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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

CIZ1 Gene

protein-coding   GIFtS: 55
GCID: GC09M130929

CDKN1A Interacting Zinc Finger Protein 1

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(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
CDKN1A Interacting Zinc Finger Protein 11 2     NP942 3
Nuclear Protein NP942 3     ZNF3562 3
Zinc Finger Protein 3562 3     Cip1-Interacting Zinc Finger Protein2
LSFR12 3     CDKN1A-Interacting Zinc Finger Protein 13

External Ids:    HGNC: 167441   Entrez Gene: 257922   Ensembl: ENSG000001483377   OMIM: 6114205   UniProtKB: Q9ULV33   

Export aliases for CIZ1 gene to outside databases

Previous GC identifers: GC09M122043 GC09M122574 GC09M124382 GC09M126304 GC09M128007 GC09M129968 GC09M100541


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for CIZ1 Gene:
The protein encoded by this gene is a zinc finger DNA binding protein that interacts with CIP1, part of a complex
with cyclin E. The encoded protein may regulate the cellular localization of CIP1. Several transcript variants
encoding different isoforms have been found for this gene. (provided by RefSeq, Apr 2012)

GeneCards Summary for CIZ1 Gene: 
CIZ1 (CDKN1A interacting zinc finger protein 1) is a protein-coding gene. Diseases associated with CIZ1 include cervical dystonia, and cervicitis. GO annotations related to this gene include cyclin binding and nucleic acid binding.

UniProtKB/Swiss-Prot: CIZ1_HUMAN, Q9ULV3
Function: May regulate the subcellular localization of CIP/WAF1

Gene Wiki entry for CIZ1 Gene


(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000009.11  NT_008470.19  NC_018920.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the CIZ1 gene promoter:
         AP-2alpha isoform 3   AP-1   AP-2alpha isoform 2   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 4): CIZ1 promoter sequence
   Search SABiosciences Chromatin IP Primers for CIZ1

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CIZ1


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 9q34.1   Ensembl cytogenetic band:  9q34.11   HGNC cytogenetic band: 9q34.1

CIZ1 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CIZ1 gene location

GeneLoc information about chromosome 9         GeneLoc Exon Structure

GeneLoc location for GC09M130929:  view genomic region     (about GC identifiers)

Start:
130,928,343 bp from pter      End:
130,966,662 bp from pter
Size:
38,320 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: CIZ1_HUMAN, Q9ULV3 (See protein sequence)
Recommended Name: Cip1-interacting zinc finger protein  
Size: 898 amino acids; 100045 Da
Subunit: Interacts with CIP/WAF1
Subcellular location: Nucleus
Sequence caution: Sequence=AAF23231.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Sequence=AAF37882.1; Type=Erroneous initiation; Note=Translation N-terminally extended;
Secondary accessions: A8K9J8 B4E131 B7ZAS8 Q5SYW3 Q5SYW5 Q8WU72 Q9H868 Q9NYM8 Q9UHK4 Q9Y3F9
Q9Y3G0
Alternative splicing: 5 isoforms:  Q9ULV3-1   Q9ULV3-2   Q9ULV3-3   Q9ULV3-4   Q9ULV3-5   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for CIZ1: NX_Q9ULV3

Explore proteomics data for CIZ1 at MOPED 

Post-translational modifications:

  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q9ULV3

  • CIZ1 Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    CIZ1 Protein Expression
    REFSEQ proteins (7 alternative transcripts): 
    NP_001124487.1  NP_001124488.1  NP_001124489.1  NP_001124490.1  NP_001244904.1  NP_001244905.1  NP_036259.2  

    ENSEMBL proteins: 
     ENSP00000362045   ENSP00000277465   ENSP00000362039   ENSP00000362029   ENSP00000398011  
     ENSP00000321780   ENSP00000407265   ENSP00000377232   ENSP00000439244   ENSP00000350169  
     ENSP00000320374   ENSP00000445057  

    Human Recombinant Protein Products for CIZ1: 
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    Novus Biologicals CIZ1 Protein
    Novus Biologicals CIZ1 Lysates
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates 
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for CIZ1 

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IEA--

    CIZ1 for ontologies           About GeneDecksing



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    Cloud-Clone Corp. CLIAs for CIZ1


