Aliases for CISD1 Gene
External Ids for CISD1 Gene
Previous HGNC Symbols for CISD1 Gene
Previous GeneCards Identifiers for CISD1 Gene
This gene encodes a protein with a CDGSH iron-sulfur domain and has been shown to bind a redox-active [2Fe-2S] cluster. The encoded protein has been localized to the outer membrane of mitochondria and is thought to play a role in regulation of oxidation. Genes encoding similar proteins are located on chromosomes 4 and 17, and a pseudogene of this gene is located on chromosome 2. [provided by RefSeq, Feb 2012]
GeneCards Summary for CISD1 Gene
CISD1 (CDGSH Iron Sulfur Domain 1) is a Protein Coding gene. Among its related pathways are Glucose / Energy Metabolism and Adipogenesis. GO annotations related to this gene include 2 iron, 2 sulfur cluster binding. An important paralog of this gene is CISD2.
UniProtKB/Swiss-Prot for CISD1 Gene
Plays a key role in regulating maximal capacity for electron transport and oxidative phosphorylation (By similarity). May be involved in Fe-S cluster shuttling and/or in redox reactions.