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Category   Symbol Source: HGNC EntrezGene Ensembl GeneCards RNA genes CroW21
GIFtS

CIDEB Gene

protein-coding   GIFtS: 51
GCID: GC14M024774

cell death-inducing DFFA-like effector b

 Explore 8 diseases affiliated with
CIDEB via our new
 Human Malady Compendium 
Biological research products
for CIDEB
    

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, and/or 10fRNAdb)
About This Section

Aliases
Cell Death-Inducing DFFA-Like Effector B1 2 3
Cell Death Activator CIDE-B2

External Ids:    HGNC: 19771   Entrez Gene: 271412   Ensembl: ENSG000001363057   OMIM: 6044415   UniProtKB: Q9UHD43   

Export aliases for CIDEB gene to outside databases

Previous GC identifers: GC14M022146 GC14M018561 GC14M022764 GC14M023844 GC14M004889


(According to Entrez Gene, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

UniProtKB/Swiss-Prot: CIDEB_HUMAN, Q9UHD4
Function: Activates apoptosis




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 69), Regulatory elements and Epigenetics data according to QIAGEN, SABiosciences, and/or SwitchGear Genomics)
About This Section
RefSeq DNA sequence:
NC_000014.8  NC_018925.1  NT_026437.12  
Regulatory elements:
   SABiosciences Regulatory transcription factor binding sites in the CIDEB gene promoter:
         GR   Pax-5   YY1   GATA-1   c-Ets-1   HNF-4alpha1   PPAR-alpha   CREB   COMP1   GR-alpha   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): CIDEB promoter sequence
   Search SABiosciences Chromatin IP Primers for CIDEB

Epigenetics:
QIAGEN PyroMark CpG Assay predesigned Pyrosequencing DNA Methylation assays in human, mouse, rat CIDEB


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 14q12   Ensembl cytogenetic band:  14q12   HGNC cytogenetic band: 14q12

CIDEB Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CIDEB gene location

GeneLoc information about chromosome 14         GeneLoc Exon Structure

GeneLoc location for GC14M024774:  view genomic region     (about GC identifiers)

Start:
24,774,302 bp from pter      End:
24,780,655 bp from pter
Size:
6,354 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, neXtProt, Ensembl, and/or Reactome, Modification sites according to 2PhosphoSitePlus, Specific Peptides from DME, Protein expression images according to data from SPIRE MOPED and PaxDb, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Uscn,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Uscn, Ontologies according to Gene Ontology Consortium 01 Mar 2013 and Entrez Gene, Antibodies by EMD Millipore, R&D Systems, GenScript, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, Abcam, and/or Uscn)
About This Section

UniProtKB/Swiss-Prot: CIDEB_HUMAN, Q9UHD4 (See protein sequence)
Recommended Name: Cell death activator CIDE-B  
Size: 219 amino acids; 24678 Da
Subunit: Inhibited by DFFB. Interacts with DFFA and DFFB
1 PDB 3D structure from and Proteopedia for CIDEB:
1D4B (3D)    
Secondary accessions: D3DS73 Q546V8 Q9NNW9

Explore the universe of human proteins at neXtProt for CIDEB: NX_Q9UHD4

Post-translational modifications:

  • View modification sites using PhosphoSitePlus2
  • View neXtProt modification sites for NX_Q9UHD4

  • CIDEB Protein expression data from MOPED and PaxDb:    About this image 
    Estimated protein expression log10 (pmol).

