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CITED4 Gene

protein-coding   GIFtS: 44
GCID: GC01M041362

Cbp/P300-Interacting Transactivator, With Glu/Asp-Rich Carboxy-Terminal...

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
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Aliases
Cbp/P300-Interacting Transactivator, With Glu/Asp-Rich Carboxy-Terminal
Domain, 41 2
Transcriptional Co-Activator 41 2
MRG-22 3
MSG1-Related Protein 22 3
Cbp/P300-Interacting Transactivator 42
MRG23

External Ids:    HGNC: 186961   Entrez Gene: 1637322   Ensembl: ENSG000001798627   OMIM: 6068155   UniProtKB: Q96RK13   

Export aliases for CITED4 gene to outside databases

Previous GC identifers: GC01M040330 GC01M040790 GC01M040740 GC01M040995 GC01M041099 GC01M039444


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
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Entrez Gene summary for CITED4 Gene:
The protein encoded by this intronless gene belongs to the CITED family of transcriptional coactivators that bind
to several proteins, including CREB-binding protein (CBP) and p300, via a conserved 32 aa C-terminal motif, and
regulate gene transcription. This protein also interacts with transcription factor AP2 (TFAP2), and thus may
function as a co-activator for TFAP2. Hypermethylation and transcriptional downregulation of this gene has been
observed in oligodendroglial tumors with deletions of chromosomal arms 1p and 19q, and associated with longer
recurrence-free and overall survival of patients with oligodendroglial tumors. (provided by RefSeq, Aug 2011)

GeneCards Summary for CITED4 Gene:
CITED4 (Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4) is a protein-coding gene. Diseases associated with CITED4 include hypoxia, and endotheliitis. GO annotations related to this gene include transcription coactivator activity. An important paralog of this gene is CITED1.

UniProtKB/Swiss-Prot: CITE4_HUMAN, Q96RK1
Function: Acts as transcriptional coactivator for TFAP2/AP-2. Enhances estrogen-dependent transactivation mediated
by estrogen receptors. May function as an inhibitor of transactivation by HIF1A by disrupting HIF1A interaction
with CREBBP. May be involved in regulation of gene expression during development and differentiation of blood
cells, endothelial cells and mammary epithelial cells




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
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RefSeq DNA sequence:
NC_000001.11  NC_018912.2  NT_032977.10  
Regulatory elements:
   Regulatory transcription factor binding sites in the CITED4 gene promoter:
         HOXA9B   HOXA9   GATA-3   AP-2alpha isoform 3   AP-2alpha isoform 2   GATA-2   GATA-1   AP-2alpha isoform 4   AP-2alpha   AP-2alphaA   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmidCITED4 promoter sequence
   Search Chromatin IP Primers for CITED4

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat CITED4


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 1p34.2|1p35-p34   Ensembl cytogenetic band:  1p34.2   HGNC cytogenetic band: 1p34.1

CITED4 Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CITED4 gene location

GeneLoc information about chromosome 1         GeneLoc Exon Structure

GeneLoc location for GC01M041362:  view genomic region     (about GC identifiers)

Start:
41,326,728 bp from pter      End:
41,328,018 bp from pter
Size:
1,291 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
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UniProtKB/Swiss-Prot: CITE4_HUMAN, Q96RK1 (See protein sequence)
Recommended Name: Cbp/p300-interacting transactivator 4  
Size: 184 amino acids; 18569 Da
Subunit: Interacts via its C-terminal region with the CH1 domain of CREBBP and EP300. Interacts with all
TFAP2/AP-2 isoforms

Explore the universe of human proteins at neXtProt for CITED4: NX_Q96RK1

Explore proteomics data for CITED4 at MOPED


See CITED4 Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

REFSEQ proteins: NP_597724.1  
ENSEMBL proteins: 
 ENSP00000361721  

CITED4 Human Recombinant Protein Products:

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CITED4 Antibody Products:

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LSBio Antibodies in human, mouse, rat for CITED4

CITED4 Assay Products:

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Cloud-Clone Corp. ELISAs for CITED4
Cloud-Clone Corp. CLIAs for CITED4


(According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
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1 InterPro protein domain:
 IPR007576 CITED

Graphical View of Domain Structure for InterPro Entry Q96RK1

ProtoNet protein and cluster: Q96RK1

UniProtKB/Swiss-Prot: CITE4_HUMAN, Q96RK1
Similarity: Belongs to the CITED family


CITED4 for domains           About GeneDecksing


(According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Molecular Function:

