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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

CIDEC Gene

protein-coding   GIFtS: 51
GCID: GC03M009908

Cell Death-Inducing DFFA-Like Effector C

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

Aliases
Cell Death-Inducing DFFA-Like Effector C1 2     Cell Death Activator CIDE-32
FSP272 3 5     Fat Specific Protein 272
CIDE-32     Cell Death-Inducing DFFA-Like Effector Protein C3
CIDE32     Fat-Specific Protein FSP27 Homolog3
FPLD52     CIDEX5

External Ids:    HGNC: 242291   Entrez Gene: 639242   Ensembl: ENSG000001872887   OMIM: 6121205   UniProtKB: Q96AQ73   

Export aliases for CIDEC gene to outside databases

Previous GC identifers: GC03M009884 GC03M009844


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

Entrez Gene summary for CIDEC Gene:
This gene encodes a member of the cell death-inducing DNA fragmentation factor-like effector family. Members of
this family play important roles in apoptosis. The encoded protein promotes lipid droplet formation in adipocytes
and may mediate adipocyte apoptosis. This gene is regulated by insulin and its expression is positively
correlated with insulin sensitivity. Mutations in this gene may contribute to insulin resistant diabetes. A
pseudogene of this gene is located on the short arm of chromosome 3. Alternatively spliced transcript variants
that encode different isoforms have been observed for this gene. (provided by RefSeq, Dec 2010)

GeneCards Summary for CIDEC Gene: 
CIDEC (cell death-inducing DFFA-like effector c) is a protein-coding gene. Diseases associated with CIDEC include panniculitis, and insulin resistance. GO annotations related to this gene include molecular_function. An important paralog of this gene is CIDEA.

UniProtKB/Swiss-Prot: CIDEC_HUMAN, Q96AQ7
Function: May act as a CEBPB coactivator in white adipose tissue to control the expression of a subset of CEBPB
downstream target genes, including SOCS1, SOCS3, TGFB1, TGFBR1, ID2 and XDH (By similarity). Binds to lipid
droplets and regulates their enlargement, thereby restricting lipolysis and favoring storage. At focal contact
sites between lipid droplets, promotes directional net neutral lipid transfer from the smaller to larger lipid
droplets. The transfer direction may be driven by the internal pressure difference between the contacting lipid
droplet pair. When overexpressed in preadipocytes, induces apoptosis or increases cell susceptibility to
apoptosis induced by serum deprivation or TGFB treatment. As mature adipocytes, that express high CIDEC levels,
are quite resistant to apoptotic stimuli, the physiological significance of its role in apoptosis is unclear




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 73), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000003.11  NT_022517.18  NC_018914.2  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the CIDEC gene promoter:
         AP-1   ATF-2   MyoD   c-Jun   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 5): CIDEC promoter sequence
   Search SABiosciences Chromatin IP Primers for CIDEC

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CIDEC


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 3p25.3   Ensembl cytogenetic band:  3p25.3   HGNC cytogenetic band: 3p25

CIDEC Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CIDEC gene location

GeneLoc information about chromosome 3         GeneLoc Exon Structure

GeneLoc location for GC03M009908:  view genomic region     (about GC identifiers)

Start:
9,908,394 bp from pter      End:
9,921,938 bp from pter
Size:
13,545 bases      Orientation:
minus strand

(According to UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MAXQB RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Ontologies according to Gene Ontology Consortium 01 Oct 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, and/or Cloud-Clone Corp.)
About This Section

UniProtKB/Swiss-Prot: CIDEC_HUMAN, Q96AQ7 (See protein sequence)
Recommended Name: Cell death activator CIDE-3  
Size: 238 amino acids; 26754 Da
Subunit: Interacts with CEBPB (By similarity). Interacts with CIDEA
Subcellular location: Nucleus (By similarity). Endoplasmic reticulum (By similarity). Lipid droplet. Note=Diffuses
quickly on lipid droplet surface, but becomes trapped and clustered at lipid droplet contact sites, thereby
enabling its rapid enrichment at lipid droplet contact sites
Secondary accessions: C9JMN7 Q67DW9 Q9GZY9
Alternative splicing: 4 isoforms:  Q96AQ7-1   Q96AQ7-2   Q96AQ7-3   Q96AQ7-4   (No experimental confirmation available)