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    5/6 InterPro protein domains (see all 6):
     IPR003604 Znf_U1
     IPR026811 CIZ1
     IPR015880 Znf_C2H2-like
     IPR000690 Znf_C2H2_matrin
     IPR007087 Znf_C2H2

    Graphical View of Domain Structure for InterPro Entry Q9ULV3

    ProtoNet protein and cluster: Q9ULV3

    1 Blocks protein domain: IPB003604 Zn-finger

    UniProtKB/Swiss-Prot: CIZ1_HUMAN, Q9ULV3
    Similarity: Contains 1 matrin-type zinc finger


    CIZ1 for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: CIZ1_HUMAN, Q9ULV3
    Function: May regulate the subcellular localization of CIP/WAF1

         Genatlas biochemistry entry for CIZ1:
    CIP1 (CDKN1A interacting zinc finger protein 1,linked to surfeit gene in Fugu rubripes homolog 1

         Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003676nucleic acid binding IEA--
    GO:0005515protein binding IPI18654987
    GO:0008270zinc ion binding IEA--
    GO:0030332cyclin binding IEA--
         
    CIZ1 for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for CIZ1:
     Actin fiber cells 

    Animal Models:
       inGenious Targeting Laboratory - Custom generated mouse model solutions for CIZ1 
       inGenious Targeting Laboratory - Custom generated inducible mouse model solutions for CIZ1

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for CIZ1 
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    hsa-miR-1290 hsa-miR-548am hsa-miR-548d-3p hsa-miR-548x
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
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    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CIZ1


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section



    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for CIZ1

    STRING Interaction Network Preview (showing 4 interactants - click image to see more details)

    4 Interacting proteins for CIZ1 (Q9ULV31, 3 ENSP000003620294) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    SH3BP4Q9P0V31, 3, ENSP000003402374EBI-2652948,EBI-1049513 I2D: score=1 STRING: ENSP00000340237
    MAP1LC3AQ9H4923, ENSP000003639704I2D: score=1 STRING: ENSP00000363970
    CDKN1AP389363, ENSP000002447414I2D: score=3 STRING: ENSP00000244741
    SH3KBP1ENSP000003809214STRING: ENSP00000380921
    About this table

    Gene Ontology (GO): 2 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0032298positive regulation of DNA-dependent DNA replication initiation IEA--
    GO:0051658maintenance of nucleus location IEA--

    CIZ1 for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for CIZ1

    Search CenterWatch for drugs/clinical trials and news about CIZ1

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for CIZ1 gene (7 alternative transcripts): 
    NM_001131015.1  NM_001131016.1  NM_001131017.1  NM_001131018.1  NM_001257975.1  NM_001257976.1  NM_012127.2  

    Unigene Cluster for CIZ1:

    CDKN1A interacting zinc finger protein 1
    Hs.212395  [show with all ESTs]
    Unigene Representative Sequence: AK124335
    18/27 Ensembl transcripts including schematic representations, and UCSC links where relevant (see all 27):
    ENST00000471773 ENST00000485862 ENST00000372954 ENST00000461765 ENST00000277465
    ENST00000372948 ENST00000372938(uc004btt.3 uc011mar.2 uc004btx.2)
    ENST00000415526 ENST00000471839 ENST00000491487 ENST00000485001 ENST00000476727
    ENST00000476541 ENST00000475471 ENST00000476239 ENST00000488559 ENST00000467178
    ENST00000491954

    miRNA
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    4 QIAGEN miScript miRNA Assays for microRNAs that regulate CIZ1:
    hsa-miR-1290 hsa-miR-548am hsa-miR-548d-3p hsa-miR-548x
    Browse SwitchGear 3'UTR luciferase reporter plasmids
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene RNAi products in human, mouse, rat for CIZ1
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CIZ1
    Clone
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    OriGene clones in human, mouse for CIZ1 (see all 25)
    OriGene ORF clones in mouse, rat for CIZ1
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CIZ1
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    Additional mRNA sequence: 

    AB030835.1 AF159025.1 AF234161.1 AK023978.1 AK027287.1 AK124335.1 AK292713.1 AK296363.1 
    AK303288.1 AK303636.1 AK316393.1 BC004119.2 BC021163.2 EF441870.1 