    REFSEQ proteins: NP_055245.2  
    ENSEMBL proteins: 
     ENSP00000451089   ENSP00000337731   ENSP00000258807   ENSP00000451744   ENSP00000444233  

    Human Recombinant Protein Products: 
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    OriGene Protein Over-expression Lysate: CIDEB
    OriGene Custom Protein Services for CIDEB 
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    Novus Biologicals CIDEB Proteins
    Novus Biologicals CIDEB Lysate
    Browse Sino Biological Recombinant Proteins
    Browse ProSpec Recombinant Proteins
    Uscn Proteins for CIDEB

    Gene Ontology (GO): 1 cellular component term (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005829cytosol IDA12429024


    CIDEB for ontologies           About GeneDecksing



    CIDEB Antibody Products: 
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    Uscn Antibodies for CIDEB
    ThermoFisher Antibodies for CIDEB

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    Browse Kits and Assays available from EMD Millipore
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    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for CIDEB
    Browse Enzo Life Sciences for kits & assays
    Uscn ELISAs and CLIAs for CIDEB


    (According to InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    CIDEB for domains           About GeneDecksing

    1 InterPro domain/family:
     IPR003508 CAD

    Graphical View of Domain Structure for InterPro Entry Q9UHD4

    ProtoNet protein and cluster: Q9UHD4

    1 Blocks protein family: IPB003508 Caspase-activated nuclease CIDE-N

    UniProtKB/Swiss-Prot: CIDEB_HUMAN, Q9UHD4
    Similarity: Contains 1 CIDE-N domain


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013,
    bound targets from SABiosciences, miRNA Gene Targets from miRTarBase shRNA from OriGene, RNAi from EMD Millipore, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, SwitchGear Genomics, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, LifeMap BioReagents, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene.)
    About This Section

    Function Summary:

         UniProtKB/Swiss-Prot: CIDEB_HUMAN, Q9UHD4
    Function: Activates apoptosis

         Genatlas biochemistry entry for CIDEB:
    cell death-inducing DFFA-like effector B,interacting with the DFFA/DFFB complex and putatively involved in apoptotic
    DNA fragmentation

    miRNA
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    Browse MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat CIDEB
    3 QIAGEN miScript miRNA Assays for microRNAs that regulate CIDEB:
    hsa-miR-194* hsa-miR-1179 hsa-miR-3150a-3p
    SwitchGear 3'UTR luciferase reporter plasmidCIDEB 3' UTR sequence
    Inhib. RNA
    Products:
        
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CIDEB (see all 7)
    OriGene shRNA RFP: CIDEB
    Browse OriGene siRNA
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CIDEB

    Gene Editing
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    DNA2.0 Custom Protein Engineering Service for CIDEB

    Clone
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    Browse Clones for the Expression of Recombinant Proteins Available from EMD Millipore
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CIDEB (see all 3)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CIDEB (see all 2)
    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector: CIDEB (NM_014430)
    Browse Sino Biological Human cDNA Clones
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    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CIDEB 

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    Search LifeMap BioReagents cell lines for CIDEB

    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CIDEB

    Animal Models:
         Mouse knock-out Cidebtm1Pli for CIDEB
         7 MGI mutant phenotypes (inferred from 1 allele(MGI details for Cideb):
     adipose tissue  behavior/neurological  growth/size  hematopoietic system  homeostasis/metabolism 
     immune system  liver/biliary system 

    CIDEB for phenotypes           About GeneDecksing


    (Pathways according to EMD Millipore, R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to SABiosciences, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Mar 2013 via Entrez Gene).
    About This Section



    Interactions:

        SABiosciences Gene Network CentralTM Interacting Genes and Proteins Network for CIDEB

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    4 Interacting proteins for CIDEB (Q9UHD43 ENSP000002588074) via UniProtKB, MINT, STRING, and/or I2D
    InteractantInteraction Details
    GeneCardExternal ID(s)
    DFFAO002733I2D: score=2 
    DFFBO760753I2D: score=2 
    CIDEAO605433I2D: score=1 
    --ensp: ENSP000003377314STRING: ensp: ENSP00000337731
    About this table

    Gene Ontology (GO): 3 biological process terms (GO ID links to tree view):    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006915apoptotic process ----
    GO:0006917induction of apoptosis IDA12429024
    GO:0008630intrinsic apoptotic signaling pathway in response to DNA damage TAS10619428


    CIDEB for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience HMDB, BitterDB, and/or Novoseek, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB, with drugs/clinical trials/news search links to CenterWatch)
    About This Section
    Browse Small Molecules at EMD Millipore
    Browse drugs & compounds from Enzo Life Sciences