Explore the universe of human proteins at neXtProt for CIDEC: NX_Q96AQ7

Explore proteomics data for CIDEC at MOPED 

Post-translational modifications:

  • UniProtKB: Ubiquitinated and targeted to proteasomal degradation, resulting in a short half-life. Protein stability depends
    on triaclyglycerol synthesis, fatty acid availability and lipid droplet formation (By similarity)
  • View modification sites using PhosphoSitePlus
  • View neXtProt modification sites for NX_Q96AQ7

  • CIDEC Protein expression data from MOPED1, PaxDb2 and MAXQB3 :    About this image 

    CIDEC Protein Expression
    REFSEQ proteins (4 alternative transcripts): 
    NP_001186480.1  NP_001186481.1  NP_001186552.1  NP_071377.2  

    ENSEMBL proteins: 
     ENSP00000338642   ENSP00000392975   ENSP00000400649   ENSP00000408631   ENSP00000411356  
     ENSP00000373328  

    Human Recombinant Protein Products for CIDEC: 
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    Browse Sino Biological Cell Lysates 
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    Cloud-Clone Corp. Proteins for CIDEC 

    Gene Ontology (GO): 5/7 cellular component terms (GO ID links to tree view) (see all 7):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular ----
    GO:0005634nucleus IDA--
    GO:0005737cytoplasm IDA--
    GO:0005783endoplasmic reticulum IEA--
    GO:0005811lipid particle IEA--

    CIDEC for ontologies           About GeneDecksing



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    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section
    1 InterPro protein domain:
     IPR003508 CAD

    Graphical View of Domain Structure for InterPro Entry Q96AQ7

    ProtoNet protein and cluster: Q96AQ7

    1 Blocks protein domain: IPB003508 Caspase-activated nuclease CIDE-N

    UniProtKB/Swiss-Prot: CIDEC_HUMAN, Q96AQ7
    Similarity: Contains 1 CIDE-N domain


    CIDEC for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase, shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Sirion Biotech, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, Vector BioLabs, and Sirion Biotech, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene.)
    About This Section

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: CIDEC_HUMAN, Q96AQ7
    Function: May act as a CEBPB coactivator in white adipose tissue to control the expression of a subset of CEBPB
    downstream target genes, including SOCS1, SOCS3, TGFB1, TGFBR1, ID2 and XDH (By similarity). Binds to lipid
    droplets and regulates their enlargement, thereby restricting lipolysis and favoring storage. At focal contact
    sites between lipid droplets, promotes directional net neutral lipid transfer from the smaller to larger lipid
    droplets. The transfer direction may be driven by the internal pressure difference between the contacting lipid
    droplet pair. When overexpressed in preadipocytes, induces apoptosis or increases cell susceptibility to
    apoptosis induced by serum deprivation or TGFB treatment. As mature adipocytes, that express high CIDEC levels,
    are quite resistant to apoptotic stimuli, the physiological significance of its role in apoptosis is unclear

         Gene Ontology (GO): 1 molecular function term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0003674molecular_function ND--
         
    CIDEC for ontologies           About GeneDecksing


    Phenotypes:
         1 GenomeRNAi human phenotype for CIDEC:
     Increased circadian rhythm amp 

         6 MGI mutant phenotypes (inferred from 2 alleles(MGI details for Cidec):
     adipose tissue  behavior/neurological  growth/size  homeostasis/metabolism  integument 
     liver/biliary system 

