CISD2 Gene
protein-coding GIFtS: 47
GCID: GC04P103790
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|
CDGSH iron sulfur domain 2(Previous names: zinc finger, CDGSH-type domain 2, Wolfram syndrome 2 )
(Previous symbols: ZCD2, WFS2)
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Aliases
for CISD2 gene
(According to
1HGNC,
2Entrez Gene,
3UniProtKB/Swiss-Prot,
4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc,
7Ensembl,
8DME,
9miRBase,
and/or 10fRNAdb)
About This Section
|
| Aliases |
|---|
| CDGSH Iron Sulfur Domain 21 2 | | MitoNEET-Related 1 Protein2 3 | | ERIS1 2 3 5 | | Nutrient-Deprivation Autophagy Factor-12 3 | | ZCD21 2 3 5 | | NAF-12 3 | | Miner11 2 3 | | Wolfram Syndrome 21 | | WFS21 2 5 | | CDGSH Iron-Sulfur Domain-Containing Protein 22 | | Zinc Finger, CDGSH-Type Domain 21 2 | | MitoNEET Related 12 | | Endoplasmic Reticulum Intermembrane Small Protein2 3 | | CDGSH23 |
Export aliases for CISD2 gene to outside databasesPrevious GC identifers: GC04P104010 GC04P099526 |
Summaries
for CISD2 gene(According to Entrez Gene,
Tocris Bioscience,
Wikipedia's
Gene Wiki,
PharmGKB,
UniProtKB/Swiss-Prot,
and/or
UniProtKB/TrEMBL)
About This Section
|
Entrez Gene summary for CISD2:
The protein encoded by this gene is a zinc finger protein that localizes to the endoplasmic reticulum. The encodedprotein binds an iron/sulfur cluster and may be involved in calcium homeostasis. Defects in this gene are a cause ofWolfram syndrome 2. (provided by RefSeq, Mar 2011)
UniProtKB/Swiss-Prot: CISD2_HUMAN, Q8N5K1Function: Regulator of autophagy that contributes to antagonize BECN1-mediated cellular autophagy at the endoplasmicreticulum. Participates in the interaction of BCL2 with BECN1 and is required for BCL2-mediated depression ofendoplasmic reticulum Ca(2+) stores during autophagy. Contributes to BIK-initiated autophagy, while it is not involvedin BIK-dependent activation of caspases. Involved in life span control, probably via its function as regulator ofautophagy
|
Genomic Views
for CISD2 gene
(According to
GeneLoc and/or
HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to
UCSC (hg19) and
Ensembl (release 69),
Regulatory elements and Epigenetics data according to
QIAGEN,
SABiosciences, and/or
SwitchGear Genomics)
About This Section
| RefSeq DNA sequence:- NC_000004.11 NC_018915.1 NT_016354.19
Regulatory elements:
 SABiosciences Regulatory transcription factor binding sites in the CISD2 gene promoter:
USF1 NF-E2 p45 CREB E2F-1 E2F HSF2 USF-1 deltaCREB MRF-2 NF-E2
Other transcription factors
Search SABiosciences Chromatin IP Primers for CISD2
Epigenetics:
| | QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CISD2 |
Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track
Entrez Gene cytogenetic band: 4q24 Ensembl cytogenetic band: 4q24 HGNC cytogenetic band: 4q24CISD2 Gene in genomic location: bands according to Ensembl, locations according to
 (and/or Entrez Gene and/or Ensembl if different)
GeneLoc information about chromosome 4 GeneLoc Exon Structure GeneLoc location for GC04P103790: view genomic region
(about GC identifiers)
Start:
|
103,790,135 bp from pter |
End:
|
103,813,964 bp from pter |
Size:
|
23,830 bases |
Orientation:
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plus strand |
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Proteins
for CISD2 gene
(According to
1UniProtKB,
HORDE,
neXtProt,
Ensembl,
and/or Reactome,
Modification sites according to 2PhosphoSitePlus,
Specific Peptides from DME,
Protein expression images according to data from SPIRE MOPED and PaxDb,
RefSeq according to NCBI,
PDB rendering according to OCA and/or Proteopedia,
