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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

CIDEC Gene

protein-coding   GIFtS: 51
GCID: GC03M009908

cell death-inducing DFFA-like effector c

 Explore 6 diseases affiliated with
CIDEC via our new
 Human Malady Compendium 
Biological research products
for CIDEC
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Cell Death-Inducing DFFA-Like Effector C1 2     Cell Death Activator CIDE-32
FSP272 3 5     Fat Specific Protein 272
CIDE-31 2     Cell Death-Inducing DFFA-Like Effector Protein C3
FLJ208711     Fat-Specific Protein FSP27 Homolog3
Fsp271     CIDEX5
CIDE32     

External Ids:    HGNC: 242291   Entrez Gene: 639242   Ensembl: ENSG000001872887   OMIM: 6121205   UniProtKB: Q96AQ73   

Export aliases for CIDEC gene to outside databases

Previous GC identifers: GC03M009884 GC03M009844


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for CIDEC:
This gene encodes a member of the cell death-inducing DNA fragmentation factor-like effector family. Members of this
family play important roles in apoptosis. The encoded protein promotes lipid droplet formation in adipocytes and may
mediate adipocyte apoptosis. This gene is regulated by insulin and its expression is positively correlated with
insulin sensitivity. Mutations in this gene may contribute to insulin resistant diabetes. A pseudogene of this gene is
located on the short arm of chromosome 3. Alternatively spliced transcript variants that encode different isoforms
have been observed for this gene. (provided by RefSeq, Dec 2010)

UniProtKB/Swiss-Prot: CIDEC_HUMAN, Q96AQ7
Function: May act as a CEBPB coactivator in white adipose tissue to control the expression of a subset of CEBPB
downstream target genes, including SOCS1, SOCS3, TGFB1, TGFBR1, ID2 and XDH (By similarity). Binds to lipid droplets
and regulates their enlargement, thereby restricting lipolysis and favoring storage. At focal contact sites between
lipid droplets, promotes directional net neutral lipid transfer from the smaller to larger lipid droplets. The
transfer direction may be driven by the internal pressure difference between the contacting lipid droplet pair. When
overexpressed in preadipocytes, induces apoptosis or increases cell susceptibility to apoptosis induced by serum
deprivation or TGFB treatment. As mature adipocytes, that express high CIDEC levels, are quite resistant to apoptotic
stimuli, the physiological significance of its role in apoptosis is unclear




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000003.11  NC_018914.1  NT_022517.18  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the CIDEC gene promoter:
         AP-1   ATF-2   MyoD   c-Jun   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 5): CIDEC promoter sequence
   Search SABiosciences Chromatin IP Primers for CIDEC

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CIDEC


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3p25.3   Ensembl cytogenetic band:  3p25.3   HGNC cytogenetic band: 3p25

CIDEC Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CIDEC gene location

GeneLoc information about chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03M009908:  view genomic region     (about GC identifiers)

Start:
9,908,398 bp from pter      End:
9,921,938 bp from pter
Size:
13,541 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: CIDEC_HUMAN, Q96AQ7 (See protein sequence)
Recommended Name: Cell death activator CIDE-3  
Size: 238 amino acids; 26754 Da
Subunit: Interacts with CEBPB (By similarity). Interacts with CIDEA
Subcellular location: Nucleus (By similarity). Endoplasmic reticulum (By similarity). Lipid droplet. Note=Diffuses
quickly on lipid droplet surface, but becomes trapped and clustered at lipid droplet contact sites, thereby enabling
its rapid enrichment at lipid droplet contact sites
Secondary accessions: C9JMN7 Q67DW9 Q9GZY9
Alternative splicing: 4 isoforms:  Q96AQ7-1   Q96AQ7-2   Q96AQ7-3   Q96AQ7-4   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for CIDEC: NX_Q96AQ7

Post-translational modifications:

  • Ubiquitinated and targeted to proteasomal degradation, resulting in a short half-life. Protein stability depends on
  • triaclyglycerol synthesis, fatty acid availability and lipid droplet formation (By similarity)1
  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q96AQ7