    CIDEC for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-outs for CIDEC: Cidectm1Maka Cidectm1Pli

       inGenious Targeting Laboratory - Custom generated mouse model solutions for CIDEC 
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    hsa-miR-491-5p hsa-miR-486-3p
    SwitchGear 3'UTR luciferase reporter plasmidCIDEC 3' UTR sequence
    Inhib. RNA
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    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Oct 2013 via Entrez Gene).
    About This Section




    Interactions:

        Search SABiosciences Gene Network CentralTM Interacting Genes and Proteins Networks for CIDEC

    2 Interacting proteins for CIDEC (Q96AQ73) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    CIDEAO605433I2D: score=1 
    KIAA1279Q96EK53I2D: score=1 
    About this table

    Gene Ontology (GO): 5 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006351transcription, DNA-dependent IEA--
    GO:0006355regulation of transcription, DNA-dependent IEA--
    GO:0006915apoptotic process IDA12429024
    GO:0034389lipid particle organization IMP--
    GO:0097194execution phase of apoptosis IDA12429024

    CIDEC for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for CIDEC

    Search CenterWatch for drugs/clinical trials and news about CIDEC

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    Conferences by KenesGroup, exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Sirion Biotech, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for CIDEC gene (4 alternative transcripts): 
    NM_001199551.1  NM_001199552.1  NM_001199623.1  NM_022094.3  

    Unigene Cluster for CIDEC:

    Cell death-inducing DFFA-like effector c
    Hs.567562  [show with all ESTs]
    Unigene Representative Sequence: AF303893
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000336832(uc010hcp.3 uc003btp.3 uc003btq.3 uc021wsv.1 uc021wsw.1)
    ENST00000455015(uc003btr.3) ENST00000423850(uc003bto.3 uc003bts.3)
    ENST00000430427 ENST00000443115 ENST00000487454 ENST00000383817
    miRNA
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    2 QIAGEN miScript miRNA Assays for microRNAs that regulate CIDEC:
    hsa-miR-491-5p hsa-miR-486-3p
    SwitchGear 3'UTR luciferase reporter plasmidCIDEC 3' UTR sequence
    Inhib. RNA
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    Additional mRNA sequence: 

    AF303893.1 AK024524.1 AK024530.1 AY364638.1 AY364640.1 BC016851.1 

    5 DOTS entries:

    DT.95162686  DT.75104170  DT.100788704  DT.86845992  DT.100788703 

    24/43 AceView cDNA sequences (see all 43):

    CD244693 BQ694634 CD558840 CD518776 NM_022094 AF303893 BG740660 AY364640 
    AL598731 CD519587 BM991792 AK024524 CD517657 BG696770 AY364638 CD517940 
    CB268955 AL598630 BQ694583 AK024530 AI460316 CD518729 BQ695178 CB269236 

    GeneLoc Exon Structure

    5 Alternative Splicing Database (ASD) splice patterns (SP) for CIDEC    About this scheme

    ExUns: 1 ^ 2a · 2b ^ 3 ^ 4 ^ 5 ^ 6 ^ 7a · 7b · 7c · 7d · 7e
    SP1:                          -                                             
    SP2:                                                                        
    SP3:                    -     -                                             
    SP4:                          -                                             
    SP5:                          -     -     -                                 


    ECgene alternative splicing isoforms for CIDEC

    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    CIDEC expression in normal human tissues (normalized intensities)      CIDEC embryonic expression: see
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TGATATTAGG
    CIDEC Expression
    About this image


    CIDEC expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database 
     5/13 selected tissues (see all 13) fully expand
     
     Adipose (Muscoskeletal System)    fully expand to see all 11 entries
             Body Subcutaneous White Adipose
             HyStem+BMP4-induced E15 cells
             Human Preadipocyte-visceral (HPA-v)   
             adipose tissue   
     
     Fibroblast (Uncategorized)    fully expand to see all 3 entries
             Human Prostate Fibroblasts (HPrF)   
     