    Browse Tocris compounds for CIDEB
    Search CenterWatch for drugs/clinical trials and news about CIDEB 

    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 235 Homo sapiens; Mar 10 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    RNAi Products from EMD Millipore,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN,
    Tagged/untagged cDNA clones from OriGene, SwitchGear Genomics, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, SABiosciences, and/or QIAGEN )
    About This Section

    REFSEQ mRNAs for CIDEB gene: 
    NM_014430.2  

    Unigene Cluster for CIDEB:

    Cell death-inducing DFFA-like effector b
    Hs.708040  [show with all ESTs]
    Unigene Representative Sequence: AB095941
    7 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000554411(uc001won.3) ENST00000336557(uc001wop.3) ENST00000258807(uc001woo.3)
    ENST00000556756 ENST00000555471 ENST00000555817 ENST00000541830

    miRNA
    Products:
         
    OriGene 3'-UTR Clone: CIDEB
    Browse OriGene MicroRNA Expression Plasmids
    QIAGEN Custom miScript Target Protector blocks miRNA-binding site of human, mouse, rat CIDEB
    3 QIAGEN miScript miRNA Assays for microRNAs that regulate CIDEB:
    hsa-miR-194* hsa-miR-1179 hsa-miR-3150a-3p
    SwitchGear 3'UTR luciferase reporter plasmidCIDEB 3' UTR sequence
    Inhib. RNA
    Products:
         
    Browse for Gene Knock-down Tools from EMD Millipore
    OriGene 29mer shRNA kits in GFP-retroviral vector in human, mouse, rat for CIDEB (see all 7)
    OriGene shRNA RFP: CIDEB
    Browse OriGene siRNA
    QIAGEN FlexiTube/FlexiPlate siRNA for gene silencing in human, mouse, rat CIDEB
    Clone
    Products:
         
    OriGene Myc/DDK tagged cDNA clones in CMV expression vector in human, mouse, rat for CIDEB (see all 3)
    OriGene untagged cDNA clones in CMV expression vector in human, mouse, rat for CIDEB (see all 2)
    OriGene custom cloning services – gene synthesis, subcloning, mutagenesis, variant library, vector shuttling 
    GenScript: all cDNA clones in your preferred vector: CIDEB (NM_014430)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CIDEB
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CIDEB 
    Primer
    Products:
        
    OriGene genome-wide validated SYBR primer pairs in human, mouse, rat for CIDEB
    Browse OriGene validated miRNA SYBR primer pairs
    SABiosciences RT2 qPCR Primer Assay in human, mouse, rat CIDEB
      QIAGEN QuantiTect SYBR Green Assays in human, mouse, rat CIDEB
      QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CIDEB

    Additional cDNA sequence: 

    AB095941.1 AF218586.1 AK025512.1 AK123717.1 BC015481.1 BC025332.1 BX248018.1 BX647311.1 

    11 DOTS entries:

    DT.99940351  DT.112192  DT.120794999  DT.97814886  DT.101957605  DT.100649365  DT.120794964  DT.100028268 
    DT.120794997  DT.91757315  DT.95179099 

    24/99 AceView cDNA sequences (see all 99):

    CR611009 BC000982 BE206519 BF925719 CB157532 BC035970 CB162472 AF218586 
    AA922235 AI017820 CA438265 AA810119 BQ706362 CD245652 AW024578 BX113973 
    BM981976 AI364596 AA424820 BX431517 AW450782 AF544398 AK000387 AA236401 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, plus additional links to Genevestigator, and/or SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from SABiosciences, Primers from OriGene, SABiosciences, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    CIDEB expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS
    CGAP TAG: TAAAAGGATG

    Microarray
    RNAseq (Illumina Body Map)
    (100×FPKM)½
    SAGE (Serial Analysis of Gene Expression)