Recombinant Proteins
from
EMD Millipore,
R&D Systems,
GenScript,
Enzo Life Sciences,
OriGene,
Novus Biologicals,
Sino Biological,
ProSpec, and/or
Uscn,
Biochemical Assays by
EMD Millipore,
R&D Systems,
OriGene,
GenScript,
Cell Signaling Technology,
Enzo Life Sciences, and/or
Uscn,
Ontologies according to Gene
Ontology Consortium 01 Mar 2013 and
Entrez Gene,
Antibodies by
EMD Millipore,
R&D Systems,
GenScript,
Cell Signaling Technology,
OriGene,
Novus Biologicals,
Thermo Fisher Scientific,
Abcam, and/or
Uscn)
About This Section
|
UniProtKB/Swiss-Prot: CISD2_HUMAN, Q8N5K1 (See
protein sequence)Recommended Name: CDGSH iron-sulfur domain-containing protein 2 Size: 135 amino acids; 15278 Da
Cofactor: Binds 1 2Fe-2S cluster
Subunit: Homodimer. Interacts with BCL2; the interaction is direct and disrupted by BIK interaction with BCL2.Interacts with BCL2L1. Interacts with ITPR1
Subcellular location: Endoplasmic reticulum membrane; Single-pass membrane protein. Mitochondrion outer membrane;Single-pass membrane protein. Note=According to PubMed:20010695, it mainly localizes to the endoplasmic reticulum.However, experiments in mouse showed that it mainly localizes to the mitochondrion outer membrane
Caution: Although initially thought (PubMed:17846994) to be a zinc-finger protein, it was later shown (PubMed:17376863)that it binds 1 2Fe-2S cluster instead
Sequence caution: Sequence=CAD97935.1; Type=Erroneous initiation;
1 PDB 3D structure from  and Proteopedia  for CISD2:3FNV (3D)
Secondary accessions: Q7Z3D5Explore the universe of human proteins at neXtProt for CISD2: NX_Q8N5K1
Post-translational modifications:
View modification sites using PhosphoSitePlus2View neXtProt modification sites for NX_Q8N5K1
CISD2 Protein expression data from MOPED and PaxDb: About this image 
REFSEQ proteins: NP_001008389.1
ENSEMBL proteins: ENSP00000273986 ENSP00000458976 ENSP00000423716
Human Recombinant Protein Products for CISD2:
Gene Ontology (GO): 5/6 cellular component terms (GO ID links to tree view) (see all 6): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0005741 | mitochondrial outer membrane |
ISS | -- | | GO:0005783 | endoplasmic reticulum |
IDA | -- | | GO:0005789 | endoplasmic reticulum membrane |
IDA | -- | | GO:0016021 | integral to membrane |
IEA | -- | | GO:0043231 | intracellular membrane-bounded organelle |
-- | -- |
CISD2 for ontologies About GeneDecksing
CISD2 Antibody Products:
Assay Products for CISD2: |
Protein
Domains /
Families
for CISD2 gene(According to InterPro, ProtoNet,
UniProtKB, and/or BLOCKS,
Sets of similar genes according to GeneDecks)
About This Section
|
CISD2 for domains About GeneDecksing
3 InterPro domains/families:Graphical View of Domain Structure for InterPro Entry Q8N5K1ProtoNet protein and cluster: Q8N5K1 UniProtKB/Swiss-Prot: CISD2_HUMAN, Q8N5K1Similarity: Belongs to the CISD protein family. CISD2 subfamily |
Function
for CISD2 gene
(According to 1UniProtKB,
Genatlas,
LifeMap Discovery™,
IUBMB, and/or
2DME,
Human phenotypes from GenomeRNAi,
Animal models from MGI Mar 06 2013,
inGenious Targeting Laboratory,
bound targets from SABiosciences,
miRNA Gene Targets from miRTarBase,
shRNA from
OriGene,
Sirion Biotech,
RNAi from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
microRNA from QIAGEN,
Gene Editing from DNA2.0,
Sirion Biotech,
Clones from EMD Millipore,
OriGene,
SwitchGear Genomics,
GenScript,
Sino Biological,
DNA2.0,
and Vector BioLabs,
Cell Lines from GenScript,
LifeMap BioReagents,
Sirion Biotech,
In Situ Hybridization Assays from Advanced Cell Diagnostics,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene.)