    24/40 DOTS entries (see all 40):

    DT.92451828  DT.100655683  DT.95123933  DT.97864528  DT.121189874  DT.100655681  DT.95143880  DT.100867189 
    DT.97824706  DT.92451819  DT.100655688  DT.121189848  DT.92324446  DT.100044893  DT.101961599  DT.91831541 
    DT.97864529  DT.121189819  DT.100864080  DT.100655684  DT.121189780  DT.121189727  DT.121189802  DT.97864526 

    24/653 AceView cDNA sequences (see all 653):

    BU617131 BM743935 BQ574497 AW083124 AI193185 BX415165 BM773107 AI458733 
    BE792354 BU191575 CD671840 BM767076 BM728529 BM742449 CB143798 BU517010 
    BM757318 BM767107 BI115272 BE502629 BM462154 AA054741 CA308534 AI018349 

    GeneLoc Exon Structure

    5/17 Alternative Splicing Database (ASD) splice patterns (SP) for CIZ1 (see all 17)    About this scheme

    ExUns: 1 ^ 2a · 2b · 2c ^ 3 ^ 4a · 4b · 4c · 4d ^ 5a · 5b · 5c ^ 6 ^ 7 ^ 8a · 8b · 8c · 8d · 8e · 8f ^ 9a · 9b · 9c · 9d · 9e ^ 10 ^
    SP1:        -                 -                                                                                               -     -     -     -     -     -   
    SP2:                                                                                                                                                            
    SP3:        -                                                                                                                                                   
    SP4:        -                                               -                                                                                                   
    SP5:        -     -     -     -                                                                                                                                 

    ExUns: 11a · 11b ^ 12 ^ 13 ^ 14 ^ 15a · 15b · 15c · 15d ^ 16a · 16b ^ 17a · 17b ^ 18a · 18b · 18c
    SP1:  -     -     -     -     -     -     -     -     -     -     -     -                           
    SP2:                                                                                                
    SP3:                                                                                                
    SP4:                                                                                                
    SP5:                                                                                                


    ECgene alternative splicing isoforms for CIZ1

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    CIZ1 expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TTTTTACTCA
    CIZ1 Expression
    About this image


    See CIZ1 Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for CIZ1

    SOURCE GeneReport for Unigene cluster: Hs.212395
        SABiosciences Custom PCR Arrays for CIZ1
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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CIZ1

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for CIZ1 gene from 4/10 species (see all 10)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Ciz11 , 5 CDKN1A interacting zinc finger protein 11, 5 78.73(n)1
    72.12(a)1
      2 (22.09 cM)5
    683791  NM_028412.21  NP_082688.11 
     323523275 
    lizard
    (Anolis carolinensis)
    Reptilia CIZ16
    Uncharacterized protein
    38(a)
    1 ↔ 1
    GL343763.1(174930-197547)
    African clawed frog
    (Xenopus laevis)
    Amphibia Xl.188152 Xenopus laevis transcribed sequence with moderate similarity more 82.65(n)    BI446667.1 
    zebrafish
    (Danio rerio)
    Actinopterygii wufi27d022 Danio rerio cDNA clone MGC66467 IMAGE2600996, complete more 74.45(n)    BC055672.1 


    ENSEMBL Gene Tree for CIZ1 (if available)
    TreeFam Gene Tree for CIZ1 (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for CIZ1 gene
    1 SIMAP similar gene for CIZ1 using alignment to 7 protein entries:     CIZ1_HUMAN (see all proteins):
    LSFR1

    CIZ1 for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/879 SNPs in CIZ1 are shown (see all 879)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 9 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    VAR_0679744
    ----see VAR_0679742 Q E mis40--------
    VAR_0679764
    ----see VAR_0679762 R M mis40--------
    VAR_0679734
    ----see VAR_0679732 S G mis40--------
    VAR_0679724
    ----see VAR_0679722 P L mis40--------
    VAR_0679754
    ----see VAR_0679752 S F mis40--------
    VAR_0679714
    ----see VAR_0679712 P S mis40--------
    rs2011119631,2
    --130932396(+) ATGAC-/AACAGTC 7 -- int10--------
    rs1446992231,2
    C--130932397(+) TGACA-/ACAGTCA 7 -- int10--------
    rs352831921,2
    C,F--130932398(+) TGACA-/AC/CA 
            
