Set Analyses:
Advanced Search

Advanced Search

 
Search By
Section (entire)
for


 



CIDEB Gene

protein-coding   GIFtS: 49
GCID: GC14M024774

Cell Death-Inducing DFFA-Like Effector B

  See related diseases
at  

(According to 1HGNC, 2Entrez Gene,
3UniProtKB/Swiss-Prot, 4UniProtKB/TrEMBL, 5OMIM, 6GeneLoc, 7Ensembl, 8DME, 9miRBase, 10fRNAdb, 12H-InvDB, 13NCBI, 14NONCODE, and/or 15RNAdb)
About This Section

TryGeneCards Plus

Aliases
Cell Death-Inducing DFFA-Like Effector B1 2 3
Cell Death Activator CIDE-B2

External Ids:    HGNC: 19771   Entrez Gene: 271412   Ensembl: ENSG000001363057   OMIM: 6044415   UniProtKB: Q9UHD43   

Export aliases for CIDEB gene to outside databases

Previous GC identifers: GC14M022146 GC14M018561 GC14M022764 GC14M023844 GC14M004889


(According to Entrez Gene, GeneCards, Tocris Bioscience, Wikipedia's Gene Wiki, PharmGKB,
UniProtKB/Swiss-Prot, and/or UniProtKB/TrEMBL)
About This Section

TryGeneCards Plus

GeneCards Summary for CIDEB Gene:
CIDEB (cell death-inducing DFFA-like effector b) is a protein-coding gene. Diseases associated with CIDEB include intrahepatic cholangiocarcinoma, and parathyroid adenoma. An important paralog of this gene is CIDEA.

UniProtKB/Swiss-Prot: CIDEB_HUMAN, Q9UHD4
Function: Activates apoptosis




(According to GeneLoc and/or HGNC, and/or
Entrez Gene (NCBI build 37),
and/or miRBase,
Genomic Views according to UCSC (hg19) and Ensembl (release 75), Regulatory elements and Epigenetics data according to QIAGEN, and/or SwitchGear Genomics)
About This Section

TryGeneCards Plus
Regulatory elements:
   Regulatory transcription factor binding sites in the CIDEB gene promoter:
         GR   Pax-5   YY1   GATA-1   c-Ets-1   HNF-4alpha1   PPAR-alpha   CREB   COMP1   GR-alpha   
         Other transcription factors

SwitchGear Promoter luciferase reporter plasmids (see all 2): CIDEB promoter sequence
   Search Chromatin IP Primers for CIDEB

Epigenetics:
DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat CIDEB


Genomic Location:
Genomic View: UCSC Golden Path with GeneCards custom track

Entrez Gene cytogenetic band: 14q12   Ensembl cytogenetic band:  14q12   HGNC cytogenetic band: 14q12

CIDEB Gene in genomic location: bands according to Ensembl, locations according to (and/or Entrez Gene and/or Ensembl if different)
CIDEB gene location

GeneLoc information about chromosome 14         GeneLoc Exon Structure

GeneLoc location for GC14M024774:  view genomic region     (about GC identifiers)

Start:
24,774,302 bp from pter      End:
24,780,636 bp from pter
Size:
6,335 bases      Orientation:
minus strand

(According to 1UniProtKB, HORDE, 2neXtProt, Ensembl, and/or Reactome, Modification sites according to PhosphoSitePlus, Specific Peptides from DME, RefSeq according to NCBI, PDB rendering according to OCA and/or Proteopedia, Recombinant Proteins from EMD Millipore, R&D Systems, GenScript, Enzo Life Sciences, OriGene, Novus Biologicals, Sino Biological, ProSpec, and/or Cloud-Clone Corp.,
Biochemical Assays by EMD Millipore, R&D Systems, OriGene, GenScript, Cell Signaling Technology, Enzo Life Sciences, and/or Cloud-Clone Corp., Antibodies by EMD Millipore, R&D Systems, Cell Signaling Technology, OriGene, Novus Biologicals, Thermo Fisher Scientific, LSBio, Abcam, Cloud-Clone Corp, and/or others.)
About This Section

TryGeneCards Plus

UniProtKB/Swiss-Prot: CIDEB_HUMAN, Q9UHD4 (See protein sequence)
Recommended Name: Cell death activator CIDE-B  
Size: 219 amino acids; 24678 Da
Subunit: Inhibited by DFFB. Interacts with DFFA and DFFB
1 PDB 3D structure from and Proteopedia for CIDEB:
1D4B (3D)    
Secondary accessions: D3DS73 Q546V8 Q9NNW9