About This Section
|
Molecular Function:
UniProtKB/Swiss-Prot Summary: CISD2_HUMAN, Q8N5K1Function: Regulator of autophagy that contributes to antagonize BECN1-mediated cellular autophagy at the endoplasmicreticulum. Participates in the interaction of BCL2 with BECN1 and is required for BCL2-mediated depression ofendoplasmic reticulum Ca(2+) stores during autophagy. Contributes to BIK-initiated autophagy, while it is not involvedin BIK-dependent activation of caspases. Involved in life span control, probably via its function as regulator ofautophagyBiophysicochemical properties: Redox potential: E is 0 +/- 10 mV for 2Fe-2S at pH 7.5; Gene Ontology (GO): 4 molecular function terms (GO ID links to tree view): About this table
CISD2 for ontologies About GeneDecksing
Phenotypes:
15/20 MGI mutant phenotypes (inferred from 3 alleles ) (MGI details for Cisd2) (see all 20):
CISD2 for phenotypes About GeneDecksing
Animal Models:
Mouse knock-out Cisd2tm1Tfts for CISD2
Clone
Products: |  | Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore | |  | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CISD2 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CISD2 (see all 2)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
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In Situ Assay
Products: |
 | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CISD2 |
|
Pathways & Interactions
for CISD2 gene
(Pathways according to
EMD Millipore,
R&D Systems,
Cell Signaling Technology,
KEGG,
PharmGKB,
BioSystems,
Reactome,
Tocris Bioscience,
GeneGo (Thomson Reuters),
QIAGEN,
and/or UniProtKB,
Sets of similar genes according to GeneDecks,
Interaction Networks according to
SABiosciences,
and/or STRING,
Interactions according to 1UniProtKB,
2MINT,
3I2D, and/or
4STRING,
with links to IntAct and
Ensembl,
Ontologies according to Gene Ontology Consortium 01 Mar 2013 via
Entrez Gene).
About This Section
|
Interactions:
Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CISD2
STRING Interaction
Network Preview (showing 5 interactants - click image to see 6)
5/7 Interacting proteins for CISD2 (Q8N5K13 ENSP000002739864) via UniProtKB, MINT, STRING, and/or I2D (see all 7)About this table
Gene Ontology (GO): 3 biological process terms (GO ID links to tree view): About this table | GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|
| GO:0000422 | mitochondrion degradation |
IEA | -- | | GO:0010259 | multicellular organismal aging |
ISS | -- | | GO:0010506 | regulation of autophagy |
IMP | -- |
CISD2 for ontologies About GeneDecksing
|
Drugs & Compounds
for CISD2 gene(Chemical Compounds according to UniProtKB, Enzo Life Sciences,
EMD Millipore, Tocris Bioscience
HMDB,
BitterDB, and/or
Novoseek, and Drugs according to
DrugBank,
Enzo Life Sciences, and/or
PharmGKB, with drugs/clinical trials/news
search links to CenterWatch)
About This Section
|
 Browse Tocris compounds for CISD2
2 HMDB Compounds for CISD2 About this table
Search CenterWatch for drugs/clinical trials and news about CISD2
|
Transcripts
for CISD2 gene(Secondary structures according to
fRNAdb,
GenBank/EMBL/DDBJ Accessions according to
Unigene
(Build 235 Homo sapiens; Mar 10 2013) or GenBank,
RefSeq according to Entrez Gene,
DOTS (version 10), and/or
AceView,
transcript ids from Ensembl
with links to UCSC,