    AGTCA
    7 -- int15NS 180
    rs592322581,2
    C--130932398(+) GACAA-/CAGTCAA 7 -- int12Minor allele frequency- CA:0.25NA 4

    HapMap Linkage Disequilibrium report for CIZ1 (130928343 - 130966662 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for CIZ1:    About this table     
    Variant IDTypeSubtypePubMed ID
    dgv8294n71CNV Loss21882294
    nsv893891CNV Loss21882294
    nsv893859CNV Loss21882294
    nsv893894CNV Gain21882294


    Human Gene Mutation Database (HGMD): CIZ1
    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing CIZ1
    DNA2.0 Custom Variant and Variant Library Synthesis for CIZ1

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 611420    OMIM disorders: --

    UniProtKB/Swiss-Prot: CIZ1_HUMAN, Q9ULV3
  • Note=Defects in CIZ1 may be a cause of adult onset primary cervical dystonia. Dystonia is defined by the
    presence of sustained involuntary muscle contractions, often leading to abnormal postures. Cervical dystonia or
    spasmodic torticollis, the most common form of focal dystonia, is characterized by involuntary contractions of
    the neck muscles, which produce abnormal posturing of the head upon the trunk

  • 7 diseases for CIZ1:    About MalaCards
    cervical dystonia    cervicitis    pancreatic cancer    alzheimer's disease
    pancreatitis    gastric cancer    lung cancer


    CIZ1 for disorders           About GeneDecksing


    Congresses - knowledge worth sharing:  
    Alzheimer's & Parkinson's Diseases Congress (ADPD) 18 - 22 March 2015

    Export disorders for CIZ1 gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for CIZ1 gene, integrated from 9 sources (see all 26):
    (articles sorted by number of sources associating them with CIZ1)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Cloning and characterization of a novel p21(Cip1/Waf1)-interacting zinc finger protein, ciz1. (PubMed id 10529385)1, 2, 3, 9 Mitsui K.... Yoshimura A. (1999)
    2. Ciz1, Cip1 interacting zinc finger protein 1 binds the consensus DNA sequence ARYSR(0-2)YYAC. (PubMed id 12824700)1, 2, 9 Warder D.E. and Keherly M.J. (2003)
    3. Mutations in CIZ1 cause adult onset primary cervical dystonia. (PubMed id 22447717)1, 2 Xiao J....Ledoux M.S. (2012)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    5. Extensive gene order differences within regions of conserved synteny between the Fugu and human genomes: implications for chromosomal evolution and the cloning of disease genes. (PubMed id 10369878)1, 2 Gilley J. and Fried M. (1999)
    6. Cancer-associated missplicing of exon 4 influences the subnuclear distribution of the DNA replication factor CIZ1. (PubMed id 17508423)1, 9 Rahman F.A....Coverley D. (2007)
    7. Altered splicing in exon 8 of the DNA replication factor CIZ1 affects subnuclear distribution and is associated with Alzheimer's disease. (PubMed id 18583151)1, 9 Dahmcke C.M....Mitchelmore C. (2008)
    8. Identification and functional analysis of the erh1(+) gene encoding enhancer of rudimentary homolog from the fission yeast Schizosacch aromyces pombe. (PubMed id 23145069)1 Krzyzanowski M.K....Kozlowski P. (2012)
    9. Variant Ciz1 is a circulating biomarker for early-stag e lung cancer. (PubMed id 23074256)1 Higgins G....Coverley D. (2012)
    10. A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
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      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 25792 HGNC: 16744 AceView: CIZ1 Ensembl:ENSG00000148337 euGenes: HUgn25792
    ECgene: CIZ1 H-InvDB: CIZ1

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for CIZ1 Pharmacogenomics, SNPs, Pathways
    NIEHS-SNPshttp://egp.gs.washington.edu/data/ciz1/

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for CIZ1 gene:
    Search GeneIP for patents involving CIZ1

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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