    About this image

    CIDEB expression in embryonic tissues and stem cells
    Expression by the Database of Embryonic development, Stem cell research, and Regenerative medicine    About this table
    6 LifeMap In Vivo Development Anatomical Compartments/Cells 
    Tissue Anatomical Compartment CellCategory (developmental path)
    KidneyDistal TubuleDistal Tubule CellsKidney
    KidneyLoop of HenleLoop of Henle CellsKidney
    KidneyDistal TubuleKidney
    KidneyEpithelial TubuleKidney
    KidneyLoop of HenleKidney
    KidneyMetanephrosKidney
    Expression: Positive    Negative     Selective marker
    Experimental details: Curated     Microarrays     In-situ hybridization
    Stem Cell Differentiation: 1 LifeMap Cell 
    NameCategory
    PureStem™ endothelial progenitor 30-MV2-12 (Embryonic Progenitor Cell)Blood, Endothelium

    See CIDEB Protein Expression from SPIRE MOPED and PaxDB
    Genevestigator expression for CIDEB

    SOURCE GeneReport for Unigene cluster: Hs.708040

    UniProtKB/Swiss-Prot: CIDEB_HUMAN, Q9UHD4
    Tissue specificity: Highly expressed in liver and small intestine and, at lower levels, in colon, kidney and spleen

        SABiosciences Expression via Pathway-Focused PCR Arrays including CIDEB: 
              Neurotoxicity in human mouse rat
              Apoptosis 384HT in human mouse rat
              Apoptosis in human mouse rat

    Primer
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    QIAGEN QuantiFast Probe-based Assays in human, mouse, rat CIDEB
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CIDEB

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    This gene was present in the common ancestor of chordates.

    Orthologs for CIDEB gene from 3/8 species (see all 8)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Cideb1 , 5 cell death-inducing DNA fragmentation factor, alpha more1, 5 83.33(n)1
    86.11(a)1
      14 (28.19 cM)5
    126841  NM_009894.31  NP_034024.21 
     557540455 
    lizard
    (Anolis carolinensis)
    Reptilia CIDEB6
    --
    61(a)
    1 ↔ 1
    GL343400.1(253218-258285)
    zebrafish
    (Danio rerio)
    Actinopterygii cideb1 cell death-inducing DFFA-like effector b 56.48(n)
    50.26(a)
      553467  XM_002662822.1  XP_002662868.1 


    ENSEMBL Gene Tree for CIDEB (if available)
    TreeFam Gene Tree for CIDEB (if available) 

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section
    Paralogs for CIDEB gene
    CIDEA2  CIDEC2  
    2 SIMAP similar genes for CIDEB using alignment to 2 protein entries:     CIDEB_HUMAN (see all proteins):
    CIDEA    CIDEC

    CIDEB for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD) and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers from QIAGEN, Cancer Mutation PCR Arrays and Assays and Copy Number PCR Arrays from SABiosciences)
    About This Section

    10/96 NCBI SNPs in CIDEB are shown (see all 96    About this table
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 14 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1148550001,2
    C,--24774336(+) GGGGAG/AGGCAA 2 -- int1 ut311Minor allele frequency- A:0.01WA 118
    rs590842571,2
    C,F,--24774338(+) GGAGGA/C/GCAAAA 3 -- int1 ut314WA CSA 123
    rs1392714941,2
    --24774378(+) TTAAAC/TTGGAG 2 -- ds5001 int10--------
    rs1860885811,2
    --24774511(+) GAGTTC/TAGGGA 2 -- ut31 ds50010--------
    rs792177751,2
    F,--24774535(+) TAGGGG/CATTAG 2 -- ut31 ds50011Minor allele frequency- C:0.02EA 120
    rs2015442331,2
    C--24774556(+) AGTCAA/GGCTGG 2 -- ut31 ds50010--------
    rs1130450561,2
    C,--24774601(+) CTTTCG/AGGGCA 2 -- ds5001 ut311Minor allele frequency- A:0.50WA 2
    rs21444931,2
    C,F,H,--24774617(-) TTTCTA/GGCCTC 2 -- ut31 ds5001 ese327Minor allele frequency- G:0.13NS EA NA WA CSA 3817
    rs735914111,2
    C,--24774654(+) CAGGTA/GAGGGT 2 -- ut31 ds50012Minor allele frequency- G:0.04WA 120
    rs1904151041,2
    --24774747(+) CTAGCC/TTGTAC 2 -- ut31 ds50010--------