     Cartilage (Muscoskeletal System)    fully expand to see all 2 entries
             HyStem+BMP4-induced E15 cells
             synovial membrane   
     
     Skeletal Muscle (Muscoskeletal System)    fully expand to see all 2 entries
             Human Skeletal Muscle Myoblast (HSkMM)   
     
     Smooth Muscle (Muscoskeletal System)
             Human Tracheal Smooth Muscle Cells (HTSMC)   

    See CIDEC Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for CIDEC

    SOURCE GeneReport for Unigene cluster: Hs.567562

    UniProtKB/Swiss-Prot: CIDEC_HUMAN, Q96AQ7
    Tissue specificity: Expressed mainly in adipose tissue, small intestine, heart, colon and stomach and, at lower
    levels, in brain, kidney and liver

        SABiosciences Expression via Pathway-Focused PCR Array including CIDEC: 
              Apoptosis 384HT in human mouse rat

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    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CIDEC

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for CIDEC gene from 5/13 species (see all 13)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Cidec1 , 5 cell death-inducing DFFA-like effector c1, 5 81.65(n)1
    79.83(a)1
      6 (52.76 cM)5
    143111  NM_178373.31  NP_848460.11 
     1134246345 
    chicken
    (Gallus gallus)
    Aves LOC1008597331 cell death activator CIDE-3-like 66.97(n)
    63.68(a)
      100859733  XM_003641931.1  XP_003641979.1 
    lizard
    (Anolis carolinensis)
    Reptilia CIDEC6
    cell death-inducing DFFA-like effector c
    56(a)
    1 ↔ 1
    GL343417.1(29555-37782)
    African clawed frog
    (Xenopus laevis)
    Amphibia CA987523.12   -- 75.49(n)    CA987523.1 
    zebrafish
    (Danio rerio)
    Actinopterygii si:dkey-91f15.61 si:dkey-91f15.6 57.08(n)
    52.36(a)
      564304  NM_001045047.1  NP_001038512.1 


    ENSEMBL Gene Tree for CIDEC (if available)
    TreeFam Gene Tree for CIDEC (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for CIDEC gene
    CIDEA2  CIDEB2  
    2 SIMAP similar genes for CIDEC using alignment to 2 protein entries:     CIDEC_HUMAN (see all proteins):
    CIDEA    CIDEB

    CIDEC for paralogs           About GeneDecksing


    3 Pseudogenes.org Pseudogenes for CIDEC
    PGOHUM00000240016 PGOHUM00000237528 PGOHUM00000238176


    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/368 SNPs in CIDEC are shown (see all 368)    About this table     
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 3 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1446162261,2
    --9907975(+) TTAGAA/GGAGTG 4 -- ds50010--------
    rs1466512671,2
    --9907995(+) CACCTC/GCTCAA 4 -- ds50010--------
    rs1845981171,2
    C--9908174(+) CTCCTC/GGTCTC 4 -- ds50010--------
    rs1489057341,2
    C--9908241(+) GTGCCC/TAGCTG 4 -- ds50010--------
    rs1136071371,2
    C--9908247(+) AGCTG-/TTTTTT 4 -- ds50011Minor allele frequency- T:0.00CSA 2
    rs738115971,2
    C,F--9908284(+) CATTAG/CCTGTA 4 -- ds50011Minor allele frequency- C:0.50WA 2
    rs1480469251,2
    --9908294(+) AATCCC/TACATT 4 -- ds50010--------
    rs1895127111,2
    --9908306(+) AAGAGA/CATACT 4 -- ds50010--------
    rs1811494661,2
    --9908326(+) GATTCA/GTCTCT 4 -- ds50010--------
    rs1417250461,2
    --9908352(+) CAACCC/TTCCAG 4 -- ds50010--------