  • CIDEC Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins (4 alternative transcripts): 
    NP_001186480.1  NP_001186481.1  NP_001186552.1  NP_071377.2  

    ENSEMBL proteins: 
     ENSP00000338642   ENSP00000392975   ENSP00000400649   ENSP00000408631   ENSP00000411356  
     ENSP00000373328  

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    Browse ProSpec Recombinant Proteins
    Uscn Proteins for CIDEC

    Gene Ontology (GO): 5/6 cellular component terms (GO ID links to tree view) (see all 6):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005634nucleus IDA--
    GO:0005737cytoplasm IDA--
    GO:0005783endoplasmic reticulum IEA--
    GO:0005811lipid particle IEA--
    GO:0005829cytosol IDA12429024


    CIDEC for ontologies           About GeneDecksing



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    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    CIDEC for domains           About GeneDecksing

    1 InterPro domain/family:
     IPR003508 CAD

    Graphical View of Domain Structure for InterPro Entry Q96AQ7

    ProtoNet protein and cluster: Q96AQ7

    1 Blocks protein family: IPB003508 Caspase-activated nuclease CIDE-N

    UniProtKB/Swiss-Prot: CIDEC_HUMAN, Q96AQ7
    Similarity: Contains 1 CIDE-N domain


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: CIDEC_HUMAN, Q96AQ7
    Function: May act as a CEBPB coactivator in white adipose tissue to control the expression of a subset of CEBPB
    downstream target genes, including SOCS1, SOCS3, TGFB1, TGFBR1, ID2 and XDH (By similarity). Binds to lipid droplets
    and regulates their enlargement, thereby restricting lipolysis and favoring storage. At focal contact sites between
    lipid droplets, promotes directional net neutral lipid transfer from the smaller to larger lipid droplets. The
    transfer direction may be driven by the internal pressure difference between the contacting lipid droplet pair. When
    overexpressed in preadipocytes, induces apoptosis or increases cell susceptibility to apoptosis induced by serum
    deprivation or TGFB treatment. As mature adipocytes, that express high CIDEC levels, are quite resistant to apoptotic
    stimuli, the physiological significance of its role in apoptosis is unclear

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    Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003674molecular_function ND--


    CIDEC for ontologies           About GeneDecksing


    1 GenomeRNAi human phenotype for CIDEC:
     Increased circadian rhythm amp 

    Animal Models:
         Mouse knock-outs for CIDEC: Cidectm1Maka Cidectm1Pli
         6 MGI mutant phenotypes (inferred from 2 alleles(MGI details for Cidec):
     adipose tissue  behavior/neurological  growth/size  homeostasis/metabolism  integument 
     liver/biliary system 

    CIDEC for phenotypes           About GeneDecksing


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CIDEC

    2 Interacting proteins for CIDEC (Q96AQ73) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CIDEAO605433I2D: score=1 
    KIAA1279Q96EK53I2D: score=1 
    About this table

    Gene Ontology (GO): 4 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006351transcription, DNA-dependent IEA--
    GO:0006355regulation of transcription, DNA-dependent IEA--
    GO:0006915apoptotic process IEA--
    GO:0006917induction of apoptosis IDA12429024


    CIDEC for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for CIDEC
    Search CenterWatch for drugs/clinical trials and news about CIDEC 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
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    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for CIDEC gene (4 alternative transcripts): 
    NM_001199551.1  NM_001199552.1  NM_001199623.1  NM_022094.3  

    Unigene Cluster for CIDEC:

    Cell death-inducing DFFA-like effector c
    Hs.567562  [show with all ESTs]
    Unigene Representative Sequence: AF303893
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000336832(uc010hcp.3 uc003btp.3 uc003btq.3 uc021wsv.1 uc021wsw.1)
    ENST00000455015(uc003btr.3) ENST00000423850(uc003bto.3 uc003bts.3)
    ENST00000430427 ENST00000443115 ENST00000487454 ENST00000383817

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    hsa-miR-491-5p hsa-miR-486-3p
    SwitchGear 3'UTR luciferase reporter plasmidCIDEC 3' UTR sequence
    Inhib. RNA
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    Additional cDNA sequence: 