Explore the universe of human proteins at neXtProt for CIDEB: NX_Q9UHD4

Explore proteomics data for CIDEB at MOPED

Post-translational modifications: 

  • Modification sites at neXtProt
  • Modification sites at PhosphoSitePlus

  • See CIDEB Protein Expression from SPIRE MOPED, PaxDB, and MaxQB

    REFSEQ proteins: NP_055245.2  
    ENSEMBL proteins: 
     ENSP00000451089   ENSP00000337731   ENSP00000258807   ENSP00000451744  

    CIDEB Human Recombinant Protein Products:

    Browse Purified and Recombinant Proteins at EMD Millipore
    Browse R&D Systems for human recombinant proteins
    Browse recombinant and purified proteins available from Enzo Life Sciences
    Browse OriGene full length recombinant human proteins expressed in human HEK293 cells
    OriGene Protein Over-expression Lysate for CIDEB
    OriGene Custom MassSpec
    OriGene Custom Protein Services for CIDEB
    GenScript Custom Purified and Recombinant Proteins Services for CIDEB
    Novus Biologicals CIDEB Proteins
    Novus Biologicals CIDEB Lysate
    Browse Sino Biological Recombinant Proteins
    Browse Sino Biological Cell Lysates
    Browse ProSpec Recombinant Proteins
    Cloud-Clone Corp. Proteins for CIDEB

    CIDEB Antibody Products:

    Browse EMD Millipore's Extensive Line of Mono- and Polyclonal Antibodies
    Browse R&D Systems for Antibodies
    OriGene Antibodies for CIDEB
    OriGene Custom Antibody Services for CIDEB
    Novus Biologicals CIDEB Antibodies
    Abcam antibodies for CIDEB (Q9UHD4, Q546V8)
    Cloud-Clone Corp. Antibodies for CIDEB
    ThermoFisher Antibodies for CIDEB
    LSBio Antibodies in human, mouse, rat for CIDEB

    CIDEB Assay Products:

    Browse Kits and Assays available from EMD Millipore
    OriGene Custom Assay Services for CIDEB
    Browse R&D Systems for biochemical assays
    GenScript Custom Assay Services for CIDEB
    Browse Enzo Life Sciences for kits & assays
    Cloud-Clone Corp. ELISAs for CIDEB
    Cloud-Clone Corp. CLIAs for CIDEB


    (According to HGNC, IUPHAR, InterPro, ProtoNet, UniProtKB, and/or BLOCKS, Sets of similar genes according to GeneDecks)
    About This Section

    TryGeneCards Plus
    1 InterPro protein domain:
     IPR003508 CIDE-N_dom

    Graphical View of Domain Structure for InterPro Entry Q9UHD4

    ProtoNet protein and cluster: Q9UHD4

    1 Blocks protein domain: IPB003508 Caspase-activated nuclease CIDE-N

    UniProtKB/Swiss-Prot: CIDEB_HUMAN, Q9UHD4
    Similarity: Contains 1 CIDE-N domain


    CIDEB for domains           About GeneDecksing


    (According to 1UniProtKB, Genatlas, LifeMap Discovery™, IUBMB, and/or 2DME, Human phenotypes from GenomeRNAi, Animal models from MGI Mar 06 2013, inGenious Targeting Laboratory, genOway,
    transcription factor targeting from QIAGEN and/or HOMER, miRNA Gene Targets from miRTarBase, shRNA from OriGene, siRNAs from OriGene, QIAGEN, microRNA from QIAGEN, SwitchGear Genomics, Gene Editing from DNA2.0, Clones from OriGene, GenScript, Sino Biological, DNA2.0, and Vector BioLabs, Cell Lines from GenScript, ESI BIO, In Situ Hybridization Assays from Advanced Cell Diagnostics, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Molecular Function:

         UniProtKB/Swiss-Prot Summary: CIDEB_HUMAN, Q9UHD4
    Function: Activates apoptosis

         Genatlas biochemistry entry for CIDEB:
    cell death-inducing DFFA-like effector B,interacting with the DFFA/DFFB complex and putatively involved in
    apoptotic DNA fragmentation

         Gene Ontology (GO): 2 molecular function terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005515protein binding IPI12595532
    GO:0042802identical protein binding IPI12595532
         