     UniProtKB/Swiss-Prot Summary: CITE4_HUMAN, Q96RK1
Function: Acts as transcriptional coactivator for TFAP2/AP-2. Enhances estrogen-dependent transactivation mediated
by estrogen receptors. May function as an inhibitor of transactivation by HIF1A by disrupting HIF1A interaction
with CREBBP. May be involved in regulation of gene expression during development and differentiation of blood
cells, endothelial cells and mammary epithelial cells

     Gene Ontology (GO): 1 molecular function term:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0003713transcription coactivator activity ISS--
     
CITED4 for ontologies           About GeneDecksing


Phenotypes:
     1 MGI mutant phenotype (inferred from 1 allele(MGI details for Cited4):
 no phenotypic analysis 

CITED4 for phenotypes           About GeneDecksing

Animal Models:
   inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for CITED4
   inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for CITED4

   genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for CITED4
   genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for CITED4

miRNA
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Selected qRT-PCR Assays for microRNAs that regulate CITED4 (see all 13):
hsa-miR-3130-5p hsa-miR-20a hsa-miR-519d hsa-miR-4328 hsa-miR-106a hsa-miR-106b hsa-miR-659 hsa-miR-93
SwitchGear 3'UTR luciferase reporter plasmidCITED4 3' UTR sequence
Inhib. RNA
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OriGene RNAi products in human, mouse, rat for CITED4
Predesigned siRNA for gene silencing in human, mouse, rat CITED4

Gene Editing
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Clone
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OriGene ORF clones in mouse, rat for CITED4
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector: CITED4 (NM_133467)
Browse Sino Biological Human cDNA Clones
DNA2.0 Custom Codon Optimized Gene Synthesis Service for CITED4
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CITED4

Cell Line
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In Situ Assay
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Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CITED4


(According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
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Subcellular locations from UniProtKB/Swiss-Prot
CITE4_HUMAN, Q96RK1: Nucleus. Cytoplasm
Subcellular locations from COMPARTMENTS: 

CompartmentConfidence
nucleus5
cytosol2
extracellular1

Gene Ontology (GO): 2 cellular component terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0005634nucleus IEA--
GO:0005737cytoplasm IEA--

CITED4 for ontologies           About GeneDecksing


(SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
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    Custom Pathway & Disease-focused RT2 Profiler PCR Arrays for CITED4
Interactions:

    GeneGlobe Interaction Network for CITED4

STRING Interaction Network Preview (showing 5 interactants - click image to see more details)

Selected Interacting proteins for CITED4 (Q96RK13 ENSP000003617214) via UniProtKB, MINT, STRING, and/or I2D (see all 19)
InteractantInteraction Details
GeneCardExternal ID(s)
TFAP2CQ927543, ENSP000002010314I2D: score=2 STRING: ENSP00000201031
IVNS1ABPQ9Y6Y03, ENSP000003564684I2D: score=1 STRING: ENSP00000356468
EP300Q094723, ENSP000002632534I2D: score=2 STRING: ENSP00000263253
TFAP2AP055493, ENSP000003689244I2D: score=2 STRING: ENSP00000368924
TFAP2BQ924813, ENSP000003772654I2D: score=2 STRING: ENSP00000377265
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Gene Ontology (GO): 4 biological process terms:    About this table

GO IDQualified GO termEvidencePubMed IDs
GO:0006351transcription, DNA-templated IEA--
GO:0006355regulation of transcription, DNA-templated ----
GO:0043627response to estrogen ISS--
GO:0045893positive regulation of transcription, DNA-templated IEA--

CITED4 for ontologies           About GeneDecksing



(Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
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Browse Small Molecules at EMD Millipore
   Browse drugs & compounds from Enzo Life Sciences
  Browse compounds at ApexBio 

Browse Tocris compounds for CITED4 (CITE4)



(Secondary structures according to fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
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REFSEQ mRNAs for CITED4 gene: 
NM_133467.2  

Unigene Cluster for CITED4:

Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 4
Hs.355820  [show with all ESTs]
Unigene Representative Sequence: BM909126
1 Ensembl transcript including schematic representation, and UCSC links where relevant:
ENST00000372638(uc001cgj.3)
miRNA
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Selected qRT-PCR Assays for microRNAs that regulate CITED4 (see all 13):
hsa-miR-3130-5p hsa-miR-20a hsa-miR-519d hsa-miR-4328 hsa-miR-106a hsa-miR-106b hsa-miR-659 hsa-miR-93
SwitchGear 3'UTR luciferase reporter plasmidCITED4 3' UTR sequence
Inhib. RNA
Products:
     
OriGene RNAi products in human, mouse, rat for CITED4
Predesigned siRNA for gene silencing in human, mouse, rat CITED4
Clone
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OriGene ORF clones in mouse, rat for CITED4
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
GenScript: all cDNA clones in your preferred vector: CITED4 (NM_133467)
DNA2.0 Custom Codon Optimized Gene Synthesis Service for CITED4
Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CITED4
Primer
Products:
    