exon structure from GeneLoc,
alternative splicing isoforms according to ASD and/or
ECgene,
RNAi Products from
EMD Millipore,
siRNAs from
OriGene,
QIAGEN,
shRNA from
OriGene,
Sirion Biotech,
microRNA from QIAGEN,
Tagged/untagged cDNA clones from
OriGene,
SwitchGear Genomics,
GenScript,
DNA2.0,
Vector BioLabs,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN
)
About This Section
|
REFSEQ mRNAs for CISD2 gene: NM_001008388.4 Unigene Cluster for CISD2: CDGSH iron sulfur domain 2 Hs.444955 [show with all ESTs]Unigene Representative Sequence: NM_0010083883 Ensembl transcripts including schematic representations, and UCSC links where relevant: ENST00000273986(uc003hwt.4) ENST00000574446 ENST00000503643
Clone
Products: | | OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CISD2 (see all 2)
OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CISD2 (see all 2)
OriGene custom cloning services - gene synthesis, subcloning, mutagenesis,
variant library, vector shuttling
| | | GenScript: all cDNA clones in your preferred vector: CISD2 (NM_001008388) | | | DNA2.0 Custom Codon Optimized Gene
Synthesis Service for CISD2 | | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CISD2 |
Additional cDNA sequence: AK292134.1 BC020831.1 BC032300.1 BX537971.1 13 DOTS entries: DT.100799362 DT.100798687 DT.215563 DT.100798688 DT.100798685 DT.100798682 DT.40127037 DT.100798684 DT.97779343 DT.121253305 DT.97775151 DT.100798686 DT.95136342
GeneLoc Exon Structure
|
Expression
for CISD2 gene
(RNA expression data according to
H-InvDB,
NONCODE,
miRBase, and
RNAdb,
Expression images according to data from
BioGPS,
Illumina Human BodyMap, and
CGAP
SAGE,
Sets of similar genes according to GeneDecks,
in vivo and in vitro expression data from LifeMap Discovery™,
plus additional links to
Genevestigator, and/or
SOURCE, and/or
BioGPS, and/or
UniProtKB,
PCR Arrays from
SABiosciences,
Primers from
OriGene,
SABiosciences, and/or
QIAGEN,
In Situ Hybridization Assays from Advanced Cell Diagnostics)
About This Section
| CISD2 expression in normal human tissues (normalized intensities)
See probesets specificity/sensitivity at GeneAnnot
About this imageBioGPS
CGAP TAG: CACAAATGCT
About this image
See CISD2 Protein Expression from SPIRE MOPED and PaxDB
Genevestigator expression for CISD2
SOURCE GeneReport for Unigene cluster: Hs.444955
UniProtKB/Swiss-Prot: CISD2_HUMAN, Q8N5K1Tissue specificity: Testis, small intestine, kidney, lung, brain, heart, pancreas and platelets
SABiosciences Custom PCR Arrays for CISD2
Primer
Products: | | OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CISD2
Browse OriGene validated miRNA SYBR primer pairs
| | | SABiosciences RT2 qPCR Primer Assay in human, mouse, rat CISD2 | | | QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CISD2 | | | QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CISD2 | In Situ
Assay Products: |
| Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CISD2 |
Orthologs
for CISD2 gene
(Orthologs according to
1,2HomoloGene (2older version, for species not in 1newer version),
3euGenes,
4SGD
,
5MGI Mar 06 2013,
with possible further links to
Flybase
and/or
WormBase,
and/or
6Ensembl pan taxonomic compara ,
Gene Trees according to Ensembl and
TreeFam)
About This Section
|
This gene was present in the common ancestor of eukaryotes.