    CIDEB for ontologies           About GeneDecksing


    Phenotypes:
         7 MGI mutant phenotypes (inferred from 1 allele(MGI details for Cideb):
     adipose tissue  behavior/neurological  growth/size/body  hematopoietic system  homeostasis/metabolism 
     immune system  liver/biliary system 

    CIDEB for phenotypes           About GeneDecksing

    Animal Models:
         MGI mouse knock-out Cidebtm1Pli for CIDEB

       inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for CIDEB
       inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for CIDEB

       genOway customized KO model: permanent, tissue-specific or time-controlled inactivation for CIDEB
       genOway customized Knockin model: humanization, point mutation, expression monitoring, etc. for CIDEB

    miRNA
    Products:
        
    Block miRNA regulation of human, mouse, rat CIDEB using miScript Target Protectors
    3 qRT-PCR Assays for microRNAs that regulate CIDEB:
    hsa-miR-194* hsa-miR-1179 hsa-miR-3150a-3p
    SwitchGear 3'UTR luciferase reporter plasmidCIDEB 3' UTR sequence
    Inhib. RNA
    Products:
        
    OriGene RNAi products in human, mouse, rat for CIDEB
    Predesigned siRNA for gene silencing in human, mouse, rat CIDEB

    Gene Editing
    Products:
    DNA2.0 Custom Protein Engineering Service for CIDEB

    Clone
    Products:
         
    OriGene clones in human, mouse for CIDEB (see all 9)
    OriGene ORF clones in mouse, rat for CIDEB
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: CIDEB (NM_014430)
    Browse Sino Biological Human cDNA Clones
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CIDEB
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CIDEB

    Cell Line
    Products:
         
    GenScript Custom overexpressing Cell Line Services for CIDEB
    Browse ESI BIO Cell Lines and PureStem Progenitors for CIDEB 
    In Situ Assay
    Products:
       

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CIDEB


    (According to UniProtKB, COMPARTMENTS Subcellular localization database, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene.)
    About This Section

    TryGeneCards Plus

    Subcellular locations from COMPARTMENTS: 

    CompartmentConfidence
    cytosol5
    nucleus2
    endoplasmic reticulum1
    extracellular1
    lysosome1

    Gene Ontology (GO): 3 cellular component terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0005622intracellular ----
    GO:0005811lipid particle IBA--
    GO:0005829cytosol IDA12429024

    CIDEB for ontologies           About GeneDecksing


    (SuperPaths according to PathCards, Pathways according to R&D Systems, Cell Signaling Technology, KEGG, PharmGKB, BioSystems, Sino Biological, Reactome, Tocris Bioscience, GeneGo (Thomson Reuters), QIAGEN, and/or UniProtKB, Sets of similar genes according to GeneDecks, Interaction Networks according to QIAGEN, and/or STRING, Interactions according to 1UniProtKB, 2MINT, 3I2D, and/or 4STRING, with links to IntAct and Ensembl, Ontologies according to Gene Ontology Consortium 01 Apr 2014 via Entrez Gene).
    About This Section

    TryGeneCards Plus



        Pathway & Disease-focused RT2 Profiler PCR Arrays including CIDEB: 
              Neurotoxicity in human mouse rat
              Apoptosis 384HT in human mouse rat
              Apoptosis in human mouse rat

    Interactions:

        GeneGlobe Interaction Network for CIDEB

    STRING Interaction Network Preview (showing 1 interactants - click image to see more details)

    Selected Interacting proteins for CIDEB (Q9UHD41, 3 ENSP000002588074) via UniProtKB, MINT, STRING, and/or I2D (see all 6)
    InteractantInteraction Details
    GeneCardExternal ID(s)
    DFFAO002733I2D: score=2 
    DFFBO760753I2D: score=2 
    CIDEAO605433I2D: score=1 
    CIDEBQ9UHD41EBI-7062247,EBI-7062247
    -P279581EBI-7062247,EBI-6919131
    About this table

    Gene Ontology (GO): 4 biological process terms:    About this table

    GO IDQualified GO termEvidencePubMed IDs
    GO:0006915apoptotic process IDA12429024
    GO:0008630intrinsic apoptotic signaling pathway in response to DNA damage TAS10619428
    GO:0042981regulation of apoptotic process IBA--
    GO:0097194execution phase of apoptosis ISS9564035

    CIDEB for ontologies           About GeneDecksing



    (Chemical Compounds according to UniProtKB, Enzo Life Sciences, EMD Millipore, Tocris Bioscience, ApexBio, HMDB, BitterDB, and/or Novoseek, Ligands according to IUPHAR, and Drugs according to DrugBank, Enzo Life Sciences, and/or PharmGKB)
    About This Section