OriGene qPCR primer pairs and template standards for CITED4
OriGene qSTAR qPCR primer pairs in human, mouse for CITED4
Pre-validated RT2 qPCR Primer Assay in human, mouse, rat CITED4
  QuantiTect SYBR Green Assays in human, mouse, rat CITED4
  QuantiFast Probe-based Assays in human, mouse, rat CITED4

Additional mRNA sequence: 

BC035496.2 BC052559.1 

1 DOTS entry:

DT.453789 

Selected AceView cDNA sequences (see all 53):

BE048502 NM_133467 BC052559 BC035496 BQ445917 AI271898 AI553937 AI452509 
AI244810 CB850978 CB240666 AW059537 BU634356 C00201 BI966153 BQ025809 
BQ187395 BM760997 CK904042 BM843794 BV206373 BV175002 BQ024919 BV184432 

GeneLoc Exon Structure


(RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
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CITED4 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS <intensity>2/3
CGAP TAG: GACGCCGAAC
CITED4 Expression
About this image


CITED4 expression in embryonic tissues and stem cells    About this table
Data from LifeMap, the Embryonic Development and Stem Cells Database
 selected tissues (see all 10) fully expand
 
 Ovary (Reproductive System)    fully expand to see all 3 entries
         Granulosa Cells Primary Follicle
         Secondary follicles
 
 Epithelial Cells
         Fetal Matrix Cells Hair Follicle
 
 Bone (Muscoskeletal System)
         Prechondrocytic Mesenchymal Cells Zeugopod
 
 Cartilage (Muscoskeletal System)
         Prechondrocytic Mesenchymal Cells Zeugopod
 
 Heart (Cardiovascular System)
         Cardiac Crescent Cells Cardiac Crescent
CITED4 Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

CITED4 Protein Expression

SOURCE GeneReport for Unigene cluster: Hs.355820

UniProtKB/Swiss-Prot: CITE4_HUMAN, Q96RK1
Tissue specificity: Expressed in most tissues examined with highest levels of expression in heart, liver, skeletal
muscle and pancreas. Also expressed in bladder cell line ECV-304 and in various breast cancer cell lines. Also
detected in both in situ and invasive breast tumors where its expression is down-regulated and mostly restricted
to the cytoplasm of malignant epithelium. Down-regulation of expression is associated with elevated levels of
HIF1A and increased tumor growth and angiogenesis

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QuantiFast Probe-based Assays in human, mouse, rat CITED4
In Situ
Assay Products:
 

 
Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CITED4

(Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
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This gene was present in the common ancestor of chordates.

Orthologs for CITED4 gene from Selected species (see all 8)    About this table
Organism Taxonomic
classification
Gene Description Human
Similarity
Orthology
Type
Details
mouse
(Mus musculus)
Mammalia Cited41 , 5 Cbp/p300-interacting transactivator, with Glu/Asp-rich more1, 5 79.14(n)1
74.86(a)1
  4 (56.52 cM)5
562221  NM_019563.21  NP_062509.11 
 1206665725 
chicken
(Gallus gallus)
Aves CITED36
Gallus gallus Cbp/p300-interacting transactivator,...
32(a)
1 ↔ 1
23(1392832-1394720)
zebrafish
(Danio rerio)
Actinopterygii cited4b6
cited4a6
Cbp/p300-interacting transactivator, with Glu/Asp-...
Cbp/p300-interacting transactivator, with Glu/Asp-...
25(a)
25(a)
1 ↔ many
1 ↔ many
16(39508173-39510493) ENSDARG00000028514
19(15283260-15287461) ENSDARG00000035990


ENSEMBL Gene Tree for CITED4 (if available)
TreeFam Gene Tree for CITED4 (if available)

(Paralogs according to 1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
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Paralogs for CITED4 gene
CITED12  CITED22  