    AF303893.1 AK024524.1 AK024530.1 AY364638.1 AY364640.1 BC016851.1 

    5 DOTS entries:

    DT.95162686  DT.75104170  DT.100788704  DT.86845992  DT.100788703 

    24/43 AceView cDNA sequences (see all 43):

    AY364640 CD518776 BG740660 CD244693 AL598731 BQ694634 CD558840 AF303893 
    NM_022094 AY364638 AL598630 CB269236 CD517657 CD517940 CD518729 BQ695178 
    BG696770 CD519587 CB268955 AA321120 AK024530 AI460316 BM991792 BV193767 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for CIDEC    About this scheme

    ExUns: 1 ^ 2a · 2b ^ 3 ^ 4 ^ 5 ^ 6 ^ 7a · 7b · 7c · 7d · 7e
    SP1:                          -                                             
    SP2:                                                                        
    SP3:                    -     -                                             
    SP4:                          -                                             
    SP5:                          -     -     -                                 


    ECgene alternative splicing isoforms for CIDEC

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    CIDEC expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: TGATATTAGG

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image

    CIDEC expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    2 LifeMap In Vivo Development Anatomical Compartments/Cells 
    Tissue Anatomical Compartment CellCategory (developmental path)
    AdiposeBody Subcutaneous White AdiposeAdipose
    AdiposeVisceral White AdiposeAdipose
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization
    Stem Cell Differentiation: 3 LifeMap Cells 
    NameCategory
    White adipocyte-like cells (Differentiation of ...)Adipose
    HyStem+BMP4-induced 7SMOO32 cells (HyStem+BMP4 inductio...)Adipose
    HyStem+BMP4-induced E15 cells (HyStem+BMP4 inductio...)Adipose, Bone, Cartilage

    See CIDEC Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for CIDEC

    SOURCE GeneReport for Unigene cluster: Hs.567562

    UniProtKB/Swiss-Prot: CIDEC_HUMAN, Q96AQ7
    Tissue specificity: Expressed mainly in adipose tissue, small intestine, heart, colon and stomach and, at lower levels,
    in brain, kidney and liver

        SABiosciences Expression via Pathway-Focused PCR Array including CIDEC: 
              Apoptosis 384HT in human mouse rat

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CIDEC

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for CIDEC gene from 4/13 species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    chicken
    (Gallus gallus)
    Aves LOC1008597331 cell death activator CIDE-3-like 66.97(n)
    63.68(a)
      100859733  XM_003641931.1  XP_003641979.1 
    lizard
    (Anolis carolinensis)
    Reptilia CIDEC6
    --
    55(a)
    1 ↔ 1
    GL343417.1(33473-35038)
    African clawed frog
    (Xenopus laevis)
    Amphibia CA987523.12   -- 75.49(n)    CA987523.1 
    zebrafish
    (Danio rerio)
    Actinopterygii si:dkey-91f15.61 si:dkey-91f15.6 57.08(n)
    52.36(a)
      564304  NM_001045047.1  NP_001038512.1 


    ENSEMBL Gene Tree for CIDEC (if available)
    TreeFam Gene Tree for CIDEC (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for CIDEC gene
    CIDEB2  CIDEA2  
    2 SIMAP similar genes for CIDEC using alignment to 2 protein entries:     CIDEC_HUMAN (see all proteins):
    CIDEA    CIDEB

