targeted ubiquitination and degradation of G-protein-c oupled receptor kinase 5 by the DDB1-CUL4 ubiquitin ligase complex. (PubMed id 22952844)1 Wu Z....Ma L. (2012)
|
External Searches for CKAP5 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing CKAP5 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing CKAP5 gene
(According to HUGE)
About This Section
| |
Specialized Databases showing CKAP5 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for CKAP5 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for CKAP5 gene:
Search GeneIP for patents involving CKAP5
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for CKAP5 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences),
In Situ Hybridization Assays from
Advanced Cell Diagnostics
About This Section
|
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| | |  | OriGene Antibodies for CKAP5 | | OriGene shRNA RFP for CKAP5 | | | OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CKAP5 | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CKAP5 | | | Browse OriGene Protein Over-expression Lysates | | Browse OriGene Fluorogenic Cell Assay Kits | | | Browse OriGene siRNAs | | OriGene 3'-UTR Clone for CKAP5 | | | OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CKAP5 | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CKAP5 | | | Browse OriGene GFP tagged cDNA clones in CMV expression vector | | Browse OriGene MicroRNA Expression Plasmids | | | Browse OriGene basic RS shRNAs | | Browse OriGene validated miRNA SYBR primer pairs | | | Browse OriGene full length recombinant human proteins expressed in human HEK293 cells | | OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling | | | OriGene Custom Antibody Services for CKAP5 | | OriGene Custom Protein Services for CKAP5 | | | OriGene Custom Immunoassay Development | | |
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| | | QIAGEN Custom miScript Target Protector blocks miRNA-binding site of in human, mouse, rat CKAP5 | | | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CKAP5 | | | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CKAP5 | | | QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CKAP5 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CKAP5 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CKAP5 |
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| | | | Search Tocris compounds for CKAP5 |
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 | | | CKAP5 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CKAP5 |
|  |  |  | | | | ThermoFisher Antibodies for CKAP5 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CKAP5 |
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