Orthologs for CISD2 gene from 5/18 species (see all 18) About this table
| Organism |
Taxonomic
classification |
Gene |
Description |
Human
Similarity |
Orthology
Type |
Details |
chicken
(Gallus gallus) |
Aves |
CISD21 |
CDGSH iron sulfur domain 2 |
83.83(n)
95.52(a) |
|
422714 XM_420668.3 XP_420668.1 |
zebrafish
(Danio rerio) |
Actinopterygii |
cisd21 |
CDGSH iron sulfur domain 2 |
68.17(n)
81.2(a) |
|
393354 NM_200383.1 NP_956677.1 |
fruit fly
(Drosophila melanogaster) |
Insecta |
CG14581 |
CG1458 |
49.87(n)
47.29(a) |
|
43459 NM_143427.3 NP_651684.1 |
thale cress
(Arabidopsis thaliana) |
eudicotyledons |
AT5G517206 |
Iron-binding zinc finger CDGSH type domain-contain... |
37(a) |
1 → many |
5(21009592-21010345) |
rice
(Oryza sativa) |
Liliopsida |
-- |
CDGSH iron sulfur domain-containing protein 1, put... |
39(a) |
1 → many |
7(16598918-16601043) |
ENSEMBL Gene Tree for CISD2 (if available)
TreeFam Gene Tree for CISD2 (if available) |
Paralogs
for CISD2 gene(Paralogs according to
1HomoloGene,
2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
About This Section
| Paralogs for CISD2 gene
- CISD12
1 SIMAP similar gene for CISD2 using alignment to 3 protein entries: CISD2_HUMAN (see all proteins):CISD1
CISD2 for paralogs About GeneDecksing
4 Pseudogenes.org Pseudogenes for CISD2
PGOHUM00000238741 PGOHUM00000248824 PGOHUM00000246378 PGOHUM00000240772
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Genomic Variants
for CISD2 gene(SNPs/Variants according to the
1NCBI SNP Database,
2Ensembl,
3PupaSUITE,
UniProtKB, and
DNA2.0,
Linkage Disequilibrium by HapMap,
Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene
Mutation Database (HGMD) and the Locus Specific Mutation
Databases (LSDB), Blood group antigen gene mutations by BGMUT,
Resequencing Primers from QIAGEN,
Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
About This Section
|
| Genomic Data | Transcription Related Data | Allele Frequencies | | SNP ID | Valid | Clinical
significance | Chr 4 pos | Sequence | # | AA
Chg | Type | More | # | Allele
freq | Pop | Total
sample | More |
|---|
HapMap Linkage Disequilibrium report for CISD2 (103790135 - 103813964 bp)
Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
Database of Genomic Variants (DGV): 3 variations for CISD2
3 CNVs: 92278 3505 92279
Human Gene Mutation Database (HGMD): CISD2
Locus Specific Mutation Databases (LSDB): CISD2
| SABiosciences Cancer Mutation PCR Assays |
| | QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CISD2 |
|
Disorders
/ Diseases
for CISD2 gene
(in which this Gene is Involved, According to MalaCards,
OMIM, UniProtKB,
the University of Copenhagen DISEASES
database,
Genatlas, GeneTests,
GAD,
HuGE Navigator,
and/or TGDB.)
About This Section
|
CISD2 for disorders About GeneDecksing
OMIM gene information: 611507
OMIM disorders: 604928
UniProtKB/Swiss-Prot: CISD2_HUMAN, Q8N5K1
Defects in CISD2 are the cause of Wolfram syndrome type 2 (WFS2) [MIM:604928]. A rare disorder characterizedby juvenile-onset insulin-dependent diabetes mellitus with optic atrophy. Other manifestations include diabetesinsipidus, sensorineural deafness, dementia, psychiatric illnesses. WFS2 patients additionally show a strong bleedingtendency and gastrointestinal ulceration. Diabetes insipidus may be absent
5  diseases for CISD2: About MalaCardswolfram syndrome 2 wolfram syndrome diabetes insipidus optic atrophy
dementia
3 diseases from the University of Copenhagen DISEASES database for CISD2:Wolfram syndrome Optic atrophy Diabetes insipidus Export disorders for CISD2 gene to outside databases
|
Publications
for CISD2 gene (in
PubMed.