    TryGeneCards Plus
    Browse Small Molecules at EMD Millipore
       Browse drugs & compounds from Enzo Life Sciences
      Browse compounds at ApexBio 

    Browse Tocris compounds for CIDEB



    (Secondary structures according to fRNAdb,
    GenBank/EMBL/DDBJ Accessions according to
    Unigene (Build 236 Homo sapiens; Apr 25 2013) or GenBank,
    RefSeq according to Entrez Gene,
    DOTS (version 10), and/or AceView, transcript ids from Ensembl with links to UCSC,
    exon structure from GeneLoc, alternative splicing isoforms according to ASD and/or ECgene,
    siRNAs from OriGene, QIAGEN, shRNA from OriGene, microRNA from QIAGEN, SwitchGear Genomics,
    Tagged/untagged cDNA clones from OriGene, GenScript, DNA2.0, Vector BioLabs, Primers from OriGene, and/or QIAGEN )
    About This Section

    TryGeneCards Plus

    REFSEQ mRNAs for CIDEB gene: 
    NM_014430.2  

    6 Ensembl transcripts including schematic representations, and UCSC links where relevant:
    ENST00000554411(uc001won.3) ENST00000336557(uc001wop.3) ENST00000258807(uc001woo.3)
    ENST00000556756 ENST00000555471 ENST00000555817
    miRNA
    Products:
         
    Block miRNA regulation of human, mouse, rat CIDEB using miScript Target Protectors
    3 qRT-PCR Assays for microRNAs that regulate CIDEB:
    hsa-miR-194* hsa-miR-1179 hsa-miR-3150a-3p
    SwitchGear 3'UTR luciferase reporter plasmidCIDEB 3' UTR sequence
    Inhib. RNA
    Products:
         
    OriGene RNAi products in human, mouse, rat for CIDEB
    Predesigned siRNA for gene silencing in human, mouse, rat CIDEB
    Clone
    Products:
         
    OriGene clones in human, mouse for CIDEB (see all 9)
    OriGene ORF clones in mouse, rat for CIDEB
    OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
    GenScript: all cDNA clones in your preferred vector: CIDEB (NM_014430)
    DNA2.0 Custom Codon Optimized Gene Synthesis Service for CIDEB
    Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CIDEB
    Primer
    Products:
        
    OriGene qPCR primer pairs and template standards for CIDEB
    OriGene qSTAR qPCR primer pairs in human, mouse for CIDEB
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat CIDEB
      QuantiTect SYBR Green Assays in human, mouse, rat CIDEB
      QuantiFast Probe-based Assays in human, mouse, rat CIDEB

    Selected AceView cDNA sequences (see all 99):

    CR611009 BE206519 BC000982 BC035970 CB157532 BF925719 CB162472 AF218586 
    BM927198 AW571732 AI051238 AA236293 BG566147 AI129619 BX431518 BX431517 
    BM981976 BF513210 BX113973 BX372432 BG562967 BQ706362 AF544398 BG706442 

    GeneLoc Exon Structure


    (RNA expression data according to H-InvDB, NONCODE, miRBase, and RNAdb, Expression images according to data from BioGPS, Illumina Human BodyMap, and CGAP SAGE, Sets of similar genes according to GeneDecks, in vivo and in vitro expression data from LifeMap Discovery™, Protein expression images according to data from SPIRE 1MOPED, 2PaxDb, and 3MaxQB, plus additional links to SOURCE, and/or BioGPS, and/or UniProtKB,
    PCR Arrays from QIAGEN, Primers from OriGene, and/or QIAGEN, In Situ Hybridization Assays from Advanced Cell Diagnostics)
    About This Section

    TryGeneCards Plus

    CIDEB expression in normal human tissues (normalized intensities)
    See probesets specificity/sensitivity at GeneAnnot
    About this imageBioGPS <intensity>2/3
    CGAP TAG: TAAAAGGATG
    CIDEB Expression
    About this image


    CIDEB expression in embryonic tissues and stem cells    About this table
    Data from LifeMap, the Embryonic Development and Stem Cells Database
     selected tissues (see all 3) fully expand
     
     Kidney (Urinary System)    fully expand to see all 8 entries
             Loop of Henle Cells Loop of Henle
             Metanephros
             visceral organ/metanephros/renal cortex   
     