    CIDEC for paralogs           About GeneDecksing


    3 Pseudogenes.org Pseudogenes for CIDEC
    PGOHUM00000240016 PGOHUM00000237528 PGOHUM00000238176


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/293 NCBI SNPs in CIDEC are shown (see all 293    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 3 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1446162261,2
    --9907975(+) TTAGAA/GGAGTG 4 -- ds50010--------
    rs1466512671,2
    --9907995(+) CACCTC/GCTCAA 4 -- ds50010--------
    rs1845981171,2
    --9908174(+) CTCCTC/GGTCTC 4 -- ds50010--------
    rs1489057341,2
    C,--9908241(+) GTGCCC/TAGCTG 4 -- ds50010--------
    rs1136071371,2
    C--9908247(+) AGCTG-/TTTTTT 4 -- ds50011Minor allele frequency- T:0.00CSA 2
    rs738115971,2
    C,--9908284(+) CATTAG/CCTGTA 4 -- ds50011Minor allele frequency- C:0.50WA 2
    rs1480469251,2
    --9908294(+) AATCCC/TACATT 4 -- ds50010--------
    rs1895127111,2
    --9908306(+) AAGAGA/CATACT 4 -- ds50010--------
    rs1811494661,2
    --9908326(+) GATTCA/GTCTCT 4 -- ds50010--------
    rs1417250461,2
    --9908352(+) CAACCC/TTCCAG 4 -- ds50010--------

    HapMap Linkage Disequilibrium report for CIDEC (9908398 - 9921938 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for CIDEC: --
    Human Gene Mutation Database (HGMD): CIDEC

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CIDEC
    DNA2.0 Custom Variant and Variant Library Synthesis for CIDEC

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    CIDEC for disorders           About GeneDecksing

    OMIM gene information: 612120    OMIM disorders: --

    UniProtKB/Swiss-Prot: CIDEC_HUMAN, Q96AQ7
  • Note=In omental adipose tissue of obese patients matched for BMI, expression levels tend to correlate with
  • insulin sensitivity. Expression is increased 2-3 fold in the group of patients with high insulin sensitivity, compared
    to the insulin-resistant group. This observation is consistent with the idea that triglyceride storage in adipocytes
    plays an important role in sequestering triglycerides and fatty acids away from the circulation and peripheral
    tissues, thus enhancing insulin sensitivity in liver and muscle. This effect is not significant in subcutaneous
    adipose tissue (PubMed:18509062). In subcutaneous adipose tissue of diabetic patients, tends to negatively correlate
    with body mass index and total fat mass, independently of insulin sensitivity (PubMed:18334488)

    6 diseases for CIDEC:    About MalaCards
    insulin resistance    panniculitis    metabolic disorders    lipodystrophy
    obesity    hepatitis


    Export disorders for CIDEC gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for CIDEC gene, integrated from 9 sources (see all 27):
    (articles sorted by number of sources associating them with CIDEC)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Molecular cloning and characterization of CIDE-3, a novel member of the cell-death-inducing DNA-fragmentation-factor (DFF45)-like effector family. (PubMed id 12429024)1, 2, 3, 9 Liang L.... Li T. (2003)
    2. Functional analysis of FSP27 protein regions for lipi d droplet localization, caspase-dependent apoptosis, and dimerization with CIDE A. (PubMed id 19843876)1, 2, 9 Liu K....Smas C.M. (2009)
    3. Fat-specific protein 27 regulates storage of triacylglycerol. (PubMed id 18334488)1, 2, 9 Keller P....MacDougald O.A. (2008)
    4. Cidea is associated with lipid droplets and insulin sensitivity in humans. (PubMed id 18509062)1, 2 Puri V....Czech M.P. (2008)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    6. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    7. Hepatic expression of cell death-inducing DFFA-like e ffector C in obese subjects is reduced by marked weight loss. (PubMed id 19661960)1, 9 Hall A.M....Finck B.N. (2010)
    8. Differential regulation of CIDEA and CIDEC expression by insulin via Akt1/2- and JNK2-dependent pathways in human adipocytes. (PubMed id 21636835)1 Ito M....Murakami K. (2011)
    9. Which CIDE are you on? Apoptosis and energy metabolis m. (PubMed id 20967381)1 Yonezawa T....Inoko H. (2011)
    10. Human cell-death-inducing DFF45-like effector C induc es apoptosis via caspase-8. (PubMed id 21865223)1 Tang X....Zhao M. (2011)

    (in PubMed, OMIM, and NCBI Bookshelf)
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    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 63924 HGNC: 24229 AceView: CIDEC Ensembl:ENSG00000187288 euGenes: HUgn63924
    ECgene: CIDEC H-InvDB: CIDEC

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for CIDEC Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for CIDEC gene:
    Search GeneIP for patents involving CIDEC

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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