Associations of this gene to articles via
1Entrez Gene,
2UniProtKB/Swiss-Prot,
3HGNC,
4GAD,
5PharmGKB,
6HMDB,
7DrugBank,
8UniProtKB/TrEMBL,
9 Novoseek, and/or
10fRNAdb)
About This Section
|
PubMed articles for CISD2 gene, integrated from 9 sources (see all 26):
(articles sorted by number of sources associating them with CISD2) | |  | Utopia: connect your pdf to the dynamic
world of online information |
- A homozygous mutation in a novel zinc-finger protein, ERIS, is responsible for Wolfram syndrome 2. (PubMed id 17846994)1, 2, 3 Amr S....Shiang R. (2007)
- MitoNEET is an iron-containing outer mitochondrial membrane protein that regulates oxidative capacity. (PubMed id 17376863)1, 2, 3 Wiley S.E.... Dixon J.E. (2007)
- Antagonism of Beclin 1-dependent autophagy by BCL-2 at the endoplasmic reticulum requires NAF-1. (PubMed id 20010695)1, 2 Chang N.C.... Shore G.C. (2010)
- Crystal structure of Miner1: The redox-active 2Fe-2S protein causative in Wolfram Syndrome 2. (PubMed id 19580816)1, 2 Conlan A.R.... Paddock M.L. (2009)
- The outer mitochondrial membrane protein mitoNEET contains a novel redox-active 2Fe-2S cluster. (PubMed id 17584744)1, 3 Wiley S.E....Dixon J.E. (2007)
- A yeast two-hybrid screen reveals that osteopontin ass ociates with MAP1A and MAP1B in addition to other proteins linked to microtubule stability, apoptosis and protein degradation in the human brain. (PubMed id 22779921)1 Long P....Rose S. (2012)
- Initial characterization of the human central proteome. (PubMed id 21269460)2 Burkard T.R.... Colinge J. (2011)
- A proteome-wide, quantitative survey of in vivo ubiqui tylation sites reveals widespread regulatory roles. (PubMed id 21890473)1 Wagner S.A....Choudhary C. (2011)
- Interactions of pathological hallmark proteins: tubul in polymerization promoting protein/p25, beta-amyloid, and alpha-synuclein. (PubMed id 21832049)1 OlA!h J....OvA!di J. (2011)
- Mass spectrometric analysis of lysine ubiquitylation r eveals promiscuity at site level. (PubMed id 21139048)1 Danielsen J.M....Nielsen M.L. (2011)
|
External Searches for CISD2 gene
(in PubMed,
OMIM, and NCBI Bookshelf)
About This Section
|
|
Genome Databases showing CISD2 gene
(According to
Entrez Gene,
HGNC,
AceView,
euGenes,
Ensembl,
miRBase,
ECgene,
Kegg,
and/or
H-InvDB)
About This Section
|
|
Other Databases showing CISD2 gene
(According to HUGE)
About This Section
| -- |
Specialized Databases showing CISD2 gene(According to PharmGKB,
ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
About This Section
|
| Name | Description |
| PharmGKB entry for CISD2 | Pharmacogenomics, SNPs, Pathways |
|
| | |
About This Section
| Patent Information for CISD2 gene:
Search GeneIP for patents involving CISD2
GeneCards and IP:
Japan Patent Office Licenses GeneCards European Patent Office Licenses GeneCards Improving the IP Search
|
Products
for CISD2 gene(Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0 and Sirion Biotech, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, LifeMap BioReagents, and Sirion Biotech, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or
Enzo Life Sciences, In Situ Hybridization Assays from
Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory)
About This Section
|
 | |
 | |
 |
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 | | | CISD2 Proteins, Antibodies, CLIAs, and ELISAs |
| | | | | Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CISD2 |
|  |  |  |  | | | | Search ThermoFisher Antibodies for CISD2 |
| | | Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CISD2 |
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