     Epithelial Cells
             Loop of Henle Cells Loop of Henle
     
     Liver (Hepatobiliary System)
    CIDEB Protein expression data from MOPED1, PaxDb2 and MaxQB3    About this image

    CIDEB Protein Expression

    UniProtKB/Swiss-Prot: CIDEB_HUMAN, Q9UHD4
    Tissue specificity: Highly expressed in liver and small intestine and, at lower levels, in colon, kidney and
    spleen

        Pathway & Disease-focused RT2 Profiler PCR Arrays including CIDEB: 
              Neurotoxicity in human mouse rat
              Apoptosis 384HT in human mouse rat
              Apoptosis in human mouse rat

    Primer
    Products:
    OriGene qPCR primer pairs and template standards for CIDEB
    OriGene qSTAR qPCR primer pairs in human, mouse for CIDEB
    Pre-validated RT2 qPCR Primer Assay in human, mouse, rat CIDEB
    QuantiTect SYBR Green Assays in human, mouse, rat CIDEB
    QuantiFast Probe-based Assays in human, mouse, rat CIDEB
    In Situ
    Assay Products:
     

     
    Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CIDEB

    (Orthologs according to 1,2HomoloGene (2older version, for species not in 1newer version), 3euGenes, 4SGD , 5MGI Mar 06 2013, with possible further links to Flybase and/or WormBase, and/or 6Ensembl pan taxonomic compara , Gene Trees according to Ensembl and TreeFam)
    About This Section

    TryGeneCards Plus

    This gene was present in the common ancestor of chordates.

    Orthologs for CIDEB gene from Selected species (see all 9)    About this table
    Organism Taxonomic
    classification
    Gene Description Human
    Similarity
    Orthology
    Type
    Details
    mouse
    (Mus musculus)
    Mammalia Cideb1 , 5 cell death-inducing DNA fragmentation factor, alpha more1, 5 83.33(n)1
    86.11(a)1
      14 (28.19 cM)5
    126841  NM_009894.31  NP_034024.21 
     557540455 
    lizard
    (Anolis carolinensis)
    Reptilia CIDEB6
    cell death-inducing DFFA-like effector b
    50(a)
    1 ↔ 1
    GL343400.1(249215-258491)
    tropical clawed frog
    (Xenopus tropicalis)
    Amphibia cideb1 cell death-inducing DFFA-like effector b 61.75(n)
    58.06(a)
      496919  NM_001011434.1  NP_001011434.1 
    zebrafish
    (Danio rerio)
    Actinopterygii cideb1 cell death-inducing DFFA-like effector b 55.95(n)
    49.49(a)
      553467  NM_001256257.1  NP_001243186.1 


    ENSEMBL Gene Tree for CIDEB (if available)
    TreeFam Gene Tree for CIDEB (if available)

    (Paralogs according to 1HomoloGene,
    2Ensembl, and 3SIMAP, Pseudogenes according to 4Pseudogene.org Build 68)
    About This Section

    TryGeneCards Plus
    Paralogs for CIDEB gene
    CIDEA2  CIDEC2  
    2 SIMAP similar genes for CIDEB using alignment to 2 protein entries:     CIDEB_HUMAN (see all proteins):
    CIDEA    CIDEC

    CIDEB for paralogs           About GeneDecksing



    (SNPs/Variants according to the 1NCBI SNP Database, 2Ensembl, 3PupaSUITE, 4UniProtKB, and DNA2.0, Linkage Disequilibrium by HapMap, Structural Variations(CNVs/InDels/Inversions) from the Database of Genomic Variants, Mutations from the Human Gene Mutation Database (HGMD), the Human Cytochrome P450 Allele Nomenclature Database, and the Locus Specific Mutation Databases (LSDB), Blood group antigen gene mutations by BGMUT, Resequencing Primers, Cancer Mutation PCR Arrays and Assays, and Copy Number PCR Arrays from QIAGEN)
    About This Section