CITED4 for paralogs           About GeneDecksing



(SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
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Selected SNPs for CITED4 (see all 96)    About this table    
Genomic DataTranscription Related DataAllele Frequencies
SNP IDValidClinical
significance
Chr 1 posSequence#AA
Chg
TypeMore#Allele
freq
PopTotal
sample
More
----------
rs729491451,2
C--41326269(+) TTGCCG/TTCACT 1 -- int14Minor allele frequency- T:0.22WA NA EA 360
rs120892331,2
C--41326351(+) TCCCTC/TTGGGA 1 -- int12Minor allele frequency- T:0.00NA 4
rs1809015611,2
--41326352(+) CCCTCC/TGGGAA 1 -- int10--------
rs759113011,2
C--41326361(+) AAACCG/ACCTCA 1 -- int14Minor allele frequency- A:0.24WA NA EA 360
rs1863126651,2
--41326407(+) GAGTCA/CGGGTC 1 -- int10--------
rs729491461,2
C--41326433(+) TGAACT/CCGGTG 1 -- int14Minor allele frequency- C:0.23WA NA EA 360
rs1923675451,2
--41326464(+) AGAGCA/TCCAAG 1 -- int10--------
rs729491471,2
C,F--41326480(+) CCCACC/GCTACC 1 -- int14Minor allele frequency- G:0.07WA CSA NA 241
rs1509092881,2
--41326506(+) CCCAGC/TGGGTT 1 -- int10--------
rs121404411,2
C--41326597(+) ACTGTC/TGGTTT 1 -- int13Minor allele frequency- T:0.10NA WA 240

HapMap Linkage Disequilibrium report for CITED4 (41326728 - 41328018 bp)

Structural Variations
      Database of Genomic Variants (DGV) variations for CITED4: --
Site Specific Mutation Identification with PCR Assays
SeqTarget long-range PCR primers for resequencing CITED4
DNA2.0 Custom Variant and Variant Library Synthesis for CITED4

(in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
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OMIM gene information: 606815    OMIM disorders: --

3 diseases for CITED4:    
About MalaCards
hypoxia    endotheliitis    breast cancer


CITED4 for disorders           About GeneDecksing

Genetic Association Database (GAD): CITED4
Human Genome Epidemiology (HuGE) Navigator: CITED4 (1 document)

Export disorders for CITED4 gene to outside databases

(in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
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PubMed articles for CITED4 gene integrated from 10 sources:
(articles sorted by number of sources associating them with CITED4)
    Utopia: connect your pdf to the dynamic
world of online information

  1. Human CREB-binding protein/p300-interacting transactivator with ED- rich tail (CITED) 4, a new member of the CITED family, functions as a co-activator for transcription factor AP-2. (PubMed id 11744733)1, 2, 3 Braganca J.... Bhattacharya S. (J. Biol. Chem. 2002)
  2. A large-scale candidate gene association study of age at menarche and age at natural menopause. (PubMed id 20734064)1, 4 He C....Hunter D.J. (Hum. Genet. 2010)
  3. CITED4 inhibits hypoxia-activated transcription in cancer cells, and its cytoplasmic location in breast cancer is associated with elevated expression of tumor cell hypoxia-inducible factor 1alpha. (PubMed id 15342390)1, 2 Fox S.B.... Harris A.L. (Cancer Res. 2004)
  4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
  5. Aberrant DNA methylation but not mutation of CITED4 is associated with alteration of HIF-regulated genes in breast cancer. (PubMed id 21755341)1 Huang K.T....Fox S.B. (Breast Cancer Res. Treat. 2011)
  6. Mutational analysis of the CITED4 gene in glioblastomas. (PubMed id 18722883)1 Torres-MartA-n M....Rey J.A. (Cancer Genet. Cytogenet. 2008)
  7. Hypermethylation and transcriptional downregulation of the CITED4 gene at 1p34.2 in oligodendroglial tumours with allelic losses on 1p and 19q. (PubMed id 17311001)1 Tews B....Lichter P. (Oncogene 2007)
  8. Interaction and functional cooperation between the LIM protein FHL2, CBP/p300, and beta-catenin. (PubMed id 15572674)1 Labalette C....Wei Y. (Mol. Cell. Biol. 2004)
  9. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PubMed id 12477932)1 Strausberg R.L....Marra M.A. (Proc. Natl. Acad. Sci. U.S.A. 2002)
  10. (PubMed id )2 

(in PubMed, OMIM, and NCBI Bookshelf)
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 ANDOR
Aliases
Free Text  

  Query String
PubMed
OMIM
NCBI Bookshelf
  (Note: In FireFox, select the above section and copy using Ctrl-C)

(According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
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Entrez Gene: 163732 HGNC: 18696 AceView: CITED4 Ensembl:ENSG00000179862 euGenes: HUgn163732
ECgene: CITED4 H-InvDB: CITED4

(According to HUGE)
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  --

(According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
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NameDescription
PharmGKB entry for CITED4 Pharmacogenomics, SNPs, Pathways
ATLAS Chromosomes in Cancer entry for CITED4 Genetics and Cytogenetics in Oncology and Haematology

(Patent information from GeneIP,
Licensable technologies from WIS Yeda, Salk, Tufts,
IP news from LifeMap Sciences, Inc.)
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Patent Information for CITED4 gene:
Search GeneIP for patents involving CITED4

GeneCards and IP:
Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
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