    HapMap Linkage Disequilibrium report for CIDEB (24774302 - 24780655 bp)
    Structural Variations (Copy Number Variations, Insertions/Deletions, Inversions)
          Database of Genomic Variants (DGV) variations for CIDEB: --

    SABiosciences Cancer Mutation PCR Assays
    QIAGEN SeqTarget long-range PCR primers in human, mouse, rat for resequencing CIDEB
    DNA2.0 Custom Variant and Variant Library Synthesis for CIDEB

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    CIDEB for disorders           About GeneDecksing

    OMIM gene information: 604441    OMIM disorders: --

    8 diseases for CIDEB:    About MalaCards
    parathyroid adenoma    intrahepatic cholangiocarcinoma    hepatitis c    cholangiocarcinoma
    adenoma    hepatitis    obesity    prostatitis

    Human Genome Epidemiology (HuGE) Navigator: CIDEB (1 document)

    Export disorders for CIDEB gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    PubMed articles for CIDEB gene, integrated from 9 sources (see all 14):
    (articles sorted by number of sources associating them with CIDEB)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Solution structure of the CIDE-N domain of CIDE-B and a model for CIDE-N/CIDE-N interactions in the DNA fragmentation pathway of apoptosis. (PubMed id 10619428)1, 2, 3 Lugovskoy A.A.... Wagner G. (1999)
    2. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S....Malek J. (2004)
    3. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (2004)
    4. Molecular cloning and characterization of CIDE-3, a novel member of the cell-death-inducing DNA-fragmentation-factor (DFF45)-like effector family. (PubMed id 12429024)1, 2 Liang L.... Li T. (2003)
    5. Mitochondria localization and dimerization are required for CIDE-B to induce apoptosis. (PubMed id 10837461)1, 3 Chen Z....Li P. (2000)
    6. CIDE, a novel family of cell death activators with homology to the 45 kDa subunit of the DNA fragmentation factor. (PubMed id 9564035)1, 2 Inohara N.... Nunez G. (1998)
    7. Peroxisome proliferator-activated receptor-gamma coac tivator-1alpha (PGC-1alpha) stimulates VLDL assembly through activation of cell death-inducing DFFA-like effector B (CideB). (PubMed id 20551328)1 Chen Z....Finck B.N. (2010)
    8. Polymorphisms in mitochondrial genes and prostate can cer risk. (PubMed id 19064571)1 Wang L....Thibodeau S.N. (2008)
    9. hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. (PubMed id 17207965)1 Lamesch P.... Vidal M. (2007)
    10. Identification of intrahepatic cholangiocarcinoma related genes by comparison with normal liver tissues using expressed sequence tags. (PubMed id 16712791)1 Wang A.G....Kim N.S. (2006)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section
    Entrez Gene: 27141 HGNC: 1977 AceView: CIDEB Ensembl:ENSG00000136305 euGenes: HUgn27141
    ECgene: CIDEB H-InvDB: CIDEB

    (According to HUGE)
    About This Section
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL,
    Wikipedia and/or GeneReviews via UniProtKB/Swiss-Prot)
    About This Section
    NameDescription
    PharmGKB entry for CIDEB Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for CIDEB Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section
    Patent Information for CIDEB gene:
    Search GeneIP for patents involving CIDEB

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, SABiosciences, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Uscn, Thermo Fisher Scientific, Gene Editing from DNA2.0, Clones from EMD Millipore, OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript and LifeMap BioReagents, PCR Arrays from SABiosciences, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, and/or Enzo Life Sciences),
    In Situ Hybridization Assays from
    Advanced Cell Diagnostics
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    GeneCards Homepage - Last full update: 19 Mar 2013 - Incrementals: 21 Mar 2013 , 15 Apr 2013 , 26 Apr 2013

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