    TryGeneCards Plus

    Selected SNPs for CIDEB (see all 96)    About this table    
    Genomic DataTranscription Related DataAllele Frequencies
    SNP IDValidClinical
    significance
    Chr 14 posSequence#AA
    Chg
    TypeMore#Allele
    freq
    PopTotal
    sample
    More
    ----------
    rs1389920801,2
    C,F--24774877(+) CTGCTC/TAGCCC 2 K E mis11Minor allele frequency- T:0.00NA 4546
    rs1494278711,2
    C,F--24774926(+) AACATA/GTGGCC 2 H syn12Minor allele frequency- G:0.00NA EU 5859
    rs1828161581,2
    C--24774929(+) ATATGG/TCCCAG 2 G syn10--------
    rs1861079281,2
    C--24774961(+) CCAACA/GAAGGA 2 R C mis10--------
    rs1431034691,2
    C--24774987(+) GAGAC-/AAGAGGA 1 -- int10--------
    rs1906580621,2
    C--24775023(+) GAGGAA/GGCCAT 1 -- int10--------
    rs2005824751,2
    C--24775152(+) TCTGAC/TCTGAG 1 -- spd11Minor allele frequency- T:0.00EU 1323
    rs1460366911,2
    C--24775249(+) GGTCTC/TGAGGG 2 Q R mis10--------
    rs1485536091,2
    C--24775268(+) GTACAC/AGTCAA 2 /V /L mis11Minor allele frequency- A:0.00NA 4552
    rs1473694011,2
    C--24775286(+) TCGGGC/TGATGT 2 T A mis11Minor allele frequency- T:0.00NA 4552

    HapMap Linkage Disequilibrium report for CIDEB (24774302 - 24780636 bp)

    Structural Variations
         Database of Genomic Variants (DGV) 2 variations for CIDEB:    About this table    
    Variant IDTypeSubtypePubMed ID
    esv2669637CNV Deletion23128226
    dgv1855n71CNV Loss21882294

    Site Specific Mutation Identification with PCR Assays
    SeqTarget long-range PCR primers for resequencing CIDEB
    DNA2.0 Custom Variant and Variant Library Synthesis for CIDEB

    (in which this Gene is Involved, According to MalaCards, OMIM, UniProtKB, the University of Copenhagen DISEASES database, Genatlas, GeneTests, GAD, HuGE Navigator, and/or TGDB.)
    About This Section

    TryGeneCards Plus
    OMIM gene information: 604441    OMIM disorders: --

    10 diseases for CIDEB:    
    About MalaCards
    intrahepatic cholangiocarcinoma    parathyroid adenoma    cholangiocarcinoma    hepatitis c virus
    hepatitis c    adenoma    obesity    hepatitis
    prostate cancer    prostatitis


    CIDEB for disorders           About GeneDecksing

    Genetic Association Database (GAD): CIDEB
    Human Genome Epidemiology (HuGE) Navigator: CIDEB (1 document)

    Export disorders for CIDEB gene to outside databases

    (in PubMed. Associations of this gene to articles via 1Entrez Gene, 2UniProtKB/Swiss-Prot, 3HGNC, 4GAD, 5PharmGKB, 6HMDB, 7DrugBank, 8UniProtKB/TrEMBL, 9 Novoseek, and/or 10fRNAdb)
    About This Section

    TryGeneCards Plus

    PubMed articles for CIDEB gene, integrated from 10 sources (see all 16):
    (articles sorted by number of sources associating them with CIDEB)
        Utopia: connect your pdf to the dynamic
    world of online information

    1. Solution structure of the CIDE-N domain of CIDE-B and a model for CIDE-N/CIDE-N interactions in the DNA fragmentation pathway of apoptosis. (PubMed id 10619428)1, 2, 3 Lugovskoy A.A.... Wagner G. (Cell 1999)
    2. Polymorphisms in mitochondrial genes and prostate cancer risk. (PubMed id 19064571)1, 4 Wang L....Thibodeau S.N. (amp 2008)
    3. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PubMed id 15489334)1, 2 Gerhard D.S.... Malek J. (Genome Res. 2004)
    4. Complete sequencing and characterization of 21,243 full-length human cDNAs. (PubMed id 14702039)1, 2 Ota T.... Sugano S. (Nat. Genet. 2004)
    5. Molecular cloning and characterization of CIDE-3, a novel member of the cell-death-inducing DNA-fragmentation-factor (DFF45)-like effector family. (PubMed id 12429024)1, 2 Liang L.... Li T. (Biochem. J. 2003)
    6. Mitochondria localization and dimerization are required for CIDE-B to induce apoptosis. (PubMed id 10837461)1, 3 Chen Z....Li P. (J. Biol. Chem. 2000)
    7. CIDE, a novel family of cell death activators with homology to the 45 kDa subunit of the DNA fragmentation factor. (PubMed id 9564035)1, 2 Inohara N.... Nunez G. (EMBO J. 1998)
    8. Expression of CIDE proteins in clear cell renal cell carcinoma and their prognostic significance. (PubMed id 23475172)1 Yu M....Ye J. (Mol. Cell. Biochem. 2013)
    9. Human serum activates CIDEB-mediated lipid droplet enlargement in hepatoma cells. (PubMed id 24161736)1 Singaravelu R....Pezacki J.P. (Biochem. Biophys. Res. Commun. 2013)
    10. Peroxisome proliferator-activated receptor-gamma coactivator-1alpha (PGC-1alpha) stimulates VLDL assembly through activation of cell death-inducing DFFA-like effector B (CideB). (PubMed id 20551328)1 Chen Z....Finck B.N. (J. Biol. Chem. 2010)