    HapMap Linkage Disequilibrium report for CIDEC (9908394 - 9921938 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 4 variations for CIDEC:    About this table     
    Variant IDTypeSubtypePubMed ID
    esv2724890CNV Deletion23290073
    esv2666111CNV Deletion23128226
    nsv821983CNV Loss20364138
    nsv834615CNV Loss17160897


    Human Gene Mutation Database (HGMD): CIDEC
    SABiosciences Cancer Mutation PCR Assays
    SeqTarget long-range PCR primers for resequencing CIDEC
    DNA2.0 Custom Variant and Variant Library Synthesis for CIDEC

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Conferences by KenesGroup, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section
    OMIM gene information: 612120    OMIM disorders: --

    UniProtKB/Swiss-Prot: CIDEC_HUMAN, Q96AQ7
  • Note=In omental adipose tissue of obese patients matched for BMI, expression levels tend to correlate
    with insulin sensitivity. Expression is increased 2-3 fold in the group of patients with high insulin
    sensitivity, compared to the insulin-resistant group. This observation is consistent with the idea that
    triglyceride storage in adipocytes plays an important role in sequestering triglycerides and fatty acids away
    from the circulation and peripheral tissues, thus enhancing insulin sensitivity in liver and muscle. This effect
    is not significant in subcutaneous adipose tissue (PubMed:18509062). In subcutaneous adipose tissue of diabetic
    patients, tends to negatively correlate with body mass index and total fat mass, independently of insulin
    sensitivity (PubMed:18334488)

  • 6 diseases for CIDEC:    About MalaCards
    panniculitis    insulin resistance    lipodystrophy    metabolic disorders
    obesity    hepatitis


    CIDEC for disorders           About GeneDecksing


    Export disorders for CIDEC gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for CIDEC gene, integrated from 9 sources (see all 30):
    (articles sorted by number of sources associating them with CIDEC)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Molecular cloning and characterization of CIDE-3, a novel member of the cell-death-inducing DNA-fragmentation-factor (DFF45)-like effector family. (PubMed id 12429024)1, 2, 3, 9 Liang L.... Li T. (2003)
    2. Functional analysis of FSP27 protein regions for lipi d droplet localization, caspase-dependent apoptosis, and dimerization with CIDE A. (PubMed id 19843876)1, 2, 9 Liu K....Smas C.M. (2009)
    3. Fat-specific protein 27 regulates storage of triacylglycerol. (PubMed id 18334488)1, 2, 9 Keller P....MacDougald O.A. (2008)
    4. Cidea is associated with lipid droplets and insulin sensitivity in humans. (PubMed id 18509062)1, 2 Puri V....Czech M.P. (2008)
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    6. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    7. Hepatic expression of cell death-inducing DFFA-like e ffector C in obese subjects is reduced by marked weight loss. (PubMed id 19661960)1, 9 Hall A.M....Finck B.N. (2010)
    8. Fat-specific protein 27 modulates nuclear factor of ac tivated T cells 5 and the cellular response to stress. (PubMed id 23233732)1 Ueno M....Kraemer F.B. (2013)
    9. VCP phosphorylation-dependent interaction partners pre vent apoptosis in Helicobacter pylori-infected gastric epithelial cells. (PubMed id 23383273)1 Yu C.C....Chow L.P. (2013)
    10. Fsp27/CIDEC is a CREB target gene induced during early fasting in liver and regulated by FA oxidation rate. (PubMed id 23220584)1 Vila-Brau A....Marrero P.F. (2013)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
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      Query String
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    OMIM
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      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 63924 HGNC: 24229 AceView: CIDEC Ensembl:ENSG00000187288 euGenes: HUgn63924
    ECgene: CIDEC H-InvDB: CIDEC

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for CIDEC Pharmacogenomics, SNPs, Pathways

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for CIDEC gene:
    Search GeneIP for patents involving CIDEC

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



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    GeneCards Homepage - Last full update: 23 Oct 2013 - Incrementals: 4 Nov 2013 , 7 Nov 2013 , 23 Jan 2014

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