    (in PubMed, OMIM, and NCBI Bookshelf)
    About This Section

    TryGeneCards Plus
     ANDOR
    Aliases
    Free Text  

      Query String
    PubMed
    OMIM
    NCBI Bookshelf
      (Note: In FireFox, select the above section and copy using Ctrl-C)

    (According to Entrez Gene, HGNC, AceView, euGenes, Ensembl, miRBase, ECgene, Kegg, and/or H-InvDB)
    About This Section

    TryGeneCards Plus
    Entrez Gene: 27141 HGNC: 1977 AceView: CIDEB Ensembl:ENSG00000136305 euGenes: HUgn27141
    ECgene: CIDEB H-InvDB: CIDEB

    (According to HUGE)
    About This Section

    TryGeneCards Plus
      --

    (According to PharmGKB, ATLAS, HORDE, IMGT, LEIDEN, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL, and/or others, e.g. Wikipedia and GeneReviews, via UniProtKB/Swiss-Prot)
    About This Section

    TryGeneCards Plus
    NameDescription
    PharmGKB entry for CIDEB Pharmacogenomics, SNPs, Pathways
    ATLAS Chromosomes in Cancer entry for CIDEB Genetics and Cytogenetics in Oncology and Haematology

    (Patent information from GeneIP,
    Licensable technologies from WIS Yeda, Salk, Tufts,
    IP news from LifeMap Sciences, Inc.)
    About This Section

    TryGeneCards Plus
    Patent Information for CIDEB gene:
    Search GeneIP for patents involving CIDEB

    GeneCards and IP:
    Japan Patent Office Licenses GeneCards     European Patent Office Licenses GeneCards     Improving the IP Search



    (Antibodies, recombinant proteins, and assays from EMD Millipore, R&D Systems, OriGene, QIAGEN, GenScript, Cell Signaling Technology, Novus Biologicals, Sino Biological, Enzo Life Sciences, Abcam, ProSpec, Cloud-Clone Corp., Thermo Fisher Scientific, LSBio, Gene Editing from DNA2.0. Clones from OriGene, GenScript, Sino Biological, DNA2.0, SwitchGear Genomics, Vector BioLabs, Cell lines from GenScript, and ESI BIO, PCR Arrays from QIAGEN, Drugs and/or compounds from EMD Millipore, Tocris Bioscience, Enzo Life Sciences, and/or ApexBio, In Situ Hybridization Assays from
    Advanced Cell Diagnostics, Animal models from inGenious Targeting Laboratory, genOway)
    About This Section

    TryGeneCards Plus

     
     EMD Millipore genomic analysis products

      
     Browse Antibodies   Browse Cell Culture Products  
     Browse ELISAs   Browse Flow Cytometry Kits  
     Browse Primer Pairs   Browse Enzyme Activity Assays/Reagents  
     Browse ELISpot/FluoroSpot Kits/Development Modules   Browse TFB/Immunoprecipitation Assays  
     Browse Apoptosis Detection Kits/Reagents   Browse Ubiquitin Proteasome Pathway (UPP) Assay Kits/Reagents  
     Browse DNA Damage/Repair Kits/Reagents   Browse Luminex Assays  
     Browse Cell Selection/Detection Kits/Reagents   Browse Secondary Antibodies/Controls/Staining Reagents  
     Browse Recombinant/Natural Proteins   Browse Stem Cell Products  
     Browse cDNA Clones   Browse Proteome Profiler Antibody Arrays  
     OriGene Antibodies for CIDEB   OriGene RNAi products in human, mouse, rat for CIDEB  
     OriGene qPCR primer pairs and template standards for CIDEB   OriGene Protein Over-expression Lysate for CIDEB  
     OriGene Custom Mass Spec   OriGene clones in human, mouse for CIDEB  
     OriGene qSTAR qPCR primer pairs in human, mouse for CIDEB   Browse OriGene full length recombinant human proteins expressed in human HEK293 cells  
     OriGene ORF clones in mouse, rat for CIDEB   OriGene custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling  
     OriGene Custom Antibody Services for CIDEB   OriGene Custom Protein Services for CIDEB  

     
     
     Block miRNA regulation of human, mouse, rat CIDEB using miScript Target Protectors SeqTarget long-range PCR primers for resequencing CIDEB
     DNA Methylation CpG Assay Predesigned for Pyrosequencing in human, mouse, rat CIDEB Predesigned siRNA for gene silencing in human, mouse, rat CIDEB
     QuantiFast Probe-based Assays in human, mouse, rat CIDEB QuantiTect SYBR Green Assays in human, mouse, rat CIDEB
     PCR Arrays including human, mouse, rat CIDEB Search Chromatin IP Primers for CIDEB
     Pre-validated RT2 qPCR Primer Assay in human, mouse, rat CIDEB  GeneGlobe Interaction Network for CIDEB
     Regulatory tfbs in CIDEB promoter
     GenScript Custom Purified and Recombinant Proteins Services for CIDEB GenScript cDNA clones with any tag delivered in your preferred vector for CIDEB
     GenScript Custom Assay Services for CIDEB GenScript Custom overexpressing Cell Line Services for CIDEB
     CloneReady with Over 120,000 Genes  Gene Synthesis: Any Gene in Any Vector
     Vector-based siRNA and miRNA, Ready for Transfection Gene Mutant Library, Variants up to 10^11
     Plasmid Preparation Custom Peptide Services
     Search for Antibodies & Assays

     Search Tocris compounds for CIDEB
     Browse Sino Biological Proteins
     Browse Sino Biological Cell Lysates
     Browse Sino Biological cDNA Clones
     4000+ Proteins
     Search Sino Biological for antibodies, proteins & pathways
     Protein Production Services
     Transfection Reagents
     Protein A/G/L resins
     Isotyping reagents
     Search www.enzolifesciences.com for proteins, assays, substrates, inhibitors & antibodies

     Novus Tissue Slides
     CIDEB antibodies
     CIDEB proteins
     CIDEB lysates
     Antibodies for CIDEB
     See all of Abcam's Antibodies, Kits and Proteins for CIDEB
     Custom Antibody / Protein Production Service
     Bulk Purchasing
     Advantages of Rabbit Monoclonal antibodies
     Abcam protocols and scientific support
     Browse ProSpec Recombinant Proteins
     Proteins for CIDEB
     Antibodies for CIDEB
     ELISAs for CIDEB
     CLIAs for CIDEB



     Browse ESI BIO Cell Lines and PureStem Progenitors for CIDEB
     Gene Synthesis
     Protein Engineering
     Variant Library Synthesis
     Codon Optimization
     Protein Production and Purification
     Advanced Cell Diagnostics RNAscope RNA in situ hybridization assays for CIDEB
     SwitchGear 3'UTR luciferase reporter plasmids for CIDEB
     SwitchGear Promoter luciferase reporter plasmids for CIDEB
     ThermoFisher Antibodies for CIDEB
     Vector BioLabs ready-to-use adenovirus/AAV for human, mouse, rat CIDEB
     inGenious Targeting Laboratory: Let us create your new Knockout/Knockin mouse model for CIDEB
     inGenious Targeting Laboratory: Contact us about creating complex and humanized mouse models for CIDEB
     LSBio Antibodies in human, mouse, rat for CIDEB
    Customized transgenic rodents for:
     Humanization
     Biomarker expression
     Off-target effect monitoring
     Translational medicine
     Tissue-specific gene expresssion
     Time-controlled gene expresssion
     Browse compounds at ApexBio
           
    GeneCards Homepage - Last full update: 7 May 2014 - Incrementals: 9 May 2014 , 2 Jun 2014 , 26 Jun 2014 , 30 Jun 2014

    View Random Gene

    Category
    (GIFtS: )
    GIFtS Group
    The GeneCards human gene database gene index: 1 3 5 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z 


    Developed at the Crown Human Genome Center, Department of Molecular Genetics, the Weizmann Institute of Science

    Hot genes      Disease genes      CIDEB gene at Home site.
    Version: 3.12.166 28 Aug 2014
    hostname: 356977-web1.xennexinc.com index build: 126 solr: 1.4